Iyini i-estrogen? Ibaluleke kangakanani emzimbeni wakho?

Cishe uke wezwa igama elithi `Estrogen`, akunjalo? Ikakhulukazi njengowesifazane, i-`Estrogen` ihilelekile ezintweni eziningi empilweni yakho. Kalula nje, iyisithunywa samakhemikhali esibaluleke kakhulu emzimbeni wethu, i-hormone. Ake sixoxe kabanzi nge-`Estrogen`, akunjalo?

Ingabe zikhona izinhlobo ze-estrogen?

Yebo, kunezinhlobo ezintathu eziyinhloko ze-estrogen. Yilezi:

• I-Estrone (E1): Lolu uhlobo oluyinhloko lwe-estrogen olukhiqizwa emzimbeni wakho ngemva kokunqamuka kokuya esikhathini.
• I-Estradiol (E2): Lolu uhlobo oluyinhloko nolunamandla kakhulu lwe-estrogen emzimbeni wakho ngesikhathi sakho sokuzala, lapho ungaba nabantwana.
• `Estriol (E3): Lolu hlobo lwe-`Estrogen` uhlobo oluyinhloko lwe-hormone olusebenzayo uma ukhulelwe.

Iyini indima ye-estrogen empilweni yokuzala yabesifazane?

I-estrogen, njengamanye ama-hormone, iyisithunywa samakhemikhali esithumela imiyalezo emizimbeni yethu. Isitshela ukuthi siqale futhi siyeke izinqubo ezihlobene nempilo yakho yocansi kanye nokuzala. Lezi zinqubo zibangela izinguquko ezibalulekile emzimbeni wakho.

Ukuthomba

Njengoba udlula esikhathini sokuthomba, amazinga akho e-estrogen ayanda. Lokhu kwanda yikho okubangela ukuba kuvele izici zocansi zesibili, njengokukhula kwamabele kanye nokukhula kwezinqe.

Umjikelezo wokuya esikhathini

I-estrogen, kanye nama-hormone akhiqizwa ubuchopho bakho (i-FSH ne-LH) kanye ne-progesterone, kudlala indima enkulu ekugcineni umjikelezo wakho wokuya esikhathini ujwayelekile . Wonke la ma-hormone asebenza ngokulinganisela okubucayi. I-estrogen isiza ngokukhishwa kweqanda emaqanda akho, futhi iqinisa ulwelwesi lwesibeletho sakho (i-endometrium) ukuze ilungiselele ukukhulelwa.

Ukukhulelwa kanye nokuzala

Ezinsukwini ezimbalwa ngaphambi kokukhishwa kweqanda, amazinga e-estrogen ayanda. Lesi yisikhathi sakho sokuzala. Ngesikhathi esifanayo, i-estrogen inciphisa ulwelwesi lomlomo wesibeletho. Yile ngwenya lapho isidoda kufanele sibhukude khona ukuze sihlangane neqanda. Ngakho-ke, lezi zinguquko ezibangelwa i-estrogen zenza kube lula ngawe ukukhulelwa.

Futhi, kungakhathaliseki ukuthi ukusiphi isigaba somjikelezo wakho wokuya esikhathini, ukuba khona kwe-estrogen kwenza kube lula ukuya ocansini. Kusiza ukugcina izindonga zesitho sangasese sowesifazane zijiyile, ziguquguquka, futhi zimanzi, okunciphisa ubuhlungu ngesikhathi socansi.

Ukunqamuka kokuya esikhathini

Ngaphambi nje kokunqamuka kokuya esikhathini, okubizwa ngokuthi i-perimenopause, amazinga e-estrogen ayehla. Lesi sikhathi singahlala iminyaka eminingana. Ukunqamuka kokuya esikhathini kuqala ngokusemthethweni uma uyeka ukuya esikhathini izinyanga eziyi-12. Lokhu kuvame ukwenzeka cishe eminyakeni engu-51. Ngokunqamuka kokuya esikhathini, amazinga akho e-estrogen ayehla bese uyeka ukukhiqiza amaqanda. Lokhu kwehla kwe-estrogen kungabangela izimpawu ezifana nokoma kwesitho sangasese sowesifazane, ukushintshashintsha kwemizwa, ukujuluka ebusuku, kanye nokushisa okukhulu .

Phakathi nalesi sikhathi, i-estrogen eyinhloko emzimbeni wakho ishintsha isuka ku-Estradiol (E2) iye ku-Estrone (E1).

I-estrogen iyithinta kanjani impilo yokuzala yabesilisa?

Ungamangali, i-estrogen ithinta nempilo yokuzala yamadoda. Ithinta isifiso socansi, ukuvuka, kanye nokukhiqizwa kwesidoda.

Amazinga aphansi e-estrogen angabangela ukwehla kwesifiso sobulili. Amazinga aphezulu angabangela ukungazali kanye nokungasebenzi kahle kwe-erectile. Amazinga aphezulu e-estrogen angabangela nokukhula kwamabele (gynecomastia).

Uma ungumuntu wesilisa futhi ukhathazekile ngamazinga akho e-estrogen, kuwumqondo omuhle ukubonana nodokotela we-endocrinologist noma uchwepheshe wezokwelapha ezisebenzayo.

Yimiphi eminye imisebenzi i-estrogen enayo engahlobene nokuzala?

I-estrogen ilawula izinqubo ezibalulekile ohlelweni lwamathambo, uhlelo lwenhliziyo nemithambo yegazi, kanye nohlelo lwezinzwa oluphakathi oluthinta impilo yakho iyonke. Lokho kusho ukuthi:

• Amazinga e-cholesterol
• Amazinga kashukela egazini
• Isisindo samathambo nemisipha
• Ukujikeleza kwegazi kanye nokugeleza kwegazi
• Umswakama wesikhumba kanye nokukhiqizwa kwe-collagen
• Umsebenzi wobuchopho, okuhlanganisa nekhono lakho lokugxila

I-estrogen ikhiqizwa kuphi emzimbeni?

Phakathi neminyaka yakho yokuzala, iningi le-estrogen yakho likhiqizwa ama-ovari akho. I-estrogen ikhiqizwa futhi yizindlala zakho ze-adrenal (izindlala ezitholakala ngaphezu kwezinso zakho) kanye nezicubu zamafutha. Ngesikhathi sokukhulelwa, i-estrogen nayo ikhishwa yi-placenta (isitho esishintshanisa izakhamzimba phakathi kukamama nomntwana osanda kuzalwa).

Ngemva kokukhishwa, i-'Estrogen' ihamba ngegazi bese iya engxenyeni yomzimba lapho kudingeka isebenze khona. Lapho, ibopha iphrotheni ebizwa ngokuthi i-'Estrogen', okuyi-'Estrogen receptor', bese inqubo iqala. Lawa ma-'Estrogen receptors' akhona emzimbeni wakho wonke.

Yiziphi izimo ezivamile ezihlobene ne-estrogen?

I-estrogen inomthelela ezimweni eziningi ezihlobene nempilo yabesifazane. Ezinye zazo yilezi:

• I-Anorexia nervosa: Kulezi zimo, amazinga e-estrogen aphansi. Uma amazinga e-estrogen ephansi, ukuya esikhathini kungaba okungajwayelekile noma kume ngokuphelele (i-amenorrhea). Abantu abanamafutha omzimba aphansi kakhulu (amamodeli, abasubathi) noma labo abanezindlela zokudla ezingajwayelekile nabo bangaba namazinga e-estrogen aphansi.
• Umdlavuza webele: Ukuba namazinga aphezulu e-estrogen isikhathi eside (ngokwemvelo noma kwezinye izindlela zokuvimbela inzalo, ukwelashwa kokufaka esikhundleni sama-hormone (HRT)) kungandisa ingozi yakho yomdlavuza webele. Kukhona kokubili izinzuzo nezingozi ku-HRT. Ungakhuluma nodokotela wakho ukuze unqume ukuthi izinzuzo ze-HRT zidlula yini izingozi.
• I-Endometriosis: I-Estrogen ayibangeli i-endometriosis, kodwa ubuhlungu obubangelwa i-endometriosis bungandiswa yi-estrogen.
• Ukungasebenzi kahle kocansi kwabesifazane (FSD): Ukwehla kwamazinga e-estrogen kungabangela izinguquko zomzimba nezengqondo ezenza ucansi lungajabulisi. Kodwa-ke, i-estrogen ayicatshangelwa ukwelashwa kokushintsha ama-hormone uze ufike esikhathini sokunqamuka kokuya esikhathini.
• Amabele ane-fibrocystic: Izicubu zakho zebele zingase zizwe zinobuthi, zibuhlungu, noma zingakhululekile ngenxa yezinguquko emazingeni e-estrogen ngesikhathi sokuya esikhathini.
• Ukungazali: Amazinga aphansi noma aphezulu e-estrogen angaphazamisa umjikelezo wakho wokuya esikhathini. Izimo eziyisisekelo ezibangela amazinga aphansi noma aphezulu e-estrogen nazo zingahlotshaniswa nokungazali.
• Ukukhuluphala: Abantu abanamafutha amaningi emzimbeni bavame ukuba namazinga aphezulu e-estrogen.
• I-Osteoporosis: Amazinga aphansi e-estrogen angabangela ukuba amathambo akho abe buthakathaka futhi aphuke kalula.
• I-Polycystic ovary syndrome (PCOS): I-PCOS yisimo lapho ama-ovari ekhiqiza khona ama-hormone wesilisa amaningi (ama-androgens). Ngezinye izikhathi, ku-PCOS, amazinga e-estrogen angaba phezulu uma kuqhathaniswa namazinga e-progesterone.
• Ukungasebenzi kahle kwesibeletho (ukunqamuka kokuya esikhathini ngaphambi kwesikhathi): Kulesi simo, ama-ovari ayayeka ukukhiqiza amaqanda ngaphambi kweminyaka engama-40. Ngakho-ke, ama-ovari awakhiqizi i-estrogen edingwa ngumzimba wakho.
• I-Premenstrual syndrome (PMS) kanye ne-premenstrual dysphoric disorder (PMDD):Izinguquko zamahomoni ezihambisana nokuya esikhathini zingabangela izimpawu zomzimba ezingathandeki kanye nokushintshashintsha kwemizwelo. Ukwehla kwamazinga e-estrogen ngemva kokukhishwa kweqanda kungabangela i-PMS kanye ne-PMDD.
• I-Turner syndrome: Abantu abane-Turner syndrome bavame ukuba nama-ovari angakakhuli kahle, okusho ukuthi banamazinga aphansi e-estrogen. Lokhu kusho ukuthi uma unalesi simo, ungase ungabi namabele noma ungasayi esikhathini.
• Umdlavuza wesibeletho (umdlavuza we-endometrial): Amazinga e-estrogen akhuphukayo angabangela ukuthi ulwelwesi lwesibeletho sakho luqine. Ngokuhamba kwesikhathi, amangqamuzana omdlavuza angaqala ukukhula.
• Ama-fibroid esibeletho nama-polyp: I-estrogen eningi kakhulu ingahlotshaniswa nokukhula okungenawo umdlavuza (ama-fibroid) noma ama-polyp (ama-polyp) akhula esibelethweni sakho.
• Ukoma kwesitho sangasese sowesifazane (i-vaginal atrophy - i-atrophic vaginitis): Ngenxa yokwehla kwe-estrogen, ulwelwesi lwesitho sangasese sowesifazane lungaba luncane futhi lome. Lokhu kuvamile ngesikhathi sokunqamuka kokuya esikhathini kanye nangemva kokunqamuka kokuya esikhathini.

Indima ye-estrogen ezimweni ezithinta ezinye izinhlelo zomzimba isacwaningwa. Isibonelo, i-estrogen ihlotshaniswa nezinye izifo ze-endocrine kanye nezifo zesisu.

Angakanani amazinga ajwayelekile e-estrogen?

Amazinga e-estrogen ayakhuphuka futhi ehla kuyo yonke impilo. Lokhu kuguquguquka kuvamile. Isibonelo, kuvamile ukuthi amazinga e-estrogen akhuphuke ngesikhathi sokuthomba futhi ehle njengoba usondela ekunqamukeni kokuya esikhathini. Amazinga e-estrogen ayanda ngesikhathi sokuvuthwa kweqanda ukusiza ukulungiselela umzimba wakho ukukhulelwa. Kuvamile futhi ukuthi amazinga e-estrogen ehle ngesikhathi sokuya esikhathini, njengoba izinguquko ezihlobene nokukhulelwa zingasadingeki.

Uma amazinga akho e-estrogen ephansi noma ephezulu njalo, kungaba uphawu lwesifo esithile esiyimfihlo. Kufanele ukhulume nodokotela wakho ngakho.

Kwenzekani uma amazinga e-estrogen ehla njalo?

Amazinga aphansi e-estrogen avame ukuba uphawu lokuthi ususondela ekunqamukeni kokuya esikhathini. I-estrogen ephansi ingabonisa nezinkinga zokuzala, ukuntuleka kokudla okunempilo, kanye nezimo ezifana ne-Turner syndrome.

Lezi zingabonakala njengezimpawu:

• Ubuhlungu bebele
• Amathambo noma amathambo abuthakathaka aphuka kalula
• Ukushisa okukhulu kanye nokujuluka ebusuku
• Ukuya esikhathini okungajwayelekile noma ukuyeka ngokuphelele ukuya esikhathini
• Ikhanda elibuhlungu, ubunzima bokugxila
• Ukukhathala, ukozela, ukuqwasha
• Ukushintshashintsha kwemizwa, ukucasuka, nokucindezeleka
• Ukoma kwesitho sangasese sowesifazane, okubangela ubuhlungu ngesikhathi socansi (i-Dyspareunia)

Kwenzekani uma amazinga e-estrogen ehlala ephezulu?

Ukuba ne-estrogen eningi emzimbeni wakho kungahlotshaniswa nezimo ezahlukahlukene, okuhlanganisa ama-polyps, ama-fibroids, i-PCOS, i-endometriosis, kanye nama-cyst esibeletho. Amazinga akho e-estrogen angakhuphuka ngoba une-estrogen eningi kakhulu uma kuqhathaniswa nelinye i-hormone yakho yobulili, i-progesterone. Imithi equkethe i-estrogen ingandisa ne-estrogen emzimbeni wakho.

Lezi zingabonakala njengezimpawu:

• Ukuncipha kwesifiso sobulili
• Ukwanda kwesisindo, ikakhulukazi okhalweni nasezinqeni
• Ukuya esikhathini okungajwayelekile (ukopha ngezikhathi ezingalindelekile, okuncane noma ngaphezulu)
• Ukuwohloka kwezimpawu ezihambisana ne-PMS noma i-PMDD

Ngingazi kanjani amazinga ami e-estrogen?

Ukuhlolwa kwe-estrogen kungalinganisa amazinga akho e-Estrone (E1), i-Estradiol (E2), noma i-Estriol (E3). Udokotela wakho uzokwenza ukuhlolwa kwegazi okulula bese ekuthumela elebhu ukuze kuhlaziywe.

Yiziphi izindlela zokwelapha ezivamile zezifo ezihlobene ne-estrogen?

Ukwelashwa kokushintsha ama-hormone (HT) kuyindlela yokwelapha evamile kwabesifazane abanamazinga aphansi e-estrogen, ikakhulukazi labo abadlula esikhathini sokunqamuka kokuya esikhathini. Nge-HT, udokotela wakho uzokunikeza imithamo ephansi ye-estrogen noma inhlanganisela ye-estrogen ne-progesterone (noma uhlobo lwe-progesterone yokwenziwa, olubizwa ngokuthi i-progestin). Kodwa-ke, i-HT inezingozi, futhi ayilungele wonke umuntu. Khuluma nodokotela wakho mayelana nokuthi i-HT ikulungele yini.

Ungawagcina kanjani amazinga e-estrogen anempilo?

Izimo ezihlobene nokungalingani kwama-hormone azikwazi ukuvinjelwa ngaso sonke isikhathi. Kodwa-ke, kunemikhuba emihle ongayilandela ezokusiza ukugcina impilo yakho iyonke:

• Lala ngokwanele: Ukulala ngokwanele, okungaphazanyiswa njalo ebusuku kusiza umzimba wakho ukuthi ugcine amazinga ama-hormone anempilo adingekayo ukuze wenze imisebenzi ebalulekile.
• Lawula ukucindezeleka: Ukucindezeleka ngokweqile kungabangela umzimba wakho ukuthi ukhiqize ama-hormone amaningi okucindezeleka `(Cortisol)` kanye `(Adrenaline).` La ma-hormone okucindezeleka ngokweqile angabangela ukungalingani kwama-hormone okuthinta kabi amazinga `(Oestrogen)`.
• Thola isilinganiso esifanele sokuzivocavoca: Ukuzivocavoca okunempilo kungakusiza ukuthi ulawule imikhuba yakho yokudla kanye namafutha omzimba. Kungakusiza futhi ukuthi ulale kangcono.
• Nciphisa ukusetshenziswa kotshwala: Utshwala bungakhuphula amazinga e-estrogen yakho. Ukuchayeka isikhathi eside ku-estrogen kungandisa ingozi yakho yokuba nomdlavuza.
• Landela imikhuba emihle yokudla:Ukuze ulinganisele ama-hormone akho, qaphela lokho okudlayo. Ukunciphisa ukudla okunoshukela nokudla ukudla okune-fiber eningi namafutha anempilo (atholakala kumafutha omnqumo, amantongomane, nenhlanzi) kungasiza ekulinganiseni ama-hormone.

Into ebaluleke kakhulu okufanele uyikhumbule (Umyalezo Wokuya Ekhaya)

I-estrogen ibalulekile empilweni yakho yokuzala kanye nempilo yakho iyonke. Kujwayelekile ukuthi amazinga e-estrogen ashintshe ngokweminyaka yakho kanye nomjikelezo wakho wokuya esikhathini. Kodwa-ke, uma amazinga akho ehlala ephakeme noma ephansi, ungase ube nezimpawu ezingathandeki. Kubalulekile ukukhuluma nodokotela wakho ngalokhu. Ngokuvamile kunezindlela zokwelapha ezingasiza, njengokulawula ukubeletha, ukushintsha indlela yokuphila, noma ukwelashwa ngama-hormone ngemva kokunqamuka kokuya esikhathini.

Ngakho-ke, naka izinguquko emzimbeni wakho, futhi uma unenkinga, ungabi namahloni futhi ukhulume nodokotela. Impilo yakho ibaluleke kakhulu kuwe!

I- Estrogen, ama-hormone, impilo yabesifazane, impilo yokuzala, umjikelezo wokuya esikhathini, ukunqamuka kokuya esikhathini, ukukhulelwa