Ngaba wakha waphawula ukuba xa unomkhuhlane, umchamo wakho ujika ube nombala weti? Okanye ngaba uqaphela ukuba umchamo wakho unegwebu elininzi? Nangona abantu abaninzi becinga ukuba ezi zizinto eziqhelekileyo, oku kungaba luphawu lokuqala lokuba kukho into engalunganga ngezintso zakho. Namhlanje siza kuthetha ngemeko ebizwa ngokuba yi-IgA Nephropathy, echaphazela imizimba yethu buthule kwaye yinto abantu abaninzi abangazange bayive.
Ngamafutshane, yintoni i-IgA Nephropathy?
Esi sisifo esonakalisa izintso ngenxa yengxaki kwinkqubo yethu yokuzikhusela komzimba. Ngokuchanekileyo, esi sisifo sokuzikhusela komzimba .
Cinga ngenkqubo yethu yomzimba yokuzikhusela njengomkhosi okhusela ilizwe. Lo mkhosi unohlobo olukhethekileyo lwamajoni, esiwabiza ngokuba zii-antibodies . Umsebenzi wawo kukufumana nokutshabalalisa iintshaba, ezifana neentsholongwane kunye neebhaktheriya, ezingena emzimbeni. I-Immunoglobulin A, okanye i-IgA, yenye yezo antibody ezikhethekileyo.
Umntu one-IgA Nephropathy unotshintsho oluncinci, okanye ukusilela, kwezinye zee-antibodies ze-IgA eziveliswa emzimbeni. Ngenxa yesi sizathu, abanye abakhuseli kwinkqubo yethu yokuzikhusela abakwazi ukuyibona le IgA ingaqhelekanga. Bacinga ukuba lutshaba oluvela ngaphandle. Ngoko ke, bahlasela le IgA ingaqhelekanga baze bahlangane ukuze benze ii-clumps ezinkulu.
Ezi zixhobo zokukhusela iintsholongwane zihamba egazini zize zinamathele kwinkqubo yokucoca ethambileyo yezintso zethu, ebizwa ngokuba yi-glomeruli . Oku kubangela ukudumba apho, kwaye ngokuhamba kwexesha, izintso ziqala ukonakala.
Lo monakalo uthintela izintso ekuhluzeni igazi ngokufanelekileyo. Oku kubangela ukuba umzimba ulahlekelwe yimilinganiselo yawo yamachiza. Ukuba awunyangwa, lo monakalo ungaqhubekela phambili kwisifo sezintso esikwinqanaba lokugqibela.
Ngaba kukho unobangela othile wesi sifo?
Izazinzulu azikafumani unobangela ochanekileyo wesi sifo. Kodwa asisuleli. Kukholelwa ukuba sinxulumene nemfuza. Oko kuthetha ukuba ukuba umntu kusapho lwakho unaso, unethuba elincinci lokuba naso.
Kwakhona, ezinye iimeko zempilo zinokuba 'yimbangela' yokuqala oku.
| Izinto ezibangela | Inkcazo |
|---|---|
| Izifo zesibindi | I-Cirrhosis, kunye nosulelo olungapheliyo lwe-hepatitis B kunye ne-C. |
| Isifo seCeliac | Isifo sokugaya ukutya apho iprotein igluten efumaneka kwiinkozo ingenakugaywa. |
| Ezinye izifo | I-HIV kunye nezinye izifo ezibangelwa ziibhaktheriya nazo zinokuba negalelo. |
Nangona esi sifo sinokuvela nakweyiphi na iminyaka, iimpawu zihlala zibonakala kubantu abangaphantsi kweminyaka engama-40. Amadoda nawo anamathuba aphindwe kabini okuba naso kunabasetyhini.
Masifumanise ukuba zeziphi kanye kanye iimpawu.
Eyona ngxaki inkulu ngesi sifo kukuba asibonisi zimpawu kwasekuqaleni. Yiyo loo nto abantu abaninzi bengazi nokuba banaso esi sifo.
Nangona kunjalo, uphawu oluphambili nolucacileyo abanye abantu abalubonayo ligazi kumchamo (hematuria) xa benento efana nomkhuhlane, umkhuhlane, okanye usulelo lomphimbo . Umchamo ungabonakala ngathi unombala weti, umbala we-cola, okanye ubomvu. Nje ukuba usulelo luphele, umchamo ubuyela kumbala wawo wesiqhelo.
Olunye uphawu oluphambili ngumchamo onamagwebu . Oku kungenxa yokukhutshwa kweproteni kumchamo (proteinuria).
Ukongeza kwezi, kunokubakho nezinye iimpawu ezininzi:
- Ukudumba emilenzeni, ingakumbi emaqatheni.
- Uxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi oluphezulu).
- Ukuba esi sifo siqhubeka ixesha elide, iimpawu zokungasebenzi kakuhle kwezintso zingabonakala.
Uyifumana njani le nto, Gqirha?
Ukuba unale mpawu, ugqirha wakho uza kuqala enze uvavanyo lomchamo ukujonga igazi okanye iproteni kumchamo. Nangona kunjalo, ekubeni ezi zinokubonakala kwezinye izifo ezininzi zezintso, azinakuqinisekisa i-IgA Nephropathy.
Eyona ndlela ikuphela kwayo yokuqinisekisa i-100% ye-IgA Nephropathy kukwenza i-biopsy yezintso .
Musa ukoyika xa usiva oku. Olu luvavanyo oluqhelekileyo olwenziwa esibhedlele. Ugqirha uza kukwenza ungabi nazinzwane umqolo, afake inaliti encinci kakhulu kwizintso zakho, aze asebenzise iskena ukuthatha umfanekiso wezintso zakho.Kuthathwa iqhekeza elincinci kakhulu lesicwili. Emva koko lihlolwa ngemicroscope ukuze kubonwe ukuba kukho ii-IgA clumps na kunye nokuba umonakalo owenziwe kwizintso ungakanani. Olu vavanyo aluqinisekisi nje kuphela isifo, kodwa lukwanceda ugqirha ukuba akhethe unyango olulungele wena.
Iindlela zonyango kunye nolawulo
Okwangoku akukho nyango lwesi sifo. Kodwa ungakhathazeki! Ngoku kukho unyango olusebenzayo kakhulu olunokulawula esi sifo, lunciphise umonakalo kwizintso, kwaye lukuncede uphile ubomi obusempilweni nobude.
Iinjongo eziphambili zonyango zezi:
- Ukulawula uxinzelelo lwegazi.
- Ukunciphisa ukuphuma kweeprotheyini kumchamo.
- Ukucothisa umonakalo wezintso.
Ngenxa yesi sizathu, ugqirha wakho unokukunika unyango olufana nolu:
- Amayeza oxinzelelo lwegazi: Amayeza afana ne-ACE inhibitors kunye nee-ARB asetyenziswa rhoqo koku. La mayeza awagcini nje ngokulawula uxinzelelo lwegazi, kodwa akwanceda ekukhuseleni izintso.
- Amayeza okuthintela amajoni omzimba: Amayeza e-steroid afana ne-Prednisone okanye amayeza amatsha afana ne-Nefecon anokunikwa ukunciphisa ukudumba kwizintso.
- Amayeza asandul’ ukwaziswa: Amayeza anamhlanje afana neSparsentan (Filspari) kunye ne-Iptacopan (Fabhalta) anceda ekukhuseleni ukusebenza kwezintso ngokunciphisa ukuphuma kweeproteni kumchamo.
- I-Diuretics: Ukuba kukho ukudumba emzimbeni, la mayeza anceda ekususeni amanzi agqithisileyo ngomchamo.
- Amayeza okwehlisa i-cholesterol: Abanye abantu basenokuba namanqanaba aphezulu e-cholesterol. Amayeza afana nama-statins ayanikwa oku.
Utshintsho kwindlela yokuphila lubaluleke kakhulu
Ukongeza kumayeza, utshintsho oluncinci kwindlela ophila ngayo lunokunceda kakhulu ekukhuseleni izintso zakho.
- Nciphisa ukungenisa ityuwa: Nciphisa ubungakanani betyuwa ekutyeni kwakho. Kuphephe ukutya okupakishwe kwiipakethe kunye nezithambisi ezenziweyo. Ezi zinetyuwa eninzi.
- Iproteni yokulawula: Thetha nogqirha wakho okanye ingcali yesondlo ukuze ufumane ubungakanani obufanelekileyo beproteni kuwe. Ukutya iproteni eninzi kubeka uxinzelelo olungakumbi kwizintso zakho.
- Ii-omega-3 fatty acids: Izongezo zeoyile yentlanzi zilungile. Nangona kunjalo, qiniseka ukuba ubuza ugqirha wakho ngaphambi kokuba uthathe naziphi na izongezo.
- Ziphephe iintlungu: Musa ukuzisebenzisa iintlungu ezifana neeNSAID (umz. i-Ibuprofen, iDiclofenac) ngaphandle kwengcebiso kagqirha wakho. Ezi zinokuba yingozi kwizintso zakho.
- Kuphephe ukutshaya: Ukutshaya kunciphisa ukuhamba kwegazi ukuya kwizintso kwaye kunciphisa nokusebenza kakuhle kwamayeza oxinzelelo lwegazi.
- Jonga uxinzelelo lwakho lwegazi rhoqo: Linganisa kwaye ubhale phantsi uxinzelelo lwakho lwegazi ekhaya.
Umyalezo Wokuya Ekhaya
- I-IgA Nephropathy sisifo esihlasela amasosha omzimba esiwonakalisa izintso buthule.
- Xa kuqala njengomkhuhlane, iimpawu zokuqala zisenokuba ngumchamo omnyama (igazi) okanye ukwanda kogwebu kumchamo.
- Esi sifo sinokuqinisekiswa ngokuqinisekileyo kuphela ngokuhlolwa kwezintso.
- Nangona ingenakunyangwa ngokupheleleyo, ngonyango olufanelekileyo kunye notshintsho kwindlela yokuphila, esi sifo sinokulawulwa kwaye ungaphila ubomi obude nobunempilo.
- Ukuba unale mpawu, ungoyiki kwaye ubone ugqirha wakho ngokukhawuleza. Okukhona isifo sifunyanwa ngokukhawuleza, kokukhona amathuba akho okusindisa izintso zakho aba maninzi.
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