Ko thyroid yako inoita kunge ichiita zvinhu zvakawandisa here? Ngatitaurei nezve Subclinical Hyperthyroidism!

Chiremba wako akati huwandu hweTSH yako hwakaderera zvishoma pakuongororwa ropa nguva pfupi yadarika here? Kana kuti une zviratidzo zvisinganzwisisike, zvakaoma kunzwisisa here? Ungave uine chirwere chinonzi Subclinical Hyperthyroidism. Usazvidya mwoyo, kazhinji hachisi chakakomba. Ngatitaurei nezvazvo zviri nyore uye zvakajeka.

Chii chinonzi subclinical hyperthyroidism?

Zvichitaurwa zviri nyore, `Subclinical Hyperthyroidism` chirwere apo thyroid gland yako iri kushanda zvishoma kupfuura zvakajairika. Asi haina kunyanya kuipa se `overt hyperthyroidism` .

Gland repituitary riri muuropi hwedu rinoburitsa hormone inonzi `TSH` (Thyroid-Stimulating Hormone). Iyi `TSH` inoudza thyroid gland iri mumutsipa wedu kuti igadzire mahormone maviri anonzi thyroxine (`T4` - `thyroxine`) uye triiodothyronine (`T3` - `triiodothyronine`). Aya mahormone e`T3` ​​uye `T4` ndiwo anobatsira metabolism yemuviri wedu, kureva kuti, kushandura chikafu chatinodya kuita simba uye kurishandisa mumuviri wedu.

Mu `Subclinical Hyperthyroidism`, `TSH` yeropa rako yakaderera, asi `T3` ​​​​uye `T4` mazinga ako akajairika. Izvi zvinoreva kuti thyroid iri kushanda zvakanyanya, saka pituitary gland inoti, "Zvakanaka, handidi `TSH` izvozvi, thyroid yangu iri kushanda zvakanaka," uye inoderedza kugadzirwa kwe`TSH`. Asi mahormone ethyroid (`T3`, `T4`) haasati akwira zvakanyanya. Ndizvo zvinoreva `subclinical` - chirwere chiri pasi pechirwere chisingaratidze zviratidzo zviri pachena.

Dambudziko iri dzimwe nguva rinogona kuva renguva pfupi , zvichireva kuti rinogona kunaya roga mumazuva mashoma. Zvisinei, kune vamwe vanhu rinogona kugara risingaperi. Havasi vese vanoda kurapwa.

Ndiani anonyanya kubatwa nechirwere ichi?

Munhu wese anogona kuwana `Subclinical Hyperthyroidism`, asi vanhu vanotevera vari panjodzi yakakura zvishoma:

• Vanhu vari kutora mushonga wekutsiva mahormone ethyroid (semuenzaniso, levothyroxine) wekuti vabatwe ne hypothyroidism. Dzimwe nguva izvi zvinogona kuitika kana mushonga wacho ukawedzerwa zvishoma.
• Kune avo vane makore anopfuura makumi matanhatu nemashanu ekuberekwa.

Dambudziko iri rakajairika zvakadii?

Izvi hazviwanzoitika munyika dzakadai seAmerica.

Vanhu vanosvika 0.7% vane `Subclinical Hyperthyroidism`, uko mazinga eTSH ari pasi pe0.1 mIU/L. Vamwe 1.8% vane mazinga e`TSH` ari pasi pe0.4 mIU/L.

Zvisinei, munyika dzine kushomeka kweiodine , kunyanya pakati pevanhu vane makore anopfuura makumi manomwe, chirwere ichi chinogona kusvika pa15%. MuSri Lanka, njodzi iyi yakaderera nekuti tinowanzo shandisa munyu une iodine , asi zvakanaka kuziva.

Zviratidzo zvacho ndezvipi?

Kazhinji, vanhu vane `Subclinical Hyperthyroidism` havaratidzi zviratidzo . Ndosaka ichinzi "subclinical".

Zvisinei, dzimwe nguva unogona kuona zviratidzo zvisina kusimba zvine chekuita ne hyperthyroidism. Panguva dzakadaro, unogona kusangana nezvinhu zvakaita se:

• Kunzwa sekuti moyo wako uri kurova nekukurumidza (kurova kwemoyo).
• Zvinoita sekuti muviri wangu uri kudedera, ndichingonzwa kutya.
• Kuderedza huremu (pasinei nekudya).
• Kudya kwakawedzera.
• Manyoka kana kufamba-famba uchibuda ura kakawanda.
• Ganda rinoita serakatetepa, rinodziya, uye rakanyorova.
• Kuchinja kwekufamba kwemwedzi kwevakadzi (`Kuchinja kwemwedzi`).

Zvakakosha: Kuva nezviratidzo izvi hazvirevi hazvo kuti une `Subclinical Hyperthyroidism`. Zvisinei, kana zviratidzo izvi zvikaramba zviripo, kuchenjera kuona chiremba.

Sei izvi zvichiitika? Ndezvipi zvikonzero?

Kazhinji, sisitimu yedu ye endocrine inoshanda pamwe chete. Funga nezvazvo sekambani hombe.

Hypothalamus, iri pasi pehuropi, inoburitsa hormone inonzi TRH (Thyroid-Releasing Hormone). Izvi zvinoudza pituitary gland kuti igadzire TSH.

Zvadaro `TSH` inoenda youdza thyroid gland kuti igadzire `T3` ​​​​(inenge 20%) uye `T4` (inenge 80%). Kana `T3` ​​​​uye `T4` izvi zvikawedzera muropa, zvinotumira zvakare chiratidzo ku pituitary gland ichiti, "Zvakanaka, rega kugadzira `TSH` izvozvi, pane hormone yakakwana." Izvi zvinonzi ` feedback loop` . Kana `T3` ​​uye `T4` zvikadzikira, kutenderera uku kunotanga zvakare kubva pakutanga.

Zvisinei, mu `Subclinical Hyperthyroidism`, nekuda kwechimwe dambudziko mugland re thyroid, kunyangwe huwandu hwe`TSH` hwakaderera, kugadzirwa kwemahormone e thyroid hakuderedzi sezvaitarisirwa. Ndosaka `TSH` yakaderera, asi `T3` ​​​​uye `T4` zviri pamazinga akajairika.

Zvikonzero zve "Subclinical Hyperthyroidism" zvakafanana zvikuru nezvinokonzera hyperthyroidism inoonekwa pachena. Heano mamwe ezvikonzero zvikuru:

• Kuwedzera mushonga wehomoni (levothyroxine) unopihwa kune hypothyroidism (thyroid isingashande zvakanaka). Ichi ndicho chikonzero chinowanzoitika.
• Goiter ine chepfu yakawanda. Ichi chirwere apo mapundu (nodules) asiri ekenza anokura mugland regland, zvichiita kuti rigadzire mahomoni egland akawandisa.
• Chirwere cheGraves. Ichi chirwere chinokonzerwa ne autoimmune. Izvi zvinoreva kuti masoja emuviri wedu anorwisa thyroid gland, zvichiita kuti igadzire mahormone akawanda.
• Thyroiditis: Kana thyroid gland ikazvimba, huwandu hwemahormone hunogona kuwedzera kwenguva pfupi.

Unozviziva sei izvi?

Kuongororwa kwebasa re thyroid ndiyo chete nzira yekuziva zvechokwadi kana uine `Subclinical Hyperthyroidism` kana kuti kwete.(Kuongororwa kwebasa re thyroid chete. Izvi zvinoitwa nguva dzose pakuongororwa ropa.

Huwandu hweTSH (inonziwo thyrotropin) mumunhu mukuru asina pamuviri huri pakati pe0.4 ne4.5 milli-international units per litre (mIU/L).

Kana bvunzo dzeropa rako dzichiratidza kuti TSH yako yakaderera (pakati pe0.1 ne0.4 mIU/L kana pasi pe0.1 mIU/L), asi mazinga ako eT4 (thyroxine) neT3 (triiodothyronine) ari mukati mehuwandu hwakajairwa, une Subclinical Hyperthyroidism.

`Subclinical Hyperthyroidism` inogona kukamurwa kuita mapoka maviri makuru:

• Zvishoma: Mazinga eTSH akaderera, asi achiri kuonekwa - kazhinji ari pakati pe0.1 ne0.4 mIU/L. Aya mazinga aripo mu65% kusvika 75% yevanhu vane Subclinical Hyperthyroidism.
• Zvakanyanya: Mazinga eTSH ari pasi pe0.1 mIU/L. Izvi zvinokanganisa pakati pe25% ne35% yevanhu.

Izvi zvinoda kurapwa here?

Kune maonero akasiyana pakati pevanachiremba pamusoro pekurapa `Subclinical Hyperthyroidism` kana kuti kwete, nekuti hapasati pave netsvakiridzo yakakwana pamusoro pemabhenefiti akajeka ekurapa.

Vanachiremba vanowanzokurudzira vanhu vane subclinical hyperthyroidism kuti vaone nzira yekuti "mirai muone" . Kureva kuti, vanomirira kuti mamiriro acho ega agadzirisike vasina kutanga kurapwa.

Zvisinei, kurapwa kunogona kukurudzirwa kune avo vane mazinga eTSH ari pasi pe0.1 mIU/L nguva dzose, kunyanya mune zvinotevera:

• Kana une makore makumi matanhatu nemashanu zvichikwira.
• Kana uri pasi pemakore makumi matanhatu nemashanu ekuberekwa, uine chirwere chemwoyo, osteoporosis, kana zviratidzo zvehyperthyroidism.
• Kana uri mukadzi apedza kuenda kumwedzi, uri pasi pemakore makumi matanhatu nemashanu, uye usingatore estrogen kana bisphosphonates (rudzi rwemushonga unoshandiswa kurapa matambudziko emapfupa).

Subclinical hyperthyroidism panguva yekuzvitakura kazhinji haidi kurapwa.

Kana kurapwa kwacho kuchiitwa, chii ichocho?

Kana chiremba wako akasarudza kuti kurapwa kwakakosha, kurapwa kwacho kunoenderana nechikonzero che subclinical hyperthyroidism.

• Kana uine goiter ine chepfu ine ma "multinodular goiter" (bundu riri mumutsipa) kana "bundu" rimwe chete pa "thyroid", mushonga unonyanya kushandiswa i "radioactive iodine" . Uyu mushonga waunonwa nemuromo. Masero anoshanda zvakanyanya mu "thyroid" yako anonwisa iodine. Iyo iodine ine radioactive inokuvadza masero iwayo, zvichiita kuti thyroid iderere uye huwandu hwemahormone ako hudzike mukati memavhiki mashoma.
• Kana uine chirwere cheGraves, mishonga inonyanya kushandiswa ndeyemishonga inorwisa thyroid uye iodine ine radioactive. Mishonga inorwisa thyroid yakaita semethimazole (Tapazole) uye propylthiouracil (PTU) inoshanda nekudzivirira kugona kwegland re thyroid kugadzira mahormone.

Izvi zvinogona kudzivirirwa kuti zvisaitike here?

Kazhinji, hapana chatingaita kudzivirira kukura kwe `Subclinical Hyperthyroidism` kana `Hyperthyroidism` inoonekwa pachena.

Zvisinei, kana usingawani iodine yakakwana mukudya kwako (kana kuti yakawandisa) , unogona kuva ne 'Subclinical' kana 'Overt Hyperthyroidism' nekuda kwe 'toxic goiter'. Kunyangwe izvi zvisingawanzoitika munyika dzakadai seSri Lanka nekuti tinoshandisa munyu une iodized, zvinogona kuonekwa munyika dzine kushomeka kwe iodine.

Chii chatingatarisira nechirwere ichi? Pane njodzi here?

Subclinical hyperthyroidism haiwanzo kufambira mberi kusvika pakuva hyperthyroidism inooneka. Zvisinei, njodzi iyi yakakwira zvishoma kune vanhu vane mazinga eTSH akaderera (ari pasi pe0.1 mIU/L).

Nekuti kune zvikonzero zvakawanda, `Subclinical Hyperthyroidism` yemunhu wese yakasiyana.

Kunyangwe zvikasafambira mberi kusvika pakuva `Overt Hyperthyroidism`, `Subclinical Hyperthyroidism` inogona kukonzera mamwe matambudziko. Mamwe acho ndeaya:

• Kurova kwemoyo zvisina kurongeka (atrial fibrillation ).
• Kukundikana kwemoyo (njodzi yekukundikana kwemoyo ).
• Chirwere chemwoyo (chirwere chemwoyo ).
• Kurasikirwa nemapfupa uye kutyoka.
• Dementia ( chirwere chekurasikirwa nendangariro chinogona kuitika nekukura).

Njodzi idzi dzakanyanya kukwira kuvanhu vane makore anopfuura makumi matanhatu nemashanu uye avo vane chirwere chegomarara remudumbu (subclinical hyperthyroidism).

Kana uchinetseka nezvenjodzi idzi, zvakanaka kutaura nachiremba wako nezvazvo.

Ndinofanira kuona chiremba rini?

Kazhinji, kana bvunzo dzako dzichiratidza kuti une "Subclinical Hyperthyroidism," vanachiremba vanotora nzira yekuti "mira uone".

Zvisinei, kana ukatanga kuona zviratidzo zvehyperthyroidism (kuzvidya mwoyo, kusagadzikana, kurova kwemoyo), iva nechokwadi chekuona chiremba wako. Iye achaita imwe bvunzo yeropa rethyroid kuti aone kana uine `Overt Hyperthyroidism`.

Yeukai, kuchine maonero akasiyana-siyana pamusoro pekurapa `Subclinical Hyperthyroidism` kana kuti kwete. Munhu wese, mamiriro ese ezvinhu akasiyana. Saka, chinhu chakanakisa chekuita ndechekukurukura mibvunzo yako yese nezvaunotya nachiremba wako. Iye akagadzirira uye anoda kukubatsira.

Mharidzo Yekuenda Nayo Kumba

Zvakanaka, saka hezvino zvimwe zvinhu zvaunofanira kuyeuka kubva pane zvatataura nezvazvo:

• "Subclinical Hyperthyroidism" chirwere apo thyroid gland inongova nekushanda kwakawandisa zvishoma, asi isingaratidze zviratidzo zvikuru.
• Izvi zvinoonekwa nekuongororwa kweropa kunoratidza mazinga eTSH akaderera (asi T3 neT4 zvakajairika).
• Sezvo kazhinji pasina zviratidzo, kurapwa kungasave kwakakosha. Chiremba wako anogona kutora nzira yekuti "mira uone".
• Vamwe vanhu, kunyanya vakwegura kana avo vane mamwe matambudziko ehutano, vangada kurapwa.
• Kana ukaona zviratidzo zvehyperthyroidism (zvakadai sekurova kwemoyo zvakanyanya, kudedera, kudzikira kwehuremu), enda kuna chiremba nekukasika.
• Chinhu chinonyanya kukosha kusatya, kutaura pachena nezvazvo nachiremba wako, uye kutevedzera mazano ake.

Ndinovimba kuti ruzivo urwu runobatsira. Ramba uine hutano hwakanaka!

` Subclinical Hyperthyroidism, thyroid, TSH, T3, T4, mahormone, chirwere cheGraves, goiter