Ngaba ugqirha wakho wakha wakucela ukuba wenze i-scan ekhethekileyo, njenge-PET scan? Okanye wathetha ngenaliti ekhethekileyo njengonyango lomhlaza? Emva koko mhlawumbi uzive usoyika kancinci xa usiva igama elithi "radioactive." Kodwa ungoyiki. Namhlanje sithetha ngolu hlobo lumangalisayo lwamayeza oluphucuke kakhulu kwisayensi yezonyango, olusetyenziselwa ukuxilonga nokunyanga izifo.
Zithini ezi ziyobisi ze-radiopharmaceuticals?
Ngamafutshane, la ngamayeza akhethekileyo enzelwe ukusetyenziswa kwezonyango, anemitha encinci kakhulu kwaye elawulwayo. Ngokwenyani, la luhlobo lweyeza. Kodwa ngaphakathi kweli yeza kukho into efana "ne-tracker" encinci. Singajonga amandla akhutshwa yilo ngeekhamera ezikhethekileyo.
Ezi zenziwa, zisasazwa, kwaye zisetyenziswa ngabantu abafumene uqeqesho olukhethekileyo kweli candelo. Umzekelo, iingcali ze-nyukliya, iingcali ze-radiology, kunye neengcali ze-radiation oncologists zizisebenzisa ngononophelo olukhulu.
Zisetyenziselwa ntoni ezi ziyobisi?
Kukho iindlela ezimbini eziphambili zokusebenzisa ezi Radiopharmaceuticals. Enye kukufumanisa izifo (Diagnostic) , enye kukunyangela izifo (Therapeutic) . Khawuthelekelele ukuba sisebenzisa ubuchwepheshe obufanayo, singabona ingxaki engaphakathi emzimbeni size sinyange loo ngxaki. Masijonge ezi zimbini ngokwahlukeneyo.
1. Indlela yokunceda ekuxilongeni izifo (Diagnostic Radiopharmaceuticals)
Le yeyona ndlela ixhaphakileyo esetyenziswa ngayo la mayeza. Okwenzekayo apha kukuba usela, uphefumle, okanye ufake isixa esincinci nesikhuselekileyo sale nkunkuma inemisebe emzimbeni wakho. Sikwabiza ezi ziyobisi ngokuba zii-radiotracers .
Cinga ngomzimba wakho njengesixeko esikhulu. Eli yeza lifana ne-GPS tracker. Liya ngqo kwindawo yengxaki. Emva koko lithumela umyalezo omncinci ukusuka apho.
Xa sele ingaphakathi emzimbeni, eli yeza liya kwindawo apho kukho isifo, usulelo, okanye ingxaki. Emva koko, ikhamera ekhethekileyo, efana nekhamera ye-gamma, isetyenziselwa ukuthatha imifanekiso yeendawo apho iyeza liqokelele khona. Kule mifanekiso, ugqirha unokubona ngqo indlela amalungu akho asebenza ngayo, indlela igazi lakho elihamba ngayo, okanye ukuba kukho iiseli zomhlaza.
- Imizekelo:
- Iiskeni zePET (iiskeni zePositron Emission Tomography): Iyeza elibizwa ngokuba yi-`Fluorine-18` lisetyenziswa kakhulu koku.
- Uvavanyo lwamathambo, isibindi, kunye nezintso: Iyeza elithi `Technetium 99m` lelona lisetyenziswa kakhulu ehlabathini ngenxa yale njongo.
- Uvavanyo lokusebenza kwemiphunga:Baphefumla iyeza elibizwa ngokuba yi-`Xenon-133`.
- Uvavanyo lwemisipha yentliziyo: Iyeza elibizwa ngokuba yi-`Rubidium-82` lifakwa emthanjeni.
2. Ii-Radiopharmaceuticals zonyango
Le ndlela yindlela entsha, kodwa esebenza kakhulu yonyango, ingakumbi kumhlaza. Ibandakanya ukufaka iyeza elinamandla kancinci elinomhlaza emzimbeni kunalelo linikwayo ukuze kufunyanwe isifo.
Oku kufana nerokhethi eya ngqo kwindawo ekujoliswe kuyo. Eli yeza likhangela ngqo iiseli zomhlaza, lizinamathele kuzo, lize lizitshabalalise. Eyona nzuzo inkulu yoku kukuba akukho monakalo mkhulu kwezinye iiseli eziphilileyo emzimbeni. Kuba olu nyango lujolise ngqo kwiiseli zomhlaza kuphela. Oku kwahlukile kwindlela yonyango esebenzisa imitha evela ngaphandle (`External Beam Radiation Therapy`).
Umahluko phakathi kwezinto ezimbini eziphambili ezisetyenziswayo
Ukuze sikuqonde lula oku, makhe sijonge umahluko phakathi kwezi ndlela zimbini zokusetyenziswa.
| Ukusetyenziswa | Inkqubo eyenzekayo | Injongo ephambili |
|---|---|---|
| Uxilongo | Kunikwa amayeza amancinci kakhulu, akhuselekileyo, kwaye imiqondiso ekhutshwayo ithathwa ngekhamera ekhethekileyo, nto leyo ekhokelela kwimifanekiso yangaphakathi lomzimba. | Ukubona indlela amalungu omzimba asebenza ngayo kunye nokuchonga iindawo ezinesifo. |
| Unyango | Ngokunika idosi enamandla yeyeza, lithunyelwa ngqo kwiiseli ezinobungozi, ezifana neeseli zomhlaza, kwaye litshatyalaliswe. | Ukutshabalalisa iiseli ezinesifo, ezifana neeseli zomhlaza, kunye nokunyanga esi sifo. |
Zithini ii-radiopharmaceuticals ezisetyenziswa kunyango lomhlaza?
Kukho amayeza e-radiopharmaceuticals asebenzayo kakhulu okwangoku avunyiweyo ukunyanga umhlaza.
- I-PLUVICTO® (`lutetium Lu 177 vipivotide tetraxetan`):Isetyenziselwa ukunyanga ezinye iimeko zomhlaza weprostate osasazeke kwezinye iindawo (i-metastatic).
- I-Lutathera™ (`Lutetium Lu 177 dotatate`): Le isetyenziselwa ukunyanga ii-neuroendocrine tumors ezithile ezenzeka esiswini, kwi-pancreas, nasemathunjini.
- Iodine-131: Isetyenziselwa ukunyanga umhlaza we-thyroid kunye neemeko ezibangela ukuveliswa kakhulu kweehomoni ze-thyroid, ezifana nesifo sikaGraves.
- I-Radium-223: Xa umhlaza weprostate usasazeke (wasasazeka) waya emathanjeni, oku kusebenza kakhulu ekutshabalaliseni iiseli zomhlaza kuloo mathambo.
Ukongeza, uvavanyo lweklinikhi luyaqhubeka okwangoku malunga nokusetyenziswa kwala mayeza kwezinye iintlobo ezininzi zomhlaza, oko kuthetha ukuba oku kuya kuba yinxalenye ebaluleke kakhulu yonyango lomhlaza kwixesha elizayo.
Ngaba la mayeza akhuselekile ngokwenene? Ngaba simele soyike?
Lo ngumbuzo omkhulu wonke umntu anawo. Kuqhelekile ukuba soyike xa sisiva igama elithi "radioactive." Kodwa le yinyaniso.
Ewe, la mayeza akhuselekile kakhulu xa ephathwa ngokuchanekileyo ziingcali.
Khawucinge nje, isixa samayeza anikwayo ukuze kufunyaniswe izifo sincinci kakhulu kangangokuba asizukulimaza umzimba wakho. Siza kususwa ngokupheleleyo emzimbeni wakho kwiiyure okanye iintsuku ezimbalwa.
Umlinganiselo wamayeza anikwa unyango unamandla kancinci kunoko. Ke ngoko, ezinye iziphumo ebezingalindelekanga zinokubakho. Kodwa njengakweyiphi na imithi, nalapha, oogqirha bajonga ukuba izibonelelo zamayeza zingaphezulu na kuneziphumo ebezingalindelekanga. Xa kuthelekiswa nethuba lokunyanga isifo esibi njengomhlaza, ezo ziphumo bezingalindelekanga zinokulawulwa.
Ukuba unikwe unyango okanye uvavanyo olufana nolu, ugqirha wakho uya kukuchazela yonke into ngalo, iingenelo zalo, kunye nemiphumo enokubakho. Buza ngayo nayiphi na imibuzo okanye iinkxalabo onokuba nazo ngelo xesha.
Umyalezo Wokuya Ekhaya
- Ii-Radiopharmaceuticals luhlobo olukhethekileyo lwamayeza ane-radioactivity elawulwayo esetyenziselwa ukuxilonga nokunyanga izifo.
- Iingcali zokuxilonga zisebenzisa iidosi ezincinci kakhulu nezikhuselekileyo zemitha ukunceda ukubona indlela amalungu omzimba asebenza ngayo.
- Iindlela zonyango zisetyenziselwa ukujolisa nokutshabalalisa iiseli ezinobungozi, ezifana neeseli zomhlaza.
- Ezi ziphathwa ngononophelo olukhulu ziingcali, ngoko ke zikhuselekile kakhulu xa zisetyenziswa ngokuchanekileyo.
- Ukuba unemibuzo okanye iinkxalabo malunga nolu hlobo lovavanyo okanye unyango, thetha nogqirha wakho ngalo mba ngokukhululekileyo.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho