Okudingeka ukwazi ngama-androgens!

Wake wezwa ngama-androgen? Mhlawumbe yebo, mhlawumbe cha. Kodwa ayiqembu lama-hormone akhona kuyo yonke imizimba yethu futhi abaluleke kakhulu ekukhuleni kwethu ngokocansi kanye nempilo yethu. Lawa ma-androgen afana nezinceku ezincane ezisebenza ngemuva kwezigcawu emizimbeni yethu. Namuhla, sizokhuluma ngawo ngendlela elula ongayiqonda.

Kalula nje, ama-androgens awuhlobo lwama-hormone ocansi. Yiwona asenza sivuthwe, futhi asiza empilweni yesimiso sethu sokuzala kanye nokukhula kwemizimba yethu. Ungase ucabange ukuthi amadoda kuphela anawo. Kodwa empeleni, sonke, kungakhathaliseki ukuthi abesilisa noma abesifazane, sinama-androgens emizimbeni yethu. Kodwa-ke, akhiqizwa ngokwemvelo ngamanani aphezulu kwabesilisa. I-Testosterone, abaningi bethu esike sezwa ngayo, nayo iyi-androgen enkulu.

Manje ungase uzibuze ukuthi lawa ma-hormone avelaphi. Ama-Androgen akhiqizwa kakhulu ngama-testicles ohlelweni lokuzala lwabesilisa kanye nama-ovari ohlelweni lokuzala lwabesifazane. Ngaphezu kwalokho, lawa ma-hormone akhiqizwa nezindlala ze-adrenal ezitholakala ngaphezu kwezinso zethu. Ama-Androgen awagcini lapho. Asebenza kahle kakhulu ekugcineni intuthuko yethu yocansi kanye nempilo iyonke. Amazinga awo angashintsha usuku lonke. Futhi, lawa mazinga ama-hormone ayashintsha ezigabeni ezahlukene zokuphila kwethu, njengasesikhathini sokuthomba kanye nokunqamuka kokuya esikhathini.

Yiziphi izinhlobo zama-androgens ezikhona?

Njengoba sishilo ngaphambili, i-testosterone iyi-androgen eyinhloko esinayo sonke. Amanye ama-androgen amaningi asiza ekwenzeni amanye ama-hormone. Isibonelo, ama-androgen alandelayo asiza ekwenzeni i-testosterone ne-estrogen:

• I-Androstenedione
• I-Dehydroepiandrosterone (DHEA)
• I-DHEA sulfate (DHEA sulfate - DHEAS)

Enye i-androgen yi- dihydrotestosterone (DHT) . Njengoba ukhula, umzimba wakho uguqula cishe u-10% we-testosterone yakho ibe yi-DHT nsuku zonke. Ngaphezu kwalokho, kunezinye izinhlobo eziningi ze-androgen kanye namakhemikhali amaningi ahlobene ne-androgen. Indlela imizimba yethu esebenzisa ngayo la ma-hormone iyinkimbinkimbi kakhulu, njengomshini omkhulu.

Iyiphi inkonzo enikezwa yi-androgens emizimbeni yethu?

Ama-Androgens kithi sonke, kungakhathaliseki ubulili, asiza ngalezi zinto:

• Ubuningi bamathambo: Lokhu kubalulekile ukuze amathambo ethu aqine.
• Ukukhula kwemisipha: Lokhu kuyadingeka nasekukhuleni kwemisipha .
• Ukuthomba: Lezi yizinguquko eziyisisekelo ezenzeka kusukela ebuntwaneni kuya ekubeni umuntu omdala.
• Ukukhiqizwa kwamangqamuzana abomvu egazi (i-Erythropoiesis): Kuphinde kusize ekukhiqizweni kwamangqamuzana abomvu egazi emizimbeni yethu.
• Isifiso socansi kanye nomsebenzi: Lokhu kuthinta ukuthuthukiswa kwemizwa yocansi kanye nomsebenzi wocansi.

Kwenzekani ngqo emadodeni ane-androgens?

Ama-Androgens emzimbeni wesilisa anegalelo ku:

• Izwi elijulile (ukwelula intambo yezwi): Izwi elithambile owawunalo usengumntwana liyashintsha, futhi izwi lowesilisa liyavela ngenxa yalokhu. Cabanga nje, indodana yomngane wakho ishintsha izwi layo ngokuzumayo, bese ucabanga ukuthi, "Mfowethu, usengumfana omkhulu manje," akunjalo? Isizathu salokho yi-androgens.
• Ukuphakama: La ma-hormone nawo athinta ukuphakama.
• Ukukhula kwezinwele ebusweni, ekhanda, esifubeni, emakhwapheni nasezindaweni zangasese: Izinto ezifana nokukhula kwentshebe nokukhula kwezinwele esifubeni.
• Ukukhula kwesidoda: Lokhu kubalulekile ekukhiqizeni isidoda esidingekayo ukuze kwakheke umntwana.

Lezi zici zomzimba ngokuvamile ziqala ngesikhathi sokuthomba. Kodwa i-testosterone inemisebenzi ehlukene ezigabeni ezahlukene zokuphila. Njengoba uba umuntu omdala, amazinga akho e-testosterone ayancipha ngokwemvelo njengoba ukhula.

Ama-androgens abathinta kanjani abesifazane?

Kwabesifazane, amanye amakhemikhali omzimba aguqula i-androgen testosterone ibe yi -estradiol, uhlobo lwe-hormone i-estrogen . Le estradiol:

• Ukuthuthukiswa kwezici zocansi zesibili ngesikhathi sokuthomba: isibonelo, ukukhula kwamabele kanye nokwandiswa kwezinqe.
• Ilawula ukuya esikhathini: Isiza ukugcina umjikelezo wokuya esikhathini ojwayelekile.
• Kusiza ekukhulelweni nasekukhulelweni: Lokhu kubalulekile ekukhulelweni nasekukhulelweni ngempumelelo.
• Kunciphisa ukulahleka kwamathambo - I-Osteoporosis: Kusiza ekunciphiseni ingozi ye -osteoporosis , okuyisimo esenzeka lapho amathambo ephuka, ikakhulukazi njengoba sikhula.

Amazinga e-estradiol emzimbeni wakho ayashintsha ngezigaba ezahlukene empilweni yakho. Ngemva kokunqamuka kokuya esikhathini, okuyilapho ukuya kwakho kwanyanga zonke kuyeka khona, umzimba wakho awukhiqizi i-estradiol eningi kangako.

Yiziphi izinkinga amadoda anazo ngama-androgens?

Amadoda avame ukuthinteka kakhulu yisimo esibizwa ngokuthi i-hypogonadism yabesilisa, okuwukwehla kwamazinga e-androgen, noma amazinga e-testosterone. Lokhu kungaholela ekunciphiseni isifiso sobulili kanye nokungasebenzi kahle kwe-erectile.Izimpawu ezinjengokuthi: Uma unesifo esifana nalesi, kubaluleke kakhulu ukukhuluma nodokotela ngaphandle kokusigcina kuwe futhi ungakhathazeki.

Kwabanye abantu, ama-androgen angabangela umdlavuza wendlala . Ezimweni ezinjalo, kungadingeka ukuthi uthathe imithi yokunciphisa ukukhiqizwa kwemvelo kwama-androgen emzimbeni. Odokotela babiza lokhu kwelashwa ngokuthi i-Androgen Deprivation Therapy (ADT) .

Ama-Androgens – ikakhulukazi i-DHT (i-Dihydrotestosterone) – nawo ahlotshaniswa nokuba nempandla kwabesilisa , isimo esibizwa ngokuthi i-androgenic alopecia . Lawa ma-hormone aphinde abe nomthelela ekubeni nempandla abantu abaningi abakubiza ngokuthi 'ukugcwala'.

Yiziphi izinkinga abesifazane abanazo ngama-androgens?

Abesifazane bathinteka kakhulu yizinkinga zokwanda kwamazinga e-androgen (hyperandrogenism) . Imbangela enkulu yalokhu yisimo esibizwa ngokuthi i-Polycystic Ovary Syndrome (PCOS) . Le PCOS yinto ebonakala kwabesifazane abaningi kulezi zinsuku. Ubuwazi ukuthi i-PCOS ngezinye izikhathi ingabangela ukukhulelwa okulibazisekile? Akuvamile ukuthi amazinga e-androgen nawo akhuphuke ngenxa yezimila ezindlaleni ze-adrenal noma kuma-ovari.

Abantu abane-PCOS, noma labo abanamazinga aphezulu e-androgens, bangase babe nezimpawu ezifana nalezi:

• Izinduna: Kuvela amaqhubu ebusweni, esifubeni nasemhlane. Ngezinye izikhathi la maqhubu angaba yinto ecasulayo kakhulu.
• I-Amenorrhea noma ukuya esikhathini okungajwayelekile: Ukuya esikhathini okungenzeki ngesikhathi esifanele, noma okubambezeleka izinyanga.
• Ukukhula kwezinwele ngokweqile (i-hirsutism): Ukukhula kwezinwele okungafunwa esilevini, esifubeni, nasesiswini, njengendevu. Lokhu kungathinta nabesifazane abaningi ngokwengqondo.
• Umfutho wegazi ophezulu kanye ne-cholesterol ephezulu.
• Ubunzima bokuthola abantwana (Ukungazali).
• Ukukhuluphala: Ukukhuluphala ngokweqile.

Ama-Androgens – ikakhulukazi i-DHT (i-Dihydrotestosterone) – angathinta nempandla yabesifazane. Abanye besifazane nabo babhekana nokulahlekelwa izinwele okunamabala kanye nekhanda elinoboya obunamabala, akunjalo? Le hormone nayo inomthelela kulokho.

Yiziphi izinkinga ezingavela ngenxa yamazinga e-androgen ezinganeni ezincane?

Izinkinga ngamazinga e-androgen ezinganeni zingaholela ekuthombeni okulibazisekile noma ekuthombeni ngaphambi kwesikhathi.Yebo, kungenzeka. Kungaba nezizathu eziningana zalokhu ngakunye. Isibonelo, ezinye izingane zibonisa izimpawu zokuthomba kusenesikhathi kakhulu kunezinye. Kanti ezinye izingane azifinyeleli ekuthombeni ngisho nangemva kokufika ekuthombeni. Zombili lezi yizimo ezidinga ukunakekelwa kwezokwelapha.

Amazinga e-androgen nawo ahlotshaniswa nezimo ezibizwa ngokuthi ukuphazamiseka kokukhula kocansi . Lokhu kubhekisela eqenjini lezimo ezingaba ngu-60 ezahlukene lapho umuntu enezici zowesilisa nowesifazane. Lezi yizimo eziyinkimbinkimbi kancane, ngakho zidinga ukunakekelwa okukhethekile kodokotela.

Odokotela balinganisa kanjani amazinga e-androgen?

Ukuhlola ukuthi owesifazane unamazinga aphezulu e-androgen, odokotela bavame ukusebenzisa ukuhlolwa okubizwa ngokuthi i-Free Androgen Index (FAI) . I-FAI ilinganiswa ngokuthatha isampula yegazi bese ilinganisa okulandelayo:

• I-testosterone ephelele
• I-testosterone yamahhala
• I-globulin ebopha ama-hormone ocansi (SHBG)

I-SHBG iyiprotheni ephethe ama-androgen (njenge-testosterone ne-DHT) kanye ne-estrogen egazini. Udokotela wakho uzobala amazinga akho e-androgen ngokuqhathanisa amazinga akho e-testosterone ne-SHBG.

Kwabesilisa, odokotela bavame uku-oda ukuhlolwa kwegazi le-testosterone ukuze kuhlolwe amazinga e-testosterone aphansi.

Kodwa khumbula, lokhu kuhlolwa kwegazi kuphela akukwazi ukukutshela konke. Udokotela wakho uzokwenza isinqumo ngokusekelwe ezintweni eziningi, okuhlanganisa izimpawu zakho kanye nokuhlolwa kwezokwelapha.

Ngakho-ke, yimuphi umyalezo okufanele siwuthathe siwuyise ekhaya kukho konke lokhu?

Ama-Androgen abalulekile empilweni yokuzala kanye nenhlalakahle yethu sonke, abesifazane, amadoda, abasha nabadala. Kodwa ukuze lokhu kusebenze kahle, kudingeka kube nokulinganisela okufanele . Njengesikali, uma sisinda kakhulu ohlangothini olulodwa, kunenkinga. Uma kuncane kakhulu, kunenkinga; uma kuningi kakhulu, kunenkinga.

Uma unezimpawu zamazinga aphansi noma aphezulu e-androgen, isibonelo, njengoba kushiwo ngaphambili, ukuntuleka kwesifiso sobulili, ubunzima bokuqiniswa kwabesilisa, ukuya esikhathini okungajwayelekile, ukukhula kwezinwele ngokweqile, induna kwabesifazane, noma ukubambezeleka noma ukuthomba kwengane ekuqaleni, qiniseka ukuthi ubona udokotela ukuze akunike iseluleko . Udokotela angenza izivivinyo ezidingekayo futhi athole ukuthi yini ngempela ebangela izimpawu zakho. Ungakhathazeki, kuvame ukuba nezindlela zokwelapha ezinhle zalokhu.

Khumbula, wazi umzimba wakho kangcono. Uma ubona noma yiziphi izinguquko noma ukungajwayelekile, kuwukuhlakanipha ukufuna iseluleko sezokwelapha kunokusishaya indiva.

Ama - Androgens, i-Testosterone, amaHormones, Impilo Yokuzala, i-PCOS, Impilo Yabesilisa, Impilo Yabesifazane