"Chiremba, kwave nenguva kubva pandakatanga kutora mushonga we cholesterol iyi. Ndinodzorawo kudya kwangu zvakanaka. Asi huwandu hwe cholesterol yangu hahuna kudzikira..." Unonzwawo seizvi here? Kana kuti mumwe munhu mumhuri mako ane dambudziko iri? Kutaura zvazviri, kudzora cholesterol idambudziko guru kune vamwe vanhu. Kunyangwe vanhu vazhinji vachiwana mhedzisiro yakanaka kubva kumishonga yemhando ye 'statin', vamwe havaiwane. Saka, mushonga mutsva unonzi Leqvio wakaunzwa kubatsira vanhu vakadaro. Ngatitaurei nezvazvo zvakadzama uye nhasi.
Chii chinonzi cholesterol yakakwira (Hyperlipidemia)?
Zvichitaurwa zviri nyore, Hyperlipidemia inguva kana uine marudzi akawanda emafuta (tinoadaidza kuti lipids) muropa rako. Tese tinoda mamwe mafuta mumuviri wedu. Anoita mabasa akawanda akakosha. Asi ndipo paanonyanya kuwanda ndipo panotanga matambudziko. Kana mafuta aya akakwira nekufamba kwenguva, njodzi yekurwara nezvirwere zvakakomba zvakaita sechirwere chemwoyo, sitiroko, uye kurwara kwemoyo inowedzera zvakanyanya.
Tinowanzo taura nezvemhando mbiri huru dzemafuta.
| Rudzi rwemafuta | Zvichitaurwa zviri nyore... |
|---|---|
| Kolesteroli yeLDL (Low-Density Lipoprotein) | Izvi ndizvo zvatinodaidza kuti "cholesterol yakaipa" nekuti inosara pamadziro etsinga dzeropa, yodzivhara zvishoma nezvishoma zvokonzera chirwere chemwoyo. |
| HDL (High-Density Lipoprotein) cholesterol | Izvi zvinonzi "cholesterol yakanaka" nekuti zvinobatsira kutakura cholesterol yakaipa (LDL) kuenda kuchiropa nekuibvisa mumuviri. |
Pamusoro pezvo, kune rumwe rudzi rwemafuta anonzi triglycerides. Hazvina kunaka kuva nawo akawandisa.
Ndezvipi zvikonzero zve cholesterol yakakwira?
Kazhinji, izvi zvinokonzerwa nekusanganiswa kwemararamiro edu, kudya kwatinoita, uye zvimwe zvirwere.
- Zvekudya Nezvinwiwa: Nyama tsvuku, masoseji, bhekoni, nezvikafu zvine mafuta (mupunga wakakangwa, khuthu, paratha) zvine mafuta akawanda akazara. Kudya izvi kunowanzo wedzera cholesterol.
- Mararamiro:Zvinhu zvakaita sekusvuta fodya, kunwa doro zvakanyanya, kushushikana, uye kusaita maekisesaizi zvine simba guru pakuwedzera kwecholesterol mumuviri.
- Zvimwe zvirwere: Zvirwere zvakaita sechirwere cheshuga, matambudziko echiropa kana itsvo, hypothyroidism, uye sleep apnea zvinogonawo kukonzera cholesterol yakakwira.
Chinangwa chikuru chekurapa ndechekuderedza huwandu hwemafuta aya "akaipa" muropa. Izvi zvinogona kuderedza njodzi yezviitiko zvakakomba zvakaita sekurwadziwa kwemoyo uye sitiroko.
Mushonga weLeqvio unoshanda sei?
Mastatin ndiwo mushonga mukuru we cholesterol. Zvisinei, vamwe vanhu havaderedzi cholesterol yavo zvakanyanya sezvavaida kunyangwe vachitora mishonga iyi uye vachitevera kudya kwakanaka. Vanhu vane chirwere chemajini chinonzi "primary hyperlipidemia" vangada mishonga inopfuura imwe chete.
Leqvio mushonga mutsva wauya kuzobatsira vanhu ava. Chinhu chinoshanda mairi ndiInclisiran. Ndeweboka remishonga inonzi `small interferencing RNA (siRNA)`.
Zvichitaurwa zviri nyore, mushonga uyu unowedzera kugona kwechiropa kupinza "cholesterol yakaipa" (LDL) muropa. Zvikuru sei, unobatsira chiropa kuziva zvidimbu zveLDL. Mushure mekunge chiropa chapinza zvidimbu izvi zveLDL, chinozvishandisa kana kuzvibvisa mumuviri. Izvi zvinoderedza zvakanyanya huwandu hweLDL muropa.
Iyi nzira yakasiyana zvachose nekushanda kwemishonga yestatin.
Pane munhu ane cholesterol anogona kushandisa Leqvio here?
Kwete. Uyu mushonga hausi wemunhu wese. Leqvio inotenderwa kuvanhu vatove vari pakudya uye vari kutora statin yakawanda, asi vachiri necholesterol yakakwira .
Mushonga uyu unogona kukurudzirwa, kunyanya kune vanhu vane chirwere chemajini chinonzi `Heterozygous Familyal Hypercholesterolemia (HeFH).` Kana uine cholesterol yakakwira uye huwandu hwako husiri kudzikira kunyangwe uchitora statins uye uchitevera kudya kune hutano, chiremba wako anogona kutaura newe nezveLeqvio. Chiremba wako chete ndiye anogona kusarudza kana izvi zvakakunakira.
Ndingawana sei mushonga uyu?
Leqvio haisi piritsi, ijekiseni . Ijekiseni repasi peganda. Haugone kuripa kumba. Rinopihwa nenyanzvi yehutano (chiremba kana mukoti) muchipatara kana kukiriniki.
Purogiramu yekubaiwa nhomba ndeiyi inotevera:
1. Kubaiwa kekutanga: Uchapihwa kubaiwa kekutanga kamwe chete.
2. Kubaiwa kechipiri:Jekiseni rechipiri rinopihwa mwedzi mitatu mushure mekutanga.
3. Mushure meizvozvo: Mushure meizvozvo, unofanira kubayiwa jekiseni rimwe chete mwedzi mitanhatu yega yega .
Jekiseni iri rinogona kuiswa muhudyu, mudumbu, kana kumashure kweruoko. Zvakakosha kuti uwane jekiseni rako nenguva uye usapotsa nguva yekusangana nevamwe.
Chii chaunoziva nezvekubudirira kwaLeqvio?
Zvidzidzo zvitatu zvikuru zvakaitwa kuti zvionekwe kuti Leqvio inoshanda uye yakachengeteka sei. Zvidzidzo izvi zvakaitwa kwemwedzi gumi nemisere.
- Zvidzidzo zviviri: Vatori vechikamu vaisanganisira vanhu vane chirwere chemwoyo vakatadza kuderedza huwandu hwecholesterol yavo kunyangwe vakashandisa statins.
- Mune imwe ongororo, vatori vechikamu vaive avo vane chirwere chemafuta chinonzi `HeFH`.
Muzvidzidzo izvi, boka rimwe rakapihwa mushonga weLeqvio uye rimwe boka rakapihwa mushonga we placebo usina kubatsira. Mhedzisiro yacho yaive yakajeka.
| Chikwata | Kuchinja kwemazinga e "cholesterol" yakaipa (LDL) mushure memwedzi gumi nemisere |
|---|---|
| Avo vakagamuchira Leqvio | Paavhareji, yaderera ne40% - 51% . |
| Avo vakagamuchira placebo (mushonga wenhema) | Kuwedzera kweavhareji ndeye 1% - 8% . |
Mhedzisiro iyi inoratidza kuti Leqvio mushonga unogona kuderedza zvakanyanya huwandu hweLDL cholesterol husingadzorwe ne statins. Huwandu hwecholesterol hunowanzotanga kudzikira mukati memwedzi mitatu yekutanga.
Mushonga uyu unoderedza njodzi yekurwara nemoyo uye sitiroko here?
Uyu mubvunzo unokosha zvikuru. Mishonga yestatin yakaratidzwa kuti inoderedza cholesterol yeLDL uye inoderedza njodzi yekurohwa nemoyo uye sitiroko. Asi Leqvio mushonga unoshanda zvakasiyana.
Ongororo dziripo pari zvino dzinoratidza kuti Leqvio inogona kuderedza zvakanyanya cholesterol yeLDL. Zvisinei, zvidzidzo izvi zvakaitwa kwenguva pfupi, inenge mwedzi gumi nemisere. Saka, nguva iyoyo haina kukwana kuona kana mushonga wacho uchinyatsoderedza njodzi yekurwara nemoyo uye sitiroko.
Zvisinei, kudzikira kukuru kweLDL cholesterol kunoratidza kuti njodzi iyi inogona kudzikira mune ramangwana. Dzimwe ongororo dzenguva refu dziri kuitwa kusimbisa izvi.
Migumisiro yacho uye nzira yekuzvigadzirisa nayo?
Kufanana nemushonga upi zvawo, Leqvio inogona kukonzera migumisiro midiki. Inonyanya kuitika ndeyekuita panzvimbo yekubaiwa jekiseni .
- Kutsvuka panzvimbo yekubaiwa jekiseni
- Kukwenya
- Marwadzo
Nekuda kwechikonzero ichi, nyanzvi yehutano inopa mushonga wekudzivirira chirwere haizopi mushonga wekudzivirira chirwere munzvimbo yakapiswa nezuva, ine mapundu, kana ine hutachiona. Kana wakambobayiwa jekiseni kare uye wakamborwadziwa zvakanyanya, taurira chiremba kana nesi. Vanogona kusarudza imwe nzvimbo.
Kunze kweizvi, mimwe migumisiro inogona kuitika. Kana ukaona zviratidzo zvisingawanzoitiki, taura nachiremba wako nekukasika.
Pari zvino hapana hukama huripo pakati peLeqvio nemimwe mishonga. Zvisinei, zvakakosha kuudza chiremba wako nezvemishonga yese, mavhitamini, uye mishonga yemiti yauri kutora.
Mharidzo Yekuenda Nayo Kumba
- Leqvio mushonga mutsva wekudzivirira cholesterol.
- Izvi zvinokurudzirwa kuvanhu vane cholesterol yakakwira vasingakwanise kudzorwa nemishonga yestatin uye kudya.
- Uyu mushonga wekudzivirira chirwere unopiwa nenyanzvi yezvehutano mwedzi mitanhatu yega yega (mushure mekupiwa mishonga miviri yekutanga).
- Ongororo dzakaratidza kuti izvi zvinoshanda zvikuru mukuderedza huwandu hwe "cholesterol" yakaipa yeLDL.
- Chiremba wako chete ndiye anogona kusarudza kana mushonga uyu wakakunakira, saka taura nachiremba wako nezvazvo.
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