Enye yezona ngxaki zinkulu kumntu ofumana unyango lomhlaza, nokuba yi-chemotherapy okanye unyango lwe-radiation, sisicaphucaphu nokuhlanza. Le meko yokungakwazi ukutya okanye ukusela nokuziva ubuthathaka inokuba yingxaki enkulu, akunjalo? I-Granisetron liyeza elisebenzayo kakhulu elicetyiswa ngoogqirha ukulawula oku kungakhululeki. Namhlanje, siza kuthetha ngeli yeza ngendlela elula kakhulu, kuquka indlela yokulisebenzisa kunye noko kufuneka ukuqaphele.
Yintoni iGranisetron?
Ngamafutshane, iGranisetron liyeza elinikwa ukuthintela isicaphucaphu nokuhlanza okubangelwa lunyango lwakho lomhlaza, oluyi- chemotherapy okanye unyango lwe-radiation . Lisebenza ngokuthintela imiqondiso ethunyelwa yingqondo namathumbu akho ukuze uzive ugula. Ngoko ke eli yeza linokukunceda uzive ungcono kancinci ngexesha lonyango lwakho.
Eli yeza lisenokuba phantsi kwamagama eempawu ezifana ne-'Granisol' okanye 'Kytril'. Nangona kunjalo, ugqirha wakho unokulinika phantsi kwegama eliqhelekileyo elithi 'Granisetron'. Ngamanye amaxesha eli yeza linikwa nakwisicaphucaphu esibangelwa zezinye izizathu, kwaye ugqirha wakho uya kukuchazela oku.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ngaphambi kokuba uqale iGranisetron, kubaluleke kakhulu ukunika ugqirha wakho ingxelo epheleleyo ngempilo yakho, ingakumbi ezi zinto zilandelayo:
- Ukuba unesifo sesibindi.
- Ukuba ukhe waba ne-allergy kwi-Granisetron, i-Ondansetron (elinye iyeza lokunyanga isicaphucaphu), okanye naliphi na elinye iyeza, ukutya, iidayi, okanye izithinteli .
- Ukuba ukhulelwe okanye uzama ukukhulelwa .
- Ukuba ungumama oncancisayo .
- Ukuba une - heart rhythm engaqhelekanga okanye ukuba kukho umntu kusapho lwakho onesifo esinjalo.
Ngokusekelwe kolu lwazi, ugqirha wakho uya kugqiba ukuba eli yeza lifanelekile kuwe okanye ukuba kufuneka kutshintshwe idosi.
Ulisebenzisa njani kanye kanye eli yeza?
Eli yeza lidla ngokuza njengesisombululo somlomo, ngoko ke kubalulekile ukulandela le miyalelo.
- Linganisa ngokuchanekileyo: Sebenzisa icephe okanye indebe ekhethekileyo eza neyeza ukuze ulilinganise. Musa ukulinganisa ngeetispuni okanye iipuni oziphetheyo ekhaya, kuba azichanekanga kangako. Ukuba awunayo indlela yokufumana icephe elikhethekileyo, buza ugqirha wakho okanye ikhemisti ngalo mba.
- Yithathe ngexesha:Thatha amayeza ngamaxesha athile amiselweyo, njengoko ugqirha wakho ekuyalele. Eli yeza lidla ngokunikwa malunga neyure ngaphambi kokuba ufumane i-chemotherapy okanye unyango lwe-radiation.
- I-Overdose: Ungaze uthathe ngaphezu kwedosi echazwe ngugqirha wakho. Ukuba ucinga ukuba ngempazamo uthathe amayeza amaninzi kakhulu, fowunela iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko okanye uye kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane.
Ukuba unika abantwana eli yeza...
Eli yeza lifuna unonophelo olukhethekileyo xa linikwa abantwana. Ngoko ke, thetha nogqirha wabantwana kwaye ulisebenzise kuphela ngokwengcebiso yakhe.
Khumbula, eli yeza limiselwe wena wedwa . Ungaze unike omnye umntu iyeza lakho, nokuba iimpawu zakhe ziyafana.
Ngaba kukho iingxaki ngamanye amayeza? (Ukusebenzisana kwamayeza)
Ewe, iGranisetron inokunxibelelana namanye amayeza owasebenzisayo. Kungoko ke, kubaluleke kakhulu ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini kunye namayeza esintu) . Lumka ngakumbi ngamayeza adweliswe ngezantsi.
| Amayeza angafanele asetyenziswe ngeGranisetron | |
|---|---|
| Uhlobo lweyeza | Imizekelo |
| Izinto ezilwa nokungunda | NjengeFluconazole, iItraconazole, neKetoconazole |
| Amayeza achaphazela isigqi sentliziyo | ICisapride, iDronedarone, iPimozide, iThioridazine |
| Ukuba usebenzisa la mayeza, thetha nogqirha wakho. | |
| Amayeza okudakumba | Iindidi ezahlukeneyo zemithi yokunciphisa uxinezeleko |
| Iipilisi zokubulala iintlungu ezinamandla | IFentanyl, iTramadol |
| Okunye | I-Linezolid (i-antibiotic), ii-MAOI, i-Methylene blue, i-Phenobarbital, namanye amayeza andisa ixesha le-QT yentliziyo |
Olu luhlu aluphelelanga. Ngoko ke xelela ugqirha wakho ngazo zonke iziyobisi ozisebenzisayo, nokuba uyatshaya, usela utywala, okanye usebenzisa ezinye iziyobisi .
Zithini iziphumo ebezingalindelekanga ezinokubakho xa usebenzisa amayeza?
Njengayo nayiphi na iyeza, iGranisetron inokubangela ezinye iziphumo ebezingalindelekanga. Ezinye ziqhelekile kwaye ziyaphela kwiintsuku ezimbalwa. Kodwa ezinye zinokuba yingozi.
| Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ngoko nangoko | |
|---|---|
| ⚫ Ubunzima bokuphefumla, ukuphefumla kancinci | ⚫ Ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga |
| ⚫ Ukuba nesiyezi, ukuba nentloko ende, ukuquleka | ⚫ Ukuxhuzula |
| ⚫ Ukurhawuzelela kwesikhumba, ukurhawuzelela | ⚫ Ukudumba kobuso, ulwimi, umphimbo, amalungu omzimba |
| ⚫ Ukuziva uxinene esifubeni | ⚫ Ukubila kakhulu, ukungcangcazela |
| ⚫ Umkhuhlane kunye nokubanda | ⚫ Ukulahlekelwa yibhalansi |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| ⚫ Ukuqhinwa okanye urhudo | ⚫ Intloko ebuhlungu |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, thetha nogqirha wakho ngazo.
Uligcina njani iyeza?
- Gcina kude nokufikelela kwabantwana.
- Gcina kubushushu begumbi (phakathi kwe-15 kunye ne-30 degrees Celsius).
- Khusela ekukhanyeni ngqo.
- Lahla amayeza aphelelwe lixesha.
Umyalezo Wokuya Ekhaya
- I-Granisetron liyeza elibaluleke kakhulu elisetyenziselwa ukulawula isicaphucaphu kunye nokuhlanza okubangelwa lunyango lomhlaza (i-chemotherapy/radiation).
- Ngaphambi kokuba uqale amayeza, qiniseka ukuba uxelela ugqirha wakho ngazo zonke iimeko zakho zempilo kunye nawo onke amanye amayeza owasebenzisayo.
- Sebenzisa icephe okanye indebe ekhethekileyo eza neyeza ukulinganisa ulwelo. Musa ukusebenzisa icephe onalo ekhaya.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu ezifana nobunzima bokuphefumla, utshintsho kwisantya sentliziyo, ukuxhuzula, okanye ukudumba komzimba, funa ingcebiso kagqirha ngoko nangoko okanye uye kwi-ETU.
- Eli yeza lelakho wedwa. Ungaze ulinike omnye umntu.
- Ukuba unemibuzo engaphezulu malunga nale yeza, ungathandabuzi ukubuza ugqirha wakho.
👩🏽⚕️ Imibuzo eyongezelelweyo (Ii-FAQ)
💬 Iipilisi/ugonyo lweGranisetron (Granisetron / Sancuso, Kytril) zisetyenziselwa siphi isifo?
Oku akufani neDomperidone, oyithathayo ukuze uyeke ukuhlanza! Eli liyeza elinamandla kakhulu (i-5-HT3 receptor antagonist / Antiemetic) lokulwa nesicaphucaphu kunye nokuhlanza emhlabeni. Linikwa ngokukodwa izigulana ezinomhlaza (iChemotherapy/Radiation) emva kwechemotherapy, nasemva kotyando olukhulu, ukuthintela i-100% yesicaphucaphu esinzima kunye nokuhlanza esingenakukuthwala kwaye amathumbu/amathumbu aphuma.
💬 Eli yeza linamandla (iGranisetron) lifikelela njani engqondweni yethu kwaye liyeke ukuhlanza kakhulu?
Xa amayeza e-chemotherapy, afana namayeza e-chemotherapy, engena emzimbeni, amathumbu akhupha inani elikhulu lekhemikhali ebizwa ngokuba yi-'Serotonin (5-HT).' Loo khemikhali iya 'kwiziko lokuhlanza (CTZ)' engqondweni ize ibangele ukuhlanza ngokungathi ucinezela iqhosha. Kwangoko nje eli yeza lingena emzimbeni, 'ii-serotonin receptors (5-HT3)' emathunjini nasebuchotsheni zivalekile/zivalekile ngokupheleleyo (i-Serotonin blockade). Ekubeni kungekho ndlela yokuba umyalezo udlule, isigulane asihlanzi.
💬 Zeziphi iingozi ekufuneka abantu abasebenzisa eli yeza lokulwa nokugabha (iGranisetron) baziqaphele?
Eyona miphumo mibi kakhulu neyicaphukisayo kukuba iyayicothisa kancinci indlela yokuhambisa amathumbu, nto leyo enokubangela 'ukuqunjelwa kakhulu' kunye nentloko ebuhlungu kakhulu. Enye ingozi ebulalayo kukuba inokubangela 'i-QT Prolongation / Severe arrhythmias' (ingakumbi kubantu abaneengxaki zentliziyo), enokutshintsha isigqi sombane sentliziyo kwaye ibangele ukubetha kwentliziyo okungaqhelekanga/okukhawulezileyo, ngoko ke ugqirha uya kujonga rhoqo i-ECG/EKG.
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