Ngaba ngequbuliso ulahlekelwe kukuva uze uzive unesizungu? Ngaba uva nje ingxolo ezindlebeni zakho? Nangona ucinga ukuba ezi zizinto eziqhelekileyo, ngamanye amaxesha emva kwezi zinto kunokubakho isifo esingazivanga kangako ngaso, kodwa kufuneka siqaphele. Namhlanje sithetha ngesifo esinjalo. Esi sifo yiNeurofibromatosis Type 2, okanye iNF2 ngamafutshane.
Ngamafutshane, yintoni i-Neurofibromatosis Type 2 (NF2)?
I-NF2 yimeko yemfuza echaphazela inkqubo yethu yemithambo-luvo. Ibangelwa lutshintsho kwimfuza elawula ukukhula kweeseli emizimbeni yethu. Olu tshintsho lwemfuza lubangela ukuba umzimba uvelise iiseli ezininzi kakhulu. Ezi seli zigqithisileyo zinokuqokelelana kwaye zenze iithumba.
Kodwa ungakhathazeki, uninzi lwala maqhuqhuva alunabungozi , oko kuthetha ukuba awanawo umhlaza. La maqhuqhuva akheka ikakhulu ku:
- Imithambo-luvo ejikeleze umzimba yimithambo-luvo efikelela kwiindawo zomzimba wethu, njengamalungu omzimba.
- I-membrane phakathi kwentloko yethu kunye nengqondo (i-meninges).
- Umqolo.
- Imithambo-luvo edibanisa ingqondo nendlebe yangaphakathi, enceda ekuveni nasekulinganiseni umzimba.
I-NF2 yimeko ekwiqela lezifo ezibizwa ngokuba yi-Neurofibromatosis. Eli qela lezifo lichaphazela kakhulu ulusu lwethu kunye nenkqubo yemithambo-luvo.
Ixhaphake kangakanani le meko ye-NF2 kuluntu?
Esi sisifo esingaqhelekanga. Ngokwezibalo, i-NF2 ichaphazela malunga nesinye kwiintsana ezingama-33,000 ezizelwe kwihlabathi liphela. Malunga ne-3% yazo zonke izigulana ezifunyaniswe zine-neurofibromatosis zizigulana ze-NF2.
Zithini iimpawu ze-NF2?
Iimpawu ze-NF2 zingahluka kumntu nomntu. Zixhomekeke ekubeni iithumba zikuphi emzimbeni wakho kwaye zikhulu kangakanani. Uninzi lwabantu luqala ngokufumana iimpawu ezibangelwa ziithumba kwimithambo-luvo edibanisa indlebe nengqondo.
Makhe sijonge ezi mpawu ukuze siziqonde kakuhle:
| Udidi lweempawu | Iimpawu eziqhelekileyo |
|---|---|
| Iimpawu zokuqala ezinxulumene ne-auditory nerve | |
| Iingxaki zokulinganisela | Isiyezi ngequbuliso |
| Ubunzima bokuva | Ukulahlekelwa kancinci kancinci kokuva |
| Ukukhala ezindlebeni | Ukuva isandi esikhalayo ezindlebeni (Tinnitus) |
| Ezinye iimpawu ze-neurological | |
| Ezinye iimpawu |
|
Iimpawu zihlala ziqala ukubonakala phakathi kobuntwana kunye neminyaka engama-30 ubudala. Kodwa le meko inokuchaphazela nabani na kuyo nayiphi na iminyaka. Kubantu abadala, imithambo-luvo edibanisa indlebe nengqondo idla ngokuchaphazeleka kuqala. Yiyo loo nto iingxaki zokuva ziqala ukubonakala. Nangona kunjalo, ebantwaneni, amathumba adla ngokukhula engqondweni okanye emgogodleni. Ukuba iimpawu zivela ebuntwaneni okanye ebusheni, oko kunokubonisa ukuba esi sifo sibi kakhulu.
Ziziphi iintlobo zeethumba ezikhula kwi-NF2?
Kukho iintlobo ezininzi ezahlukeneyo zeethumba ezinokuvela kwi-NF2. Makhe sizijonge ngokukhawuleza.
| Uhlobo lwethumba | Kalula nje... |
|---|---|
| I-Schwannomas | Ezi ziithumba zenkqubo yemithambo-luvo ezikhula kwiiseli ezibizwa ngokuba yiSchwann. Zihlala zikhula kwimithambo-luvo edibanisa ingqondo nendlebe yangaphakathi (i-vestibular schwannomas). Zingakhula nakwimithambo-luvo elawula intshukumo yamehlo, intshukumo yolwimi, kunye nokuginya. |
| IiMeningiomas | Uhlobo lwethumba oluvela kwi-membrane ekhuselayo (i-meninges) phakathi kwengqondo kunye ne-skull. |
| IiGliomas | Ezi luhlobo lwethumba lobuchopho elivela kwiiseli ezibizwa ngokuba zii-glial cells. Zihlala zenzeka zijikeleze imithambo-luvo ye-optic. |
| Ii-Ependymomas | Olu luhlobo lwe-glioma. Lukhula engqondweni nasemgogodleni. Luvela kwiiseli ezenza ulwelo lwe-cerebrospinal (CSF) engqondweni nasemgogodleni. |
Kutheni i-NF2 ikhula? Yintoni unobangela?
Isizathu esiphambili soku kukutshintsha kwejini ebizwa ngokuba yiNeurofibromin 2 (NF2) emzimbeni wethu. Le jini inceda ekwenzeni iproteni ebizwa ngokuba yi-'merlin'. Umsebenzi ophambili wale proteni kukuyeka ukukhula kwee-tumor. Oko kuthetha ukuba icinezela i-tumor .
Ngoko ke, xa kukho isiphene kule gene ye-NF2, iproteni 'yeMerlin' ayiveliswa kakuhle. Emva koko ezinye iiseli emzimbeni wethu ziyahlukana ngokungalawulekiyo, ziphindaphindeke, zize zihlangane ukuze zenze amathumba.
Olu tshintsho lwemfuza lunokufunyanwa kubazali ukuya kubantwana. Oku kubizwa ngokuba yi-autosomal dominant pattern. Kodwa kubantu abaninzi, aluyomfuza. Oku kuthetha ukuba olu tshintsho lwemfuza lunokubakho nasekukhulelweni, ngaphandle kwembali yosapho.
Ziziphi iingxaki ezinokwenzeka ngenxa yale meko?
Ukuba i-NF2 ayilawulwa, ezinye iingxaki zinokubakho. Ezi ziquka:
- Ukulahlekelwa ngokupheleleyo kukuva
- Ukulahlekelwa ngumbono
- Umonakalo wemithambo-luvo ongapheliyo
- Ukwakheka kolwelo engqondweni (i-hydrocephalus)
Nangona ezi thumba zingengomhlaza, kukho ithuba elincinci lokuba ezinye iithumba ze-NF2 zinokuba ngumhlaza, kunqabile kakhulu. Ke ngoko, ukuvavanywa rhoqo ngugqirha kubaluleke kakhulu.
Ifunyaniswa njani i-NF2?
Xa usiya kugqirha, uza kuqala akuhlole kakuhle, akubuze ngeempawu zakho nokuba kukho umntu kusapho lwakho okhe waba nesi sifo na. Emva koko, angenza iimvavanyo ezininzi ukuqinisekisa ukuba unesifo:
- Iskeni se-MRI (Magnetic Resonance Imaging): Oku kunokubona ngokucacileyo iithumba kwinkqubo yemithambo-luvo kunye nolusu.
- Uvavanyo lokuva: Jonga inqanaba lokuva kwakho.
- Uvavanyo lwamehlo: Jonga ukuba akukho ngxaki yamehlo okanye ezinye iingxaki zamehlo.
- Uvavanyo lwe-genetic: Ukuqinisekisa ukuba kukho isiphene kwi-NF2 gene.
Ziziphi iindlela zonyango ze-NF2?
Akukho nyango loku okwangoku. Kodwa ungakhathazeki, ngoku kukho iindlela ezininzi eziphambili zokuxilonga, ukunyanga, kunye nokulawula ezi thumba. Ugqirha wakho uya kukhetha unyango olulungele wena. Iindlela zonyango zinokuhluka kumntu nomntu.
Nazi ezinye zeendlela eziphambili zonyango:
- Utyando: Ukususwa kweethumba ezinophawu ngotyando. Utyando lukwasetyenziselwa ukususa i-cataracts.
- Unyango lweKhemotherapy okanye iRadiation: Olu nyango lusetyenziselwa ukunciphisa ubukhulu bezinye iithumba. Unyango lwe-Stereotactic radiotherapy yenye yeendlela zonyango lweradiation eziphucukileyo.
- Izixhobo zokuncedisa ukuva nokubona: Abantu abanengxaki yokuva bangasebenzisa izixhobo ezifana 'nezixhobo zokuncedisa ukuva', 'ii-cochlear implants' okanye 'ii-auditory brainstem implants'. Izinto ezifana neeglasi zamehlo zinokunceda kwiingxaki zokubona.
- Ezinye izinto eziluncedo: Ukuba unengxaki yokulinganisela nokuhamba, ungasebenzisa izixhobo zokuhamba.
- Amayeza: Ugqirha unika amayeza okulawula iimpawu ezifana neentlungu.
Into ebalulekileyo kukuba ngamanye amaxesha, ukuba amaqhuqhuva awakubangeli ngxaki inkulu, ugqirha wakho unokugqiba ekubeni angawanyangi kodwa awajonge rhoqo. Kungoko ke, kubalulekile ukuba uhlolwe umzimba, uhlolwe i-MRI, kwaye uhlolwe iindlebe namehlo ubuncinane kanye ngonyaka.
Ndifanele ndibonane nogqirha nini?
Ukuba unenye okanye ngaphezulu kwezi mpawu zilandelayo, qiniseka ukuba ubona ugqirha.
- Utshintsho kwindlela ajonga ngayo.
- Ukutshintsha kwesandi okanye ukuvakala kweendlebe.
- Ubuthathaka bemisipha okanye ukugoba kobuso.
- Amaqhuma okanye amabala amatsha eluswini.
- Intloko ebuhlungu rhoqo.
- Intlungu emilenzeni ngaphandle kwesizathu.
- Ukuba nesithuthwane (ukuxhuzula).
Amaxesha amaninzi, utshintsho kwindlela yokuva okanye yokubona luphawu lokuqala lwesi sifo. Ngoko ke, ukuba ufumana naziphi na kwezi mpawu, funa ingcebiso kugqirha ngokukhawuleza.
Umyalezo Wokuya Ekhaya
- I-Neurofibromatosis Uhlobo lwesi-2 (NF2) yimeko yemfuza ebangela ukuba iithumba ezingezizo ezomhlaza zenzeke kwinkqubo yemithambo-luvo.
- Ukuva kancinci, isiyezi, kunye nokukhala kweendlebe (i-tinnitus) zezona mpawu ziqhelekileyo zokuqala.
- Nangona kungekho nyango lwesi sifo, zininzi iindlela eziphambili zokulawula iimpawu kunye nokunyanga amathumba.
- Emva kokuba isifo sifunyenwe, kubaluleke kakhulu ukuba phantsi kweliso likagqirha rhoqo, kuquka ii-MRI scans, ukuvavanywa kweendlebe namehlo, kunye nokuhlolwa rhoqo ubuncinane kanye ngonyaka.
- Ukuba wena okanye umntu osapho lwakho unezi mpawu, bonana nogqirha ofanelekileyo ngokukhawuleza ukuze akunike ingcebiso.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho