Ingaba unamanqanaba aphezulu e-phosphate emzimbeni wakho? Masithethe nge-hyperphosphatemia!

Ngaba wakha wazibuza ukuba kutheni ngamanye amaxesha izinto ezithile emizimbeni yethu ziphezulu kunokuba kufanele zibe njalo? Mhlawumbi ugqirha ukuxelele ukuba une-phosphate eninzi egazini lakho. Okanye mhlawumbi ukhe weva ngayo ndaweni ithile. Oku sikubiza ngokuba yi-hyperphosphatemia. Nangona eli gama lisenokuvakala lingaqhelekanga, ukuba siliqonda ngokuchanekileyo, akukho nto ibalulekileyo yokulixhalabela.

Yintoni kanye kanye i-hyperphosphatemia?

Ngamafutshane, i-hyperphosphatemia iyenzeka xa igazi lakho lineminerali eninzi ebizwa ngokuba yi-phosphate. I-phosphate sisondlo esibalulekileyo emizimbeni yethu. Inceda ukugcina amathambo namazinyo ethu eqinile, inika amandla kwiiseli zethu, kwaye inceda ekwenzeni ii-membrane zeeseli.

Cinga ngale ndlela, i-phosphate ifana nebhetri encinci emzimbeni wethu. Ukuze ezi zisebenze kakuhle, kufuneka zibe netshaja yombane. I-Phosphate yenye ye-electrolyte ezinjalo. Ii-electrolyte ziiminerali ezinokuthi zithathe itshaja yombane elungileyo (+) okanye engalunganga (-) xa zinyibilikisiwe emanzini okanye kulwelo olufana negazi lethu. Ngoko ke, ukugcina eli nqanaba le-phosphate lilungelelene kubalulekile kwimisebenzi emininzi emzimbeni. Uyaqonda?

Ngubani onokuba nethuba elikhulu lokufumana le meko?

Enyanisweni, nabani na unokuba nale meko ibizwa ngokuba yi-hyperphosphatemia. Nangona kunjalo, ixhaphake kakhulu kubantu abaneengxaki zezintso. Ngokukodwa, abantu abanesifo sezintso esinganyangekiyo (CKD) , ingakumbi abo banesifo esiqhubekekayo, okanye abo banesifo sezintso, banamathuba amaninzi okuba nale meko.

Ngoku, kukho izinto ezinokubangela isifo sezintso. Ukuba unenye okanye ngaphezulu kwezi zilandelayo, usemngciphekweni omncinci wokufumana isifo sezintso, kwaye ngenxa yaso, i-hyperphosphatemia:

• Ukuba unesifo seswekile (iDiabetes Mellitus) .
• Ukuba unesifo soxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi oluphezulu) .
• Ukuba unesifo sentliziyo .
• Ukuba kukho umntu kusapho lwakho oye waba nesifo sezintso (oko kuthetha ukuba sisenokuba sisifo sofuzo).
• Ukuba kukho into engaqhelekanga kwindlela ezimile ngayo izintso zakho.
• Ukuba ungumntu wase-Afrika-Amerika, waseHispanic, wase-Asia, okanye wase-Native American (abantu abakula maqela eentlanga banamathuba amaninzi okufumana isifo sezintso).
• Ukuba uneminyaka engaphezu kwama -60 ubudala .
• Ukuba ubusoloko usebenzisa amayeza okunciphisa iintlungu ixesha elide , ingakumbi amayeza angengo-steroidal anti-inflammatory (NSAIDs), anokuthengwa kwivenkile yezonyango.

Ixhaphake kangakanani le meko?

Ukuba ujonga uninzi lwabantu ehlabathini, kunqabile ukuba ne-hyperphosphatemia yodwa. Oko kuthetha ukwanda kwe-phosphate egazini. Kodwa, njengoko benditshilo ngaphambili, ukuba unesifo sezintso esinganyangekiyo , ingakumbi ukuba sibi kakhulu, esi sifo sixhaphake kakhulu. Xa sithetha nje, malunga nama-70% abantu abanesifo sezintso esinganyangekiyo baye bafunyanwa bene-hyperphosphatemia.

Kwenzeka ntoni emzimbeni xa amanqanaba e-phosphate enyuka?

Besithethe ngaphambili ngendlela i-phosphate enceda ngayo ukuqinisa amathambo namazinyo ethu, inika amandla kwiiseli, kwaye inceda ekwakheni ii-membranes zeeseli. Yiyo loo nto. Kodwa, njengayo nayiphi na into, ukuba ininzi kakhulu kunokubangela iingxaki.

Khawucinge nje, ukuba inqanaba le-phosphate egazini lakho liphezulu kakhulu, liqala ukukhupha i-calcium emathanjeni akho. Kwenzeka ntoni emva koko? Amathambo aba buthathaka aze aqhekeke.

Ayipheleli apho, kodwa le phosphate igqithisileyo inokubangela ukuba kubekho iidiphozithi zecalcium emehlweni akho, emiphungeni, entliziyweni, nakwimithambo yegazi. Oku kuyingozi kancinci. Kuba ngokuhamba kwexesha, ezi diphozithi zonyusa umngcipheko wakho wokuhlaselwa sisifo sentliziyo, isifo sohlangothi , kwanokufa.

Zithini iimpawu zeHyperphosphatemia?

Ixesha elininzi, xa une-hyperphosphatemia kuphela, awuboni zimpawu zibalulekileyo. Oko kuthetha ukuba usenokungazi ekuqaleni ukuba une-phosphate eninzi emzimbeni wakho. Nangona kunjalo, njengoko besitshilo, xa le phosphate isanda, inokubangela ukuba i-calcium ilahleke emathanjeni nasegazini lakho. Oko kubizwa ngokuba yi -hypocalcemia . Oko kuthetha ukwehla kwenqanaba le-calcium egazini.

Ngoko ke, uninzi lwexesha, iimpawu ze-hyperphosphatemia ziyafana nezo zibangelwa yi-hypocalcemia. Jonga ukuba ezi mpawu zivakala ziqhelekile na kuwe:

• Ukuqaqamba kwemisipha.
• Izipikili ezithambileyo.
• Ulusu olomileyo.
• Iinwele ezirhabaxa kuneenwele zakho eziqhelekileyo.
• Iingxaki zememori .
• Ukucaphuka.
• Ukurhawuzelela emilebeni, elulwimini, kwiminwe, kunye/okanye ezinyaweni.
• Ngamanye amaxesha kuza njengokuxhuzula (ukuxhuzula).
• Ukungaqheleki kwentliziyo, oko kukuthi, i-arrhythmia.

Kutheni kukho i-hyperphosphatemia?

Kunokubakho izizathu ezahlukeneyo zoku. Ezona ziphambili zezi:

• Isifo sezintso esingapheliyo esiqhubekekayo. Esi sesona sizathu sixhaphakileyo. Xa izintso zingasebenzi kakuhle, azikwazi ukukhupha i-phosphate egqithisileyo emzimbeni.
• I-Hypoparathyroidism. Le yimeko apho amadlala e-parathyroid evelisa i-hormone encinci kakhulu ye-parathyroid, elawula amanqanaba e-calcium kunye ne-phosphate emzimbeni.
• I-pH yegazi lakho iphantsi kunesiqhelo (oko kuthetha ukuba igazi lakho line-asidi engaphezulu). Oku kusenokuba kungenxa yokuba imiphunga yakho ayikwazi ukukhupha yonke i-carbon dioxide eveliswa emzimbeni wakho. Oku kubizwa ngokuba yi -respiratory acidosis .
• Ukwehla kwe-pH yegazi ngenxa yezinye izizathu ( i-metabolic acidosis ).

Ukongeza kwezi, nangona zingaqhelekanga, i-hyperphosphatemia inokwenzeka ngenxa yezizathu ezilandelayo:

• I-ketoacidosis enxulumene nesifo seswekile.
• Ukonakala kwemisipha ( i-rhabdomyolysis ).
• Usulelo oluqatha ( sepsis ).
• Ukwenzakala kokutyumza (ukulimala okubangelwa yinto enzima ewela emzimbeni okanye yinto ecinezela umzimba ixesha elide).
• Umzimba wakho awuphenduli kakuhle kwi-hormone ye-parathyroid ( i-pseudohypoparathyroidism ).
• Ukungenisa i-phosphate eninzi emzimbeni wakho, nokuba kukutya okutyayo okanye nge- enema .

Yintoni eyona nto ixhaphakileyo?

Njengoko benditshilo ngaphambili, eyona nto iphambili neyona ixhaphakileyo ye-hyperphosphatemia sisifo sezintso esingapheliyo esiqhubekekayo.

Ingaba esi sisifo esosulelayo?

Hayi, i-hyperphosphatemia ayisosifo esosulelayo. Awunakusisasaza kwabanye. Nangona kunjalo, kunqabile kakhulu, ukuba singene kwiintsapho ngenxa yezizathu zemfuza.

Oogqirha bayibona njani le nto?

Ugqirha angakuxelela ukuba une-hyperphosphatemia. Uza kuthatha imbali yakho yezonyango , enze uvavanyo lomzimba , aze akubuze ngeempawu zakho, ukutya kwakho, kunye namayeza owasebenzisayo. Ukuze ufumane ukuba angakanani na amanqanaba akho e-phosphate, kuya kufuneka uhlolwe igazi .

Ngexesha lovavanyo lwegazi, ugqirha okanye umongikazi uza kuthatha igazi elincinci kumthambo osengalweni yakho esebenzisa inaliti encinci (21 gauge, encinci kancinci kunencam yecici eliqhelekileyo). Le sampuli yegazi ithunyelwa kwilebhu ukujonga ukuba ingakanani na iphosphate egazini lakho. Ukuba inqanaba lakho lephosphate lingaphezulu kwe-4.5 milligrams nge-deciliter (4.5 mg/dL) yegazi,, oko kuthetha ukuba une-hyperphosphatemia.

Ukuba ufunyaniswe ukuba unale meko, ugqirha wakho unokuyalela uvavanyo olongezelelweyo ukujonga imeko yezintso zakho. Oku kungabandakanya:

• Uvavanyo lwegazi olongezelelweyo.
• Uvavanyo lokujonga iiproteni kumchamo.
• Iskeni ye-ultrasound .
• Iskeni ye-MRI .
• Iskeni ye-CT .
• i-biopsy yezintso ( ukuthatha iqhekeza elincinci lezicubu zezintso ukuze lihlolwe).

Zithini iindlela zonyango zoku?

Unyango lwe-hyperphosphatemia luxhomekeke kwinto ebangela ukwakheka kwe-phosphate egazini lakho. Ezinye ukutya kunye namayeza zinokubangela amanqanaba aphezulu e-phosphate. Ukuba oku kuyenzeka, kunokufuneka unciphise okanye uyeke ukutya ukutya okuthile okanye amayeza kwaphela. Okanye, unokufuna ukutshintshela kwelinye iyeza elinamanqanaba aphantsi e-phosphate.

Eyona nto ibalulekileyo kukulandela imiyalelo kagqirha ngokuchanekileyo.

Ugqirha wakho angakunika amayeza anciphisa ubungakanani be-phosphate efunxwa ngumzimba wakho. Oku kuthetha ukuba i-phosphate eninzi iphuma kumchamo wakho (umchamo). La mayeza aquka:

• Sevelamer (Sevelamer - RenaGel®)
• ILanthanum (iLanthanum - iFosrenol®)
• I-calcium acetate (iCalcium acetate - Calphron®)

Ukuba amanqanaba akho e-phosphate aphezulu ngenxa yokungasebenzi kakuhle kwezintso, ugqirha wakho angakuqalisa nge-dialysis . I-Dialysis yenza oko kufanele ukuba kwenziwe zizintso zakho. Oko kukuthi, isusa ulwelo olugqithisileyo kunye nenkunkuma, kuquka ne-phosphate, egazini lakho.

Zithini ukutya okune-phosphorus eninzi?

Kukho ukutya neziselo ezininzi ezine-phosphorus eninzi – into ekwenziwa kuyo i-phosphate. Kubalulekile ukuzazi ezi zinto, ingakumbi ukuba une-hyperphosphatemia.

• Iimveliso zobisi kunye nobisi, ezifana nobisi, itshizi ezicutshungulweyo, kunye neyogathi.
• Ezinye iziselo ezine-carbonated (iziphuzo ezine-soda pop/ezine-fizzy).
• Inyama elungisiweyo ( ezifana neesoseji kunye nebhekoni).
• Ukutya okukhawulezayo.
• Ukutya okulula ( izinto ezipakishwe kwiipakethe ezifana neetships, iibhisikithi).
• Amantongomane.
• Iinkozo ezipheleleyo , eziquka ingqolowa, i-oats, kunye nerayisi (ingakumbi ezo zine-bran).
• Iimbotyi.
• Iilentile.

Ugqirha wakho usenokuba ukuxeleleUza kuthunyelwa kwingcali yokutya kwezintso . Aba ngabantu abaziingcali kwindlela yokulawula ukutya kwakho ukuze baxhase impilo yezintso. Baza kukunceda wenze isicwangciso esikhethekileyo sokutya (ukutya kwezintso) esithintela ubungakanani be-phosphate emzimbeni wakho.

Ngaba ikho indlela yokuphuma kule meko?

Eyona ndlela ilungileyo yokuthintela i-hyperphosphatemia kukunyamekela impilo yezintso zakho kwaye uqaphele ubungakanani be-phosphate kunye ne-calcium oyityayo. Ukuba ucinga ukuba usenokuba semngciphekweni wale meko, thetha nogqirha wakho. Angakuthumela kwi -nephrologist . I-nephrologist ngugqirha ogxile kwiimeko ezichaphazela izintso.

Ngawaphi amaxesha afanelekileyo okubonana nogqirha?

Ukuba uyazi ukuba une-hyperphosphatemia, kwaye ubonakalisa iimpawu zesifo sezintso okanye ukungasebenzi kakuhle kwezintso, bona ugqirha ngoko nangoko. Musa ukulibazisa.

Yeyiphi imibuzo omele uyibuze ugqirha?

Xa usiya kugqirha, kubaluleke kakhulu ukubuza le mibuzo:

• Ungazi njani ngokuqinisekileyo ukuba ndine-hyperphosphatemia?
• Ukuba andinaso esi sifo, zeziphi ezinye iimeko zempilo endinokuba nazo?
• Ithini inqanaba le-phosphate egazini elisempilweni?
• Ngawaphi amayeza ondicebisa wona?
• Ngaba udinga i-prescription ukuze ufumane elo yeza, okanye ungalithenga nje kwikhemesti?
• Zeziphi ukutya neziselo endingafanele ndizitye?
• Ndingakanani i-phosphorus endifanele ndiyitye ngosuku?
• Ungandithumela kwingcali yokutya kwezintso?
• Ngaba kufuneka ndidibane nogqirha wezifo zengqondo okanye omnye umntu ochwephesha?

Yintoni umahluko phakathi kweHyperphosphatemia kunye neHypocalcemia?

Ezi zimbini zingadida kancinci, ngoko masicacise.

I-Hyperphosphatemia ibangelwa kukuba inqanaba le-phosphate egazini lakho liphezulu kakhulu .

I-Hypocalcemia kuxa amanqanaba e-calcium egazini lakho ehla kakhulu .

Ixesha elininzi, le meko ibizwa ngokuba yi-hypocalcemia yenzeka njengesiphumo esingesihle senye imeko yezonyango. I-Hyperphosphatemia yenye yezona zinto zibangela i-hypocalcemia.

Umyalezo Wokugqibela Wokuya Ekhaya

Kulungile, ngoko ke sithethe kakhulu nge-hyperphosphatemia. Ngamafutshane, kukunyuka kwenqanaba le-phosphate egazini lakho. Nangona ingaqhelekanga kakhulu kubantu abaninzi emhlabeni, inokuba yinto eqhelekileyo kubantu abanesifo sezintso esingapheliyo okanye ukungasebenzi kakuhle kwezintso .

Amaxesha amaninzi, akukho zimpawu zithile ekuqaleni. Ngenxa yoko, abantu abaninzi bayazi ukuba banale meko emva kokuba ezinye iimpawu zivele, mhlawumbi njenge-hypocalcemia.

Xa ufumanisa ukuba une-hyperphosphatemia, ingakumbi xa uxelelwa ukuba udinga i-dialysis, kuyinto eqhelekileyo ukuba nexhala kwaye uyoyika. Akukho nto imbi ngokuba neemvakalelo ezinjalo. Thetha nogqirha wakho ngayo nayiphi na imibuzo okanye iinkxalabo onazo. Baza kuphendula imibuzo yakho, bakunike inkxaso oyifunayo, kwaye bakunike iingcebiso zendlela yokujongana nale meko. Khumbula, awuwedwa!

I- Hyperphosphatemia, i-Phosphate, Isifo sezintso, Isifo sezintso esingapheliyo, i-Hypocalcemia, i-Dialysis