Usenokuba ukhathazekile kancinci xa ubona ixabiso eliphezulu elinoonobumba abathathu be-GGT kwingxelo yakho yegazi. Usenokuba uzibuza, "Yintoni le GGT? Kutheni iphezulu kangaka?" Ungakhathazeki. Namhlanje, siza kuthetha ngokuba yintoni le GGT, kutheni kwenziwa olu vavanyo, kunye nokuba ixabiso eliphakamileyo lithetha ukuthini ngokwenene.
Yintoni iGGT?
Ngamafutshane, i-GGT, emele iGamma-Glutamyl Transferase, luhlobo lwe-enzyme emzimbeni wethu. I-enzyme yinto enceda kwiinkqubo zeekhemikhali emzimbeni wethu. Le enzyme ye-GGT ifumaneka kakhulu kwisibindi sethu. Nangona kunjalo, inokufumaneka ngobuninzi obuncinci nakwezinye iindawo zomzimba ngaphandle kwesibindi.
Umsebenzi wayo ophambili kukukhusela iiseli emzimbeni wethu ekonakalisweni. Cinga nge-GGT njengabalindi abancinci abakhusela iiseli zethu. Xa iiseli ziqala ukonakala ndaweni ithile, aba balindi beza bebaleka ukuze bazikhusele. Ngoko ke, ukunyuka kwenqanaba le-GGT egazini kuthetha ukuba kukho umonakalo ndaweni ithile emzimbeni, kwaye i-enzyme ye-GGT isebenza nzima kakhulu ukulwa nayo.
Yintoni uvavanyo lwegazi lweGGT?
Olu luvavanyo oluqhelekileyo oluthatha isampuli encinci yegazi engalweni yakho. Ugqirha wakho uza kuyalela olu vavanyo ikakhulu ukujonga umonakalo wesibindi okanye ukuba ukrokrela ukuba kukho ukuvaleka kwimibhobho yenyongo yakho . Olu vavanyo lulinganisa ubungakanani be-enzyme ye-GGT egazini lakho.
Amanqanaba aphezulu e-GGT anokubonisa iimeko ezininzi zempilo ezichaphazela isibindi, intliziyo, okanye amanye amalungu omzimba. Ukusetyenziswa kotywala kunye namayeza athile kunokubangela ukunyuka kwamanqanaba e-GGT.
Kodwa eyona nto ibalulekileyo kukuba awunakukwazi ukufumanisa nasiphi na isifo ngokujonga ixabiso lengxelo ye-GGT yodwa. Oogqirha bahlala besebenzisa olu vavanyo lwe-GGT kunye nezinye iimvavanyo ezininzi ezijonga ukusebenza kwesibindi.
Olu vavanyo lwe-GGT lubizwa nangamanye amagama aliqela:
- I-Gamma-glutamyl transpeptidase
- I-GGTP
- I-Gamma-GT
- I-GTP
Kutheni ugqirha ekuxelela ukuba wenze uvavanyo lwe-GGT?
Kusenokuba kukho izizathu ezininzi eziphambili zokuba ugqirha wakho angayalela olu vavanyo.
Ukuba uneempawu zesibindi
Ukuba ufumana iimpawu zesifo sesibindi, ugqirha wakho ngokuqinisekileyo uya kukucebisa olu vavanyo.
- Ukutyheli kolusu (i-jaundice)
- Intlungu kwicala eliphezulu lasekunene lesisu
- Isicaphucaphu nokuhlanza
- Ndiziva ndidiniwe kakhulu
- Umnqweno wokutya
Kwiimeko ezinjalo, kungekuphela nje uvavanyo lwe-GGT, kodwa nezinye iimvavanyo ezininzi ezilinganisa ukusebenza kwesibindi nazo zenziwa. Ezi zivavanyo ze-`ALT (Alanine Transaminase)`, `AST (Aspartate Aminotransferase)`, `ALP (Alkaline Phosphatase)` kunye ne-`Bilirubin`. Kuphela xa zonke ezi ngxelo zidibana apho umfanekiso opheleleyo unokwenziwa khona.
Ukuba ixabiso lakho le-ALP liphezulu
Khawuthelekelele ukuba ixabiso le-`ALP (Alkaline Phosphatase)` kuphela elikwingxelo yegazi lakho liphakanyisiwe. Kunokubakho izizathu ezibini zokuba ixabiso le-ALP linyuke. Esinye yingxaki yesibindi okanye imibhobho yenyongo. Esinye yingxaki ngamathambo (amathambo).
Ngoku ugqirha ufuna ukwazi ukuba ingaba imbangela sisibindi okanye amathambo. Kulapho uvavanyo lwe-GGT luluncedo kakhulu khona.
- Ukuba amanqanaba akho e-ALP kunye ne-GGT aphakanyisiwe , unobangela kusenokwenzeka ukuba yingxaki yesibindi okanye ye-bile duct.
- Ukuba inqanaba lakho le-ALP liphezulu kwaye inqanaba lakho le-GGT liqhelekile , unobangela mhlawumbi yingxaki enxulumene namathambo.
Uyaqonda na ukuba olu vavanyo lubaluleke kangakanani?
Ukuba kukho nakuphi na ukurhanelwa kokusetyenziswa kotywala
Uvavanyo lwe-GGT lusetyenziselwa ukuchonga abantu abasela kakhulu utywala kunye nokujonga imeko yabo ngexesha lonyango. Xa ukusela utywala konakalisa isibindi (i-alcoholic hepatitis), ixabiso le-GGT linyuka kakhulu.
Ngaba kufuneka ndilungiselele ngaphambi kovavanyo lwe-GGT?
Ewe, kufuneka ulungiselele kancinci ngaphambi kokuba wenze olu vavanyo.
- Xelela ugqirha wakho ngamayeza owasebenzisayo: Amanye amayeza owasebenzisayo anokuchaphazela amanqanaba akho e-GGT. Ngoko ke, xelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka iivithamini kunye namayeza esintu. Ungaze uyeke ukuthatha naliphi na iyeza ngaphandle kokuba ugqirha wakho ekuxelele ukuba wenjenjalo.
- Ziphephe utywala: Musa ukusela naluphi na uhlobo lotywala ubuncinane iiyure ezingama-24 ngaphambi kovavanyo. Nokuba sisixa esincinci sotywala sinokunyusa amanqanaba akho e-GGT, nto leyo enokwenza ingxelo ingachaneki.
Kwenzeka ntoni ngexesha lovavanyo?
Le yinkqubo elula kakhulu.
1. Uza kuhlaliswa esitulweni, kwaye umongikazi okanye ingcali yezonyango iza kukhetha umthambo olungileyo engalweni yakho (ngesiqhelo ngaphakathi kwengqiniba yakho).
2. Coca indawo nge-cotton swab.
3. Emva koko kufakwa inaliti encinci emthanjeni kwaye igazi elithile litsalwa kwityhubhu. Ngeli xesha, uya kuziva uvakalelwa kancinci, njengokulunywa imbovane.
4. Emva kokuba igazi litsaliwe, inaliti iyasuswa, iqhekeza lekotoni libekwe kuloo ndawo lize licinezelwe. Emva koko kufakwa iplasta encinci.
Lonke eli xesha lithatha ngaphantsi kwemizuzu emihlanu.
Lifanele libe yintoni ixabiso eliqhelekileyo lengxelo yeGGT?
Ngokwesiqhelo, ixabiso le-GGT kufuneka libe ngaphantsi kwe-50 U/L (iiyunithi ngelitha). Nangona kunjalo, oku kunokwahluka kancinci kwilabhoratri nganye. Ke ngoko, kungcono ukuthelekisa ixabiso lakho nexabiso elichazwe kwingxelo yakho njenge-'Normal Range' okanye 'Reference Range'.
Kwakhona, amanqanaba e-GGT kumadoda adla ngokuba phezulu kancinci kunawabasetyhini. La maxabiso anokutshintsha ngokuhamba kweminyaka.
Kuthetha ukuthini ukuba ne-GGT ephezulu? Ngaba kufuneka ndixhalabe?
Okokuqala, musa ukoyika xa ubona inqanaba eliphezulu le-GGT. Inqanaba eliphezulu le-GGT luphawu nje lokuba unokuba nesifo okanye imeko esonakalisa isibindi sakho. Oko akuthethi ukuba unesifo esithile.
Le theyibhile ingezantsi idwelisa izizathu ezininzi zokuba kutheni amanqanaba e-GGT enokunyuka.
| Izizathu ezinokwenzeka | Ingcaciso elula |
|---|---|
| Izizathu ezinxulumene nesibindi | |
| I-Hepatitis | Ukudumba kwesibindi ngenxa yosulelo lwentsholongwane okanye utywala. |
| Isifo sokuqina kwesibindi | Ukuvaleka kwesibindi ngenxa yomonakalo ohlala ixesha elide. |
| I-Cholestasis | Ukuvaleka kokuhamba kwenyongo esibindini. |
| Isifo sesibindi esibangelwa butywala | Ukonakala kwesibindi ngenxa yokusela utywala kakhulu. |
| Isifo sesibindi esinamafutha | Ukufakwa kwamafutha kwiiseli zesibindi. |
| Ukuncipha kokunikezelwa kwegazi esibindini (iLiver Ischemia) | Ukungabikho kwegazi eliya kwizicubu zesibindi. |
| Iithumba zesibindi okanye umhlaza | Ukukhula okungaqhelekanga kweeseli esibindini. |
| Ezinye izizathu | |
| Ukuxhomekeka kutywala | Ukusetyenziswa kotywala obuninzi ixesha elide. |
| I-Pancreatitis okanye umhlaza | Ukudumba okanye umhlaza wepancreas. |
| Isifo seswekile | Ukungakwazi ukulawula amanqanaba eswekile egazini. |
| Ukungaphumeleli kwentliziyo okubangelwa kukunganyamezelani | Intliziyo ayikwazi ukupompa igazi elaneleyo emzimbeni. |
| Amanye amayeza | Umzekelo: Iziyobisi ezifana ne-`Phenobarbital`, `Phenytoin`, `Warfarin`. |
| Ukutshaya | Ukutshaya kunokubangela amanqanaba aphezulu e-GGT. |
Kodwa khumbula kwakhona, ukuba nje i-GGT yakho iphezulu akuthethi ukuba unesi sifo. Ugqirha wakho uza kwenza isigqibo ngokusekelwe kule ngxelo, kunye novavanyo lwegazi, iimpawu zakho, kunye nembali yakho epheleleyo yempilo.
Ndifanele ndithethe nini nogqirha?
Ukuba unemibuzo malunga nokuba kutheni ucelwe ukuba wenze uvavanyo lwe-GGT okanye ukuba ingxelo yakho ithetha ukuthini, qiniseka ukuba ubuza ugqirha wakho.
Kuqhelekile ukukhangela kwi-intanethi xa ubona utshintsho kwingxelo. Kodwa ekubeni uvavanyo olufana ne-GGT lodwa lungenakukwazi ukufumanisa isifo esithile, ukukhangela ngolo hlobo kuya kubangela uloyiko olungeyomfuneko.
Ngugqirha wakho kuphela onokuchaza kakuhle intsingiselo yokwenyani yamaxabiso akwingxelo yakho kunye nendlela achaphazela ngayo impilo yakho. Uza kukucebisa ngokusekelwe kwimeko yakho epheleleyo.
Umyalezo Wokuya Ekhaya
- I-GGT yi-enzyme efumaneka kakhulu esibindini. Iyavavanywa ukuba kukho umonakalo wesibindi okanye ukuvaleka kwe-bile duct.
- Musa ukoyika ukuba ubona inqanaba eliphezulu le-GGT. Luphawu nje lokugula, hayi ukuxilongwa okuqinisekileyo.
- Oogqirha bahlala bethelekisa ingxelo yeGGT nezinye iimvavanyo zesibindi ezifana ne-ALT, AST, kunye ne-ALP.
- Ukusetyenziswa kotywala, ukutshaya, kunye namanye amayeza nako kunokunyusa amanqanaba e-GGT. Musa ukusela utywala ngaphambi kovavanyo.
- Ukuba unemibuzo okanye iinkxalabo malunga nengxelo yakho, thetha nogqirha wakho. Kulapho uza kufumana khona ulwazi oluchanekileyo kunye nesikhokelo.
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