Ngaba ngamanye amaxesha uziva utyhafile, ubila, unamehlo aluhlaza, kwaye unesiyezi ? Oku kusenokubangelwa kukwehla ngequbuliso kwamanqanaba eswekile egazini lakho ( hypoglycemia ). Oku kuqhelekile kumntu onesifo seswekile , njengokuthi usela amayeza amaninzi okanye akadli. Kodwa ukuba oku kwenzeka kumntu ongenaso isifo seswekile ngalo lonke ixesha, unobangela usenokuba yinto ongayicingi nokuyicinga. Leyo yimeko engaqhelekanga ekufuneka sonke siyiqaphele, ebizwa ngokuba yi-insulinoma .
Yintoni kanye kanye i-insulinoma?
Ngamafutshane, i-insulinoma sisimila esincinci, esidla ngokuba singesomhlaza esikhula kwi -pancreas yethu . I-pancreas yethu ivelisa i-hormone ebizwa ngokuba yi-insulin. Umsebenzi wale insulin kukulawula ubungakanani beswekile (i-glucose) egazini.
Cinga ngayo, ngesiqhelo xa amanqanaba eswekile emzimbeni wethu enyuka, ipancreas ivelisa i-insulin. Xa amanqanaba eswekile yethu ehla, ayivelisi i-insulin. Kufana nokutshintsha okuvula/ukucima ngexesha elifanelekileyo.
Kodwa xa le tumour ebizwa ngokuba yi-insulinoma ikhula, ivelisa i-insulin rhoqo . Kufana nokuba utshintsho lubambeke kwindawo 'yokuvuka'. Okwenzekayo kukuba i-insulin iyaqhubeka nokuveliswa nokuba amanqanaba eswekile yegazi lethu aphantsi kakhulu. Oku kunokubangela ukuba amanqanaba eswekile yegazi lethu ehle ngendlela eyingozi. Ngenxa yokuba la mathumba enziwe ngohlobo oluthile lweeseli zemithambo-luvo (iiseli ze-neuroendocrine), ugqirha wakho unokuwabiza ngokuba yi-"neuroendocrine tumor". La mathumba adla ngokuba mancinci kakhulu (angaphantsi kwe-intshi enye) kwaye angaphezu kwama-90% angabi ngumhlaza. Ke ngoko, anokunyangwa ngokupheleleyo ngotyando.
Zithini iimpawu zale meko?
Ngenxa yokuba i-insulinoma iqhubeka nokuvelisa i-insulin, iimpawu zibangelwa kukwehla kwamanqanaba eswekile egazini (hypoglycemia). Ezi mpawu zinokuvela ngequbuliso.
| Uphawu | Ingcaciso elula |
|---|---|
| Ukudideka | Ukungakwazi ukuqonda ukuba kwenzeka ntoni, ukuba uphi, kunye nokuziva unesiyezi. |
| Ukubila okugqithisileyo (Ukubila) | Ngequbuliso ndaziva ndibanda kwaye ndibila ngaphandle kwesizathu. |
| Ubuthathaka | Uziva ngathi umzimba wakho ulahlekelwa bubomi bawo, amalungu akho ayathuthumela. |
| Ixhala kunye nokunyuka kwesantya sentliziyo | Uloyiko ngaphandle kwesizathu, uzive ngathi isifuba sakho sibetha ngokukhawuleza. |
| Intloko ebuhlungu kakhulu | Ukuqala ngequbuliso kwentloko ebuhlungu kakhulu. |
| Utshintsho lombono | Izinto ezifana nombono ofipheleyo, umbono ophindwe kabini, njl. |
| Utshintsho kwindlela yokuziphatha | Ukucaphuka ngaphandle kwesizathu, ukucaphuka. |
| Ukuxhuzula | Xa inqanaba leswekile yakho lihla kakhulu, ungashukuma. |
Okubaluleke kakhulu: I-hypoglycemia enzima inokuba yingozi. Inokubangela ukuquleka okanye nokuba yi-coma. Ngoko ke ukuba unale mpawu, bonana nogqirha ngokukhawuleza.
Yintoni ebangela i-insulinoma? Ngubani osengozini enkulu?
Isizathu esichanekileyo sezi thumba asikafunyanwa, kodwa izinto ezithile zinokwandisa umngcipheko.
- Abafazi banotyekelo oluphezulu kancinci kunamadoda.
- Ihlala ifunyanwa kubantu abaphakathi kweminyaka engama-40 ukuya kwengama-60 ubudala .
- Abantu abaneemeko ezithile zofuzo nabo basengozini enkulu. Umzekelo:
- Uhlobo 1 lwe-neoplasia ye-endocrine enininzi: Imeko apho iithumba zenzeka khona kwiindlala ezivelisa iihomoni.
- I-Von Hippel-Lindau syndrome: Yimeko apho iithumba kunye nezakhiwo ezifana nethumba ( ii-cysts ) zenzeka khona kwizitho ezahlukeneyo zomzimba.
- Uhlobo lwe-Neurofibromatosis 1: Ukukhula okungenamhlaza kwimithambo-luvo nakwisikhumba.
- I-Tuberous sclerosis: Iithumba ezingezizo ezomhlaza kwizitho ezifana nengqondo, amehlo, intliziyo, kunye nezintso.
Ugqirha uyifumana njani le nto?
Ukufumanisa i-insulinoma kunokuba nzima kancinci, njengoko iimpawu zifana nezezinye izifo eziqhelekileyo, ngoko ke kungathatha ixesha ukuba ugqirha wakho ayifumanise.
Eyona nto iphambili kukuzila ukutya iiyure ezingama-72 . Kule meko, ugcinwa esibhedlele iintsuku ezimbini ukuya kwezintathu kwaye awuvumelekanga ukutya okanye ukusela nantoni na ngaphandle kwamanzi. Ngeli xesha, oogqirha baya kujonga rhoqo iswekile yakho egazini kunye namanqanaba e-insulin.
Bazama ukuqinisekisa ezi zinto zintathu ngolu vavanyo:
1. Ngaba uneempawu zeswekile ephantsi egazini (ezifana nesiyezi, ukubila).
2. Xa ezo mpawu zibonakala, ngaba iswekile egazini iphantsi ngokwenene?
3. Ngaba iimpawu ziya kuphela xa unika iswekile (iglucose) ngaphandle?
Ukuba une-insulinoma, inqanaba leswekile egazini lakho lokuzila ukutya liza kuba phantsi kakhulu, kodwa inqanaba le-insulin yakho liza kuba phezulu. Olu bubungqina obuphambili. Kunye noku, uvavanyo lwegazi luza kukhangela izinto ezifana ne-`(C-peptide)` kunye ne-`(proinsulin)`.
Emva koko, kwenziwa uvavanyo lokujonga imifanekiso ukuze kufunyanwe apho ikhoyo kanye ithumba le-pancreatic.
- Iskeni ye-CT `(iskeni ye-CT)`
- Iskeni ye-ultrasound `(Ultrasound)`
- Iskeni se-MRI `(MRI)`
Zithini iindlela zonyango zoku?
Unyango oluphambili noluphumelele kakhulu lwe-insulinoma lutyando lokususa ithumba . Kwiimeko ezininzi, esi sifo siyanyangeka ngokupheleleyo emva kotyando.
Uhlobo lotyando olwenziweyo luxhomekeke kuhlobo, ubungakanani, kunye nendawo elikuyo ithumba.
- Ukususa ithumba kuphela: Oogqirha banokususa ithumba ngononophelo ngaphandle kokonakalisa ipancreas.
- Ukususa inxalenye yepancreas: Ngamanye amaxesha inxalenye encinci yepancreas enxulumene nethumba nayo kufuneka isuswe.
Ngobuchwepheshe obuphambili banamhlanje,Ezi thumba zinokususwa nangotyando lwe-laparoscopic. Oku kuthetha ukuba endaweni yokusika okukhulu, utyando lwenziwa ngokusika okuncinci okuliqela ngoncedo lwekhamera. Iingenelo zoku kukuba azibuhlungu kakhulu, inani leentsuku ohlala esibhedlele lifutshane, kwaye ungabuyela kubomi bakho besiqhelo kwangethuba.
Unyango lwezimila ezinomhlaza
Amaxesha amaninzi (ngaphantsi kwe-10%) la mathumba anokuba ngumhlaza. Kwiimeko ezinjalo, unyango luyahluka. Ukuba lonke ithumba alinakukwazi ukususwa ngotyando, kunokufuneka uthathe amayeza okuthintela iswekile egazini ukuba ingabi phantsi kakhulu. Ungadinga ne-chemotherapy . Kwezinye iintlobo zomhlaza, kukho unyango olukhethekileyo, olufana ne-"Lutetium Lu 177 dotatate", olubandakanya ukunika iyeza elinomhlaza ngemithambo yegazi.
Ngaba kukho naziphi na iingxaki emva kotyando?
Nangona utyando luphumelela kwiimeko ezininzi, njengakuyo nayiphi na indlela yotyando, kukho umngcipheko weengxaki ezincinci.
- Ukopha
- Usulelo
- Intlungu
- Ukuba inxalenye enkulu yepancreas isusiwe, kukho umngcipheko wokuba nesifo seswekile.
- Ukuvuza kolwelo oluvela kwipancreas (i-Pancreatic fistula)
- Ukuncipha kwee-enzymes zokugaya ukutya.
Ukuba sisimila esinomhlaza, iingxaki ezifana nesifo esisasazeka kwamanye amalungu omzimba (i-metastasis) zinokwenzeka. Ugqirha wakho uza kukuchazela oku ngokweenkcukacha.
Umyalezo Wokuya Ekhaya
- I-Insulinoma sisimila esingaqhelekanga esikhula kwi-pancreas. Oku kubangela ukuba amanqanaba eswekile egazini abe phantsi rhoqo.
- Ukuba ufumana iimpawu ezingalindelekanga ezifana nesiyezi, ukubila kakhulu, kunye nokudideka ngaphandle kwesizathu esicacileyo, ingakumbi xa ulambile, bonana nogqirha ngokukhawuleza.
- Ukuxilongwa kufuna ukuhlala esibhedlele kunye novavanyo lwegazi olukhethekileyo kunye neeskeni.
- Unyango oluphambili kukususwa kwesi sifo ngotyando, nto leyo edla ngokubangela ukuba siphile ngokupheleleyo.
- Uninzi lwee-insulinomas azinawo umhlaza, ngoko ke akukho mfuneko yokoyika. Nangona kunjalo, qiniseka ukuba uqhagamshelana nogqirha wakho ukuze ufumane ukuxilongwa ngokuchanekileyo kunye nonyango.
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