Unewo kurwadziwa kwemudumbu kusingarapiki here? Ngatidzidzei nezve bundu reVIPoma (Vasoactive Intestinal Peptide Secreting)!

Dzimwe nguva unonzwa manyoka akanyanya anotora mazuva, achiperekedzwa nekurwadziwa mudumbu uye kurwadziwa kwemudumbu here? Ungave usingadyi kana kunwa chero chinhu, asi uchiri kunzwa saizvozvo. Kana uine zviratidzo zvakaita seizvi, chikonzero chingave chisingawanzoitiki, asi chingave chirwere chatinofanira kutaura nezvacho. Nhasi tiri kutaura nezvechimwe chirwere chakadai chinonzi VIPoma , kana kuti `Vasoactive Intestinal Peptide Secreting` tumor . Kunyangwe zita racho ringanzwika serakaoma, ngatirambei tichiri nyore.

Chii chinonzi bundu reVIPoma?

Zvichitaurwa zviri nyore, VIPoma ibundu risingawanzoitiki rinokura mupancreas . Zvikuru sei, aya mabundu anokura mumasero anogadzira mahormone epancreas, anonzi endocrine cells . Dzimwe nguva vanachiremba vanodana chirwere ichi kuti `Verner-Morrison syndrome` .

Matumbu eVIPoma haawanzoitiki . Kunyangwe munyika yakaita seAmerica, chirwere ichi chinonzi chinoitika muvanhu vanosvika mamiriyoni gumi. Saka unogona kufungidzira kuti hachiwanzoitiki sei. Kurarama nechirwere chisingawanzoitiki kudaro kunogona kuva dambudziko guru, nekuti chine simba guru pahupenyu hwako hwezuva nezuva. Asi, usazvidya mwoyo . Iye zvino kune mishonga inogona dzimwe nguva kurapa chirwere ichi cheVIPoma zvachose, kana kudzora zviratidzo zvacho.

Ndezvipi zviratidzo zvegomarara reVIPoma?

Chiratidzo chikuru uye chinonyanya kukosha chinoonekwa pachirwere ichi manyoka akasimba, ane mvura . Izvi zvakanyanya zvekuti unogona kuva nemanyoka aya kunyangwe usiri kudya (kutsanya). Haaperi mumazuva mashoma. Ichi ndicho chiratidzo chinonyanya kuzivikanwa chechirwere ichi.

Kunze kweizvozvo, panogona kunge paine zvimwe zviratidzo zvakawanda:

• Kurwadziwa kwemudumbu: Dumbu rako rinogona kunzwa sekunge riri kutenderera kana kuti rinogona kurwadza kubata.
• Kuneta: Kunzwa kuneta uye kusararama nguva dzese.
• Kusviba: Kutsvuka kamwe kamwe kwechiso nechipfuva. Izvi zvinogona kuitika pasina chikonzero chakajeka.
• Kushaya simba kwetsandanyama: Unganzwa sekunge makumbo ako ari kupera simba, uye zvingave zvakaoma kusimudza zvinorema.

Fungidzira kuti waizonzwa sei kudai waizopa mabhodhoro maviri kana matatu emvura sechituru pazuva. Izvi zvinogona kuoma zvekuti haugone kuita mabasa ako ezuva nezuva.

Chii chinokonzera kuti VIPoma ibude?

Nyanzvi hadzisati dzaziva kuti chii chinokonzera bundu reVIPoma, asi dzine ruzivo rwakajeka rwekuti zviratidzo izvi zvinoitika sei.

Muviri wedu une hormone inonzi `Vasoactive Intestinal Peptide` (VIP) . Iyi hormone yeVIP ndiyo inotungamira mukugadzirisa kugaya kwedu.Zvinobatsira zvikuru. Kureva kuti, homoni iyi inodzora kuburitswa kwemvura, munyu, maenzyme, uye acid yemudumbu mudumbu. Inobatsirawo kuzorodza dzimwe tsandanyama dziri mudumbu.

Kana bundu reVIPoma rikabuda, rinoburitsa huwandu hwakawanda hwehomoni yeVIP mumuviri. Kana homoni iyi yeVIP yakawandisa ikapinzwa mumuviri, zviratidzo zvambotaurwa, zvakaita semanyoka akanyanya uye kurwadziwa mudumbu, zvinoitika. Zvichitaurwa zviri nyore, bundu iri rinoita kuti homoni yeVIP ishande zvakanyanya.

Ndezvipi zvinetso zvinogona kuitika nekuda kweVIPoma?

Dambudziko guru reVIPoma manyoka akawandisa. Vamwe vanhu vanogona kunwa tsvina ine mvura inosvika litre imwe kusvika matatu (1-3 litres) pazuva. Kana manyoka aya akaramba achiitika, muviri unorasikirwa nemvura yakawanda uye maminerari akakosha, kunyanya potassium.

Izvi zvinogona kukonzera kupera mvura mumuviri uye kushaya kanganisika kweropa nekufamba kwenguva. Zvese izvi zvine njodzi nekuti zvinogona kukonzera matambudziko makuru ehutano. Semuenzaniso:

• Kusarongeka kwekurova kwemoyo (`Arrhythmia`): Kusarongeka kwemoyo.
• Kuvhunduka kweHypovolemic: Chirwere chinokonzerwa nekudzikira kwehuwandu hwemvura mumuviri.
• Kushaya simba kwetsandanyama (`Myopathy`): Kusashanda zvakanaka kwetsandanyama.
• Tetany: Kurwadziwa kwetsandanyama.

Nekuda kwezvinetso izvi, zvakakosha zvikuru kutsvaga rubatsiro rwechiremba nekukasika kana uine zviratidzo zveVIPoma.

Vanachiremba vanoongorora sei VIPoma?

Kana uine zviratidzo zvakaita semanyoka akanyanya kana kurwadziwa mudumbu kwagara kuripo kwemazuva akati wandei, chiremba achakuongorora muviri wako obvunza nezvezviratidzo zvako.

Kuongororwa kwetsvina kunogona kuitwawo kuti pasave nezvimwe zvirwere zvinowanzo kukonzera manyoka (semuenzaniso, hutachiona). Pamusoro pezvo, bvunzo dzinotevera dzinogona kuitwa:

• Kuongororwa kweropa: Izvi zvinonyanya kuongorora huwandu hwehomoni yeVIP muropa. MuVIPoma, huwandu uhwu hwakakwira zvikuru. Vanogonawo kuongorora zvinhu zvakaita sekushaya mvura mumuviri uye kushomeka kwepotassium.
• Kuongororwa kwemifananidzo: Izvi zvinotora mifananidzo yemukati memuviri kuti zvionekwe kana paine bundu, kana riripo, kuti riri kupi, uye kuti rakakura sei. Izvi zvinogona kusanganisira `Computed Tomography (CT) scan` kana `Magnetic Resonance Imaging (MRI)` bvunzo .

Vanachiremba vanosimbisa mamiriro eVIPoma mushure mekuita bvunzo idzi dzese.

VIPoma inorapwa sei?

Kurapa VIPoma kunowanzosanganisira musanganiswa wemishonga nekuvhiyiwa. Chiremba wako anogona kukurudzira zvinotevera:

• Mvura inopinzwa mutsinga (`mvura yemutsinga`):Izvi zvinopihwa kutsiva mvura nemaminerari anorasika mumuviri nekuda kwemanyoka anoramba achiitika. Izvi zvinogona kubatsira kudzora kushaya mvura mumuviri.
• Mishonga:
• Manyoka anogona kudzorwa nemishonga yakaita se "Octreotide (Sandostatin LAR®)" . Mishonga iyi inoderedza kuburitswa kwehomoni inonzi VIP.

Mushure mekutanga kugadzirisa zviratidzo zvako nenzira iyi, chiremba wako anogona kukupa mamwe marapirwo ekubvisa kana kudzora bundu racho:

• Kuvhiyiwa: Kana bundu risina kupararira kune dzimwe nhengo dzemuviri (rakaita metastasized) , kuvhiyiwa kunogona kushandiswa kubvisa bundu. Izvi zvinogona kuitwa nekuvhiyiwa kunonzi distal pancreatectomy, kunobvisa muswe nemuviri wepancreas. Kana bundu rikabviswa zvachose, chirwere chinogona kurapwa.
• Kurapa nemakemikari: Kana bundu racho rapararira kana kuti risingabviswi zvachose nekuvhiyiwa, chemotherapy inopihwa kuti iparadze masero ekenza.
• Kurapa kwakanangana: Iyi mishonga inorwisa zvikamu zvemasero ekenza.

Chikwata chenyu chezvekurapa chichasarudza marapirwo akakodzera kwamuri mushure mekunyatsoongorora mamiriro enyu.

Chii chingatarisirwa nemunhu ane VIPoma?

Izvi zvinosiyana-siyana kubva pamunhu kusvika pamunhu. Kuvhiyiwa kunogona kurapa VIPoma zvachose. Mishonga inogona kudzora zviratidzo zvakanyanya.

Zvisinei, mamiriro ezvinhu emunhu wese akafanana . Zvawakasangana nazvo zvinogona kusiyana zvikuru nezvakaitika kune mumwe munhu neVIPoma. Chiremba wako wepachipatara nechikwata chekurapa ndivo vanhu vakanakisisa kukupa ruzivo nekutungamira. Vanokuziva zvakanyanya iwe nemamiriro ako ezvinhu, saka vabvunze chero chaunoda kuziva.

Ndinofanira kuona chiremba rini?

Kana uri kutogamuchira kurapwa kweVIPoma, fonera chiremba wako nekukasika kana zviratidzo zvako zvikasavandudzika kana kuti zvikasawedzera kuipa.

Uyewo, enda kuchipatara kana uine chimwe chezviratidzo izvi:

• Kana muine kurwadziwa kwakanyanya mudumbu .
• Kana wave nechirwere chemanyoka chinoyerera nemvura kwemazuva akati wandei .
• Kana uri kuratidza zviratidzo zvekupererwa nemvura mumuviri , zvakaita sekunge uchinzwa musoro wakareruka, kunzwa dzungu, kana kuva neweti yero yakasviba kana yebrown.

Manyoka asingarapiki anokonzerwa neVIPoma anogona kukanganisa mabasa ako ezuva nezuva uye kunyange kurara kwako husiku. Kuziva chinokonzera zviratidzo izvi kunogona kukubatsira. Zvisinei, nekuti VIPoma chirwere chisingawanzoitiki, vanhu vashoma vanoziva nezvacho. Izvi zvinogona kuita kuti unzwe kusurukirwa uye kusuruvara. Ungatonzwa kunyara nezvezviratidzo zveVIPoma.

Chikwata chenyu chezvekurapa chinonzwisisa manzwiro aya zvakanaka, saka musazeza kuvakumbira rubatsiro rwamunoda, kungave kuri pakugadzirisa zviratidzo zvenyu kana kurarama nechirwere chisingawanzoitiki.

Zvinhu zvakakosha zvatinofanira kurangarira (Mharidzo Yekuenda Kumba)

VIPoma ibundu risingawanzoitiki rinokura mupancreas. Rinokonzera kuburitswa kwakanyanya kwehomoni inonzi VIP, iyo inokonzera zviratidzo zvakaita semanyoka akanyanya uye kurwadziwa mudumbu. Kana zviratidzo izvi zvikaramba zviripo, zvakakosha kutsvaga rubatsiro rwechiremba. Kurapwa nekukurumidza kwakakosha sezvo matambudziko akadai sekushaya mvura mumuviri uye kushomeka kwepotassium mumuviri anogona kuitika. Kune marapirwo akadai sekuvhiyiwa, mishonga, uye chemotherapy. Kunyangwe ichi chirwere chisingawanzoitiki, hausi wega. Tsvaga rutsigiro kubva kuchikwata chako chekurapa.

VIPoma , Vasoactive Intestinal Peptide, Pancreatic Cancer, Manyoka, Verner-Morrison syndrome, Hormonal Imbalances, Rare Diseases