Uke wezwa ngalolu hlobo lwesimila esikhula emaqanda? (I-Granulosa Cell Tumor) Ake sixoxe ngakho!

Kungenzeka ukuthi awukaze uzwe leli gama ngaphambili – I-Granulosa Cell Tumor uhlobo olungavamile lwesimila olungakhula emaqanda abesifazane. Kodwa ungesabi uma uzwa igama, kulungile? Sizokhuluma ngalokhu kalula, ukuze ukwazi ukukuqonda. Ngoba, kubaluleke kakhulu ukwazi nganoma yini.

Kuyini i-Granulosa Cell Tumor? Masiqonde kalula!

Kalula nje, lesi `(Granulosa Cell Tumor)` siyisimila esikhethekile (isimila) esikhula emaqanda ethu besifazane . Amaqanda, njengoba wazi, ayilungu elibaluleke kakhulu emzimbeni wethu elikhiqiza amaqanda futhi likhiqiza nama-hormone wesifazane njenge-`(Estrogen)` kanye ne-`(Progesterone). Lolu hlobo lwesimila, uma sikhuluma iqiniso, lungolwesigaba se-`(sex cord-stromal tumor)`. Lapho lesi simila sikhula, izinga le-`(Estrogen)` emzimbeni livame ukwanda kakhulu . Nakuba lokhu kungakhula kunoma yimuphi ubudala, kuvame ukubonakala cishe eminyakeni engu-50.

Lawa mathumba akheka kuphi?

Ama-Granulosa cell tumors (GCTs) akhula kuma-ovari . Ama-ovari ayingxenye yesistimu yokuzala yabesifazane. Ngaphezu kokukhiqiza amaqanda (ama-ovari), ama-ovari akhiqiza nama-hormone okuzala i-estrogen ne-progesterone.

Zivame kangakanani lezi zinto?

Empeleni lezi azivamile kakhulu , ezibizwa ngokuthi "ama-Granulosa Cell Tumors". Zakha cishe u-5% wezimila eziyinhloko zesibeletho. Ngakho-ke, njengoba ubona, lokhu akuvamile kangako.

Ingabe lokhu kubangelwa umdlavuza? Noma amathumba nje?

Umbuzo omkhulu kubantu abaningi ukuthi ngabe lokhu kungumdlavuza oyingozi noma umane nje uyisimila. Eqinisweni, lawa mathumba eseli le-granulosa cishe ayingozi, noma anomdlavuza .

Kodwa, kunezindaba ezinhle lapha. Lezi zinhlobo zamathumba (GCT) zivame ukukhula kancane kakhulu . Okusho ukuthi, azisabalali ngokushesha. Ngakho-ke, odokotela bangazibona kusenesikhathi, bese amathuba okuthola imiphumela emihle ekwelashweni aphezulu.

Ingabe ukhona umehluko phakathi kwe-Granulosa Cell Tumor kubantu abadala kanye nabantu abasha?

Yebo, kunomehluko omncane lapha. Lawa mathumba avame ukubonakala kwabesifazane asebekhulile. Eqinisweni, ama-95% azo zonke izifo ze-GCT ezitholakale zitholakala kwabesifazane asebekhulile abakhule kahle .

Kodwa-ke, akuvamile, uma lesi simila sikhula kumuntu ongaphansi kweminyaka engama-30, sibizwa ngokuthi i-juvenile granulosa cell tumor (JGCT) . Lolu hlobo lwesimila esikhula kubantu abasebasha, uma sisakazeke ngaphandle kwesibeletho, ngezinye izikhathi luvame ukuphinda lubuye eminyakeni embalwa kunohlobo olukhula kubantu abadala., futhi ingaziphatha ngendlela enolaka kancane.

Kungani la mathumba e-granulosa cell akheka? Iyini imbangela?

Lena inkinga abantu abaningi abanayo. Eqinisweni, ochwepheshe bezokwelapha abakaqondi ngokugcwele ukuthi yini ngempela ebangela lokhu . Kodwa-ke, abakutholile ukuthi abantu abaningi abanalezi zimila banoshintsho, noma ukuguquka, ku-gene ebizwa ngokuthi ``(FOXL2)``. Ngokuvamile, le gene ``(FOXL2)`` isiza amangqamuzana e-granulosa ukuba akhule kahle futhi aphile kahle. Ngakho-ke, uma kukhona ushintsho kule gene, kucatshangwa ukuthi kungaba esinye sezizathu ezenza lezi zimila zikhule.

Ziyini izimpawu ze-Granulosa Cell Tumor?

Uphawu oluyinhloko olubonakala kulokhu ukwanda kwezinga le-hormone i-estrogen emzimbeni .

• Entombazaneni encane , lokhu kugcwala kwe-estrogen kungabangela ukuthi idlule ekuthombeni kusenesikhathi . Lokhu kusho ukuthi ingase ikhule amabele ngaphambi kweminyaka evamile futhi ikhule izinwele ezindaweni eziyimfihlo.
• Abesifazane asebekhulile bavame ukuzwa izimpawu ezifana nalezi:
• Ukopha okungavamile kwesibeletho (AUB) noma ukopha ngemva kokunqamuka kokuya esikhathini kuyimpawu ebaluleke kakhulu.
• Ukuvuleka kwesisu (ukuzizwa ugcwele) .
• Ukuya esikhathini okungajwayelekile noma ukuyeka ngokuphelele ukuya esikhathini isikhathi esithile.
• Ubuhlungu bebele, ukuthamba (amabele athambile noma abuhlungu) .

Ngezinye izikhathi, lesi simila singadala ubuhlungu esiswini kuphela uma siqhuma . Kodwa lokho akwenzeki kuwo wonke umuntu.

Yiziphi izinkinga ezingaba khona ngenxa yalesi simila?

Uma lesi simila se-granulosa cell singelashwa kahle, singandisa ingozi yezinye izinkinga zempilo. Yingakho kubalulekile ukusixilonga nokuselapha ngokushesha. Ezinye zezinkinga ezinkulu ezingase zenzeke yilezi:

• I-Endometrial hyperplasia : Lokhu kungaba yisandulela somdlavuza wesibeletho.
• Umdlavuza wesibeletho .
• Umdlavuza webele .
• Ubunzima bokuthola abantwana (Ukungazali) .

Odokotela bayixilonga kanjani le `(Granulosa Cell Tumor)`?

Ngokuvamile, odokotela basebenzisa amasu ahlukahlukene okuthwebula izithombe ukuze baxilonge izimila zeseli le-granulosa. Kungadingeka ukuthi wenze izivivinyo ezinjengalezi:

• I-CT scan .
• I-MRI scan .
• I-ultrasound ye-Transvaginal : Lokhu kuvumela ama-ovari ukuthi abonakale kahle.

Ngaphezu kwalokho, udokotela wakho angase futhi acele ukuhlolwa kwegazi . Ngokukhethekile, bazofuna okuthile okubizwa ngokuthi ama-tumor markers . I-Inhibin iyi-marker ekhethekile ekhiqizwa yila ma-tumors eseli le-granulosa futhi ingatholakala egazini. Bangase futhi bacele ukuhlolwa kwegazi okuthile ukuze banqume ezinye izimo.

Ziphathwa kanjani izimila ze-granulosa cell?

Ukwelashwa kokuqala nokuyinhloko kwalokhu ukuhlinzwa . Udokotela ohlinzayo uzama ukususa isimila esiningi ngangokunokwenzeka, kuyilapho eqaphela ukuthi angonakalisi izicubu ezinempilo.

• Uma ungasafisi ukuba nezingane, noma uma usudlulile eminyakeni yokuzala, udokotela wakho angase akuncomele ukususa ama-ovari akho (i-oophorectomy) kanye nesibeletho sakho (i-hysterectomy) . Kwezinye izimo, ukususa ama-ovari kuyadingeka ukuze kususwe yonke i-GCT.

Okulandelayo, odokotela banquma ukuthi isimila sisakazeke kangakanani, noma ukuthi "isigaba" sesimila singakanani. Lena yindlela abanquma ngayo ukuthi umdlavuza usakazeke noma cha.

• Isigaba 1 se-GCT sisho ukuthi isimila asikasabalali ngaphandle kwama-ovari.
• Isigaba sesi-2 kuya kwesi-4 se-GCTs sisho ukuthi isimila sesisabalale (sakhiwe ngama-metastases) kwezinye izingxenye zomzimba.

Cabanga nje, ingxenye engcono kakhulu ukuthi kutholakala ama-GCT angu-9 kwangu-10 ngaphakathi kwesibeletho . Kulezi zinhlobo zamathumba, ukuhlinzwa kuvame ukunconywa, futhi kungaba yindlela yokwelapha kuphela.

Kodwa-ke, kuye ngobukhulu besimila kanye nezici zakho ezingabangela ukuphinda kwaso, ukwelashwa okwengeziwe kunganikezwa ukuvimbela isimila ukuthi singaphinde sivele. Udokotela wakho angase akuncome okulandelayo:

• Ukwelashwa ngamakhemikhali
• Ukwelashwa ngama-hormone
• Ukwelashwa ngemisebe

Ingabe ikhona indlela yokuvimbela ukwakheka kwalesi simila se-granulosa cell?

Ayikho indlela eqinisekile yokuvimbela lokhu ukuthi kungenzeki . Kodwa-ke, ukuphila ngendlela enempilo nokunciphisa ingozi yakho yezifo ezingamahlalakhona kungasiza ngezinga elithile. Lokho kusho ukuthi:

• Ukugcina isisindo esinempilo esifanele uhlobo lomzimba wakho, ubulili kanye nobudala.
• Gwema ngokuphelele ukubhema .
• Ukudla ukudla okunomsoco (imifino eminingi, izithelo, kanye nemifino eluhlaza).
• Ukuvivinya umzimba njalo kubalulekile empilweni yenhliziyo kanye namandla amathambo.
• Ukunciphisa ukusetshenziswa kotshwala kanye ne-caffeine .
• Ukulawula ukucindezeleka ngezinto ezifana nokuzindla kanye ne-yoga.
• Lala kahle okungenani amahora ayisikhombisa kuya kwayisishiyagalombili ubusuku ngabunye.

Unganciphisa kanjani ingozi yezinkinga ezivela ku-`(Granulosa Cell Tumor)`?

Into ebaluleke kakhulu ukubona udokotela ngokushesha uma unezimpawu ezingase zihlobane ne-`(GCT)` . Ikakhulukazi, uma unesifo sokopha okungajwayelekile, ubuhlungu bebele, ukuqaqamba, noma ukopha ngemva kokunqamuka kokuya esikhathini, kufanele nakanjani ufune iseluleko sezokwelapha . `(GCT)` ivame ukuphumelela kakhulu uma yelashwa kusenesikhathi.

Ingabe izimila ze-granulosa cell zingelapheka?

Yebo, iyelapheka . Amathuba okwelashwa aphezulu uma la mathumba esuswa kusenesikhathi , ikakhulukazi ngokuhlinzwa.

Kodwa-ke, uma udokotela eyithola, akunakwenzeka ukuthi yelaphe i-GCT uma isivele isakazekele kwezinye izingxenye zomzimba. Yingakho sihlala sithi uma unezimpawu ze-GCT, bona udokotela ngokushesha .

Yini ongayilindela ngemva kokwelashwa `(GCT)`?

Ngemva kokususwa kwesimila, kuzodingeka ubone udokotela wakho njalo iminyaka eminingana ukuze kulandelwe . Lokhu kungenxa yokuthi izimila ngezinye izikhathi zingabuya eminyakeni eminingi kamuva. Udokotela wakho uzohlola njalo ukuze abone ukuthi isimila sesibuyile yini. Lokhu kungafaka:

• Ukuhlolwa kwe-pelvic .
• Ukuhlolwa kwegazi ukuhlola izimpawu zokubuyela komdlavuza.
• Ukuhlolwa kokuskena .

Iyini inhloso yamathumba e-granulosa cell?

Umbono we-GCT uncike ekutheni isimila sithuthuke kangakanani (isigaba) lapho uxilongwa . Uma udokotela wakho ethola i-GCT ngaphambi kokuba isakazeke (isakazeke) kwezinye izingxenye zomzimba, umbono uvame ukuba muhle .

Yini enye okufanele ngiyibuze udokotela wami?

Uma ufuna ukwazi okwengeziwe ngalokhu, ungabuza udokotela wakho imibuzo efana nale:

• Yini okungenzeka kakhulu ukuthi iyimbangela yezimpawu zami?
• Yiziphi izivivinyo okufanele ngizenze ukuqinisekisa ukuthi ngine-Granulosa Cell Tumor?
• Yiziphi izindlela zokwelapha enginazo?
• Yimaphi amathuba okuthi lokhu `(GCT)` kuzophinde kuvele ngemva kokwelashwa?
• Ngibheka kanjani ngemva kokususwa kwesimila se-granulosa cell?

Izinto ezibaluleke kakhulu okudingeka uzikhumbule kulesi sihloko (Umyalezo Wokuya Ekhaya)

Kulungile, ngakho-ke, kusukela kulokho esikhulume ngakho, lezi yizinto ezibaluleke kakhulu okudingeka uzikhumbule:

• I-Granulosa cell tumor iyisimila esingavamile, esivame ukuba yisifo esingenabungozi esikhula ema-ovari .
• Ngokuvamile ngenxa yaleziAmazinga e-estrogen emzimbeni ayanda.
• Ngakho-ke, kungase kube nezimpawu ezifana nokopha kwesibeletho okungavamile, imijikelezo yokuya esikhathini engajwayelekile, kanye nokukhula kwesisu .
• Ukwelashwa okuyinhloko ukususa isimila ngokuhlinzwa .
• Into ebaluleke kakhulu ukuthi uma lokhu kutholakala kusenesikhathi, amathuba okululama aphezulu kakhulu .
• Ngakho-ke, uma unezinye zalezi zimpawu, ungesabi noma ulibale, kodwa bona udokotela ngokushesha ukuze akunike iseluleko .

Ngithemba ukuthi lolu lwazi luwusizo. Hlala uphilile!

Isimila se - Granulosa cell, umdlavuza wesibeletho, i-estrogen, impilo yabesifazane, ukopha okungavamile, izimpawu zomdlavuza, ukuhlinzwa