Iwe kana mumwe munhu waunoziva pamwe muri kurapwa kenza. Munguva yekurapwa uku, kunyanya chemotherapy, masero ekenza anoparadzwa nekukurumidza. Kunyange zvazvo izvi zvakanaka, kana masero aya aparadzwa, zvinhu zviri mukati mawo, kunyanya kemikari inonzi uric acid , zvinoungana muropa rakawanda. Kuwedzera uku kamwe kamwe kwe uric acid hakuna kunaka kuitsvo dzedu. Saka, mumamiriro ezvinhu akadaro, vanachiremba vanoshandisa mushonga unonzi `Rasburicase`. Nhasi, ngatitaurei nezvemushonga uyu nemashoko akareruka.
Chii chinonzi Rasburicase iyi? Chii chaizvo chainoita?
Muchidimbu, Rasburicase (ರಾಸ್-ಬೀರೀ-ಕ್ಸ್) mushonga unodzora huwandu hweuric acid muropa redu. Unonyanya kushandiswa kuderedza nekudzivirira kuwedzera kamwe kamwe kwehuwandu hweuric acid mumuviri nekuda kwekurapwa kwegomarara.
Funga nezvetsinga dzedu dzeropa semugwagwa. Kana masero egomarara aparadzwa, uric acid inokonzera kufamba kwakawanda mumugwagwa uyu. Kufamba kwacho kunogona kukanganisa mashandiro enhengo inonyanya kukosha, itsvo. Mushonga wekuti `Rasburicase` unoshanda semupurisa wemumugwagwa, uchibvisa kuwanda kweuric acid mumuviri uye uchiishandura kuita imwe kemikari inogona kuburitswa nyore nyore mumuviri. Izvi zvinoita kuti kurapwa kwegomarara kurambe kuripo pasina kukuvadza itsvo.
Mushonga uyu unowanzo shandiswa semvura (infusion) inopinzwa mutsinga. Kureva kuti, inopinzwa mumuviri muhuwandu hushoma, semunyu. Inopinzwa muchipatara kana kiriniki pasi pekutarisirwa kwavanachiremba nevashandi vekurapa. `Elitek` izita rinozivikanwa remushonga uyu.
Zvinhu zvaunofanira kuudza chiremba wako usati watora mushonga uyu
Rasburicase mushonga une simba guru. Saka, zvakakosha kuzivisa chiremba wako nezvenhoroondo yako yehutano usati watanga kurapwa. Zvakakosha zvikuru kuvaudza kana uine chimwe chezvirwere zvinotevera:
| Mamiriro ehutano kana nhoroondo | Sei zvichikosha? (Tsananguro iri nyore) |
|---|---|
| Kushomeka kweG6PD | Ichi chirwere chemajini chinosanganisira enzyme iri mumasero eropa. Kana vanhu vane chirwere ichi vakapihwa Rasburicase, masero matsvuku eropa anogona kuparara uye kukonzera anemia yakanyanya. Saka izvi zvakakosha zvikuru . |
| Anemia kana nhoroondo yekupa ropa | Kana uchitova neanemia kana kuti wakambowedzerwa ropa kare, zvakakosha kuzivisa chiremba wako. |
| Kurwara kwakasiyana-siyana (Allergies) | Iva nechokwadi chekuudza chiremba wako kana uine allergies kune rasburicase, yeast, mannitol, mimwe mishonga, chikafu, kana madhayi. |
| Kubata pamuviri kana kuedza kubata pamuviri | Kana uine pamuviri kana kuti uchironga kubata pamuviri, zvakakosha zvikuru kuudza chiremba wako. |
| Kuyamwisa | Unofanira kurega kuyamwisa paunenge uchitora mushonga uyu uye kwemavhiki maviri mushure mekurega kuushandisa. Saka kana uri amai vanoyamwisa, udzawo chiremba wako nezvazvo. |
Zvinhu zvekungwarira pakushandisa mushonga uyu
Vashandi vezvehutano vachakutarisa zvakanyanya paunenge uchipihwa mushonga uyu.
- Kuongororwa kweropa: Panguva yekurapwa, uchafanirwa kuongororwa ropa nguva nenguva kuti utarise huwandu hwe uric acid yako, kuti mushonga wacho uri kushanda zvakanaka sei, uye kana paine zvimwe zvinokanganisa. Izvi zvakajairika, saka usazvidya mwoyo.
- Mimwe mishonga: Ipa chiremba wako runyoro rwakakwana rwemimwe mishonga, mavhitamini, mishonga yemiti, uye zvimwe zvinovaka muviri zvauri kutora. Mimwe mishonga inogona kukanganisa mushonga uyu.
- Kune vana: Mushonga uyu dzimwe nguva unopiwa vana vane mwedzi mumwe chete. Zvisinei, matanho akakosha anofanira kutevedzerwa. Kana uri kupa mwana wako mushonga uyu, taura nachiremba wevana nezvenyaya iyi.
Sezvo mushonga uyu uchipihwa muchipatara uchitarisirwa zvakananga navanachiremba nevanamukoti, haufanirwe kunetseka nezvekudarika mwero. Kana uchinzwa kusagadzikana chero kupi zvako, zivisa mukoti kana chiremba nekukasika. Vachatora matanho anodiwa pakuita izvozvo. Kana uchifungidzira kuti pane imwe chepfu, unogona kufonera National Poisons Information Centre kuColombo National Hospital kuti uwane mazano.
Ndezvipi zvimwe zvinogona kukonzera Rasburicase?
Kufanana nemushonga upi zvawo, `Rasburicase` inogona kukonzera migumisiro yakaipa kune vamwe vanhu. Zvisinei, havasi vese vanoiwana. Chinhu chakakosha ndechekutaura chero zviratidzo nekukurumidza.
| Kupatsanura migumisiro yakaipa | |
|---|---|
| Migumisiro yakaipa yaunofanira kuudza chiremba wako kana mukoti wako nekukasika | |
| Kusawirirana kwemuviri | Mapundu paganda, kuvaviwa, kuzvimba kwechiso, miromo kana rurimi. |
| Matambudziko ekufema | Kuoma kufema, kurwadziwa pachipfuva kana kusimba. |
| Matambudziko ekuyerera kweropa | Miromo kana nzara dzebhuruu, kurova kwemoyo nekukurumidza kana kusina kurongeka, kupera simba, BP yakaderera, maziso kana ganda kuita yero. |
| Zvimwe zviratidzo zvakakomba | Kubatwa nepfungwa, kuneta zvakanyanya kana kuneta, kuvhiringidzika. |
| Migumisiro isingawanzova yakakomba, asi inofanira kutaurwa kuna chiremba kana ikaramba iripo | |
| |
Rondedzero iyi haina migumisiro yese inogona kuitika, saka kana ukasangana nechimwe chinhu chisingawanzoitika, usatya kutaura nachiremba wako nezvazvo.
Mharidzo Yekuenda Nayo Kumba
- `Rasburicase` mushonga unopiwa kuchipatara kuderedza huwandu hweuric acid muropa hunowanda nekuda kwekurapwa kwegomarara.
- Usati watanga kurapwa, iva nechokwadi chekuudza chiremba wako nezvekushaya kwako G6PD, allergies, nezvimwe zvirwere zvese.
- Kuongororwa ropa nguva nenguva kwakakosha panguva yekurapwa.
- Zivisa chiremba wako kana mukoti wako nekukasika kana ukaona zviratidzo zvakakomba zvekurwara nepfungwa, zvakaita sekunetseka kufema, mapundu paganda, kana kuzvimba kumeso.
- Usayamwisa mwana zvachose paunenge uchitora mushonga uyu uye kwemavhiki maviri mushure mekurega.
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