Mhlawumbi ukhe waliva igama elithi "ukudumba" kakhulu, akunjalo? Mhlawumbi silisebenzisa eli gama xa sifumana isilonda, inxeba lidumba libe bomvu, okanye sifumana umkhuhlane. Ngokwenene yindlela eqhelekileyo yokusabela kwenkqubo yethu yokuzikhusela. Kodwa ubusazi ukuba ngamanye amaxesha le meko yokudumba inokuhlala ixesha elide emizimbeni yethu ngaphandle kokwenzakala okanye usulelo olubonakalayo? Oku sikubiza ngokuba kukudumba okungapheliyo . Namhlanje siza kuthetha ngesihloko esibalulekileyo kubantu abaninzi: ngaba kukho unxibelelwano phakathi kokudumba okungapheliyo kunye nomhlaza webele?
Okokuqala, yintoni le nto yokudumba?
Ngamafutshane, ukudumba yindlela umzimba osabela ngayo kwingozi, njengosulelo okanye inxeba. Khawuthelekelele usika umnwe wakho. Indawo ejikeleze inxeba ibomvu, idumbile kancinci, kwaye ivakalelwa kukufudumala, akunjalo? Oko kukudumba okubukhali. Oko kuthetha ukuba "umkhosi" womzimba wakho (iiseli zomzimba) ufikile kwindawo yenxeba, walwa neentsholongwane ezihlaselayo, waza waqala ukuphilisa inxeba. Le yinto elungileyo, kwaye iza kuphela kwiintsuku ezimbalwa.
Nangona kunjalo, ukudumba okungapheliyo yinto eyahlukileyo. Kukudumba okuphantsi okuqhubeka kwenzeka emizimbeni yethu kangangeenyanga, kwaneminyaka. Kunokubangelwa zezi zinto zilandelayo:
- Usulelo olungalawulwayo
- Ukutyeba kakhulu (ubunzima bomzimba obandayo)
- Ubomi bobuvila ngaphandle kokuzilolonga
- Ukusetyenziswa kotywala kunye necuba
- Uxinzelelo olungapheliyo
Oku kuvutha okungapheliyo, njengento ehlala ivutha kwilangatye eliphantsi, kungonakalisa iiseli zethu kancinci kancinci, kwaye ekuhambeni kwexesha, kuvule indlela yezifo ezinzulu ezifana nomhlaza.
Yintoni enxulumene nomhlaza webele kunye nokudumba oku?
Le yingongoma efumana ingqwalasela enkulu kubaphandi bezonyango okwangoku. Nangona kungekabikho sigqibo siqinisekisiweyo ngokupheleleyo ngale nto, ubungqina obuqinileyo buyaqokelelwa.
"Le yingongoma enzima kakhulu. Ndicinga ukuba ukudumba kudlala indima ekuphuhliseni nasekusasazekeni komhlaza, kungekuphela nje komhlaza webele," utshilo uGqr. Naoto Tada Ueno, ingcali kwi-MD Anderson Cancer Center.
Nazi ezinye zezinto ezifunyenweyo kolu phando:
- Umngcipheko wokuphinda ube nomhlaza webele emva konyango ngenxa yokuvuvukala okungapheliyoInganda.
- Ezinye izifundo zibonise ukuba abantu abasebenzisa amayeza angengo-steroidal anti-inflammatory (NSAIDs) (umz., ibuprofen, iaspirin) banomngcipheko omncinci wokuba nomhlaza webele. (Kodwa musa ukuqala oku ngaphandle kokubuza ugqirha wakho, kulungile?!)
- Oku kuqaqanjelwa okungapheliyo kunokubangela ukusasazeka kweeseli zomhlaza kwaye kunciphise impendulo kunyango lomhlaza.
Kodwa iingcali zithi ingaba ukulawula ukudumba kukodwa kungayekisa ukusasazeka komhlaza kwaye kwandise ubomi “kusengumbuzo omkhulu.” Isayensi isazama ukuqonda kakuhle indlela oku kusebenza ngayo oku.
Ukuzikhusela komzimba kunye ne-microbiome yomzimba wethu zinxulumene njani noku?
Eli bali liza nzulu kancinci. Linomdla kakhulu. Besitshilo ngaphambili ukuba ukudumba ngumsebenzi wenkqubo yethu yokuzikhusela komzimba. Ngoko ke ezinye izazinzulu zicinga ukuba unobangela wolu qhagamshelo lokuvuvukala nomhlaza usenokuba ngumsebenzi wenkqubo yethu yokuzikhusela komzimba.
Uphononongo olwenziwe ngabaphandi kwiKliniki yaseMayo lufumene into emangalisayo. Oko kukuthi, kukho iintlobo ezahlukeneyo zeebhaktheriya kwizicubu zebele zabasetyhini abasempilweni abangenayo umhlaza nakwizicubu zebele zabasetyhini abanomhlaza. Oku kuthetha ukuba njengamathumbu ethu, izicubu zebele zinoluntu lwazo lweentsholongwane (i-microbiome) .
Okumangalisayo kukuba uluntu lweentsholongwane emabeleni abafazi abanomhlaza lwalwahlukile kolwabasetyhini abasempilweni. Ekubeni iintsholongwane zinokulawula izinga lokudumba emizimbeni yethu, izazinzulu zicinga ukuba lo mahluko usenokuba yibhulorho phakathi komngcipheko womhlaza webele kunye nokudumba.
Ukubaluleka kwale "microbiome" kukhulu kangangokuba kufumaniseke ukuba uluntu lweentsholongwane ezisemathunjini abantu abasabela kakuhle kunyango lwe-immunotherapy olunikwa izigulane zomhlaza lwahlukile kolwabo bangaphenduliyo. Ke ngoko, izazinzulu ngoku ziphanda ukuba iindlela ezifana "nokufakelwa kwendle" zinokutshintsha na "microbiome" yomntu kwaye zonyuse impumelelo yonyango lomhlaza. Nangona ezi zisesezigabeni zokuqala, zinokwenza umahluko omkhulu kunyango lomhlaza kwixesha elizayo.
Ngoko ke singakunciphisa njani oku kuqhambuka okungapheliyo?
"Ukuba ubuza ukuba kukho na iyeza elithile okanye indlela ethile eqinisekisiweyo ukuba iyasebenza, impendulo okwangoku 'nguhayi,'" utshilo uGqr. Ueno oyingcali. Kodwa uthi masingakhathazeki, siza kufunda okungakumbi ngale nto kwiminyaka elishumi ezayo.
Kodwa asinakulinda nje de kube ngoko. Ngethamsanqa, ukwenza utshintsho oluncinci kwindlela esiphila ngayo kunokunceda kakhulu ekulawuleni oku kuqhambuka okungapheliyo. Ezi zinto azinakunciphisa nje umngcipheko wakho wokuba nomhlaza, kodwa zikwanceda ekukhuseleni kwezinye izifo ezininzi, ezifana nesifo seswekile nesifo sentliziyo.
Jonga itheyibhile engezantsi ukuze ubone ukuba singenza ntoni.
| Okufanele ukwenze (Ukutshintsha Indlela Yokuphila) | Kutheni kubalulekile? (Kutheni Kunceda) |
|---|---|
| Ukugcina ubunzima obusempilweni | Ukutyeba kakhulu yeyona nto iphambili ekudumbeni okungapheliyo. Xa utyeba, uba nokunganyamezelani ne-insulin , nto leyo enyusa amanqanaba eswekile egazini kunye nokudumba. |
| Ukuzilolonga rhoqo | Enye indlela entle yokunciphisa ukudumba kukwenza ubuncinci imizuzu engama-30 yokuzilolonga okuphakathi (njengokuhamba ngokukhawuleza okanye ukukhwela ibhayisekile) ngemini. |
| Ukuthintelwa kotywala | Ukusela iziselo ezingaphezu kwesinye ngosuku kubafazi nezimbini kumadoda kwandisa ukudumba. Utywala bukwanyusa umngcipheko wokuba nomhlaza wamabele. |
| Ukuyeka ukutshaya | Iikhemikhali ezikwicuba ziye zabonakaliswa kakuhle ukuba zibangela ukudumba emzimbeni, ngoko ke esi sesinye isizathu esihle sokuyeka ukutshaya. |
| Ulawulo lwezifo ezingapheliyo | Ukuba uneengxaki zempilo ezifana nesifo seswekile okanye izifo ezibangelwa kukuzikhusela komzimba, zilawule. Bona ugqirha wakho rhoqo kwaye uthathe amayeza akho njengoko uyalelwe. |
| Ulawulo loxinzelelo | Uxinzelelo olude lunyusa ukudumba. Zama ukuphumla ngezinto ezifana neyoga, ukucamngca, ukuhambahamba nomhlobo, ukumamela umculo, okanye ukubhala kwincwadi yemihla ngemihla. |
Umyalezo Wokuya Ekhaya
- Kukho iintlobo ezimbini zokudumba: ukudumba okwenzeka xa kukho ukwenzakala nje (ukudumba okukhulu) kunye nokudumba okuhlala emzimbeni ixesha elide (ukudumba okungapheliyo). Kukudumba okungapheliyo okuyingozi kuthi.
- Nangona kukho ubungqina obuqinileyo bokuba kukho unxibelelwano phakathi kokudumba okungapheliyo kunye nomhlaza wamabele, uphando ngale ndlela luyaqhubeka.
- Eyona ndlela ilungileyo yokulawula oku kudumba kukugcina indlela yokuphila esempilweni. Ukugcina ubunzima obusempilweni, ukuzilolonga, ukutya ukutya okunempilo, kunye nokuphepha ukutshaya notywala kubaluleke kakhulu.
- Ukuba unemibuzo okanye unemibuzo malunga nomhlaza webele okanye nayiphi na enye ingxaki yempilo, nceda ungathembeli kulwazi olukwi-intanethi kuphela, kodwa qhagamshelana nogqirha wakho wosapho ukuze ufumane ingcebiso echanekileyo.
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