Ngaba uhlala unesifo se-gastritis? Okanye unesicaphucaphu esifubeni sakho okanye uziva unomsindo emqaleni wakho? Ngamaxesha anje, uninzi lwethu luqhele ukuthatha amayeza kwivenkile yezonyango. Amaxesha amaninzi, uhlobo lwamayeza athathwa ngolu hlobo yiProton Pump Inhibitors, okanye njengoko silubiza, "unyango lwe-gastritis". Kodwa, ngaba siyazi kakuhle ukuba ngawaphi la mayeza, indlela asebenza ngayo, kwaye kufuneka athathwe ixesha elingakanani? Namhlanje, siza kuthetha ngale nto.
Zithini ezi proton pump inhibitors (PPIs)?
Ngamafutshane, olu luhlobo lwamayeza anciphisa i-asidi, okanye i-asidi, esiswini sakho. Ngoku usenokuba ucinga, "Akulunganga na ukuba ne-asidi yesisu?" I-asidi yesisu yinto esingenakuphila ngaphandle kwayo. Isinceda sigaye ukutya esikutyayo kwaye ibulala neentsholongwane eziyingozi ezingena nokutya.
Kodwa ingxaki iqala xa le asidi iba ninzi kakhulu, okanye xa isiya apho ingafanele ukuba khona, njengomphunga wakho. Kulapho ke iingxaki ezifana nentliziyo ebuhlungu kunye nezilonda zesisu ziqala khona. Kulapho ke la mayeza abizwa ngokuba yi-PPIs asinceda khona.
Zeziphi iimeko eziphambili ezinyangwa nge-PPI?
Ii-PPI zisetyenziselwa ukunyanga izifo ezininzi ezinxulumene ne-asidi yesisu. Makhe sijonge ezona ziphambili.
| Imeko yezonyango | Kalula nje, okwenzekayo kukuba |
|---|---|
| I-GERD / I-Chronic Acid Reflux | Oku kubizwa ngokuba yi-heartburn. I-asidi yesisu enyuka iye kwi-esophagus inokubangela umonakalo kwi-esophagus (i-erosive esophagitis) . Ii-PPI zinciphisa i-asidi yesisu kwaye zivumela umonakalo ukuba uphole. |
| Izilonda zePeptic (Izilonda zesisu kunye neZilonda zamathumbu amancinci) | I-asidi yesisu inokonakalisa ulwelo olukhuselayo lwesisu okanye amathumbu amancinci, nto leyo ebangela izilonda. Ezi zilonda zinokukhula ngokuqhubeka nokusebenzisa amayeza athile okudambisa iintlungu (ii-NSAID) . Ii-PPI zinokunceda ukuphilisa ezi zilonda. |
| Usulelo lwe-H. pylori | Le yintsholongwane ebangela izilonda esiswini. Ii-PPI zinikwa kunye nee-antibiotics ukubulala le ntsholongwane. Oku kunciphisa i-asidi esiswini, okuvumela ukuba ii-antibiotics zisebenze ngcono. |
| Isifo sikaZollinger-Ellison | Le yimeko engaqhelekanga. Ezinye iithumba emzimbeni zivelisa ihomoni ebangela ukuba isisu sivelise iasidi eninzi kakhulu. Ii-PPI zinokuyilawula le meko. |
Lisebenza njani eli yeza?
Kulula kakhulu ukuyiqonda le nto. Khawuthelekelele ukuba kukho 'iipompo' ezincinci ngaphakathi esiswini sakho ezenza i-asidi. Ngokwesayensi, ezi zibizwa ngokuba ziipompo ze-hydrogen-potassium ATPase. Ngamafutshane, "ziipompo zeproton."
Ngoku, into eyenziwa leli yeza le-PPI 'kukuthintela' umsebenzi wezo pumps zivelisa i-asidi, oko kukuthi, ziyazimisa. Kufana nokucima iswitshi kwi-water motor.
Kodwa oku akumisi yonke imveliso ye-asidi esiswini. Ukuba uthatha i-PPI malunga neentsuku ezi-5 zilandelelana, imveliso ye-asidi esiswini iya kuncipha malunga nama-65%. Ama-35% aseleyo anele ukugaya ukutya. Ngoko ke akukho nto inokubangela ixhala.
Ziziphi iintlobo zePPI eziqhelekileyo?
Kukho iintlobo ezahlukeneyo ze-PPI. Ezinye zingathengwa ngaphandle kwekhawuntara (OTC) kwikhemesti ngaphandle kwemvume kagqirha, ngelixa ezinye zifuna imvume kagqirha.
| Igama eliqhelekileyo | Amagama eeMveliso aqhelekileyo |
|---|---|
| Iintlobo ezifumanekayo ngencwadi kagqirha okanye ngaphandle kwayo | |
| I-Esomeprazole | I-Nexium® |
| I-Lansoprazole | I-Prevacid® |
| I-Omeprazole | IPrilosec® |
| Iintlobo zifumaneka kuphela ngomyalelo kagqirha | |
| I-Dexlansoprazole | I-Dexilant® |
| I-Pantoprazole | I-Protonix® |
| I-Rabeprazole | I-AcipHex® |
Zifanele zisetyenziswe njani ezi zinto?
Eli yeza liza likwimo yekhaphu okanye yepilisi. Kwabo banengxaki yokuginya iipilisi, ezinye iikhaphu zingaxutywa nento efana ne-applesauce ukuze kuthathwe umgubo.
Eyona nto ibalulekileyo kukuba uthatha nini amayeza. Uninzi lwee-PPI zisebenza kakuhle xa zithathwa ungenanto esiswini . Kucetyiswa ukuba uzithathe imizuzu engama-30 ukuya kwiyure ngaphambi kwesidlo sakusasa. Isizathu kukuba oku kunika amayeza ixesha lokuba afunxwe aze aqale ukusebenza, ngaphambi kokuba i-asidi yesisu iqokeleleke emva kokutya.
Ndingayithenga malini?
Oku ngokuqinisekileyo yinto eza kugqitywa ngugqirha wakho. Abanye abantu banokufuna ipilisi enye kusasa. Abanye banokuxelelwa ukuba bathathe enye kusasa nenye ebusuku. Kuxhomekeke kwimeko yakho yempilo. Ngoko ke, kubaluleke kakhulu ukulandela imiyalelo kagqirha wakho.
Kuthatha ixesha elingakanani ukuba ii-PPI zisebenze?
Eli asiloyeza lokunceda ngokukhawuleza. Kungathatha usuku olu-1 ukuya kutsho kwiintsuku ezi-4 ukuze uve iziphumo ezipheleleyo zeyeza.
Khawuthelekelele utye ukutya okuneziqholo waza ngequbuliso waziva utshile esifubeni sakho. Ngamaxesha anjalo, i-antacid (umz., iDigene) okanye i-histamine (H2) blocker (umz., iFamotidine) inokunika isiqabu ngokukhawuleza kunePPI. Nangona kunjalo, iziphumo zazo ziyaphela ngokukhawuleza.
Ii-PPI lunyango olunika iziphumo ezihlala ixesha elide, olufanele abantu abaneengxaki ze-asidi engapheliyo.
Ngaba kukho naziphi na iziphumo ebezingalindelekanga kwezi zinto?
Uninzi lwabantu alufumani ziphumo zimbi, kodwa njengalo naliphi na iyeza, abanye abantu banokufumana iziphumo ezingezizo ezibi.
- Isisu esibuhlungu
- Ukuqhinwa
- Urhudo
- Isiyezi
- Umlomo owomileyo
- Intloko ebuhlungu
- Ifiva
- Ukuzalisa isisu
- Ukurhawuzelela nokuhlaba
Iingozi zokusetyenziswa ixesha elide
Nangona ii-PPI ngokubanzi zithathwa njengeyeza elikhuselekileyo, abaphandi bafumanise iingozi ezithile ezinxulumene nokusetyenziswa kwazo ixesha elide ngaphandle kwengcebiso kagqirha .
- Usulelo lweClostridium difficile (C. diff): Ulungelelwano phakathi kweebhaktheriya ezilungileyo nezingalunganga emathunjini luyatshintsha, nto leyo ebangela urhudo oluyingozi.
- Ukwaphuka: Kungenza kube nzima emzimbeni ukufunxa ikhalsiyam, nto leyo enokunyusa umngcipheko wokuqhekeka kwesinqe, esihlahleni, okanye emgogodleni.
- Isifo sezintso: Ukusetyenziswa ixesha elide kunokunyusa umngcipheko wokuba nesifo sezintso esingapheliyo (CKD).
- Ukunqongophala kwesondlo: Umzimba unokunciphisa ukufunxwa kwawo yi-magnesium kunye ne-vitamin B12. Ezi zizondlo ezibalulekileyo kwinkqubo yethu yemithambo-luvo kunye nemisipha.
Ezi ngozi zisafundwa, ngoko ke oogqirha badla ngokuzama ukulawula iimpawu zakho ngokukunika idosi ephantsi kangangoko ngexesha elifutshane kangangoko .
Ndifanele ndimbone nini ugqirha?
Ukuba ugqirha uninike ii-PPI, kufuneka uthethe nogqirha wakho malunga nokuyeka amayeza okanye ukutshintsha umthamo.
Ukuba usebenzisa ii-PPI ezithengiswa ngaphandle kwekhawuntara (ii-OTC) kwaye ufumanisa ukuba uyazidinga yonke imihla ukulawula iimpawu zakho, ngokuqinisekileyo kuya kufuneka ubone ugqirha ukuze ufumane ukuxilongwa kunye nonyango olufanelekileyo.
Ukuba ufumana ezi mpawu zilandelayo, bona ugqirha wakho ngoko nangoko:
| Uphawu | Inkcazo |
|---|---|
| Impendulo yokunganyamezelani | Ukurhawuzelelwa lusu, ukurhawuzelelwa kakhulu, ukudumba. |
| Iimpawu zomonakalo wezintso | Ukuncipha kokuphuma komchamo, ukudumba kwezandla, amaqatha, okanye iinyawo. |
| Iimpawu zokungabikho kwe-magnesium | Ukudinwa kakhulu, ukubetha kwentliziyo okungahambelaniyo, iintlungu zemisipha. |
| Iimpawu zokunqongophala kwe-vitamin B12 | Intlungu, ukuba ndindisholo, isiyezi , ukudideka ezingalweni okanye emilenzeni. |
| Urhudo oluqatha okanye umkhuhlane | Urhudo olungapheliyo okanye umkhuhlane. |
Umyalezo Wokuya Ekhaya
- Ii-PPI ziyindlela yonyango lweengxaki ze-asidi ezihlala ixesha elide, kungekhona ukuphelisa ngokukhawuleza.
- Soloko usela amayeza akho ngexesha elimiselweyo (ngesiqhelo ngaphambi kokutya), njengoko kuyalelwe ngugqirha wakho.
- Kuphephe ukusebenzisa ii-PPI rhoqo ixesha elide ngaphandle kwengcebiso kagqirha.
- Ukuba uyalidinga eli yeza imihla ngemihla okanye ukuba kukho naziphi na iziphumo ebezingalindelekanga, qiniseka ukuba ubona ugqirha wakho.
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