Uri kunetseka nezvekugwamba kweropa here? Ungave uchinetseka nezvekuva nechirwere chemwoyo kana sitiroko. Kune vanhu vari panjodzi, vanachiremba vanokupa mhando yemushonga unozivikanwa se "blood thinner." Saka nhasi tichataura nezvemhando itsva yemushonga, asi yakakosha zvikuru. Ndiyo Direct Thrombin Inhibitors.
Zvichitaurwa zviri nyore, chii chinonzi Direct Thrombin Inhibitors idzi?
Iyi ndiyo mishonga yatinodaidza kuti inobvisa ropa, kana kuti mishonga inorwisa ropa kuti risaungane. Basa rayo nderekumisa kuumbwa kweropa risingakoshi mumuviri. Ingofungai, vanhu vazhinji pasi rose vanofa nechirwere chemwoyo. Saka mhando idzi dzemishonga dzinobatsira zvikuru mukudzivirira kuungana kweropa kuti risaungane netsinga dzeropa dzinopa nhengo dzinokosha dzakadai semwoyo neuropi.
Kunyangwe kare, mishonga iyi yaigadzirwa uchishandisa zvinhu zvakafanana nepuroteni inowanikwa mumate ezvikwekwe, mishonga yemazuva ano inogadzirwa mumarabhoritari ndiyo yava kushandiswa.
Mushonga uyu unoshandiswa pamamiriro ezvinhu api?
Vanachiremba vanokurudzira rudzi urwu rwemushonga, unonzi direct thrombin inhibitors, kudzivirira nekudzora zvirwere zvakawanda. Ngatitarisei tafura yakaita seiyi kuti ruzivo urwu ruve nyore kunzwisisa.
| Mamiriro | Tsananguro iri nyore |
|---|---|
| Chirwere cheAcute Coronary | Kudzikira kana kumira kweropa kamwe kamwe nekuda kwekuvharika kwetsinga inotakura ropa kuenda kumoyo. |
| Kuora kweropa kunokonzerwa neheparin (HIT) | Dambudziko rakaoma apo heparin yeropa shoma inokonzera kudzikira kwemaplatelet, izvo zvinozoita kuti ropa rive rakagwamba. |
| Kuumbwa kweThromboembolism yeVhena (VTE) | Ropa rinogwamba robva ranamatira mutsinga mumuviri. |
| Kudzivirira sitiroko muAtrial Fibrillation (Afib) | Dzivirira sitiroko kuvarwere vasina matambudziko evharuvhu yemoyo asi vane kurova kwemoyo kusina kurongeka (Afib). |
| Mushure mekuvhiyiwa kwekutsiva hudyu | Deredza njodzi yekugwamba kweropa mumakumbo mushure mekuvhiyiwa. |
| Kudzikira kweThrombosis yeMutsinga Wakadzika (DVT) | Kugwamba kweropa, kunyanya mutsinga yakadzika mumakumbo. |
| Kubviswa kweMapupa | Ropa rakagwamba mugumbo rinobuda robva rapinda mutsinga iri mumapapu. |
Pamusoro pezvo, mushonga uyu unopihwawo sejekiseni panguva yekurapwa kwakadai se angioplasty, iyo inovhura tsinga dzemwoyo.
Mushonga uyu unoshanda sei mumuviri?
Izvi zviri nyore kunzwisisa. Pane zvinhu zvakawanda zvinobatanidzwa mukugwamba kweropa mumuviri wedu. Pakati pazvo , "Thrombin" yakafanana nemukuru wemainjiniya wefekitori yekugwamba kweropa. Ndiye anopa mirairo yekugwamba kweropa.
Saka chinoitwa neDirect Thrombin Inhibitor iyi ndechekuti inosunga zvakananga kune chinhu chinonzi thrombin yochimisa kuita basa rayo. Zvakafanana nemunhu anosvetuka pamberi pemuchina wekugadzira ropa achikanganisa basa rake. Kana thrombin yamira kushanda, maitiro ese ekuumbwa kweropa anomira.
Asi dzimwe nguva mushonga uyu unogona kukonzera kubuda ropa rakawanda. Muzviitiko zvakadaro, pane jekiseni rinonzi Idarucizumab kuti ridzore kushanda kwepiritsi rinonzi Dabigatran . Zvisinei, hapana mushonga chaiwo wemishonga inopinzwa mutsinga (IV). Zvisinei, kana mushonga wacho wamiswa, kushanda kwawo kunopera mumuviri nekufamba kwenguva.
Ndezvipi zvakanakira mushonga uyu?
Kana tichienzanisa nemishonga yekare inobvisa ropa rakawanda, mhando itsva iyi yemishonga ine zvakanakira zvakawanda.
- Mhedzisiro yacho yakanyatsojeka:Nekuti mushonga uyu unongobatana ne thrombin chete, mhedzisiro yacho inogara yakafanana. Izvi zvinoreva kuti unogona kutarisira mhedzisiro yakafanana pese paunotora mushonga mumwe chete. Haufanire kuchinja mushonga kakawanda sezvawaizoita ne warfarin.
- Hazvideredzi maplatelet eropa: Izvi hazvideredzi maplatelet eropa semamwe mishonga.
- Hapana chikonzero chekuongororwa ropa nguva nenguva: Paunenge uchitora Warfarin, unofanirwa kuongororwa ropa nguva nenguva kuti uone huwandu hweropa rako rinogwamba (INR test). Asi mushonga uyu haudi izvozvo.
- Njodzi shoma uye nyore kushandisa: Dabigatran, iyo inotorwa sepiritsi, ine njodzi shoma yekubuda ropa zvichienzaniswa neWarfarin. Hainawo mukana wekushanda nemimwe mishonga. Zviri nyorewo kushandisa nekuti inogona kutorwa kamwe chete kana kaviri pazuva.
- Imwe nzira yakanaka: Iyi inzira yakanaka kune avo vasingakwanise kutora mushonga weHeparin.
Mushonga uyu unoshanda zvakadii? Pane njodzi here?
Ongororo yakaratidza kuti mushonga uyu wakachengeteka uye unoshanda seWarfarin kana Heparin. Zvisinei, pane imwe nyevero inokosha. Mushonga uyu haukodzeri vanhu vane mavharuvhu emwoyo. Chiremba wako achakupa mazano panyaya iyi.
Musiyano mukuru mumishonga iyi ndewekuti inogara mumuviri kwenguva pfupi.
Fungidzira, kana ukatora mushonga weWarfarin, hafu yawo inogona kugara mumuviri wako kwemaawa makumi maviri kusvika makumi matanhatu. Asi kana ukatora mushonga wakaita seDabigatran, hafu yacho inobva mumuviri wako mumaawa gumi nemaviri kusvika gumi nemana.
Chinhu chakakosha chatinofanira kunzwisisa kubva pane izvi ndechekuti haisi pfungwa yakanaka kupotsa mushonga chero upi zvawo . Kana ukarasikirwa nemushonga, simba remushonga richapera nekukurumidza, uye njodzi yekugwamba kweropa inogona kuwedzera kamwe kamwe.
Ndezvipi migumisiro nezvinetso zvinogona kuitika?
Kufanana nemishonga yese, izvi zvinogona kuva nemigumisiro yakaipa. Kunyange zvazvo mimwe iri yakajairika, mimwe inoda kuti tichenjerere zvikuru.
Mhedzisiro huru uye ine njodzi zvikuru kubuda ropa rakawanda (Matambudziko ekubuda ropa). Pamusoro pezvo, zvinotevera zvinogona kuitika:
- Kusagadzikana kwedumbu, kuzvimba (Dyspepsia)
- Marwadzo emudumbu
- Weti yebrown kana yepingi
- Musoro
- Kuderera kweropa (Hypotension)
- Kurwadziwa kwechipfuva
- Dzungu
- Kuoma kufema
- Kupindwa nechando
- Sepsis (kupindura kwakanyanya kwemuviri kune hutachiona)
- Kusungwa kwemwoyo
Ndinofanira kufonera chiremba rini?
Kana ukasangana nemigumisiro yakaipa paunenge uchishandisa mushonga uyu, zivisa chiremba wako nekukasika.
Kunyanya kana paine zviratidzo zvekubuda ropa rakawanda, idambudziko guru.Semuenzaniso, kana ronda risingamire kubuda ropa, kana tsvina yako yakasviba, kana ukarutsa ropa, kana ukanzwa musoro wakanyanya, enda kuchipatara chiri pedyo neEmergency Department (ETU) nekukasika. Usanonoka.
Mharidzo Yekuenda Nayo Kumba
- Mishonga inodzivirira ropa kubva muropa (Direct Thrombin Inhibitors) ine simba guru inodzivirira ropa kugwina. Nguva dzose tora mushonga wawakanyorerwa nachiremba wako, panguva chaiyo.
- Usapotsa mushonga wemushonga chero nechikonzero chipi zvacho. Kuita izvi kunowedzera njodzi yekugwamba kweropa. Kana ukakanganwa kutora mushonga, bvunza chiremba wako nekukasika kuti woita sei.
- Ziva zviratidzo zvekubuda ropa rakawanda (tsvina nhema, kurutsa ropa, kubuda ropa nguva dzose). Kana izvi zvikaitika, enda kuETU nekukasika.
- Mushonga uyu haukodzeri munhu wese (kunyanya avo vane mavharuvhu emwoyo), saka iva nechokwadi chekuudza chiremba wako nhoroondo yako yese yezvekurapa.
- Kana ukapihwa mamwe marapirwo (kunyangwe kubviswa kwezino), zivisa chiremba kuti uri kutora mushonga uyu.
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