Xa wena okanye umntu osondeleyo kuwe enyangwa umhlaza, kuyinto eqhelekileyo ukuba nomdla kancinci kwaye uxhalabele amayeza anikwa ngugqirha wakho. Namhlanje, sithetha ngeyeza elithile elisetyenziselwa ukunyanga umhlaza onjalo, iTrametinib. Kweli nqaku, siza kuthetha ngeli yeza ngolwimi olulula noluqondakala lula.
Yintoni iTrametinib?
Ngamafutshane, i-tramatinib liyeza elisetyenziselwa ukulawula ukukhula kweeseli zomhlaza, oko kukuthi, ukumisa ukukhula kwazo. Lisebenza njengonyango olujoliswe kulo. Oku kuthetha ukuba eli yeza lijolise kwaye lonakalise ngokukodwa iiseli zomhlaza endaweni yeeseli eziphilileyo.
Eli yeza lisetyenziswa kakhulu kwezi zinto zilandelayo:
- I-Melanoma luhlobo lomhlaza wolusu.
- Uhlobo lomhlaza wemiphunga olubizwa ngokuba yi -non-small cell lung cancer .
- Ngomhlaza we-thyroid.
- Kweminye imithambo eqinileyo eneempawu ezithile zofuzo.
Umsebenzi ophambili wale chiza kukunciphisa isantya apho iiseli zomhlaza zahlukana kwaye zisasazeka khona. Oku luncedo olukhulu ekulawuleni umhlaza.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba uqale i-tramatinib, kubaluleke kakhulu ukunika ugqirha wakho umfanekiso opheleleyo wempilo yakho. Kuba ezinye iimeko zonyango zifuna unonophelo olukhethekileyo xa usebenzisa eli yeza. Qiniseka ukuba uxelele ugqirha wakho ukuba unayo nayiphi na kwezi zilandelayo:
| Isifo okanye imeko | Inkcazo |
|---|---|
| Iingxaki zokopha | Ukuthambekela kokopha okanye izifo ezinxulumene negazi. |
| Amahlwili egazi | Ukuba ukhe waba namahlwili egazi ngaphambili. |
| Isifo seswekile | Amanqanaba aphezulu eswekile egazini. |
| Isifo sentliziyo | Naluphi na uhlobo lwesifo sentliziyo. |
| Igazi elonyukayo | Ukuba une-high blood pressure. |
| Isifo sezintso okanye sesibindi | Iingxaki zokusebenza kwezintso okanye kwesibindi. |
| Izifo zemiphunga | Ezinye izifo ezinxulumene nemiphunga ezifana ne-asthma. |
| Iingxaki zenkqubo yokugaya ukutya | Iimeko ezinje nge-colitis. |
| Iingxaki zokubona | Nasiphi na isifo esinxulumene namehlo. |
| Ukukhulelwa okanye ukuncancisa | Ukuba uzama ukukhulelwa, ukhulelwe, okanye uncancisa. |
| Ii-aleji | Ukuba une-allergies kwi-tramatinib okanye nakweyiphi na eminye imithi, ukutya, okanye idayi. |
Ndingayisebenzisa njani kanye kanye le yeza?
Indlela yokusebenzisa eli yeza ilula kakhulu, kodwa ibaluleke kakhulu.
- Ipilisi yomlomo: Le yipilisi ethathwa ngamanzi.
- Yisele ungenanto esiswini: Ukuze ufumane iziphumo ezilungileyo, thatha eli yeza ubuncinane iyure enye ngaphambi okanye iiyure ezimbini emva kokutya .
- Ngexesha elifanayo yonke imihla: Zama ukusela amayeza akho ngexesha elifanayo yonke imihla kangangoko unako. Oku kuya kunceda ukugcina amanqanaba amayeza emzimbeni wakho ehambelana.
- Landela imiyalelo kagqirha wakho: Qhubeka usela eli yeza de ugqirha wakho akuxelele ukuba uyeke. Musa ukuyeka phakathi.
Ngaba eli yeza lifanele linikwe abantwana?
Kwezinye iimeko ezikhethekileyo, eli yeza linokunikwa abantwana abangaphezu kweminyaka emi-6 ubudala. Kodwa kufuneka lenziwe ngononophelo olukhulu kwaye phantsi kweliso elikhethekileyo lezonyango. Qiniseka ukuba uthetha nogqirha wakho ngale nto.
Ungenza ntoni ukuba uthatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, fowunela iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Kuthekani ukuba ndiphoswa lidosi leyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-12 ngaphambi kokuba uthathe idosi elandelayo (oko kukuthi, ukuba ufike emva kwexesha ngaphezulu kweeyure ezili-12), yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha eliqhelekileyo. Ungaze uthathe iidosi ezimbini ngaxeshanye ukuze ubuyisele idosi oyiphosileyo.
Izinto ekufuneka sizilumkele ngakumbi xa sithatha amayeza
Ngelixa usela eli yeza, kubaluleke kakhulu ukuqaphela utshintsho olusemzimbeni wakho.
- Ukuhlolwa rhoqo kwezonyango: Qiniseka ukuba uya kumadinga kagqirha wakho. Oku kubalulekile ukuze ujonge inkqubela yakho.
- Umngcipheko wokopha: Eli yeza linokuyonyusa kancinci ingozi yokopha okanye ukukrwela. Ukuba ubona nayiphi na imikrwelo okanye ukopha okungaqhelekanga, xelela ugqirha wakho ngoko nangoko.
- Umbono: Amehlo akho aza kuhlolwa ngaphambi kokuba uqale ukuthatha amayeza kwaye ngelixa uwasebenzisa. Ukuba ubona izinto ezingabonakali kakuhle, ubona izinto ezijikeleze ukukhanya, okanye ubona izinto ezingabonakaliyo, xelela ugqirha wakho ngoko nangoko.
- Amanqanaba eswekile egazini: Eli yeza linokunyusa amanqanaba eswekile egazini. Lo mngcipheko uphezulu nangakumbi ukuba unesifo seswekile. Buza iqela lakho lezempilo ngeendlela zokunciphisa lo mngcipheko.
Ulwazi olukhethekileyo malunga nokukhulelwa nokuncancisa
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Le ngongoma ibaluleke kakhulu.
* Abafazi: Musa ukukhulelwa ngelixa usela eli yeza kwaye kangangeenyanga ezi-4 emva kokuyeka iyeza. Xelela ugqirha wakho ngoko nangoko ukuba uceba ukukhulelwa okanye ukrokrela ukuba ukhulelwe.
* Amadoda: Ukuba usela eli yeza, musa ukuzama ukukhulelwa umntwana ngelixa usela eli yeza kwaye emva kweenyanga ezi-4 uyekile.
* Ukuncancisa: Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye kangangeenyanga ezi-4 emva kokuba uyekile.
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Eli yeza linokubangela ingozi enkulu kusana olungekazalwa. Linokuchaphazela nokuzala. Ukuba uneenkxalabo malunga noku, thetha nogqirha wakho.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengalo naliphi na iyeza, i-tramatinib inokubangela iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Eyona nto ibalulekileyo kukwazi ezi zinto kwaye uthathe amanyathelo ukuba ubona naziphi na iimpawu ezinzulu.
| Uhlobo lwesiphumo esibi | Iimpawu |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi okanye umqala. |
| Ukopha okungaqhelekanga | Indle emnyama okanye enegazi, ukuhlanza okufana nekofu egayiweyo, umchamo obomvu/omdaka omnyama, amabala amancinci abomvu/omfusa eluswini, kunye nokudumba okungaqhelekanga. |
| Ihlwili legazi | Intlungu yomlenze, ukudumba okanye ukufudumala, ubunzima bokuphefumla, intlungu yesifuba. |
| Utshintsho lombono | Umbono ofipheleyo, ukubona ii-halos ezijikeleze izibane, ukulahlekelwa ngumbono. |
| Ukumelwa yintliziyo | Ubunzima bokuphefumla, ukudumba kwamaqatha, iinyawo, izandla, ukunyuka kobunzima ngequbuliso, ukudinwa okungaqhelekanga. |
| Iswekile ephezulu egazini (iHyperglycemia) | Ukoma kakhulu, ukuchama rhoqo, ukudinwa okungaqhelekanga, ukubona izinto ezingaqhelekanga. |
| Umkhuhlane, ukurhawuzelela kolusu | Ezi zisenokuba ziimpawu zesifo esinzulu. |
| Izinto omele uzixelele ugqirha wakho ukuba azisoloko zimbi, kodwa ziqhubeka | |
| Isicaphucaphu nokuhlanza | Ukungakhululeki esiswini, ukuhlanza. |
| Ukudumba | Ukudumba kwamaqatha, izandla, okanye iinyawo. |
Ungayigcina njani imithi ikhuselekile?
- Gcina kude nabantwana kunye nezilwanyana zasekhaya.
- Gcina efrijini: Eli yeza kufuneka ligcinwe phakathi kwe-2 kunye ne-8 degrees Celsius (2°C - 8°C), oko kuthetha ukuba libekwe kwishelufu engaphakathi yefriji, hayi emnyango .
- Khusela ekukhanyeni nasekufumeni. Gcina ibhotile yamayeza ivaliwe kakuhle.
- Iphakheji engaphakathi kwebhotile: Musa ukuyisusa iphakheji encinci (i-desiccant) engaphakathi kwebhotile yeyeza ukuze kufunxwe umswakama. Inceda ukugcina iyeza litsha.
- Amayeza aphelelwe lixesha: Musa ukusebenzisa amayeza aphelelwe lixesha. Nxibelelana nogqirha wakho malunga nendlela yokuwalahla ngokufanelekileyo.
Umyalezo Wokuya Ekhaya
- I-Trametinib lunyango olujoliswe kulo olulawula ukukhula kweeseli zomhlaza.
- Soloko usela eli yeza ungenanto esiswini, kanye njengoko ugqirha wakho ekuxelele, nangexesha elimiselweyo.
- Ngaphambi kokuba uqalise amayeza, xelela ugqirha wakho ngazo zonke iimeko zakho zempilo kunye nee-aleji.
- Kuphephe ukukhulelwa nokuncancisa ngokupheleleyo xa usebenzisa amayeza kwaye emva kweenyanga ezi-4 uyekile. Eli cebiso lisebenza kubafazi nakumadoda.
- Ukuba ubona naziphi na iziphumo ebezingalindelekanga ezinje ngokopha okungaqhelekanga, utshintsho embonweni, ubunzima bokuphefumla, okanye ukurhawuzelelwa kakhulu lusu, yazisa ugqirha wakho ngoko nangoko.
- Ukuba unemibuzo malunga nale mithi, ungoyiki ukuyixoxa nogqirha wakho.
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