Ngamanye amaxesha emva kokutya, isisu sethu siziva sigcwele kwaye sidumbile, akunjalo? Kuvakala ngathi ukutya akuyehli esiswini sethu. Okanye siziva singakhululekanga njengokubhodla rhoqo, isitshiso sentliziyo, kunye nokuhlanza. Esinye sezizathu zezi zinto sinokuba yindlela yakho yokugaya ukutya, oko kukuthi, amathumbu akho, acotha kancinci. Namhlanje, sithetha ngodidi olukhethekileyo lwamayeza oluza kunceda ngamaxesha anjalo.
Ngamafutshane, zithini ezi Prokinetic Agents?
Ii-Prokinetic agents luhlobo lwamayeza avuselela izihlunu kwindlela yakho yokugaya ukutya ukuba zinciphe, okanye "zityhale," kwaye zincede ukuhambisa ukutya ngokulula.
Khawuthelekelele, xa siginya ukutya, izihlunu ezisuka emqaleni ukuya esiswini nasemathunjini ziyafinyela zize ziphumle njengegagasi, zityhala ukutya phambili. Le nkqubo siyibiza ngokuba yi -peristalsis ezenzekelayo. Kufana nokucinezela nokucinezela into ngaphakathi kwityhubhu uze uyithumele phambili. Ngenxa yokuba le nkqubo yenzeka ngokufanelekileyo, umzimba wethu uyakwazi ukufunxa izondlo ozifunayo ekutyeni.
Nangona kunjalo, ukuba ngesizathu esithile le nkqubo yokuhamba ibuthathaka, ukutya kunokuhlala esiswini ixesha elide. Oku kunokubangela ukungakhululeki okufana nokudumba, ukuqhina, kunye nesitshiso. Kulapho amayeza abizwa ngokuba yiProkinetic Agents anceda khona ukunika amathumbu ethu "ukutyhala" nokubuyisela loo nkqubo.
Eli yeza lisebenza njani emzimbeni?
Ii-prokinetic agents zisebenza ngokuvuselela imithambo-luvo emathunjini ethu, nto leyo ebangela ukuba izihlunu zifinyele. Oku kwenza izinto ezimbalwa ezibalulekileyo:
- Yandisa ukushwabana komphimbo: Oku kubangela ukuba ukutya kungene ngokukhawuleza esiswini.
- Qinisa iLower Esophageal Sphincter (LES): Eli "sango" eliphakathi komqala nesisu sethu. Xa libuthathaka, i-asidi yesisu inokubuyela phezulu kwi-esophagus. Oku sikubiza ngokuba yi-heartburn, okanye i-GERD . Amayeza e-prokinetic aqinisa eli sango aze athintele i-asidi ukuba ingabuyeli phezulu.
- Iyandisa ukushwabana kwesisu: Oku kuvumela ukutya esiswini ukuba kuhambe ngokukhawuleza kungene emathunjini amancinci. Xa isisu siphuma ngokukhawuleza, amathuba okuba siphinde sinyuke mancinci.
- Inciphisa ixesha elithathwayo ukuze isisu siphume: Oku kunceda kakhulu ekulawuleni iimeko ezifana neGERD ekhankanyiweyo apha ngasentla.
Zeziphi iimeko ezisetyenziselwa ii-prokinetic agents?
Olu hlobo lwamayeza ludla ngokucetyiswa ngoogqirha kwiimeko apho ezinye iindlela zonyango zingakhange zinike ncedo, njengoko ezi zinokuba nemiphumo emibi.
| Imeko yezonyango | Kalula nje... | Linceda njani eli yeza? |
|---|---|---|
| I-Gastroparesis | Ukugaywa kokutya kuyalibaziseka kuba izihlunu zesisu azisebenzi kakuhle. Le meko ixhaphakile kubantu abanesifo seswekile. | Iyandisa ukushwabana kwesisu, isinceda sikhuphe isisu ngokukhawuleza. I-Metoclopramide liyeza eliphambili elivunyiweyo ngenxa yale njongo. |
| I-GERD (ukutshisa kwentliziyo/intlungu yesifuba) | Ingxaki yexesha elide ebangelwa yi-asidi yesisu ehlala ingena kwi-esophagus. | La mayeza awayonyango lwe-GERD ngokwawo. Nangona kunjalo, ukuba ukuphuma kancinci esiswini nako kuyimbangela ye-GERD, ugqirha wakho unokuwacebisa kunye namanye amayeza. |
| I-Dyspepsia esebenzayo | Iimpawu eziqhubekayo zokungagayi kakuhle ukutya emva kokutya, kodwa akukho sizathu sicacileyo sifumanekayo. | Inceda ekunciphiseni iimpawu ngokwandisa ukushwabana kwesisu, ikhuphe yonke into ngokukhawuleza. |
| Isicaphucaphu nokuhlanza | Ukuhlanza okungapheliyo kunye nesicaphucaphu ekunzima ukukulawula ngezinye iindlela zonyango. Ikwasetyenziselwa ukunyanga ukuhlanza okubangelwa yi-chemotherapy enikwa izigulana ezinomhlaza. | Ezi mpawu zilawulwa ngokuchaphazela amaziko okuhlanza engqondweni kunye nokukhawulezisa ukuphuma kwesisu. |
Ziziphi iintlobo eziphambili zee-prokinetic agents?
La mayeza anokwahlulwa abe ngamaqela amabini aphambili ngokusekwe kwindlela asebenza ngayo: Agonists kunye naAntagonists .
- Ama-Agonists: La ma-neurotransmitters asebenza njengee-neurotransmitters emzimbeni wethu kwaye enza into efanayo naleyo ayenzayo. Oko kukuthi, athumela umyalezo kwimisipha emathunjini ukuba inciphe.
- Ii-antagonists: Ezi zisebenza ngokuthintela ikhemikhali ethwala imiyalezo yemithambo-luvo ecothisa ukusebenza kwamathumbu ekufikeleleni kwimithambo-luvo. Oko kukuthi, zithintela umyalezo owenza amathumbu "acothe."
Kukho iindidi ezahlukeneyo zamayeza phantsi koku:
- Ii-Dopamine antagonists: I-Dopamine, ikhemikhali efumaneka engqondweni nasemathunjini, inciphisa ukusebenza kwamathumbu. La mayeza asebenza ngokuthintela ukusebenza kwe-dopamine. Imizekelo: I-Metoclopramide, i-Domperidone .
- Ii-agonists zeSerotonin: Zisebenza njengekhemikhali ebizwa ngokuba yi-serotonin kwaye zivuselela ukushwabana kwamathumbu. Imizekelo: I-Prucalopride .
- Ii-agonists zeMotilin: I-Motilin yikhemikhali elawula ukushwabana kwamathumbu ethu amancinci. Le yindlela ezisebenza ngayo ezi ziyobisi. Okumangalisayo kukuba, eli qela liquka ii-antibiotics ezifana ne -Erythromycin .
- Ii-agonists ze-cholinergic: Zisebenza njenge-neurotransmitter acetylcholine kwaye zibangele ukuba izihlunu zamathumbu zinciphe. Imizekelo: iBethanechol, iNeostigmine .
Kubaluleke kakhulu: Iziphumo ebezingalindelekanga zale mithi
Le yeyona nxalenye ibalulekileyo kweli nqaku. Ii-Prokinetic Agents aziloyeza elifana nePanadol lentloko eqhelekileyo. Zinokuba nemiphumo emibi kakhulu kwaye akufuneki zithathwe nangasiphi na isizathu ngaphandle kwengcebiso kagqirha.
Oogqirha banika la mayeza kuphela xa ezinye iindlela zonyango zingaphumelelanga, kwaye zihlala zinikwa ngeedosi eziphantsi kwaye zifutshane.
Iziphumo ebezingalindelekanga eziqhele ukubonwa:
- Isisu esibuhlungu
- Isicaphucaphu nokuhlanza
- Urhudo
- Umbono ofipheleyo
- Intloko ebuhlungu
- Ukudinwa kakhulu, ukozela
- Uxinzelelo kunye nokuxhalaba
Iziphumo ebezingalindelekanga ezinzulu ekufuneka uziqaphele:
Ezi mpawu zibaluleke kakhulu. Ukuba ufumana naziphi na kwezi mpawu ngelixa usela amayeza e-prokinetic, kufuneka wazise ugqirha wakho ngoko nangoko.
- I-Dystonia: Le yimeko apho izihlunu zomzimba zifinyela ngendlela engalawulekiyo, njengokutsalwa kwentamo ecaleni, amehlo eqengqeleka, okanye ulwimi luphuma ngaphandle.
- Iintshukumo zobuso ezingenziwanga ngabom (iTardive Dyskinesia): Le yimeko enokwenzeka emva kokuthatha amayeza ixesha elide. Iindawo zobuso, ezinje ngomlomo, ulwimi, nomhlathi, ziyashukuma ngokungazithandi. Le meko ngamanye amaxesha ayiphucuki nasemva kokuyeka amayeza.
- Iingxaki zentliziyo: Amanye amayeza, ingakumbi iDomperidone , anokubangela ukubetha kwentliziyo okungahambelaniyo (arrhythmias) kunye nokuhlaselwa yintliziyo. Ngenxa yesi sizathu, ukusetyenziswa kwala mayeza kuye kwathintelwa kwamanye amazwe.
Ngenxa yezi ngozi, ukuba ugqirha wakho unika eli yeza, thetha naye ngononophelo malunga nezinto ezilungileyo nezingalunganga. Qiniseka ukuba uxelela ugqirha wakho ngazo naziphi na ezinye iimeko zempilo onazo kunye nezinye iziyobisi ozisebenzisayo.
Umyalezo Wokuya Ekhaya
- Ii-prokinetic agents luhlobo lwamayeza anika "ukutyhala" inkqubo yokugaya ukutya "ecothayo", okwenza ukutya kuhambe lula.
- Ezi zisetyenziselwa ukunyanga iimeko ezifana ne-gastroparesis (ukungasebenzi kakuhle kwesisu) kunye ne-GERD enzima.
- Ezi azisetyenziswa rhoqo njengonyango lokuqala ngenxa yomngcipheko weziphumo ebezingalindelekanga ezinzulu.
- Ungaze usebenzise la mayeza ngaphandle kwengcebiso kagqirha.
- Ukuba ufumana naziphi na iimpawu ezingaqhelekanga ngelixa usebenzisa eli yeza, ingakumbi ukuxhuzula kwemisipha ebusweni okanye emzimbeni, xelela ugqirha wakho ngoko nangoko.
- Ukuba ugqirha wakho ukunike eli yeza, kungenxa yokuba ugqibe kwelokuba iingenelo zinkulu kuneengozi ezinokubakho. Ngoko ke, landela imiyalelo kagqirha wakho ngokuchanekileyo.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho