Xa wena okanye umntu omthandayo enikwa iyeza elitsha lomhlaza, kuyinto eqhelekileyo ukuba noloyiko kwaye ube nomdla. Kukho imibuzo emininzi efika engqondweni, efana nokuba loluphi uhlobo lonyango, lusebenza njani, kwaye yintoni ekufuneka uyilumkele. Namhlanje, siza kuthetha ngelinye lamayeza achasene nomhlaza, iPemigatinib. Emva kokufunda eli nqaku, uya kuba nokuqonda okungcono ngeli yeza.
Yintoni iPemigatinib?
Ngamafutshane, iPemigatinib lunyango olujoliswe kulo . Oko kuthetha ukuba ijolise kwaye ihlasele iiseli zomhlaza ngokukodwa, endaweni yokuchaphazela zonke iiseli emzimbeni njengamayeza amadala omhlaza.
Eli yeza linceda kakhulu:
- Ngomhlaza we-bile duct .
- Kwezinye iintlobo zomhlaza onxulumene nomongo wethambo (iMyeloid/Lymphoid Neoplasm) .
Cinga ngeeseli zomhlaza njengokhula. Ezi zityalo zifuna izondlo ezikhethekileyo (iproteni) ukuze zikhule. Oko kwenziwa liyeza iPemigatinib kukuthintela eso sondlo ukuba singafiki kwiiseli zomhlaza. Kufana nokucima umbhobho wamanzi ukuya kokhula. Emva koko iiseli zomhlaza zilahlekelwa okanye zinciphise kakhulu amandla azo okukhula nokusasazeka emzimbeni wonke. Uza kubona igama lophawu lwale chiza, iPemazyre .
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
Ngaphambi kokuba ugqirha wakho akunike eli yeza, kubalulekile ukwazi imbali yakho epheleleyo yempilo. Ngoko ke, ukuba unenye yezi meko zilandelayo, qiniseka ukuba wazise ugqirha wakho.
- Amanqanaba aphezulu e-phosphorus egazini: Eli yeza linokubangela ukuba amanqanaba e-phosphorus egazini anyuke, ngoko ke kubalulekile ukukwazi oku.
- Isifo sezintso: Izintso zifana nezihluzo emizimbeni yethu. Zinceda ekususeni amayeza emzimbeni. Ukuba kukho ingxaki ngezintso, ugqirha unokutshintsha umthamo wamayeza.
- Izifo zesibindi: Isibindi sisitho esibalulekileyo esibandakanyekayo kwimetabolism yeziyobisi emzimbeni.
- Iingxaki zamehlo: Eli yeza lisenokuchaphazela amehlo, ngoko ke ukuba sele unayo nayiphi na ingxaki yamehlo, nceda usazise kwangethuba.
- Ukunganyamezelani nePemigatinib okanye naliphi na elinye iyeza, ukutya, okanye idayi: Kubaluleke kakhulu ukusixelela ukuba ngaba ukhe waba nazo naziphi na ii-allergies ngaphambili.
- Ukuzama ukukhulelwa okanye ukukhulelwa okwangoku: Eli yeza linokuba yingozi kakhulu kumntwana ngexesha lokukhulelwa.
- Ukuncancisa: Eli yeza linokudluliselwa kumntwana ngobisi lwebele.
Ukunika ugqirha wakho ulwazi oluchanekileyo ngezi zinto kubaluleke kakhulu kukhuseleko lwakho kunye nempumelelo yonyango lwakho.
Indlela yokusebenzisa amayeza ngokuchanekileyo?
Ukuze ufumane amayeza akho aluncedo kakhulu, kubalulekile ukuwasebenzisa ngokuchanekileyo.
- Eli yeza lithathwa ngomlomo njengepilisi. Ziqhelise ukulithatha ngexesha elifanayo yonke imihla .
- Musa ukuphula, ukutyumza, okanye ukuhlafuna ithebhulethi. Ukwenza njalo kunokutshintsha indlela elisebenza ngayo iyeza. Ngoko ke, ginya ithebhulethi yonke ngamanzi.
- Ungayithatha ngaphambi okanye emva kokutya, kodwa ukuba uziva ngathi unesisu esibuhlungu, kungcono ukuyithatha kunye nokutya.
- Qhubeka usela amayeza de ugqirha wakho akuxelele ukuba uyeke. Nokuba ufumana iziphumo ebezingalindelekanga, ungayeki ukuwasela amayeza ngaphandle kokubonisana nogqirha wakho. Yena uza kulungisa umthamo okanye akucebise ukuba uyeke ukuwasela amayeza ukuba kuyimfuneko.
- Kubalulekile: Musa ukusela ijusi yegrapefruit ngelixa usela eli yeza. Ijusi yegrapefruit ingatshintsha indlela eli yeza elisebenza ngayo emzimbeni.
Ungenza ntoni ukuba uthatha amayeza amaninzi kakhulu?
Khawucinge ukuba uthathe amayeza angaphezu kwedosi emiselweyo. Ukuba oku kuyenzeka, ungoyiki. Tsalela umnxeba iZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko . Okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Kuthekani ukuba ndiphoswa ngamayeza am?
Khawucinge ukuba bekufanele ukuba usele amayeza akho ngo-8 kusasa. Ulibele ukuwasela.
- Ukuba uyakhumbula ngaphambi kwentsimbi ye-12 emini (oko kukuthi, zingadlulanga iiyure ezi-4), thatha ipilisi ngokukhawuleza nje ukuba ukhumbule.
- Kodwa ukuba uyakhumbula emva kwentsimbi ye-12 emini (oko kukuthi, emva kwexesha elingaphezulu kweeyure ezi-4), yityeshele ipilisi oyiphosileyo. Yisele kwakhona ipilisi ngosuku olulandelayo ngexesha eliqhelekileyo.
- Ungaze uthathe iipilisi ezimbini ngaxeshanye, nokuba kungenxa yokuba ulibele ukuthabatha enye okanye kuba kufuneka uthabathe enye.
Ziziphi ezinye izinto ezinokusebenzisana nale mithi?
Amanye amayeza, iivithamini, okanye iimveliso zezityalo ozisebenzisayo zinokusebenzisana nePemigatinib. Ngoko ke, xelela ugqirha wakho ngazo zonke iziyobisi ozisebenzisayo (kuquka iivithamini kunye neemveliso zezityalo) . Nazi ezinye izinto ekufuneka uzilumkele.
| Uhlobo lwamayeza/lokutya | Imizekelo |
|---|---|
| Amanye amayeza okubulala iintsholongwane | I-Erythromycin, iClarithromycin |
| Amanye amayeza okubulala iintsholongwane anikwa i-HIV okanye i-Hepatitis | Buza ugqirha. |
| Amanye amayeza osulelo lwefungus | I-Ketoconazole, i-Itraconazole |
| Amanye amayeza okunyanga isifo sokuwa | I-Carbamazepine, iPhenobarbital, iPhenytoin |
| Iimveliso zezityalo | I-St. John's Wort |
| Ukutya neziselo | Ijusi yegrapefruit |
Olu luhlu aluphelelanga, ngoko ke kungcono ukuxelela ugqirha wakho ngayo yonke into oyithathayo.
Izinto ekufuneka uzikhumbule xa usebenzisa amayeza
- Ukuhlolwa rhoqo kwezonyango: Musa ukulibazisa imihla yeklinikhi enikwa ngugqirha wakho. Olu vavanyo lubaluleke kakhulu ekujongeni inkqubela yonyango lwakho kunye nokulawula iziphumo ebezingalindelekanga. Ungacelwa ukuba wenze uvavanyo lwegazi.
- Utshintsho lwamehlo: Eli yeza linokubangela amehlo omileyo kunye nokubona okufipheleyo. Ukuba unxiba iilensi zokunxibelelana, unokufumana ukungakhululeki. Amathontsi amehlo aqatywayo angasetyenziswa kwiimeko ezinjalo . Nangona kunjalo , ukuba ufumana naluphi na utshintsho embonweni wakho (umbono ofipheleyo, amabala amnyama, okanye izinto ezibonakala ngathi ziyashukuma), yazisa ugqirha wakho ngoko nangoko.
- Ukuthintela ukukhulelwa: Le yingxaki ebaluleke kakhulu.
- Ukuba ungumfazi, kuphephe ukukhulelwa ngelixa usela eli yeza kwaye emva kweveki enye uyekile ukusebenzisa eli yeza.
- Ukuba uyindoda, sebenzisa ikhondom xa usabelana ngesondo ukuba iqabane lakho lingakhulelwa ngelixa lisela eli yeza kwaye iveki enye emva kokuyeka ukusebenzisa iyeza.
- Musa ukuncancisa xa usebenzisa eli yeza kwaye emva kweveki enye uyekile.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
Njengalo naliphi na iyeza, iPemigatinib inokubangela ezinye iziphumo ebezingalindelekanga. Ezinye zezi zinokuba yingozi, ngelixa ezinye ziqhelekile. Kubalulekile ukuzazi ezi zinto.
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha ngoko nangoko | |
|---|---|
| Iimpendulo ze-Allergic | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Utshintsho olukhulu emehlweni | Ukubona okufipheleyo, ukungaboni kakuhle, ukubona izinto ngokungathi zoluliwe, ukubona amabala amnyama okanye acwebezelayo. |
| Iimpawu ze-phosphorus ephezulu egazini | Ukuqhaqhazela okanye ukuqaqanjelwa yimisipha, iintlungu zamathambo okanye amalungu, ukungaziva mnandi emlonyeni. |
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ukuba ziyaqhubeka okanye ziyakhathaza | |
| Iziphumo ebezingalindelekanga eziqhelekileyo |
|
Indlela yokugcina nokulahla amayeza ngokukhuselekileyo?
- Indawo yokugcina: Gcina ibhotile yamayeza kude nabantwana nezilwanyana zasekhaya . Kungcono ukuyigcina kubushushu begumbi (phakathi kwama-20-25 degrees Celsius).
- Ukususwa:Kuphephe ukuphosa amayeza aphelelwe lixesha okanye angasetyenziswanga enkunkuma. Ukuze uwalahle ngokukhuselekileyo, susa iipilisi ebhotileni uze uzixube nento efana namagqabi eti asetyenzisiweyo, intlama yekofu, okanye umhlaba. Emva koko faka umxube kwibhegi evalwayo uze uwulahle kunye nenkunkuma. Ungaze uhlambe amayeza kwindlu yangasese nangasiphi na isizathu. Ukuba unemibuzo, buza ugqirha wakho.
Umyalezo Wokuya Ekhaya
- Sela amayeza kanye njengoko ugqirha wakho ekuyalele, ngexesha elifanelekileyo, kwaye ngokwedosi efanelekileyo. Ungaze utshintshe idosi ngokwakho.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi, iivithamini, kunye neemveliso zezityalo ozisebenzisayo.
- Musa ukusela ijusi yegrapefruit nangasiphi na isizathu ngelixa usebenzisa eli yeza.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu, ezinje ngokutshintsha kombono okanye umonakalo omkhulu wolusu, funa ingcebiso kagqirha ngoko nangoko.
- Kuphephe ukukhulelwa ngokupheleleyo ngelixa usela ipilisi kwaye iveki enye emva kokuba uyekile. Sebenzisa uhlobo lokuthintela ukukhulelwa oluthembekileyo.
- Nokuba uziva ungakhululekanga, kuphephe ukuyeka amayeza ngaphandle kokubonisana nogqirha wakho. Xoxa naye ngayo nayiphi na into ekuxhalabisayo.
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