Wena, okanye mhlawumbi umntwana wakho, usenokuba uxelelwe ngugqirha wakho ukuba uqalise ukuthatha iyeza elibizwa ngokuba yi-Alpelisib (igama lophawu: Vijoice). Xa usiva igama leyeza elikhethekileyo, kuyinto eqhelekileyo ukuba kuvele imibuzo emininzi engqondweni yakho, efana nokuthi "Le nto yenze ntoni?", "Ndingayithatha njani?", "Zithini izilumkiso?" Ngoko ke ungoyiki. Namhlanje, siza kuthetha ngale yeza elibizwa ngokuba yi-Alpelisib ngendlela ecacileyo nelula.
Luhlobo luni lonyango i-Alpelisib?
Ngamafutshane, i-Alpelisib liyeza elilawula ukukhula okungaqhelekanga nokungalawulekiyo kweeseli ezithile emzimbeni. Eli yeza lisetyenziselwa ngokukodwa ukunyanga imeko apho iindawo ezithile zomzimba (umzekelo, ingalo, umlenze, okanye ezinye izicwili) ziba nkulu kakhulu ngenxa yotshintsho kwijini ebizwa ngokuba yi-PIK3CA . Le meko siyibiza ngokuba yi -PIK3CA-related overgrowth spectrum (PROS) . Eli yeza lisebenza ngokuvala indlela yokubonisa ebangela ukukhula okungaqhelekanga kweeseli, ngaloo ndlela lilawula isifo.
Ugqirha wakho angakunika oku nakwezinye iimeko zonyango, ngoko ke ukuba unemibuzo, thetha nogqirha wakho ngayo.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ukuze ukhuseleke kwaye ufumane okuninzi kumayeza, kubalulekile ukuxelela ugqirha wakho olu lwazi ngaphambi kokuba uqale i-Alpelisib.
- Ukuba unesifo seswekile: Sixelele ukuba sele unesifo seswekile okanye amazinga aphezulu eswekile egazini.
- Izifo zemiphunga: Ukuba unesifo semiphunga, esifana ne-asthma okanye i-pneumonia.
- Ii-Allergies: Qiniseka ukuba uxelela ugqirha wakho ukuba une-allergies kwi-Alpelisib okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukukhulelwa: Ukuba ukhulelwe, uzama ukukhulelwa, okanye unesikrokro sokuba ukhulelwe.
- Ukuba ungumama oncancisayo: Ukuba uncancisa umntwana.
Xa ugqirha esazi ngezi zinto, kuya kuba lula kuye ukuba acebe unyango olukufaneleyo.
Ndingayisebenzisa njani kanye kanye le yeza?
Kubaluleke kakhulu ukulandela imiyalelo echanekileyo yokusebenzisa eli yeza.
- Sela amayeza kanye njengoko ugqirha ewayalele, ngexesha elifanayo yonke imihla .
- Musa ukuyisika okanye ukuyihlafuna le pilisi. Ginya yonke ngamanzi.
- Kungcono ukusela amayeza kunye nesidlo .
- Qhubeka usela amayeza de ugqirha wakho akuxelele ukuba uyeke. Musa ukuyeka ngequbuliso, nokuba uzive ungcono.
Yintoni omawuyenze ukuba ipilisi kunzima ukuyiginya?
Abanye abantu, ingakumbi abantwana, banengxaki yokuginya iipilisi. Kwimeko enjalo, nantsi indlela yokwenza oku:
1. Beka ithebhulethi kwiglasi ene-2-4 ounces (malunga ne-60-120 ml) yamanzi.
2. Emva kwemizuzu emi-5, tyumza ithebhulethi kakuhle ngecephe elicocekileyo uze uyixube kakuhle ide inyibilike emanzini.
3. Sela lo mxube ngoko nangoko.
4. Emva koko, yongeza ezinye iipunipoyi zamanzi ezi-2-3 kwiglasi enye, uhlambe naliphi na iyeza eliseleyo kwiglasi, uze ulisele. Yenza oku ngendlela yokuba kungabikho nethontsi elinye leyeza elichithwayo.
Kubalulekile: Eli yeza likwanikwa abantwana abaneminyaka engaphezu kwemi-2 ubudala kwiimeko ezithile ezikhethekileyo. Nangona kunjalo, ngugqirha wakho kuphela onokugqiba ngale nto. Ke ngoko, ukuba unika umntwana eli yeza, landela imiyalelo kagqirha ngononophelo.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu (ukugqithisa)?
Ukuba ucinga ukuba usele kakhulu eli yeza, ungalibazisi. Tsalela umnxeba iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-9 ngaphambi kokuba uthathe idosi elandelayo xa ukhumbula (oko kukuthi, emva kwexesha elingaphezulu kweeyure ezili-9), yitsibe idosi oyiphosileyo. Thatha nje idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye ukuze ubuyisele idosi oyiphosileyo.
Amanye amayeza anokusebenzisana nalo mayeza (Ukusebenzisana kwamayeza)
Amanye amayeza owasebenzisayo anokuchaphazela ukusebenza kwe-Alpelisib kwaye achaphazele ukusebenza kwayo okanye iziphumo ebezingalindelekanga. Ngoko ke, xelela ugqirha wakho ukuba usebenzisa naliphi na kula mayeza alandelayo okanye naziphi na ezinye izongezo, iivithamini, okanye amayeza emifuno.
- Amanye amayeza asetyenziselwa isifo sokuwa: Umzekelo, `(Carbamazepine)`, `(Phenobarbital)`, `(Phenytoin)`.
- `I-Cyclosporine`
- `Eltrombopag`
- `Enzalutamide`
- `IMitotane`
- `Rifampin` (iyeza lesifo sephepha)
- `I-St. John's Wort` (unyango lwezityalo lwempilo yengqondo)
- 'I-Sulfasalazine'
- `I-Warfarin` (iyeza elinikwa ukuthintela ukujiya kwegazi)
Olu luhlu aluphelelanga, ngoko ke kungcono ukwazisa ugqirha wakho malunga nawo onke amayeza owasebenzisayo.
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa iyeza
- Ukuhlolwa rhoqo ngugqirha: Buza ugqirha wakho rhoqo ukuze ubone ukuba iimpawu zakho ziyaphucuka okanye ziyanda. Musa ukulibazisa uvavanyo lwegazi oluyimfuneko (umsebenzi wegazi).
- Iimpendulo eziqatha zesikhumba: Abanye abantu banokuba neempendulo eziqatha zesikhumba nakwiiveki emva kokuba beqalise eli yeza.Xelela ugqirha wakho ngoko nangoko ukuba unesiqhushumbisi kunye neempawu ezifana nomkhuhlane okanye umkhuhlane. Ezi ziqhushumbisi zingajika zibe bomvu okanye zibe mfusa, emva koko zibe namaqhubu kwaye ziqhekeke. Okanye ukuba ubona isiqhushumbisi esibomvu ebusweni bakho, emilebeni, entanyeni, okanye emakhwapheni kunye ne-lymph nodes ezidumbileyo, tsalela ugqirha wakho ngoko nangoko.
- Urhudo olunzima kunye nokuphelelwa ngamanzi emzimbeni: Xelela ugqirha wakho ukuba unesifo sorhudo esinzima, ukuhlanza, okanye ukubila kakhulu . Ukulahlekelwa lulwelo oluninzi emzimbeni wakho (ukuphelelwa ngamanzi emzimbeni) kunokuba yingozi ngelixa usebenzisa eli yeza.
- Iswekile ephezulu egazini (iHyperglycemia): Eli yeza linokubangela iswekile ephezulu egazini. Le ngozi iphezulu kubantu abasele benesifo seswekile. Xelela ugqirha wakho ukuba uziva unxaniwe ngaphezu kwesiqhelo, uchama rhoqo, uzive udiniwe ngendlela engaqhelekanga, okanye ungaboni kakuhle .
- Umlomo owomileyo: Usenokuba nomlomo owomileyo. Oku kunokulawulwa zizinto ezifana nokuhlafuna itshungama engenaswekile kunye nokusela amanzi amaninzi. Nangona kunjalo, ukuba ingxaki iyaqhubeka okanye inzima, xelela ugqirha wakho.
Isilumkiso esibaluleke kakhulu sokukhulelwa: Kuphephe ukukhulelwa ngokupheleleyo ngelixa usela eli yeza kwaye iveki enye emva kokuyeka iyeza. Amadoda afanele akuphephe ukuba nguyise womntwana ngelixa esela eli yeza kwaye iveki enye emva kokuyeka iyeza. Eli yeza linokubangela ingozi enkulu kusana olungekazalwa. Buza ugqirha wakho ngolwazi oluthe kratya malunga noku. Kwakhona, kuphephe ukuncancisa ngelixa usela eli yeza kwaye iveki enye emva kokuyeka iyeza.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
| Imiphumela | Inkcazo kunye nento omawuyenze |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Urhudo oluqatha | Ukuqunjelwa okungenakunqandeka. |
| Iswekile ephezulu egazini (iHyperglycemia) | Unxano olugqithisileyo, ukuchama rhoqo, ukudinwa kakhulu, ukubona izinto ezingaqhelekanga. |
| Ukulimala kwemiphunga | Ubunzima bokuphefumla, ukukhohlela, i-phlegm enegazi, iintlungu zesifuba, umkhuhlane. |
| Izifo ezinzulu zesikhumba | Ubomvu, amadyungudyungu, ulusu oluxobukayo (nangaphakathi emlonyeni). |
| Izinto omele uzixelele ugqirha wakho ukuba ziyaqhubeka okanye ziyakukhathaza | |
| Ulusu olomileyo | Ulusu olomileyo |
| Intloko ebuhlungu | Intloko ebuhlungu |
| Ukulahleka kweenwele | Ukulahleka kweenwele |
| Izilonda zomlomo okanye zomqala | Intlungu, ubomvu, okanye ukudumba okubangelwa zizilonda emlonyeni okanye emqaleni |
Ugcina njani amayeza akho ekhuselekile?
- Gcina kude nabantwana kunye nezilwanyana zasekhaya.
- Gcina kubushushu obuphakathi kwama-20 nama-25 degrees Celsius (68-77 Fahrenheit), obububushushu obuqhelekileyo begumbi.
- Musa ukusebenzisa amayeza aphelelwe lixesha.
- Xa ulahla amayeza angasetyenziswanga okanye aphelelwe lixesha, jonga ileyibhile ukuze ubone ukuba akhuselekile na ukuwalahla. Ukuba unamathandabuzo, buza ugqirha wakho. Ukuba akhuselekile ukuwalahla, susa iipilisi ebhotileni uze uzixube nento efana nekofu esetyenzisiweyo, umhlaba, okanye inkunkuma yekati, uzifake kwibhegi okanye kwisikhongozeli esivalwe kakuhle, uze uzilahle kwinkunkuma.
Umyalezo Wokuya Ekhaya
- I-Alpelisib liyeza elikhethekileyo, ngoko ke soloko ulithatha kanye njengoko ugqirha wakho ekuxelele, nangexesha elifanelekileyo.
- Xelela ugqirha wakho malunga neminye imithi oyithathayo kunye nezinye iingxaki zempilo onazo ngaphambi kokuba uqalise amayeza.
- Soloko ulumkele iingxaki ezinkulu zesikhumba (umkhuhlane, ukurhawuzelela, amadyungudyungu) kunye neempawu zeswekile ephezulu yegazi (ukoma kakhulu, ukuchama rhoqo). Xelela ugqirha wakho ngoko nangoko ukuba kukho into oyiphawulayo.
- Kubaluleke kakhulu ukuphepha ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza kwaye emva kweveki enye uyekile.
- Eli yeza lelakho wedwa. Ungaze wabelane ngalo nabanye.
- Ukuba unemibuzo, iinkxalabo, okanye amathandabuzo malunga namayeza, ungaqikeleli, kodwa thetha nogqirha wakho ngqo.
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