Kumntu olwa nomhlaza okanye umntu okwintsapho yakhe, kuyinto eqhelekileyo ukuba nemibuzo emininzi kunye noloyiko xa ugqirha wakho ekunika iyeza elitsha. "Lithini eli yeza?", "Ngaba liza kunceda ngokwenene?", "Ngaba kukho iziphumo ebezingalindelekanga?" Usenokuba uzibuza. Ngaba wakha wazibuza ngesitofu seCemiplimab? Ngoko masithethe ngaso ngendlela enobuhlobo nelula.
Luhlobo luni lweyeza iCemiplimab?
Ngamafutshane, iCemiplimab sisitofu esikhethekileyo esisetyenziselwa ukunyanga iintlobo ezithile zomhlaza, njengomhlaza wolusu kunye nomhlaza wemiphunga. Ikwiqela lamayeza abizwa ngokuba yi-"monoclonal antibody".
Cinga ngako, imizimba yethu inenkqubo yokuzikhusela yangaphakathi esikhusela kwizifo, ebizwa ngokuba yinkqubo yokuzikhusela, akunjalo? Iiseli zomhlaza luhlobo lweseli olunobuqili kakhulu. Ngamanye amaxesha ziyazimela kwinkqubo yethu yokuzikhusela, ziyiqhathe, kwaye zikhule.
Isitofu sokugonya seCemiplimab senza into ekrelekrele kakhulu. Sithintela iproteni ethile enceda iiseli zomhlaza zikhule. Eli yeza ke liyayithintela. Oku kuthetha ukuba iiseli zomhlaza azikwazi ukuzimela kwinkqubo yethu yokuzikhusela. Iiseli zethu zokuzikhusela zinokuzibona iiseli zomhlaza, zizihlasele, kwaye zizitshabalalise. Oku kuthetha ukuba eli yeza lisebenzisa ukhuselo lomzimba wakho ukunceda ukulwa nomhlaza.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ngaphambi kokuba uqalise olu nyango, kubaluleke kakhulu ukwazisa ugqirha wakho ngembali yakho epheleleyo yempilo. Ngenxa yokuba eli yeza lisebenza kunye nenkqubo yethu yokuzikhusela komzimba, kufuneka uqwalaselwe ngokukodwa ukuba uneengxaki ezithile zempilo.
Ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelela ugqirha wakho:
- Ukuba ukhe wafakelwa i-allogeneic stem cell: Olu lulwazi olubaluleke kakhulu.
- Izifo ezizikhusela ngokwazo: Ukuba unesifo apho amajoni omzimba ahlasela iiseli zawo eziphilileyo, ezifana nesifo sikaCrohn, i-ulcerative colitis, okanye i-lupus.
- Isifo seswekile: Ukuba sele unesifo seswekile okanye ukuba kukho umntu kusapho lwakho onaso.
- Izifo zenkqubo yemithambo-luvo: Ukuba unezifo ezinxulumene nemithambo-luvo ezifana ne-'Myasthenia gravis' okanye i-'Guillain-Barre syndrome'.
- Ukuba ukhe wafakelwa amalungu omzimba (`ukufakelwa amalungu omzimba`): Ukuba ukhe wafakelwa amalungu omzimba afana nezintso okanye isibindi.
- Ukuba ufumana okanye usandula ukufumana unyango lwe-radiation.
- Isifo se-thyroid: Ukuba unemeko apho i-thyroid gland isebenza kakhulu okanye ingasebenzi ngokwaneleyo.
- Ukuba uzama ukukhulelwa okanye ukhulelwe okwangoku:Oku kubaluleke kakhulu. Eli yeza linokubangela ingozi enkulu kumntwana ngexesha lokukhulelwa.
- Ukuba ungumama oncancisayo.
- Ukuba ukhe waba ne-allergy kwi-Cemiplimab okanye naliphi na elinye iyeza, ukutya, okanye idayi.
Khumbula, kubaluleke kakhulu kukhuseleko lwakho ukuxelela ugqirha wakho ngengxaki yempilo encinci onayo.
Indlela yokusebenzisa amayeza nezinto ekufuneka uzazi
Eli yeza aliyonto onokuyisebenzisa ekhaya. Liyeza elinikwa ngesisombululo setyuwa (esifakwe emthanjeni) esibhedlele okanye ekliniki liqela lezonyango eliqeqeshiweyo.
- Okufanele ukwenze ukuba uphoswe yidosi: Kubaluleke kakhulu ukuya kugqirha wakho kwaye ufumane unyango lwakho kanye ngemihla emiselweyo. Ukuba ngesizathu esithile awukwazi ukuya ngomhla omiselweyo, fowunela iqela lakho lezonyango ngokukhawuleza uze ubazise.
- Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?: Oku kunikwa esibhedlele ngoko ke amathuba okuba oku kwenzeke mancinci kakhulu. Nangona kunjalo, ukuba ucinga ukuba ukhe wakwenza oko, fowunela iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
- Ukukhulelwa nokuncancisa: Eli yeza alicetyiswa ukuba uzama ukukhulelwa. Uza kuvavanywa ukuqinisekisa ukuba awukhulelwanga ngaphambi kokuba uqale unyango. Kufuneka usebenzise uhlobo lokuthintela ukukhulelwa oluthembekileyo ngexesha lonyango kunye neenyanga ezi-4 emva kokuyeka unyango . Kwakhona, musa ukuncancisa umntwana wakho ngexesha lonyango kunye neenyanga ezi-4 emva kokuyeka unyango.
Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?
Njengalo naliphi na iyeza elinamandla, iCemiplimab inokubangela ezinye iziphumo ebezingalindelekanga. Oku kungenxa yokuba eli yeza lisebenza kwiiseli zomhlaza nakwiiseli eziphilileyo ukuya kwinqanaba elithile. Eyona nto ibalulekileyo kukwazi oku kwaye wazise ugqirha wakho ngoko nangoko ukuba ufumana naziphi na iimpawu ezingaqhelekanga.
Masiqonde oku ngokucacileyo kwitheyibhile engezantsi.
| Uhlobo lwesiphumo esibi | Iimpawu onokuzifumana |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy / Iimpendulo ze-infusion | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi, ubunzima bokuphefumla, iintlungu zesifuba, ukuquleka. |
| Iimpendulo ezinzulu zesikhumba | Iimpawu zomkhuhlane okanye umkhuhlane ziquka amadyungudyungu abomvu okanye amfusa eluswini, ulusu oluxobukayo, izilonda emlonyeni, kunye nee-lymph nodes ezivuvukileyo entanyeni okanye emakhwapheni. |
| Iingxaki ezinxulumene nemiphunga | Ukukhohlela okomileyo okungachazekiyo, ubunzima bokuphefumla, ukuphefumla okuncinci. |
| Ukulimala kwesibindi | Intlungu kwicala eliphezulu lasekunene lesisu, ukuphelelwa ngumdla wokutya, isicaphucaphu, ukutyheli kolusu okanye amehlo, umchamo otyheli/omdaka omnyama, ukudinwa okungaqhelekanga. |
| Ukulimala kwezintso | Ukuphuma komchamo okunciphileyo, umchamo obomvu okanye omdaka, umchamo onamagwebu, ukudumba kwamaqatha, izandla, okanye iinyawo. |
| Iingxaki ngee-hormone glands (i-thyroid, ii-adrenals) | Ukubetha kwentliziyo ngokukhawuleza, ukwehla kobunzima, ukubila kakhulu, ukungcangcazela, ukuziva ubanda kakhulu, ukuqhina, ukunyuka kobunzima, ukudakumba, ukudinwa okungaqhelekanga, isiyezi. |
| Amanqanaba aphezulu eswekile egazini (i-Hyperglycemia) | Ukuziva unxaniwe kakhulu, ufuna ukuchama rhoqo, ukudinwa okungaqhelekanga, ukubona izinto ezingaqhelekanga. |
| Ezinye iimpawu ezinzulu | Utshintsho kwindlela yokubona, iintlungu zamehlo, intloko ebuhlungu kakhulu, iintlungu zentamo, ukuhlanza, urhudo olunegazi, iintlungu zesisu eziqatha, ukungaziva kakuhle kwamalungu omzimba, ubunzima bokuhamba. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga (kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka) | |
| Iziphumo ebezingalindelekanga eziqhelekileyo | Intlungu yamathambo, iintlungu zemisipha, urhudo. |
Ngaba kukho iingxaki ngamanye amayeza?
Akukafundwa ngokupheleleyo indlela eli yeza elisebenzisana ngayo namanye amayeza, iivithamini, okanye amayeza esintu. Ngoko ke, ukuze ukhuseleke, kubaluleke kakhulu ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka neevithamini.
Umyalezo Wokuya Ekhaya
- I-Cemiplimab liyeza elinamandla elivuselela amajoni omzimba wakho ukuba alwe neeseli zomhlaza.
- Ngaphambi kokuba uqale unyango, qiniseka ukuba uxelela ugqirha wakho ngazo zonke iimeko zakho zempilo (ingakumbi izifo zokuzikhusela komzimba, ukufakelwa amalungu omzimba).
- Ngelixa usela iyeza, lumka kakhulu malunga notshintsho lolusu, ubunzima bokuphefumla, utshintsho lombono, okanye ezinye iimpawu ezingaqhelekanga. Ukuba ubona nantoni na, yazisa ugqirha wakho ngoko nangoko.
- Ungaphoswa ziintlanganiso ezinikwe ngugqirha. Ukuba ufumana nayiphi na ingxaki, nceda usazise kwangethuba.
- Landela ngokungqongqo iingcebiso zonyango malunga nokukhulelwa nokuncancisa.
- Unyango lomhlaza luhambo olunzima. Kuqhelekile ukuba uzive ungakhululekanga kwaye usoyika ngeli xesha lohambo. Iqela lakho lezonyango likho ukuze likuxhase. Ngoko ke ungoyiki ukubuza nayiphi na imibuzo onayo.
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