Usenokuba ukhe weva igama elithi Hydroxychloroquine kwiindaba ngexesha lobhubhane we-COVID. Kodwa eneneni liyeza elidala kakhulu eliye lasetyenziswa ukusukela ngeminyaka yoo-1940. Kwimihla yokuqala, oogqirha babelisebenzisa ukunyanga i-malaria. Namhlanje, lisetyenziswa kakhulu kwezinye iimeko zonyango. Namhlanje, siza kuthetha ngento eli yeza elisetyenziselwa yona, zeziphi iziphumo ebezingalindelekanga elinokubangelwa zizo, kunye nento ekufuneka uyilumkele xa ulisebenzisa.
Ingaba eli yeza lifanelekile ngokwenene kwi-Covid-19?
Lo ngumbuzo abantu abaninzi abanawo. Ngamafutshane, hayi . I-World Health Organisation (WHO) ayicebisi i-hydroxychloroquine ekuthinteleni okanye kunyango lwe-COVID-19. Bafikelele kwesi sigqibo emva kophando olunzulu.
Khawucinge nje, izifundo ezi-6 zabantu abangamawaka abangenayo i-COVID-19 zifumanise ukuba eli yeza alinampembelelo ekubathinteleni ekubeni bafumane i-COVID, bangene esibhedlele, okanye bafe. Kwaye izifundo ezingama-30 zabaguli abangaphezu kwe-10,000 be-COVID-19 zifumanise ukuba eli yeza alizange linciphise imfuneko yee-ventilators okanye umngcipheko wokufa. Yiyo loo nto lingacetyiswa okwangoku kwi-COVID-19.
Ngoko ke zeziphi izifo ezisetyenziselwa eli yeza?
IHydroxychloroquine isetyenziswa kakhulu namhlanje kwizifo ezichaphazela amasosha omzimba. Ngoku mhlawumbi uyazibuza ukuba yintoni leyo.
Ngamafutshane, oku kwenzeka xa inkqubo yokuzikhusela yomzimba wethu, inkqubo yokuzikhusela, ihlasela ngempazamo iiseli zethu ezisempilweni kunye nezicubu. Oku kubangela ukudumba kunye nomonakalo kumalungu, izihlunu, kwaye ngamanye amaxesha amalungu angaphakathi.
Ugqirha wakho angakunika eli yeza ukuba unenye yezi meko zilandelayo:
- Irheumatoid arthritis
- I-systemic lupus erythematosus (SLE)
- Isifo samathambo esibangelwa yi-Juvenile idiopathic
- Isifo se-Antiphospholipid
- Isifo sikaSjogren esiPhambili
Iingcali azikaqiniseki kakuhle ukuba eli yeza lisebenza njani, kodwa zicinga ukuba litshintsha indlela iiseli zomzimba ezisabelana ngayo. Lisenokucima nezinye zeenkqubo ezibangela ukudumba.
Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?
Njengalo naliphi na iyeza, i-hydroxychloroquine inokubangela iziphumo ebezingalindelekanga. Nangona ingenguye wonke umntu ozifumanayo, ezinye iziphumo ebezingalindelekanga azibi kakhulu kwaye ziyaphela ngokuhamba kwexesha.
| Iziphumo ebezingalindelekanga eziqhelekileyo | |
|---|---|
| Isicaphucaphu | Ukuhlanza |
| Urhudo | Intlungu yesisu |
| Icebiso: Ukuze unciphise ezi ziphumo bezingalindelekanga, kunokuba luncedo ukuthatha eli yeza kunye nokutya . | |
Ukongeza, ezinye iimpawu ezilandelayo zinokwenzeka:
- Ukurhawuzelela okanye ukurhawuzelela eluswini
- Ukuba mnyama okanye ukufiphala kwesikhumba
- Utshintsho lweenwele (umz., utshintsho lombala)
- Ubuthathaka bemisipha
- Utshintsho lweemvakalelo
- Ukukhala ezindlebeni
Iziphumo ebezingalindelekanga ezinzulu ekufuneka uzazi
Ezi zizinto ezinzulu kancinci, ngoko ke kubaluleke kakhulu ukuzazi ezi zinto.
Iziphumo entliziyweni
I-Hydroxychloroquine inokubangela utshintsho oluyingozi kwisingqisho sentliziyo. Oku kuyinyani ngakumbi ukuba uyithatha kunye namanye amayeza athile, njenge- azithromycin . Oku kunokubangela utshintsho kumsebenzi wombane wentliziyo. Ngokukodwa, inokubangela isantya sentliziyo esingaqhelekanga (i-ventricular tachycardia) okanye utshintsho oluyingozi kwisingqisho sentliziyo (ixesha le-QT elide).
Umonakalo wamehlo
Eli linqaku elibaluleke kakhulu. Nangona lingaqhelekanga, i-hydroxychloroquine inokubangela umonakalo kwi-retina yeliso.
Ungalibali ukuba eli yeza lingonakalisa amehlo akho. Kwezinye iimeko, usenokulahlekelwa nangumbono wakho ngonaphakade.
Le ngozi iyanda kubantu abafana nalaba:
- Kwabo baneminyaka engaphezu kwama-60 ubudala
- Kwabo bathatha iidosi eziphezulu zale chiza iminyaka engaphezu kwemi-5
- Kwabo banesifo esibi sezintso okanye sesibindi
- Kwabo sele benesifo samehlo okanye i-retina
Ngoko ke, ukuba usebenzisa eli yeza ixesha elide, kubalulekile ukuba amehlo akho ahlolwe rhoqo ngugqirha wamehlo.Ugqirha wakho uza kukuxelela ukuba uhlolwe amehlo akho kube kanye ngonyaka okanye ubuncinane kube kanye kwiminyaka emihlanu.
Ezinye iziphumo ezibi kakhulu
- Iingxaki zenkqubo yegazi: I-anemia inokwenzeka rhoqo, ingakumbi kubantu abaneengxaki zegazi ezifana nokungabikho kwe-G6PD okanye i-porphyria.
- Iingxaki zezintso
- Ukonakala kwesibindi okanye ukungasebenzi kakuhle kwaso
Ukusebenzisana neziyobisi
I-Hydroxychloroquine inokusebenzisana namanye amayeza. Ingatshintsha indlela esebenza ngayo okanye yonyuse umngcipheko weziphumo ebezingalindelekanga. Ngoko ke kubalulekile ukuxelela ugqirha wakho malunga namayeza, iivithamini, okanye izongezo ozisebenzisayo.
| Uhlobo lweyeza | Izinto ekufuneka ziqwalaselwe |
|---|---|
| Amayeza angafanele asetyenziswe kunye | ICisapride, iDronedarone, iPimozide, iThioridazine |
| Amayeza anokubangela iziphumo ebezingalindelekanga | I-Digoxin, i-insulin okanye amanye amayeza esifo seswekile, iMefloquine, amayeza esifo sokuwa, iMethotrexate, iCyclosporine |
| Amayeza anokubangela ezinye iziphumo ebezingalindelekanga | I-Praziquantel, ii-Antacids, i-Kaolin, i-Cimetidine, i-Ampicillin |
Ukuba usela i-tamoxifen yomhlaza webele, thetha nogqirha wakho ngayo loo nto. Kusenokungafaneleki ukuthatha la mayeza mabini kunye ixesha elingaphezu kweenyanga ezi-6.
Ngubani onokusela eli yeza? Ngubani ongenakulisela?
I-Hydroxychloroquine ikhuselekile kubantu abadala abaninzi nabantwana. Ugqirha wakho uya kumisela idosi efanelekileyo ngokusekwe kubunzima bomzimba wakho.
Nangona uphando lubonise ukuba eli yeza likhuselekile ukulisebenzisa ngexesha lokukhulelwa okanye lokuncancisa,Qiniseka ukuba uthetha nogqirha wakho malunga namayeza owasebenzisayo.
Ukuba une -psoriasis , isifo solusu, lumka ngaloo nto kuba eli yeza linokwenza iimpawu zakho zibe zimbi ngakumbi.
Ngubani ongafanele athathe eli yeza?
Ukuba une-aleji kwamanye amayeza aqulethe iikhompawundi ze-4-aminoquinoline, ezifana ne-chloroquine, akufanele uthathe i-hydroxychloroquine.
Ukuba ufumana iimpawu ze-allergy, yiya kwi-emergency department (ETU) ekufutshane nawe ngoko nangoko. Ezi mpawu ziquka:
- Ukudumba komqala, umlomo, okanye ubuso
- Ukuqhambuka kwesikhumba okanye amadyungudyungu
- Ukurhawuzelela okukhulu
Umyalezo Wokuya Ekhaya
- I-Hydroxychloroquine liyeza elisetyenziswa kakhulu ukunyanga izifo ezihlasela amajoni omzimba ezifana ne-rheumatoid arthritis kunye ne-lupus. Alikhuthazwa kwi-COVID-19.
- Eli yeza linokubangela iziphumo ebezingalindelekanga ezinzulu entliziyweni ingakumbi emehlweni.
- Ukuba uthatha eli yeza ixesha elide, kubalulekile ukuba uhlolwe amehlo rhoqo njengoko ugqirha wakho ekucebisile.
- Yazisa ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo.
- Ungaze uqale okanye uyeke ukusebenzisa eli yeza ngaphandle kwengcebiso kagqirha.
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