Ngatidzidzei nezve biopsy yetsandanyama. Ungadawo izvi here?

Wakambonzwa nezve 'Muscle Biopsy' here? Pamwe iwe kana mumwe munhu waunoziva akaudzwa nachiremba kuti aite izvi. Chii chaizvo? Sei zvichiitwa? Ngatitaurei nezvazvo nemashoko akareruka, kuti munzwisise. Hapana chikonzero chekutya, zvinowanzoitirwa kubatsira kuziva kuti dambudziko rako nderei chaizvo.

Chii chinonzi biopsy yetsandanyama?

Zvichitaurwa zviri nyore, biopsy yetsandanyama inzira iyo chidimbu chidiki chenyama chinotorwa kubva mutsandanyama yako, kureva, kubva mutsandanyama mumuviri wako, choongororwa. Izvi zvinoitirwa kuona kana uine chero chirwere (`myopathies`) chinokanganisa tsandanyama dzako. Chiremba anotumira sampuro yetsandanyama yemapfupa kurabhoritari. Ikoko, vanoitarisa pasi pemaikorosikopu kuti vaone kana paine zvisina kunaka kana matambudziko. Zvakafanana nekucheka jira wotarisa kana shinda dzacho dzakanaka kana kuti kwete.

Ndirini pandinofanira kuongororwa tsandanyama?

Fungidzira kuti wanga uchinzwa kusasimba kwetsandanyama dzako kwenguva yakati, kana kuti tsandanyama dzako dziri kurwadza, kuvava, kana kuti uine zvimwe zviratidzo zvisingawanzoitiki (zviratidzo zve 'myopathy'). Ipapo chiremba anogona kukuudza kuti unofanira kuvhiyiwa ne biopsy iyi. Asi havazoiti ipapo ipapo.

Vanachiremba vanowanzoita mimwe miedzo mishoma kutanga:

• Kuongororwa kwemuviri nekwetsinga : Uchaongororwa zvakakwana kuti uone kuti tsinga dzako dziri kushanda sei.
• Kuongororwa kweropa : Semuenzaniso, bvunzo inotarisa enzyme inonzi creatine kinase, kana bvunzo dzemajini dzinogona kuitwa.
• Kuongororwa kwemifananidzo : Zvinhu zvakaita seMRI scans neCT scans.
• Zvidzidzo zvekufambisa mitsipa uye electromyography (EMG) : Izvi zvinotarisa kuti mashoko anofamba sei pakati petsinga dzako netsandanyama, uye kuti dziri kushanda sei.

Kunyangwe nebvunzo idzi, dzimwe nguva chikonzero chaicho chechirwere hachigone kuzivikanwa. Ndipo apo vanachiremba vanoraira kuti vaongororwe tsandanyama kuti vawane rumwe ruzivo uye vaongorore chirwere chacho .

Ungangoda kuongororwa tsandanyama kana chiremba wako achifungidzira kuti une chimwe chezvirwere zvinotevera:

• Kusashanda kwetsandanyama : Mienzaniso inosanganisira Duchenne muscular dystrophy, Becker muscular dystrophy, uye myotonic dystrophy.
• Utachiona hwezvipembenene : Utachiona hwakaita setrichinosis netoxoplasmosis hunokanganisa tsandanyama dzako.
• Zvirwere zvetsandanyama zvinozvimba: zvakaita sepolymyositis uye dermatomyositis.
• Miropati yemuviri : Semuenzaniso, chirwere chePompe nezvimwe zvirwere zvekuchengetedza glycogen.
• Myopathies dzekuzvarwa nadzo : Matambudziko aripo pakuzvarwa, akadai se nemaline myopathy.
• Mishonga ine chepfu : Zvirwere zvinogona kuitika kana ukashandisa mimwe mishonga kwenguva refu, semuenzaniso ma steroids kana ma statins.

Ndedzipi tsandanyama dzinowanzo sarudzwa kuti dziongororwe?

Kuongororwa uku kunowanzo torwa kubva kune imwe yetsandanyama dzakasiyana-siyana mumuviri wako. Tsandanyama dzinonyanya kuzivikanwa ndedzinotevera:

• Makumbo emakumbo mana (quadriceps) : Boka guru remhasuru dziri pamberi pechidya chako.
• Deltoid : Tsandanyama inobatanidza mberi, divi, uye kumashure kwefudzi rako.
• Bicep : Tsandanyama iri pamberi peruoko rwako rwepamusoro, pakati pefudzi negokora.

Chiremba achada kuva nechokwadi chekuti tsandanyama yakasarudzwa kuti iongororwe haina kusimba zvakanyanya kana kuti ine zvimwe zviratidzo. Zvisinei, chiremba achadawo kuva nechokwadi chekuti tsandanyama haina kusimba zvakanyanya, haina kubayiwa jekiseni munguva pfupi yapfuura, kana kuti yakakuvara. Izvi zvinogona kukanganisa mhedzisiro yeopia uye zvingasapa ruzivo rwakarurama.

Ndinofanira kugadzirira sei kuongororwa kwetsandanyama?

Chiremba wako achakutsanangurira zvakadzama nezve biopsy uye achakupa mirairo yekuti ungagadzirira sei. Zvakakosha kutevedzera mirairo iyi nemazvo. Kana usina kunzwisisa chimwe chinhu kana kuti uine mibvunzo, usatya kubvunza chiremba wako.

Kazhinji, unofanira kungwarira nezvezvinhu izvi:

• Kana wakambobayiwa tsandanyama, wakamboongororwa tsandanyama dzakadai seEMG, kana kukuvara kwetsandanyama dzako mumwedzi mitanhatu yapfuura, unofanira kuudza chiremba wako.
• Chiremba wako anogona kukuudza kuti urege kutora mishonga inorwisa ropa senge aspirin mazuva mashoma biopsy isati yaitwa kudzivirira matambudziko ekubuda ropa. Asi, zvakanaka kuti usarege kutora mimwe mishonga kusvika chiremba wako akuudza kuti udaro.
• Unogona kukumbirwa kutsanya kwemaawa mashoma usati waongororwa, usina kudya kana kunwa chero chinhu (kunze kwemvura).
• Kana ukapihwa mushonga wekunyaradza kana wekutindivadza panguva iyi, uchada mumwe munhu kuti akuendese kumba mushure mekuongororwa kwemuviri.

Ndeipi nzira yekuongorora tsandanyama?

Matanho ekuongorora tsandanyama anosiyana zvishoma zvichienderana nenzira inoshandiswa. Kune nzira mbiri huru: ``open``` biopsy`` uye ``nedle`` biopsy``. Chero nzira, iwe (kana mwana wako) munogona kupihwa ``sedation``` kana ``general anesthesia`` isati yasvika.

Maitiro ekuita biopsy yetsandanyama yakavhurika

Matanho e biopsy yemhasuru yakavhurika anowanzo kuve anotevera:

• Chiremba anotanga achenesa nzvimbo yakachekwa zvakanaka nemushonga unouraya utachiona.
• Zvadaro, mushonga unotindivadza unopinzwa munzvimbo iyi, saka hauzonzwi kurwadziwa kana pachekwa.
• Zvadaro, ganda rako richachekwa neganda rine urefu hwemasendimita mana kusvika matanhatu.
• Chiremba achaparadzanisa ganda rako, mafuta ari pasi peganda (subcutaneous fat), neganda rinofukidza tsandanyama (muscle fascia - connective tissue), uye ozoenda kune tsandanyama iri pasi.
• Kubva ipapo, tsandanyama diki inochekwa.
• Zvadaro chiremba anovhara tsandanyama neganda zvakare ne sutures.
• Ronda racho rakafukidzwa nemishonga, mabhandeji negauze.

Maitiro ekuita biopsy yetsandanyama yetsono

Matanho e biopsy yetsandanyama yetsono anowanzo kuve anotevera:

• Chiremba anotanga achenesa nzvimbo ichaongororwa nekushandisa mushonga unouraya utachiona.
• Zvadaro vanobaya jekiseni remushonga unonyaradza marwadzo munharaunda, kuitira kuti usazonzwa kurwadziwa panguva yekuongorora.
• Chiremba achacheka ganda rako kadiki-diki.
• Tevere, mudziyo wekuongorora tsananguro unopinzwa nepaburi diki. Izvi zvinowanzoita saizi yepenzura.
• Muchina we ultrasound (ultrasound imaging) unoshandiswa kutungamira mudziyo uyu kusvika kune tsandanyama.
• Chiremba anoshandisa chishandiso ichi kucheka zvidimbu zvidiki zvetsandanyama. Kazhinji, sampuli dzinosvika nhatu kana ina dzinotorwa.
• Mushure mekubvisa huwandu hunodiwa hwenyama, mudziyo wacho unobviswa, kumanikidzwa kunoiswa panzvimbo yacho kwenguva yakati kuti ropa risabude, mushonga unoiswa paronda, uye jira reganda nemabhandeji zvinovharwa.

Izvi zvinorwadza zvakadini?

Kana ukaitwa biopsy iyi uchishandiswa anesthesia, hauzonzwi kurwadziwa. Kana ukaitwa uchishandiswa anesthesia yemunzvimbo, kurwadziwa kwacho kuchava kushoma, kana kuti kunenge kusina. Zvisinei, unogona kunzwa kudhonzwa zvishoma kana kudhonzwa.

Mushure mekuongororwa, unogona kunzwa kurwadziwa kudiki panzvimbo yekuongorora kwemuviri kwemazuva maviri kusvika matatu. Kunyanya kana wakaongororwa kwemuviri, nzvimbo yacho inogona kunge ichirwadza kweinenge vhiki. Panogonawo kunge paine maronda akakomberedza nzvimbo yacho.

Zvakanaka kubvunza chiremba wako kuti chii chinogona kuitwa pakurwadziwa uye kuti ndeapi mishonga yaunofanira kutora.

Chii chinoitika mushure mekuongororwa kweropa?

Kana wakapihwa mushonga wekunyaradza kana weanesthesia, uchaendeswa kukamuri rekupora kwenguva pfupi mushure mekuongororwa kweropa. Uchagara ikoko kusvika mushonga wacho wapera. Unogona kudzokera kumba, asi unofanira kukumbira mumwe munhu kuti akuendese kumba. Chiremba wako achakupa mirairo yekuti ungachengeta sei ronda re biopsy.

Chiremba anoshandisa makemikari akakosha kuti akurumidze kuomesa tsandanyama dzakatorwa kubva mu biopsy (`flash freeze`). Izvi zvinoitirwa kuti nyama yacho igare yakachena uye yakakodzera kuongororwa. Zvadaro inotumirwa ku lab. Kune `nyanzvi yezvirwere inyanzvi yezvirwere zvetsinga`. Iye achaongorora sampuro nokungwarira pasi pe microscope. Dzimwe nguva nyanzvi ichaita mimwe miedzo pa sampuro. Semuenzaniso, vachashandisa madhayi akakosha (`stains`) kana kutarisa mamwe ma `antibodies`.

Pane njodzi here pakuongorora tsandanyama?

Matambudziko anokonzerwa nekuongorora tsandanyama haawanzoitiki. Zvisinei, pane zvinhu zvishoma zvinogona kuitika mune zvisingawanzoitiki:

• Kutapukirwa kweronda.
• Kubuda kwetsandanyama neparonda ('hayina yemhasuru').
• Kuvhurwazve kweronda mushure mekunge machira asunungurwa.
• Kukuvara netsaona kukuvadzwa kwetsandanyama, tsinga, kana tsinga dzeropa kusingatarisirwi.

Vanga rinogona kuramba riri panzvimbo yakaongororwa. Varidzi veganda revamwe vanhu vanoonekwa zviri nyore kupfuura vamwe.

Ndichagamuchira riini mushumo wacho?

Mushure mekuongororwa kweropa, kumirira mhinduro kungangove chinhu chakaomesesa. Chiremba wako achakutsanangurira kuti uchawana sei uye riini mushumo. Zvinogona kutora mazuva mashoma, kana kuti zvinogona kutora anopfuura vhiki. Kana mushumo ukasadzoka pazuva rawakaudzwa nachiremba wako, fonera chiremba wako zvakare womubvunza nezvazvo.

Mushumo wacho unoti chii nezve?

Mushumo we biopsy yetsandanyama une ruzivo nezvehunhu hwetsandanyama yakatorwa. Izvi zvinogona kusanganisira zvinhu zvakaita se:

• Zvinhu zvakaita semaumbirwo emhasuru dzemhasuru (kureva masero emhasuru), hutano hwadzo, uye "zera" radzo.
• Ruzivo nezvemamwe masero ari munyama iyoyo, semuenzaniso, masero etsinga (neurons).
• Zvinhu zvakaita sekuzvimba, kusashanda zvakanaka kwemitochondrial, kusashanda zvakanaka kweglycogen uye lipid storage.

Chiremba wako achakutsanangurira zviri mumushumo uyu uye zvazvinoreva.

Dzimwe nguva, biopsy inogona kutaridzika zvakanaka, kana kuti panogona kunge paine zviratidzo zvidiki zvechirwere. Muchiitiko ichi, dzimwe nguva inonzi "unspecified myopathy." Izvi zvinodaro nekuti biopsy inogona kunge isina kuwana nzvimbo chaiyo yechirwere, kana kuti chirwere chinogona kunge chichiri mumatanho ekutanga. Kana izvi zvikaitika, ungangofanira kuverengerwazve tsandanyama.

Kana paine dambudziko nemushumo wacho, chii chaunotevera kuita?

Mhedzisiro yekuongorora tsandanyama inogona kazhinji kuona chirwere chetsandanyama (`myopathy`).

Kana ukaonekwa uine chimwe chirwere, chiremba wako achakutsanangurira uye achakurukura zvaunofanira kuita zvinotevera. Pamwe chete, muchagadzira hurongwa hwekurapa hunokushandirai zvakanyanya. Usazvidya mwoyo, chiremba wako achakubatsira.

Unofanira kutaura nachiremba rini?

Kana ukaona chimwe kana zvimwe zvezviratidzo zvinotevera zvekuti nzvimbo yako ye biopsy ine hutachiona, unofanira kufonera chiremba wako nekukasika:

• Kuzvimba kwakakomberedza ronda, kutsvuka, kana kuchinja ruvara rweganda zvakajairika.
• Ganda rakatenderedza ronda rinopisa kupfuura dzimwe nzvimbo.
• Urwa kana chimwe chinwiwa chinobuda muronda (`Urwa kana kubuda kwemvura`).
• Kurwara nefivha.
• Kunzwa kuneta zvakanyanya ('Kuneta').

Kuongororwa kwetsandanyama kunogona here kuongorora MS (Multiple Sclerosis)?

Kuongororwa kwetsandanyama hakuwanzo shandiswa kusimbisa kuongororwa kweMS (Multiple Sclerosis). Zvisinei, chiremba anogona kukurudzira kuongororwa uku kuti abvise mamwe mamiriro ane zviratidzo zvakafanana neMS.

Zvakajairika kunzwa kutya uye kuzvidya mwoyo paunoona kuti unoda kuongororwa tsandanyama. Uye zvakajairikawo kunzwa kuzvidya mwoyo paunenge wakamirira mhinduro. Chiremba wako achaziva nezvemigumisiro yese inogona kuitika nekuda kwekuongorora uku, saka usatya kubvunza chero mibvunzo yaungave nayo. Kana mushumo wako wekuongorora unoratidza kuti pane chisina kumira zvakanaka, edza kufunga nezvazvo sedanho rekutanga parwendo rwako rwekupora. Chiremba wako achashanda newe kuti aite sarudzo dzakakosha nezvehutano hwako.

Chii chinonyanya kukosha chatinofanira kudzidza kubva munyaya iyi?

Zvakanaka, saka chinhu chakakosha kurangarira kubva pane zvatataura nezvazvo ndechekuti kuongororwa kwetsandanyama bvunzo yakakosha zvikuru inobatsira kuona dambudziko kana chirwere chiri mutsandanyama dzako nemazvo.

Izvi zvingaita sekunge zvinokutyisa zvishoma. Asi zvinogona kukubatsira kuti uwane chirwere chakarurama uye kutanga kurapwa kwakakodzera kwauri. Kana uine mibvunzo kana zvinokunetsa, iva nechokwadi chekukurukura nezvazvo nachiremba wako. Yeuka, iyi idanho rakakosha mukunzwisisa chirwere chako uye kuchigadzirisa nemazvo.

Kuongororwa kwetsandanyama , Kuongororwa kwetsandanyama, myopathy, kushaya simba kwetsandanyama, chirwere chetsandanyama, kuongororwa, bvunzo dzekurapa, kuvhiyiwa