Uri kuvaviwa nechinhu chisinganzwisisike paganda rako here? Chinogona kunge chiri chirwere cheExtramammary Paget's Disease (EMPD)!

Wakamboona here chigamba chitsvuku, chine makwapa, dzimwe nguva chine makwapa paganda rako, kunyanya mudumbu, muhapwa, kana munzvimbo yesikarudzi? Chinoita sechinokura zvishoma nezvishoma, uye dzimwe nguva chinokwenya, handiti? Zvakanaka, saka nhasi tichataura nezvechirwere cheganda chakadai. Vanachiremba vanochidana kuti Extramammary Paget's Disease , kana kuti EMPD muchidimbu. Hazviwanzoitiki, asi zvakakosha kuziva nezvazvo.

Chii chinonzi chirwere cheExtramammary Paget (EMPD)?

Zvichitaurwa zviri nyore, EMPD chirwere cheganda chisingawanzoitiki. Dzimwe nguva chinogona kusanganiswa nedzimwe mhando dzekenza. Asi handizvo zvinoitika nguva dzose. Idambudziko apo ganda rako rinova dzvuku, rine makwapa, kana kuti rakakora uye rinokura. Dzimwe nguva rinogona kusaonekwa kwemakore mushure mekunge chirwere chatanga.

Chinonzi "Chirwere chaPaget" zvichibva pazita raSir James Paget, chiremba wekuBritain akangwara wemuzana remakore rechi19. Zita rake rave richishandiswa kune mamwe marudzi akawanda ekenza nekuda kwemabasa ake mukurapa zvirwere. Izwi rekuti "extramammary" rinoreva "kunze kwezamu." Izvi hazvifanirwe kuvhiringidzwa nechirwere chaPaget chezasi.

Zvinofungidzirwa kuti pakati pe7% ne40% yevanhu vane chirwere cheExtramammary Paget vanogona kunge vaine kenza iri pasi peganda . Zvisinei, sezvandambotaura, EMPD haisi nguva dzose chiratidzo cheimwe chirwere. Kurapwa nekukurumidza kunogona kubatsira kuderedza zviratidzo zvako uye kubatsira kuona kenza iri pasi peganda.

Ndeapi marudzi makuru eEMPDs?

Kune mhando mbiri huru dzeEMPDs:

1. EMPD Yekutanga: Ichi chirwere cheganda chinongoerekana chaitika. Chinotanga paganda pasina chimwe chikonzero.

2. EMPD yechipiri: Izvi zvinokonzerwa negomarara riri pasi pemuviri.

Ndiani ane mukana mukuru wekuwana EMPD?

Munhu wese anogona kuwana EMPD, asi inowanikwa zvakanyanya mumapoka anotevera:

• Vanhu vane makore ari pakati pe50 ne80 .
• Zvakajairika pakati pevakadzi .
• Zvinogona kuonekwawo pakati pevarume vekuAsia .
• Vanhu vachena .

Asi zvakakosha kuyeuka kuti ichi chirwere chisingawanzoitiki.

Sei EMPD iyi ichiitika?

Chii chinokonzera EMPD yekutanga?

Kutaura chokwadi, vanachiremba havasati vaziva kuti chii chinokonzera EMPD yekutanga. Vanofungidzira kuti inogona kutanga mune mamwe marudzi emasero mumiviri yedu. Marudzi aya emasero anosanganisira:

• Masero emudumbu eApocrine gland: Aya ma "diar glands" uye ari pedyo ne "hair follicles".
• Masero eKeratinocyte stem: Aya masero anobatsira kugadzirisa ganda.
• Masero eToker: Aya masero anowanikwa muganda ('vulvar tissue') akakomberedza nipple nepaburi renhengo yemukadzi.

Chii chinokonzera EMPD yechipiri?

EMPD yechipiri inokonzerwa nekenza kune dzimwe nzvimbo mumuviri. Gomarara remudumbu rinonzi ndiro rinokonzera chikamu chimwe muzvitatu chezvirwere zveEMPD. Pamusoro pezvo, kune mamwe marudzi egomarara anogona kukonzera EMPD yechipiri:

• Kenza yekumashure
• Kenza yedundira
• Kenza yemumuromo wechibereko
• Kenza yemudumbu
• Kenza yeprostate
• Kenza yechibereko

Ndezvipi zviratidzo zveEMPD?

Chiratidzo chikuru cheEMPD mapundu eganda anoita seeczema . Tsvagiridzo yakaratidza kuti muvanhu vanosvika 65% vane EMPD, anoitika akatenderedza vulva , uye muvanhu vanosvika 20%, anoitika akatenderedza huro .

Unogona kuona nzvimbo dziri paganda rako dzine hunhu uhu:

• Seganda (`Crusty`)
• Yakashanduka kuva tsvuku (`Tsvuku`)
• Makwapa

Mavara acho anokura zvishoma nezvishoma, uye anogona kunge aine mipendero isina kurongeka. Sezvo EMPD ichienderera mberi, maronda akadzika kana mapundu anogona kutanga. Zvimwe zviratidzo zvinosanganisira:

• Kunzwa kupisa
• Ganda racho rakatsvuka uye rinonzwa kusvotwa .
• Kukwenya
• Zvinorwadza kana kuti zvinyoro
• Ganda rakazvimba (edema)

EMPD inonyanya kuitika munzvimbo dzine ma "diar glands" ako (kunyanya ma "apocrine skin glands"). Inowanzoonekwa yakatenderedza muromo wemukadzi. Inogonawo kuitika munzvimbo idzi:

• Kutenderedza anus (`Anus`)
• Nhengo yemurume
• Perineum
• Skretamu

Kashoma, EMPD inogona kuonekwawo mune dzimwe nhengo dzemuviri, dzakadai se:

• Dumbu
• Hapwa
• Bhatani redumbu
• Matako
• Nzeve, fungiro, chiso kana ganda remusoro
• Chipfuva chepazasi
• Ibvi kana chidya

Zvakakosha kuziva kuti vanhu vanosvika 10% vane chirwere chePaget chinobva kunze kwemazamu havaratidzi zviratidzo .

Dambudziko iri reEMPD rinoonekwa sei?

Kutanga, chiremba achakubvunza nezvezviratidzo zvako uye oita bvunzo yemuviri. Kana vachifungidzira kuti une EMPD, vacha:Kuongororwa kweganda kunoitirwa. Kuongororwa kweganda kunosanganisira kutora sampuli diki yeganda rako woriongorora pasi pemaikorosikopu.

Pakutarisa uchishandisa maikorosikopu, nyanzvi yezvirwere inotsvaga masero akakosha, makuru, asina kujairika anonzi "Maseru ePaget." Vanoonawo masero aya nekutarisa kuti anoita sei kumakemikari akasiyana-siyana (immunohistochemistry).

Ungaziva sei kana uine kenza ine EMPD?

Mushure mekunge maonekwa kuti mune EMPD, chiremba wenyu achaita mimwe miedzo yakawanda kuti aongorore kenza iri muganda. Miedzo iyi inogona kusanganisira:

• Kuongororwa kweUltrasound (`Ultrasound`)
• Kuongororwa kwezamu (mammogram)
• Kusvuta pap smear
• Colonoscopy kana proctoscopy
• Kuongororwa kweCT
• Cystoscopy (kuongorora dundira)
• Kuongororwa kweprostate
• Kuongororwa kweitsvo neweti (retrograde pyelogram)
• Kuongororwa kwe lymph nodes ne ultrasound kana ne tsono
• Endoscopy yepamusoro (kuongororwa kwehuro, gumbo, uye dumbu)

Ndeapi marapirwo eEMPD?

Vanachiremba vanowanzo rapa chirwere chePaget chinobva kunze kwemazamu nekuvhiyiwa.

• Kuvhiyiwa kweMohs: Mukuita uku, chiremba anobvisa ganda rakakanganiswa nerukoko, achichengetedza ganda rakapoteredza rine hutano.
• Kuchekwa kwenzvimbo yakakura: Mukuita uku, chiremba anobvisa nzvimbo yeEMPD pamwe chete nenyama ine hutano yakaipoteredza. Micheto yeronda inozokwenywa.

Dzimwe nguva vanachiremba vanovhiya vanofanira kubvisa nzvimbo yakakura yeganda nedzimwe nyama. Vamwe vanhu vane EMPD vakakomberedza vulva vangada kubviswa chikamu kana kuti yese yevulva (kuvhiyiwa kwevulva).

Funga izvi: Kana usingakwanise kuvhiyiwa nekuda kwechimwe chirwere kana hutano husina kunaka, chiremba wako anogona kukupa mamwe marapirwo akadai se:

• Kurapa nekudzivirira muviri
• Kugadzirisa ganda ne laser
• Kurapa ne Photodynamic (PDT)
• Kurapa nemwaranzi
• Mishonga inoshandiswa kurapa kenza (mishonga inouraya kenza)

Chinhu chinonyanya kukosha ndechekuti kana paine kenza iri pachena, inofanirawo kurapwa yoga.

Pane nzira yekuderedza njodzi yekubatwa neEMPD here?

Zvinosuwisa kuti hapana chatingaita kuderedza njodzi yekubatwa neEMPD.

Munhu ane EMPD angatarisira remangwana rerudzii?

Mushure mekurapwa kweEMPD, muchafanira kushanyirwa nachiremba wenyu zvakare. Izvi zvinoenderana nekuti EMPD yaive kupi. Zvakajairika kuti EMPD idzoke zvakare munzvimbo imwe chete yayakamborapwa. Saka, zvakakosha kuti murambe muchitevera mirairo yachiremba wenyu.

Chirwere cheExtramammary Paget hachiwanzoitiki apo chinopararira (metastasizes) kune dzimwe nhengo dzemuviri. Zvisinei, dzimwe nguva chinogona kupararira kuma lymph nodes kana kune dzimwe nhengo dzemuviri. Chiremba wako anogona kutsanangura zvakanakisisa zvinogoneka pachiitiko chako.

Ko EMPD inogona kudzoka here mushure mekunge yapora?

Ehe, EMPD chirwere chinogona kudzoka kunyangwe mushure mekurapwa nekupora, kunyangwe mushure memakore mazhinji. Dzimwe nguva chinogona kudzoka mushure memakore anopfuura gumi nemashanu. Ndosaka vanachiremba vachikurudzira kuti munhu agare achiongororwa kwenguva refu uye achiongororwa nguva dzose.

Kana ndine EMPD, ndinozvitarisira sei?

Chinhu chakanakisa chaungaita ndechekuramba uchienda kuna chiremba wako kuti ugare uchimutevera. Kana chiremba wako akaona zviratidzo zveEMPD ichidzoka, anogona kutanga kurapwa ipapo ipapo.

Ndinofanira kuona chiremba rini?

Kana ukaona zviratidzo zvitsva zveEMPD, kana kuti ukaona zviratidzo zvitsva, enda kuna chiremba nekukasika.

Zvakajairika kunzwa kutya, kunyara, uye kusuruvara paunoona mapundu eganda kana bundu munzvimbo ine ganda rakanyanya kuoma mumuviri wako, senge nhengo dzako dzesikarudzi. Dambudziko iri, rinonzi Extramammary Paget's Disease (EMPD), dzimwe nguva rinogona kuvhiringidzwa nedzimwe zvirwere zveganda, saka zvinogona kutora nguva kuti uwane chirwere chaicho. Kana paine kenza iri mukati mayo, EMPD inogona kutonyanya kuipa.

Zvisinei, mashoko akanaka ndeekuti vanhu vazhinji vane EMPD vanorarama hupenyu hwakajairika, hwakazara mushure mekurapwa. EMPD inowanzo rapwa nekuvhiyiwa. Kana paine kenza iri pasi payo, inofanirawo kurapwa. Sezvo chirwere cheExtramammary Paget chichigona kudzoka, kuongororwa nachiremba wako nguva dzose kunogona kubatsira kuchiona nekukurumidza kana chikadzoka.

Zvinhu zvakakosha kuti urangarire (Mharidzo Yekuenda Kumba)

• EMPD chirwere cheganda chisingawanzoitiki chinogona kunge chakabatana nekenza.
• Cherechedza chero ganda rine makwapa matsvuku, ane maronda, ane makwapa, kana kuti rakakwidibira, kunyanya rakatenderedza nhengo dzesikarudzi, muhapwa, kana mutsvina. Zviratidzo zvinogona kusanganisira kuvaviwa, kutsva, uye kurwadziwa.
• Kana ukaona chiratidzo chakadai , usanyara kana kutya, asi enda kuna chiremba nekukasika.
• EMPD inoonekwa ne biopsy yeganda.
• Kuvhiyiwa ndiko kurapwa kunonyanya kushandiswa.
• Zvakakosha kuramba uchiongororwa nachiremba, sezvo EMPD inogona kudzoka.
• Musazvidya moyo, vanhu vazhinji vane EMPD vanorarama zvakanaka mushure mekurapwa. Chinhu chikuru ndechekuongororwa nekukurumidza uye kurapwa kwakakodzera.

Kana muine mimwe mibvunzo nezvenyaya iyi, taurai nachiremba wenyu. Iye anogona kukupai mazano akakunakirai.

` Chirwere chePaget chekunze kwemazamu, EMPD, zvirwere zveganda, kenza yeganda, masero ePaget, mavanga eganda, kuvaviwa, vulva, nzvimbo yeperianal, zvirwere zveganda, kuvhiyiwa kweMohs