Ngaba uyayazi iyeza lomhlaza iBrigatinib? Makhe sithethe ngalo!

Ngaba wena okanye umntu omaziyo ukhe wanikwa iyeza elibizwa ngokuba yiBrigatinib lokunyanga imeko efana nomhlaza wemiphunga? Makhe sithethe kancinci ngeli yeza, indlela yokulisebenzisa, kunye nezinto ekufuneka uzazi. Kuqhelekile ukuba nemibuzo emininzi engqondweni yakho ngexesha elinje. Ngoko ke, ndiyathemba ukuba olu lwazi luza kukunceda.

Luhlobo luni lweyeza iBrigatinib?

Ngamafutshane, iBrigatinib liyeza elikhethekileyo elinceda ekumiseni ukukhula kweeseli zomhlaza . Lisebenza ngokujolisa kwiiproteni ezithile ngaphakathi kweeseli zomhlaza kwaye lizithintele ekusebenzeni kwazo. Lisetyenziswa ngokukodwa ukunyanga uhlobo lomhlaza olubizwa ngokuba yi -non-small cell lung cancer .

Eli yeza lingasetyenziswa noogqirha kwezinye iimeko, ngoko ke ukuba unemibuzo engaphezulu malunga noku, kungcono ubuze ugqirha wakho okanye ingcali yezonyango.

Ndimele ndimxelele ntoni ugqirha ngaphambi kokuba ndiqalise eli yeza?

Ngaphambi kokuba uqale ukusebenzisa i-brigatinib, kubaluleke kakhulu ukuxelela ugqirha wakho ngazo zonke iimeko zakho zempilo. Kubaluleke kakhulu ukuxelela ugqirha wakho ukuba unenye okanye ngaphezulu kwezi meko zilandelayo:

• Ukuba unesifo seswekile (iDiabetes Mellitus) .
• Ukuba unesifo samehlo.
• Ukuba une- high blood pressure .
• Ukuba ukhe waba nesifo esifana ne -pancreatitis ngaphambili.
• Ukuba unesifo sezintso.
• Ukuba unesifo sesibindi.
• Ukuba unesinye isifo semiphunga.
• Ukuba unesifo esibizwa ngokuba yi-'slow heartbeat'.
• Ukuba unengxaki yokubona.
• Ukuba une-allergy kwi-brigatinib, amanye amayeza, ukutya, imibala yokwenziwa, okanye izithinteli.
• Ukuba uzama ukukhulelwa okanye ukhulelwe okwangoku .
• Ukuba ungumama oncancisayo .

Ngokuxelela ezi zinto kwangaphambili, ugqirha unokucwangcisa unyango olukufaneleyo.

Ndingayisebenzisa njani le yeza?

Eli yeza liza likwimo yeepilisi kwaye kufuneka lithathwe ngomlomo. Kubalulekile ukulithatha eli yeza ngexesha elifanayo yonke imihla , kanye njengoko ugqirha wakho ekuyalele.

Kubalulekile: Musa ukuphula, ukutyumza, okanye ukuhlafuna ithebhulethi. Ginya ithebhulethi yonke ngamanzi.

Eli yeza lingasetyenziswa ngaphambi okanye emva kokutya. Nangona kunjalo, ukuba uziva ungakhululekanga esiswini, kungcono ukulisebenzisa kunye nokutya. Kufuneka uqhubeke nokusebenzisa eli yeza de ugqirha wakho akuxelele ukuba uyeke.

Enye into ebalulekileyo:Musa ukusela ijusi yegrapefruit ngelixa usela eli yeza. Oku kusenokuchaphazela ukusebenza kakuhle kweli yeza.

Kufuneka kuqatshelwe ngokukodwa xa kunikwa abantwana eli yeza, ngoko ke thetha nogqirha wakho ngalo.

Ukugqithisa amayeza: Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, fowunela iziko lolawulo lwetyhefu elikufutshane okanye igumbi likaxakeka ngokukhawuleza.

Nceda uqaphele: Eli yeza limiselwe wena kuphela. Musa ukwabelana ngalo nabanye abantu nangasiphi na isizathu.

Wenza ntoni ukuba uphoswe yintlanganiso yamayeza?

Ukuba uphoswe yidosi, yiyeke. Thatha idosi elandelayo ngexesha eliqhelekileyo. Musa ukuthatha iidosi ezimbini ngaxeshanye ukuze ubuyisele idosi ephoswe yidosi.

Ziziphi ezinye izinto ezinokusebenzisana nale mithi?

Eli yeza libizwa ngokuba yiBrigatinib lisenokusebenzisana namanye amayeza owasebenzisayo. Ukuba oku kuyenzeka, isiphumo salo yeza sinokuncitshiswa okanye sinyuke, okanye iziphumo ebezingalindelekanga zinyuke. Ngoko ke, kufuneka uxelele ugqirha wakho ngezinto ezilandelayo ozisebenzisayo:

• Amanye amayeza okubulala iintsholongwane ( umz. i-erythromycin, i-clarithromycin)
• Amanye amayeza okulwa neentsholongwane asetyenziselwa i-HIV okanye i-AIDS
• Amanye amayeza osulelo lwefungus (umz., i-ketoconazole, i-itraconazole, i-posaconazole)
• Amanye amayeza anikwayo kwiimeko ezifana nokuxhuzula (umz. i-carbamazepine, i-phenobarbital, i-phenytoin)
• Ijusi yeGrapefruit
• I-Rifampin

Olu luhlu aluphelelanga. Ngoko ke xelela ugqirha wakho ngawo onke amayeza owasebenzisayo (amayeza amiselweyo, athengiswa ngaphandle kwemvume kagqirha, iimveliso zemifuno, iivithamini, kunye nezongezo zesondlo). Kwakhona, xelela ugqirha wakho ukuba uyatshaya, usela utywala, okanye usebenzisa iziyobisi ezingekho mthethweni. Ezinye zezi zinto zinokudibana nalo mayeza.

Zeziphi izinto ekufuneka uzilumkele xa usebenzisa eli yeza?

Ungaziva ungaphilanga okanye ugula ngelixa usebenzisa eli yeza. Oku kuqhelekile, njengoko i-chemotherapy ikwachaphazela iiseli eziphilileyo. Xelela ugqirha wakho ngazo naziphi na iziphumo ebezingalindelekanga ozifumanayo. Qhubeka uthatha iyeza nokuba likwenza uzive ungonwabanga, de ugqirha wakho akuxelele ukuba uyeke.

Ukukhulelwa, ukuncancisa kunye nokuzala

• Kuphephe ukukhulelwa: Kufuneka ukuphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye emva kweenyanga ezi-4 emva kokuyeka iyeza. Abafazi kufuneka baxelele ugqirha wabo ngoko nangoko ukuba baceba ukukhulelwa okanye bacinga ukuba banokuba bakhulelwe.
• Kwicala lamadoda:Amadoda afanele akuphephe ukuba nguyise womntwana ngelixa esela eli yeza kwaye kangangeenyanga ezi-3 emva kokuyeka ukusebenzisa eli yeza, kuba linokubangela ingozi enkulu kumntwana ongekazalwa. Buza ugqirha wakho ukuba akunike ulwazi oluthe kratya ngalo mba.
• Ukuncancisa: Kuphephe ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye iveki enye emva kokuba uyekile iyeza.
• Iziphumo ekuzaleni: Eli yeza lisenokuchaphazela amandla akho okukhulelwa. Ukuba uneengxaki malunga nokuzala kwakho, thetha nogqirha wakho.

Amanye amanqaku abalulekileyo

• Umngcipheko wokosuleleka: Eli yeza lisenokunciphisa amandla omzimba wakho okulwa nosulelo. Ngoko ke, ukuba ubonakalisa iimpawu ezifana nomkhuhlane, ukubanda, umphimbo obuhlungu, okanye impumlo egobhozayo, tsalela umnxeba ugqirha wakho ngoko nangoko ukuze akunike ingcebiso. Musa ukuzinyanga. Zama ukuhlala kude nabantu abagulayo.
• Lumka ngeepilisi zokuthomalalisa iintlungu: Ngaphandle kokuba ugqirha wakho ekucebisile ukuba wenze njalo, musa ukusebenzisa iipilisi zokuthomalalisa iintlungu kunye nezokuthomalalisa umkhuhlane ezifana ne-aspirin, i-acetaminophen, i-ibuprofen, i-naproxen, kunye ne-ketoprofen. Ezi zinokuwuthomalalisa umkhuhlane.
• Utshintsho embonweni: Ukuba ufumana naluphi na utshintsho embonweni wakho (umz., umbono ofipheleyo, umbono ophindwe kabini), xelela ugqirha wakho ngoko nangoko.
• Uvakalelo elangeni: Eli yeza lingenza ulusu lwakho lube buthathaka ngakumbi elangeni. Ngoko ke kuphephe ukuchatshazelwa lilanga kangangoko unako. Ukuba uyaphuma phandle, nxiba impahla egquma ulusu lwakho kwaye usebenzise i-sunscreen. Musa ukusebenzisa izibane zelanga okanye iibhedi/ii-booths zelanga.
• Iingxaki zemisipha: Ukuba ufumana iintlungu zemisipha okanye ubuthathaka, ugqirha wakho angakuxelela ukuba uyeke ukusebenzisa eli yeza. Ukuba ezi ngxaki zemisipha ziyaqhubeka emva kokuyeka ukusebenzisa iyeza, xelela ugqirha wakho.
• Iswekile ephezulu egazini: Eli yeza linokubangela iswekile ephezulu egazini. Ukuba unesifo seswekile, buza ugqirha wakho ukuba ufuna ukwenza naluphi na utshintsho kwindlela otya ngayo okanye amayeza akho.
• I-Acidosis: Eli yeza ngamanye amaxesha linokubangela inqanaba eliphezulu le-asidi egazini . Ukuba ufumana iimpawu ezifana nokucaphuka, ukuhlanza, iintlungu zesisu, ukudinwa okungaqhelekanga, okanye ubunzima bokuphefumla, yeka ukuthatha eli yeza ngoko nangoko uze ufowunele ugqirha wakho. Ukuba kunokwenzeka, jonga umchamo wakho ukuba awunazo na ii-ketones usebenzisa i-ketone dipstick.

Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?

Njengazo zonke iziyobisi, i-brigatinib inokubangela ezinye iziphumo ebezingalindelekanga. Ezinye zinzima kwaye kufuneka zixelwe kugqirha wakho ngoko nangoko. Ezinye azinzima kangako, kodwa ukuba ziyaqhubeka okanye ziyakhathaza, kufuneka uxelele ugqirha wakho.

Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ngoko nangoko:

• Iimpendulo ze-allergy: ukurhawuzelela kwesikhumba, ukurhawuzelela, okanye ukudumba kobuso, imilebe, okanye ulwimi.
• Utshintsho kumbono
• Ukukhwehlela
• Ukuphefumla okuneziqhamo (oku kungaba luphawu lokuba nezinga eliphezulu leswekile egazini)
• Iswekile ephezulu egazini: Ukwanda kwendlala, ukoma, okanye ukuchama; ubuthathaka okanye ukudinwa okungaqhelekanga; ukubona okufipheleyo.
• Ukunyuka koxinzelelo lwegazi
• Usulelo: Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, iintlungu okanye ubunzima bokuchama.
• Ukulimala kwesibindi: Umchamo otyheli okanye omdaka omnyama; iimpawu ezifana nomkhuhlane oqhelekileyo wentsholongwane; ukuphelelwa ngumdla wokutya; iintlungu esiswini esingaphezulu ngasekunene; ubuthathaka okanye ukudinwa okungaqhelekanga; ukutyheli kwamehlo nolusu (njenge-jaundice).
• Ukulimala kwemisipha: Umchamo omnyama; ubunzima bokuchama okanye utshintsho kubungakanani bomchamo; ubuthathaka okanye ukudinwa okungaqhelekanga; iintlungu zemisipha; iintlungu zomqolo.
• I-Pancreatitis: Intlungu yesisu (oku kunokuphuma emqolo, kwaye kunokuba mandundu emva kokutya okanye xa kuchukunyiswa), umkhuhlane, isicaphucaphu, ukuhlanza, kunye nokubetha kwentliziyo ngokukhawuleza.
• Ukubetha kwentliziyo okucothayo: Ukuphelelwa ngumphefumlo; iintlungu zesifuba; isiyezi; ukuquleka, isiyezi; ukuziva ubuthathaka okanye udiniwe ngendlela engaqhelekanga.
• Ubunzima bokuphefumla

Iziphumo ebezingalindelekanga ezihlala zingadingi ngcebiso kagqirha (kodwa kufuneka zixelwe ukuba ziyaqhubeka okanye ziyakhathaza):

• Urhudo
• Intloko ebuhlungu
• Isicaphucaphu
• Ukuhlanza

Olu luhlu aluzizo zonke iziphumo ebezingalindelekanga. Ukuba ubona into engaqhelekanga, xelela ugqirha wakho.

Ndingaligcina njani iyeza? Ndenza ntoni ukuba kukho eliseleyo?

Ezi pilisi mazigcinwe kude nabantwana nezilwanyana zasekhaya .

Gcina kubushushu begumbi (phakathi kwama-20 nama-25 degrees Celsius, phakathi kwama-68 nama-77 degrees Fahrenheit). Musa ukusebenzisa amayeza aphelelwe lixesha, walahle.

Indlela yokulahla amayeza angasetyenziswanga okanye aphelelwe lixesha:

Eyona ndlela ilungileyo yokuphelisa ezi zinto kukuzithatha uziyise kwindawo enenkqubo yokubuyisela amayeza. Ungabuza ikhemesti yakho okanye amapolisa ngeendawo ezinjalo.

Ukuba akukho ndlela yokuyibuyisela, jonga ipakethi yamayeza okanye ilebheli ukuze ubone ukuba afanele alahlwe kwinkunkuma okanye ahlanjwe kwindlu yangasese. Ukuba awuqinisekanga, buza ugqirha wakho okanye ikhemisti. Ukuba kukhuselekile ukuwalahla kwinkunkuma, yenza oku kulandelayo:

1. Khupha iyeza kwisikhongozeli.

2. Zixube nezinto ezifana nenkunkuma yekati, umhlaba, kunye nekofu.

3. Beka lo mxube ebhegini okanye kwisikhongozeli uze uwuvale kakuhle.

4. Emva koko yifake kwisitya senkunkuma.

Okokugqibela, umyalezo obalulekileyo

Kweli nqaku, sixoxe ngezinto ezithile ngokubanzi malunga neyeza iBrigatinib. Aligubungeli zonke iinkcukacha. Ukuba unemibuzo malunga neli yeza, qiniseka ukuba uthetha nogqirha wakho, usokhemesti, okanye umboneleli wezempilo. Banokukunika icebiso elifanelekileyo kwimeko yakho. Khumbula, ugqirha wakho ngumcebisi wakho ongcono.

` I-Brigatinib, amayeza omhlaza, umhlaza wemiphunga, Umhlaza wemiphunga ongengoweeseli ezincinci, iziphumo ebezingalindelekanga, amayeza, unyango lomhlaza