Mwana wako anowana mavara akadai here? Ngatidzidzei nezve Neonatal Lupus!

Zvakajairika kuti unzwe kutya kana ukangoerekana waona mavanga matsvuku pamuviri wemwana wako achangoberekwa, kana kuti chiremba akataura chimwe chinhu nezvekurova kwemoyo wemwana wako. Dzimwe nguva zvinhu izvi zvinogona kukonzerwa nechirwere chinonzi Neonatal Lupus. Nhasi, tichataura nezvazvo zvakadzama, sekunge waizotaura neshamwari.

Chii chinonzi Neonatal Lupus?

Zvichitaurwa zviri nyore, Neonatal Lupus chirwere chinogona kukanganisa mwana ari mudumbu (fetus) kana kuti mushure mekuzvarwa (infant). Kazhinji, chinokonzera shanduko dzenguva pfupi, dzisina njodzi, dzakadai semapundu paganda. Izvi zvinowanzopera zvega mwana asati asvitsa gore. Zvisinei, dzimwe nguva Neonatal Lupus inogona kukanganisa moyo wemwana.

Dambudziko guru rinogona kuitika munyaya iyi nderekuti "autoimmune congenital heart block." Kureva kuti, "Neonatal Lupus" iyi inodzivirira moyo wemwana kurova zvakanaka. Kuvhara kwemoyo uku kunogona kuisa upenyu panjodzi kana kwakanyanya, asi kunogona kurapwa kazhinji.

Kana mwana wako akaonekwa aine chirwere cheLupus chisingaperi, zvakakosha kutevedzera mirairo yechikwata chekuchengeta mwana wako nokungwarira. Vachatsanangura kuti kuongororwa kwacho kuchakanganisa sei mwana wako uye kana kurapwa kuchizodiwa.

Izvi zvine chekuita nechirwere chevakuru chinonzi lupus (Systemic Lupus Erythematosus - SLE) here?

Kwete, musavhiringe zvinhu zviviri izvi. Lupus yevana vacheche haisi chirwere chimwe chete neSystemic Lupus Erythematosus (SLE), yatinowanzodaidza kuti lupus. Idambudziko rakasiyana rine zvikonzero zvaro uye marapirwo aro.

Lupus yemwana achangoberekwa inokonzerwa nemamwe marudzi ema antibodies, akadai se anti-SSA, anti-SSB, uye anti-U1-RNP, anopfuudzwa kubva kuna amai kuenda kumwana kuburikidza ne placenta. Ma antibodies aya mapuroteni anorwisa masero ane hutano mumuviri wedu zvisirizvo. Kazhinji, ma antibodies aya haakanganisi mwana ari kukura mudumbu. Asi dzimwe nguva, anogona kurwisa masero ane hutano emwana, kunyanya masero emwoyo.

Lupus yevana vacheche inongowanikwa chete muvana vane amai vane ma antibodies aya chaiwo. Izvi zvinowanzoreva kuti amai vane chirwere che autoimmune. Semuenzaniso, Sjögren's syndrome, SLE, kana chirwere che mixed connective tissue. Zvisinei, dzimwe nguva ma antibodies aya anogona kuvapo mumuviri pasina zviratidzo. Mune zvimwe zviitiko, Lupus yevana vacheche inogona kuva chiratidzo chekutanga chekuti amai vane rimwe kana akawanda ema antibodies aya uye kuti vanogona kutanga chirwere che autoimmune mune ramangwana.

Yeuka kuti kana uine chirwere che autoimmune, hazvirevi kuti mwana wako achave ne Neonatal Lupus. Kutaura zvazviri, pane mukana wekuti mwana wako asave ne Neonatal Lupus. Asi, ichi chinhu chaunofanira kuziva uye kutaura nachiremba wako nezvacho.

Mamiriro ezvinhu aya akajairika zvakadii?

Lupus yevana vacheche haisi chinhu chinowanzoitika. Dambudziko rayo guru, autoimmune congenital heart block, rinokanganisa vacheche vari pasi pe2% vanoberekwa naamai vane ma antibodies e anti-SSA, anti-SSB, kana anti-U1-RNP. Zvisinei, kana wakambova ne autoimmune congenital heart block mupamuviri wapfuura, uri panjodzi huru yekuzoiwana zvakare mupamuviri unotevera.

Ndezvipi zviratidzo zve `(Neonatal Lupus)`?

Chiratidzo chinonyanya kuoneka mapundu paganda. Izvi zvinogona kuonekwa pakuzvarwa, kana kuti zvinogona kuonekwa mukati memwedzi mishoma yekutanga yehupenyu. Mapundu aya ndeenguva pfupi uye haana njodzi. Anoonekwa serin'i yakatenderera ine mupendero une ruvara (kazhinji katsvuku). Rin'i yega yega ine pakati pakajeka (kureva, ruvara rweganda rwakajairika).

Zvingangoita kuti uchaona maronda aya pamusoro pemusoro wemwana wako nekumeso. Zvisinei, anogonawo kuonekwa pachipfuva, mumaoko, nemakumbo. Maronda aya akafanana neaya anoonekwa muchirwere chinonzi ``subacute cutaneous lupus.'' Ndosaka achinzi ``neonatal lupus.''

Kune zvimwe zviratidzo zvenguva pfupi uye zvisingakuvadzi zvakare. Izvi ndeizvi:

• Kuderera kwehuwandu hwemasero matsvuku eropa (anemia).
• Maplatelet akaderera (masero anobatsira kuumbwa kweropa) (thrombocytopenia).
• Kuwanda kwemasero machena eropa (neutropenia).
• Ma enzymes echiropa akakwira.

Zviratidzo izvi zvese zvinopera kana ma antibodies kubva kuna amai abviswa zvachose mumuviri wemwana. Anowanzova nani pakati pemwedzi mitanhatu nepfumbamwe yekuzvarwa.

Lupus yevana vacheche uye Heart Block

Sezvatakambotaura, Lupus yeVacheche inogona kukonzera dambudziko guru rinonzi autoimmune congenital heart block. Iri idambudziko rine chekuita nemagetsi emwoyo wemwana. Kurova kwemoyo wemwana kunodzorwa nemagetsi anofamba nepakati pemoyo. MuLupus yeVacheche, ma antibodies anobva kuna amai anorwisa boka remasero anodzora mashandiro emagetsi emwoyo, anonzi AV node.

Dzimwe nguva izvi zvinongokonzera shanduko diki pakurova kwemoyo wemwana (first-or-second-degree heart block). Izvi zvinogona kupera mushure mekuzvarwa. Zvisinei, vamwe vacheche vanogona kuva ne third-degree heart block, kana kuti complete heart block, nekuda kweNeonatal Lupus.

Apa ndipo apo masaini emagetsi anobva mumakamuri epamusoro emoyo asingakwanise kuenda kumakamuri epasi. Kana masaini aya akavharwa zvachose, moyo unorova zvisina kurongeka, zvichiita kuti zviomere moyo wemwana kupomba ropa rakakwana mumuviri. Kuvharika kwemoyo kwedhigirii rechitatu ndiko kwakanyanya kuipa. Dzimwe nguva kunogona kuuraya mwana asati aberekwa kana kuti mushure mekuzvarwa.

Kuvharika kwemoyo kunowanzoonekwa pakati pemavhiki gumi nemasere kusvika makumi maviri nemana epamuviri. Vanachiremba vanogona kuzviona panguva yekuzvitakura nekuteerera kurova kwemoyo kwemwana. Kana kurova kwemoyo kuchinonoka kupfuura zvaitarisirwa (kunonzi bradycardia), chingave chiratidzo chekuvhara kwemoyo.

Ndezvipi zvikonzero zveNeonatal Lupus?

Sezvatakambotaura, Lupus yeVacheche inokonzerwa nema antibodies anobva kuna amai kuenda kumwana kuburikidza ne placenta. Vaongorori vakabatanidza marudzi aya chaiwo ema antibodies neLupus yeVacheche:

• `(Anti-Sjögren's-syndrome-related antigen A (anti-SSA/Ro))`
• `(Anti-Sjögren's-syndrome-related antigen B (anti-SSB/La))`
• `(Anti-U1 ribonucleoprotein (anti-U1-RNP))`

Aya `(antibodies)` anowanikwa muvanhu vane zvirwere zvakasiyana-siyana zve autoimmune, zvakaita se`(Sjögren's syndrome)`,`(SLE)`,`(rheumatoid arthritis)` uye`(mixed connective tissue disease)`. Zvisinei, aya `(antibodies)` anogonawo kuwanikwa muvanhu vasina zviratidzo kana vasina kuonekwa vaine chirwere ichi.

Kana ma antibodies aya akapinda mumuviri wemwana, anogona kukonzera shanduko dzenguva pfupi kana dzechigarire. Vaongorori havasati vanyatsonzwisisa kuti ma antibodies aya anokonzera sei shanduko idzi. Asi vanoziva kuti shanduko dzakakomba uye dzechigarire ndedzemwoyo wemwana .

Kana zvangopinda mumoyo, ma antibodies aya anotanga kuzvimba, izvo zvinotungamira pakuumbwa kwemavanga. Mavanga aya anovhara masaini emagetsi, zvichitadzisa moyo wemwana kushanda zvakanaka. Muzviitiko zvakanyanya, izvi zvinogona kuva njodzi kuhutano panguva yekuzvitakura kana kukonzera matambudziko anotyisidzira hupenyu mushure mekusununguka.

Chirwere ichi chinonzi `(Neonatal Lupus)` chinoonekwa sei?

Vanachiremba vanoongorora Lupus yemwana achangoberekwa panguva yekuzvitakura kana kuti mushure mekusununguka. Kana vakaona kuti kurova kwemoyo wemwana kunonoka kupfuura zvaitarisirwa, vanozoita echocardiogram yemwana asati aberekwa. Iyi bvunzo yakachengeteka, isingarwadzi, uye isingapindi. Inogona kutarisa chimiro uye mashandiro emwoyo wemwana.

Iyi `(fetal echocardiogram)` inogona kuratidza shanduko dzinoratidza `(Neonatal Lupus)`. Kana zvakadaro, chiremba wako achakuudza nezvekukomba kwechirwere uye zvekutarisira mune ramangwana. Vachaongororawo ropa rako kuti rione kana paine `(antibodies) dzakakosha.`

Dzimwe nguva, zviratidzo zveNeonatal Lupus, zvakaita semaronda eganda, zvinongoonekwa chete mwana azvarwa. Kana izvi zvikaitika, timu yezvekurapa ichaita bvunzo yemuviri kuti ionekwe kuti hapana zvimwe zvinokonzera maronda. Vanogonawo kukuyedzai iwe, mwana wako, kana mese kuti muone ma antibodies ekubatsirai kuona chirwere ichi.

Chiremba wako achakuongorora kuti une chirwere cheNeonatal Lupus kana paine zvirwere izvi zviviri:

• Kana iwe ne/kana mwana wako muine `(positive)` ye `(anti-SSA)` uye/kana `(anti-SSB)` uye/kana `(anti-U1-RNP)`.

uye

• Kana mwana wako aine chiratidzo chimwe chete chakasimbiswa chekuti "Neonatal Lupus".

Lupus yemwana achangoberekwa inorapwa sei?

Kurapwa kunoenderana nekuoma kwechirwere. Hapana mushonga unodiwa pakukuvara kweganda, kuwanda kwemasero eropa, kana ma enzymes echiropa akawandisa. Matambudziko aya anowanzo pera ega mugore risingasviki.

Zvisinei, vacheche vanozvarwa vaine heart blockade vangangoda kuiswa pacemaker inochengetedza mwoyo panguva yekuzvarwa kana pahudiki. Uku kuvhiyiwa kunoitirwa kuti mwoyo wavo urove zvakanaka. Chikwata chevanachiremba vemwana wenyu chichakuudzai zvakawanda nezveizvi.

Imwe tsvakiridzo yakaratidza kuti kutora mimwe mishonga panguva yekuzvitakura kunogona kuderedza njodzi yekuti mwana wako aite heart blockade. Kana uine chirwere che autoimmune chakaonekwa, kana kuti ukaonekwa uine mamwe ma antibodies, chiremba wako anogona kukukurudzira kuti utore mushonga unonzi hydroxychloroquine panguva yekuzvitakura. Kuita izvi kunogona kubatsira kudzivirira mwana wako kubva kumatambudziko akaipisisa eNeonatal Lupus.

Chii chingave chiri fungidziro yevana vane Lupus yevana vacheche?

Maonero emwana wako anoenderana nekuti Lupus yemwana achangoberekwa inokanganisa sei muviri wake. Kune vacheche vane ganda, chiropa, uye/kana zvirwere zveropa chete, mamiriro acho akanaka kwazvo. Zvese zvinofanira kudzokera kune zvakajairika panosvika mwedzi 6 kusvika 9.

Zvisinei, kana mwoyo wavharika, mamiriro acho ezvinhu anogona kusiyana zvikuru. Dzimwe nguva mwoyo wavharika unogona kuuraya munhu asati aberekwa kana kuti mushure mekuzvarwa. Vana vazhinji vane mwoyo wavharika vanoda muchina unoshanda nguva dzose wekubatsira pacemaker panguva yehudiki.

Vana vadiki vane Lupus yeVacheche vanogona kuzova nechirwere che autoimmune chakadai seizvi:

• Arthritis yevana idiopathic
• Psoriasis
• Chirwere chethyroid chinozvirwisa mumuviri
• Chirwere cheshuga cherudzi rwekutanga

"Mwana wese akasiyana. Lupus yemwana achangoberekwa inogona kunge isina kana kukanganisa hupenyu hwemwana wako. Chikwata chavo chekurapa chichakupa rumwe ruzivo nezvezvaunotarisira uye magadzirirwo azvo."

Lupus yevana vacheche inogona kudzivirirwa here?

Hapana nzira yekumisa ma antibodies kuti asayambuke ne placenta paunenge uine pamuviri. Zvisinei, unogona kudzivirira kukuvara kwakanyanya kumoyo wemwana wako, kana kuronga pachine nguva chero kurapwa kupi zvako kungadiwa nemwana wako mushure mekuzvarwa. Kana ukaonekwa uine anti-SSA, anti-SSB, kana anti-U1-RNP, chiremba wako anogona kukurudzira zvinotevera:

• Kutora mimwe mishonga pakutanga kwekuzvitakura uye panguva yekuzvitakura kunogona kubatsira kudzivirira mwana kubva pakuva nechirwere chemwoyo chakavharika.
• Kuongororwa kwemoyo wakavharika (fetal echocardiograms) kubva pamavhiki angangoita gumi nematanhatu ekuzvitakura.
• Kutarisa mashandiro emwoyo wemwana mumwedzi wekutanga wehupenyu hwake. Izvi zvinoitirwa kutarisa zviratidzo zvemwoyo wakavharika (kana zvisati zvatoonekwa), sezvo vamwe vacheche vasingaratidzi zviratidzo kusvika mavhiki mashoma mushure mekuzvarwa.

Ndinofanira kutsvaga mazano ekurapa rini?

Zvakakosha kutevedzera purogiramu yekuongororwa uye yekusangana nemwana wako nemazvo. Vachakuudza kuti unofanira kuuya nemwana wako kangani kuti aongororwe uye atevererwe.

Zvakakoshawo kuchengetedza hutano hwako. Kana ukaonekwa uine mamwe ma antibodies asi usina zviratidzo zvechirwere che autoimmune, chiremba wako anogona kukutumira kuna rheumatologist, chiremba ane hunyanzvi mukurwadziwa kwemajoini nezvimwe zvirwere zvine chekuita nazvo. Izvi zvinodaro nekuti pane mukana wekuti unogona kutanga chirwere che autoimmune mumakore mashoma anotevera. Chiremba wako achakutsanangurira zvaunogona kutarisira uye achakutarisa zvakanyanya kuitira kuti ugone kurapwa nekukasika.

Mibvunzo ipi yandinofanira kubvunza chiremba wemwana wangu?

Mibvunzo iyi inogona kukubatsira kuti udzidze zvakawanda nezveNeonatal Lupus mushure mekuongororwa:

• Lupus yemwana achangoberekwa inokanganisa sei pamuviri pangu/mwana wangu?
• Ndezvipi zvingasarudzwa zvekurapa zviripo?
• Chii chinonzi fungidziro?
• Mikana ipi iripo yekuti Neonatal Lupus ichakanganisa pamuviri mune ramangwana?

Vanhu vakuru vanogona here kuwana chirwere che "Neonatal Lupus"?

Kwete, Lupus yeVacheche haisi chirwere chevanhu vakuru. Inoonekwa chete muvana vacheche nevacheche. Lupus yeVacheche haina kufanana nelupus yevakuru.

Systemic Lupus Erythematosus (SLE), yatinowanzodaidza kuti lupus, chirwere chinokonzerwa ne autoimmune chinokanganisa vana nevakuru. SLE ichirwere chinokanganisa muviri wese uye chinoda kurapwa nekutarisa hupenyu hwese.

Lupus yemwana achangoberekwa inongokanganisa mwedzi mishoma yekutanga yehupenyu hwemwana. Haikure pazera rekuva mudiki kana kuti pakukura.

Zvisinei, kunyangwe kana Neonatal Lupus ikasaonekwa kusvika mushure mekuzvarwa, inogona kuva nemigumisiro yenguva refu pamuviri wemunhu. Dambudziko guru ndiro heart block, iro rinogona kuda pacemaker yehupenyu hwese. Imwe tsvakurudzo inoratidza kuti vacheche vane Neonatal Lupus vanogona kunge vari panjodzi yakakura yekurwara nezvirwere zve autoimmune gare gare muhupenyu hwavo.

Kana wakambova neNeonatal Lupus uchiri mudiki, taura nachiremba wako kuti akuudze kuti ndeapi marudzi ekuongorora kana kuongororwa kwaungade paunenge uchikura.

Kana uine pamuviri wobva waongororwa seizvi, zvinogona kukuomera uye kushungurudza. Zvinogona kuoma kusaziva zvichaitika sezvo mimba yako iri kuramba ichikura. Hapana chakaipa nekuudza vanachiremba nezvekutya kwako. Vachaita zvese zvavanogona kuti vakubatsire kunzwisisa zviri kuitika uye zvaunogona kuita kuti uve nepamuviri pakanaka.

Kana mwana wako akaonekwa kuti ane chirwere ichi mushure mekuzvarwa, angangoda kutariswa mumwedzi wekutanga wehupenyu hwake kuti vaongorore mashandiro emwoyo wake. Vanogonawo kunge vaine maronda eganda anogara kwemwedzi yakati wandei. Chikwata chevanachiremba vemwana wako chichatsanangura zvaunofanira kutarisira uye chichakupa rutsigiro iwe nemhuri yese.

Zvinhu zvatinofanira kurangarira kubva munyaya iyi

Saka ngatitaurei nezve zvimwe zvezvinhu zvakakosha nezve Lupus yeVacheche Vachiri Kuyaruka zvatakataura nezvazvo:

• Lupus yemwana achangoberekwa chirwere chinoitika muvana vacheche nekuda kwema antibodies chaiwo anopfuudzwa kubva kuna amai kuenda kumwana.
• Izvi hazvina kufanana ne lupus (SLE) inoitika muvanhu vakuru.
• Kazhinji, zviratidzo zvacho ndezvenguva pfupi uye hazvikuvadzi, zvakaita semaronda eganda. Izvi zvinopora mukati memwedzi 6-9.
• Zvisinei, vamwe vacheche vanogona kuva nechirwere chakakomba chinonzi congenital heart block, icho chingada pacemaker.
• Kana amai vane chirwere chemuviri chinodzivirira muviri, kana kuti vane ma antibodies chaiwo (anti-SSA, anti-SSB), zvakakosha zvikuru kukurukura izvi nachiremba panguva yekuzvitakura.
• Vacheche vazhinji vanopora zvachose kubva mudambudziko iri. Kana matambudziko emwoyo akaitika, vanogona kurapwa.
• Kana muine mibvunzo kana kusava nechokwadi, musatya kubvunza chiremba. Varipo kuti vakubatsirei.

'Lupus yevana vacheche, vacheche vachangoberekwa, zvirwere zvevacheche, kuvharika kwemoyo, autoimmune immunity, ma antibodies emadzimai, mapundu eganda