Ake sifunde kabanzi ngamaseli 'e-eosinophil' emzimbeni wakho.

Wake wezwa igama elithi 'Eosinophil'? Mhlawumbe udokotela ukutshele lona ngemva kokubheka imiphumela yokuhlolwa kwegazi lakho, noma mhlawumbe leli gama lisha kuwe. Kodwa-ke, lawa ma-eosinophil angamasosha abaluleke kakhulu emzimbeni wethu. Enza umsebenzi omuhle kakhulu ekugcineni imizimba yethu iphilile. Ngakho-ke, namuhla sizoxoxa ngokuningiliziwe ngalolu hlobo lweseli olubizwa ngokuthi i-eosinophil, ukuthi lwenzani, nokuthi kwenzekani uma luba phansi kakhulu.

Ubani lo eosinophil?

Kalula nje, i-eosinophil uhlobo lweseli elimhlophe egazini lethu. Njengoba wazi, amangqamuzana amhlophe egazi (ama-leukocyte) angamasosha ayinhloko esimisweni somzimba wethu sokuzivikela, uhlelo olusivikela ezifweni. Kunezinhlobo ezahlukene zala maseli amhlophe egazi. Njengoba nje kunezinhlobo ezahlukene zamabutho ebuthweni.

Kunezinhlobo ezintathu eziyinhloko zamaseli amhlophe egazi:

1. Ama-granulocyte

2. Ama-lymphocyte

3. Ama-monocyte

Umlingiswa wethu oyinhloko, i-eosinophil, ungoweqembu elibizwa ngokuthi 'ama-granulocytes'. Igama elithi 'ama-granulocytes' lisuselwa eqinisweni lokuthi la maseli anezinhlayiya ezincane ngaphakathi kwawo. Ngaphezu kwama-eosinophil, kunezinye izinhlobo ezimbili zama-granulocyte ezibizwa ngokuthi 'ama-neutrophil' kanye 'nama-basophil'. Wonke la maseli asebenza ndawonye ukulwa nezitha ezingena emizimbeni yethu.

Indima yama-eosinophil ikakhulukazi ukuvimba ukukhula kwezinto eziphilayo zakwamanye amazwe, ikakhulukazi izimuncagazi, ezicasha ngaphakathi kwamaseli ethu futhi zisigulise.

Yini eyenziwa yila maseli e-eosinophil?

Cabanga nje, lapho into engaziwa, njengegciwane noma i-allergen, ingena emizimbeni yethu, amangqamuzana ethu amhlophe egazi aqala ukusebenza ngokushesha. Njengamasosha aqeqeshwe ngokukhethekile, afuna futhi abhubhise umhlaseli ngaphambi kokuba alimaze amanye amangqamuzana ethu.

Amaseli e-Eosinophil nawo aqeqeshwe ngendlela efanayo ukuba aphume emnkantsheni wethu angene ezicutshini zethu ukuze abe onogada. Ngaphakathi kwala maseli kukhona izinhlayiya ezincane zesihlabathi esikhulume ngazo ekuqaleni. Ngaphakathi kwala ma-granule kukhona iphrotheni enobuthi . Uma kufika umhlaseli, la ma-granule akhipha leyo phrotheni enobuthi, abhubhise umhlaseli, bese eyidla.

Ama-eosinophil avikela imizimba yethu kakhulu ku:

• Ukutheleleka ngamagciwane: Isibonelo, izinto ezifana ne-strongyloidiasis, ama-pinworm.
• Ezintweni eziphilayo ezikhula ngaphakathi kwamaseli ethu: Ezinye izinhlobo zamagciwane (amagciwane angaphakathi kwamangqamuzana) zicasha ngaphakathi kwamaseli ethu futhi zibangele izifo. Ama-eosinophil nawo ayasiza ekulweni nawo.
• Lawa maseli asiza futhi ukulawula ukusabela okusheshayo kwe-hypersensitivity ( izinto ezibangela ukungezwani komzimba) okubangelwa ukuchayeka kuzinto ezibangela ukungezwani komzimba .

Atholakala kuphi amaseli amaningi e-eosinophil?

Ama-eosinophil uhlobo lwamaseli amhlophe egazi ahlala ezicutshini zomzimba wethu. Avame ukutholakala ku:

• Egazini
• Emnkantsheni wethambo
• Ezicutshini zamafutha (izindawo lapho amafutha agcinwa khona emizimbeni yethu)
• Emaphashini
• Esikhumbeni
• Esiswini

Amangqamuzana e-eosinophil abukeka kanjani?

Lawa maseli e-eosinophil mancane kakhulu, futhi angabonakala kuphela ngaphansi kwe-microscope. Ayindilinga. Ngokuvamile, emizimbeni yethu, awanombala, okusho ukuthi awanawo umbala. Kodwa uma ebhekwa ngaphansi kwe-microscope, lapho kufakwa umbala okhethekile (udayi we-acidic), umbala wala maseli uyashintsha, okwenza kube lula ukuwuhlola. Lo mbala uguqula amangqamuzana abe umbala onsomi-opinki.

Ama-eosinophil makhulu kancane kunamanye amangqamuzana. Esinye sezici zawo ezibonakala kalula yi -nucleus yawo. Ibukeka njengamaconsi amabili amanzi axhunywe ngentambo, enamacembe amabili. Uyazi, ngaphakathi kwe-nucleus yilapho kukhona khona i-DNA yeseli. Konke kumayelana nezinto ezibalulekile. Le nucleus intanta kuphrotheni efana nesihlabathi (ama-granule esikhuluma ngawo).

Mangaki ama-eosinophil akhona emzimbeni wethu?

Ama-eosinophil awuhlobo lwamaseli amhlophe egazi. Amaseli amhlophe egazi akha cishe u-1% wenani eliphelele lamaseli emizimbeni yethu. Kumaseli amhlophe egazi ajikeleza emzimbeni womuntu omdala onempilo, ama-eosinophil akha ngaphansi kuka-5% . Lokho kusho ukuthi yize eyingcosana kakhulu, insizakalo ayinikezayo ayibalulekile.

Akhiqizwa kuphi ama-eosinophil?

Lawa maseli abalulekile akhiqizwa ezicutshini ezithambile ngaphakathi kwamathambo ethu, okuthiwa umnkantsha . Ngemva kokuba evuthiwe emnkantsha, ama-eosinophil aya ezicutshini ezinamafutha zomzimba wethu, njengesisu.

Yiziphi izimo ezivamile ezithinta ama-eosinophil?

Izimo ezithinta ama-eosinophil azivamile. Kunezimo ezimbili eziyinhloko ezithinta kokubili inani lama-eosinophil aphansi kanye nenani eliphezulu.

Ukwehla kwama-eosinophil: i-Eosinopenia

I-Eosinopenia yilapho sinamaseli e-eosinophil ambalwa kunokujwayelekile emizimbeni yethu. Kunezimo eziningana ezingabangela lokhu:

• I-Cushing's syndrome: Lokhu kwenzeka lapho umzimba ukhiqiza i-hormone i-cortisol eningi kakhulu futhi awekho amangqamuzana e-eosinophil anele. I-Cortisol iyi-hormone elawula amazinga ethu kashukela egazini futhi iguqula ukudla kube amandla.
• I-Sepsis: I-Sepsis yisimo esibi kakhulu sezokwelapha esibangela ukuvuvukala kanye nokujiya kwegazi emzimbeni wonke. Ngokuvamile kuba umphumela wokutheleleka ngamagciwane, isikhunta, amagciwane, noma igciwane.

Okubalulekile: Ngezinye izikhathi, noma ngabe inani lakho le-eosinophil liphansi ngezikhathi ezithile, kungase kungabi yingozi enkulu empilweni. Lokhu kungenxa yokuthi amanye amaseli ohlelweni lwethu lokuzivikela komzimba asiza ekubuyiseleni lokhu kuntuleka kwe-eosinophil. Kodwa-ke, ukuba namazinga aphansi e-eosinophil isikhathi eside kuyingozi. Kudinga ukunakekelwa kwezokwelapha okusheshayo.

Ukwanda kwama-eosinophil: i-Eosinophilia

I-Eosinophilia yilapho sinamaseli amaningi e-eosinophil egazini lethu kunokuvamile. Udokotela uzoxilonga lesi simo ngokusekelwe lapho kutholakala khona ama-eosinophil:

• Izinkinga zesisu ezibangelwa yi-Eosinophilic (EGID): Lezi yizimo ezithinta uhlelo lwethu lokugaya ukudla. Kulokhu, iqoqo lamaseli e-eosinophil lihlangana endaweni ethintekile, okubangela ukuvuvukala. Lesi yisimo esivame kakhulu esihlotshaniswa nama-eosinophil. Lezi zimo (EGID) zingathinta amathumbu amakhulu (i-eosinophilic colitis), i-esophagus (i-eosinophilic esophagitis), isisu (i-eosinophilic gastritis), isisu kanye namathumbu amancane (i-eosinophilic gastroenteritis), kanye nesinye (i-eosinophilic cystitis).
• Izinkinga zamaphaphu ezibangelwa yi-eosinophilic: Lokhu kuhlanganisa i-asthma ye-eosinophilic, i-bronchitis, kanye ne-pneumonia. Kuyisimo esifana ne-asthma enzima, i-bronchitis, kanye ne-pneumonia. Kulesi simo, amaphaphu agcwala amangqamuzana avuvukele futhi aminyene. Lokhu kwenza kube nzima kakhulu ukuphefumula.
• Izinkinga zegazi nezicubu ezi-Eosinophilic: Lokhu kuthinta izicubu ezixhumene ngaphansi kwesikhumba sethu (i-eosinophilic fasciitis), isikhumba (i-eosinophilic pustular folliculitis), kanye namaseli egazini lethu, emithanjeni yegazi, kanye nezitho ezibalulekile njengenhliziyo nezinso (i-eosinophilic granulomatosis ene-polyangiitis, eyayaziwa ngokuthi i-Churg-Strauss syndrome). Lezi zimo zenzeka lapho ama-eosinophils amaningi kakhulu ehlasela futhi elimaza imithambo yegazi. Uma ingelashwa, lokhu kungaholela ekugelezeni kwegazi okungekuhle kuwo wonke umzimba.

Yiziphi izimpawu ezivamile zezimo ezihlobene ne-eosinophil?

Lezi zimpawu zivame ukuvela maqondana nendawo yokulimala. Nazi ezinye zezimpawu ezivamile:

• Ukukhathala, ukukhathala
• Izilonda zesikhumba, ukuqubuka
• Ama-blister agcwele ubomvu esikhumbeni
• Ubunzima bokuphefumula, ukushoda kokuphefumula
• Ubuhlungu besisu nesisu
• Ukuvuvukala

Yiziphi izimbangela ze-eosinophilia?

Kunezici eziningana ezithinta inani lama-eosinophils egazini lethu:

• Ukudakwa utshwala
• Ukungezwani komzimba
• Izinkinga zesisu
• I-leukemia (uhlobo lomdlavuza wegazi)
• Ukukhiqizwa ngokweqile kwe-hormone i-cortisol
• Ukutheleleka kwezimuncagazi

Ingabe i-eosinophilia iwumphumela wokutheleleka?

Ukwanda kwama-eosinophil (i-eosinophilia) kungaba umphumela wokutheleleka, kodwa akusiyo njalo imbangela eyinhloko . Izimuncagazi zingabangela ukwanda kwama-eosinophil. Lezi zimuncagazi zingadluliselwa kusuka kumuntu kuya komunye noma kusuka esilwaneni kuya komunye, ikakhulukazi kusuka ezinjeni kuya emakati. Udokotela wakho uzokuvivinya ukuze abone ukuthi unesifo esimuncagazi. Uma kunjalo, ukuselapha ngokuvamile kuzobuyisela amazinga akho e-eosinophil esimweni esijwayelekile.

Yiziphi izivivinyo ezivamile ezihlola impilo yamaseli akho e-eosinophil?

Ukuxilongwa kwezimo ezihlobene ne-eosinophil kuqala ngokubalwa kwegazi okuphelele (i-CBC) . Lokhu kuhilela ukuthatha isampula yegazi lakho bese ubala inani lamaseli akulo, ikakhulukazi amaseli amhlophe egazi, ukuze ubone ukuthi aphansi kakhulu noma aphezulu kakhulu. Ngaphezu kwalokho, kunezinye izivivinyo:

• Inani lama-eosinophil aphelele: Lokhu futhi ukuhlolwa kwegazi. Kufana nokubalwa kwegazi okuphelele. Kulinganisa ngqo inani lama-eosinophil kusampula yegazi lakho. Udokotela uthatha inani elincane legazi emthanjeni bese ebheka isampula ngaphansi kwe-microscope. Kufakwa idayi ukuze kwenziwe amaseli abonakale kakhudlwana, bese udokotela ebala inani lama-eosinophil kumaseli ayi-100. Inani lama-eosinophil aphelele libalwa ngokuphindaphinda lelo phesenti ngenani lamaseli akho amhlophe egazi.
• Ukuhlolwa kwe-bone marrow biopsy: Kulokhu kuhlolwa, udokotela usebenzisa inaliti ukuthatha isampula encane ye-bone marrow yakho. Bese ihlolwa ukuze kubonwe inani, ikhwalithi, kanye nendawo yamaseli emzimbeni wakho.

Ukuze athole indawo eqondile ye-eosinophilia, udokotela angenza izivivinyo ezikhethekile kakhulu:

• I-X-ray yesifuba
• Ukuhlolwa kokusebenza kwesibindi
• Ukuhlolwa kwesampula yendle
• I-biopsy yezicubu
• Ukuhlolwa komchamo

Liyini izinga elijwayelekile le-eosinophil?

Umuntu ophilile kufanele abe namaseli e-eosinophil aphakathi kuka-30 no-350 nge-microliter ngayinye yegazi. Uma kunamaseli angaphezu kuka-500 nge-microliter ngayinye yegazi, kuyinani eliphezulu. Uma kunamaseli angaphansi kuka-30, kuyinani eliphansi.

Khumbula, ukwehla kanye kuphela kwenani lama-eosinophil, noma ngabe kuyiconsi nje, kungase kungabi yingozi enkulu. Amanye amangqamuzana amhlophe egazi ohlelweni lwakho lokuzivikela komzimba ayasiza ekulungiseni ukuntuleka kwaleli gciwane.

Iyini izinga eliphezulu le-eosinophil?

Udokotela wakho uzohlukanisa ubukhulu be-eosinophilia, ngokusekelwe emiphumeleni yenani eliphelele le-eosinophil:

• Okuncane: Phakathi kwamaseli e-eosinophil angu-500 no-1,500 nge-microliter ngayinye yegazi.
• Okulingene: Phakathi kwama-eosinophil angu-1,500 no-5,000 nge-microliter ngayinye yegazi.
• Okubi kakhulu: Ama-eosinophil angaphezu kuka-5,000 nge-microliter ngayinye yegazi.

Ingabe izinga eliphezulu le-eosinophil liwuphawu lomdlavuza?

Nakuba lokhu kungavamile, amazinga aphezulu e-eosinophil angase abe uphawu lokuthi unomdlavuza . Amazinga aphezulu e-eosinophil angase ahlotshaniswe nezinhlobo eziningana zomdlavuza:

• Umdlavuza webele
• Umdlavuza we-Colorectal
• Umdlavuza wesibeletho
• I-Hodgkin lymphoma
• Umdlavuza wesibeletho
• Umdlavuza we-prostate

Uma udokotela wakho esola umdlavuza, uzokwenza ezinye izivivinyo, njenge-biopsy, ukuhlolwa kwegazi okwengeziwe, noma ukuhlolwa kwesithombe, ukuze kutholakale lesi sifo futhi kuqalwe ukwelashwa.

Yiziphi izindlela zokwelapha ezivamile zamazinga aphezulu e-eosinophil?

Ukwelashwa kwezimo ezinamazinga aphezulu e-eosinophil kuyahlukahluka kuye ngendawo kanye nobunzima besifo. Ukwelashwa kokunciphisa amazinga aphezulu e-eosinophil kufaka phakathi:

• Uma une-esophagitis, gwema ukudla okuthile (ukudla okunamafutha, okunongwe, okune-asidi).
• Uma usabela kabi emuthini othile, yeka ukuthatha umuthi noma ushintshe umthamo.
• Ukuthatha imithi yokulwa nokuvuvukala.

Izimo ezinamazinga aphezulu kakhulu e-eosinophil zihlala isikhathi eside , okusho ukuthi zidinga ukwelashwa nokuphathwa kwesikhathi eside.

Yiziphi izindlela zokwelapha ezivamile zamazinga aphansi e-eosinophil?

Ukwelashwa kwezimo ezinamazinga aphansi e-eosinophil kufaka phakathi:

• Ukuthatha ama-corticosteroids.
• Ukunciphisa ukusetshenziswa kotshwala.

Esikhathini esiningi, umzimba wakho uzobona ukuntuleka kwama-eosinophil kanti lonke uhlelo lwakho lokuzivikela komzimba luzosiza ekulungiseni ukuntuleka kwawo. Kodwa-ke, uma amazinga akho e-eosinophil engabuyeli esimweni esijwayelekile ngenxa yesimo sempilo esicashile, ukwelashwa kwesikhathi eside kungadingeka.

Ngingawagcina kanjani amaseli ami e-eosinophil ephilile?

Nazi ezinye izinto ongazenza ukuze ugcine amaseli akho e-eosinophil ephilile:

• Gwema izinto ezibangela ukungezwani komzimba.
• Yidla ukudla okunomsoco. Pheka ukudla kahle bese ukufudumeza kuze kufike ezingeni lokushisa elifanele langaphakathi ngaphambi kokudla.
• Nciphisa ukusetshenziswa kotshwala.
• Landela imikhuba efanele yokuhlanzeka, njengokugeza izandla zakho njalo.

Ayini ama-Acidophil?

Ama-Acidophil elinye igama, kodwa elingajwayelekile, lama-eosinophil. Igama elithi "acidophilic" livela egameni elithi "acidophilic," elisho "ukuthanda i-asidi." Leli gama livela endleleni ama-granules kumaseli e-eosinophil ashintsha ngayo umbala ngaphansi kwe-microscope lapho egcotshwe ngedayi ye-acidic stain. Le dayi iguqula amaseli abe pinki noma onsomi, okwenza kube lula ukuwabona.

Ngakho-ke, ama-eosinophil ayingxenye ebaluleke kakhulu yesimiso sethu somzimba sokuzivikela. Adlala indima enkulu ekuvikeleni imizimba yethu kubahlaseli bakwamanye amazwe. Uma udokotela wakho esola ukuthi amazinga akho e-eosinophil angaphezulu kwesilinganiso esijwayelekile, uzokwenza ukuhlolwa kwegazi ukuhlola impilo yamaseli akho. Esikhathini esiningi, amazinga aphansi e-eosinophil awayona into enkulu, ngoba amanye amaseli asiza ukuvala isikhala sokuntuleka futhi agcine umzimba wakho usebenza.

Masikhumbule izinto ezibaluleke kakhulu (Umyalezo Wokuya Ekhaya)

Kulungile, ake sifingqe izinto ezibaluleke kakhulu okudingeka uzikhumbule kulokho esikhulume ngakho.

• Ama-eosinophil awuhlobo lwamaseli amhlophe egazi. Ayingxenye yesimiso sethu somzimba sokuzivikela.
• Ngokuyinhloko zilwa nokutheleleka yizinambuzane, izinto eziphilayo ezikhula ngaphakathi kwamaseli, kanye nokusabela kokungezwani komzimba .
• Ukwehla kwenani lama-eosinophil (i-eosinopenia) noma ukwanda kwenani lama-eosinophil (i-eosinophilia) kungabangelwa izimo zezokwelapha ezahlukahlukene.
• Ukuhlolwa kwegazi kungenziwa ukuze kutholakale amazinga e-eosinophil yakho.
• Ngokuvamile, umuntu ophilile unamaseli e-eosinophil aphakathi kuka-30 no-350 nge-microliter ngayinye yegazi.
• Uma ubona ushintsho emazingeni akho e-eosinophil, kungcono ungesabi bese ubona udokotela ukuze akunike iseluleko.

Ngithemba ukuthi uyaqonda kahle ama-eosinophil. Ukuqaphela izinto ezinjengalezi kusiza kakhulu ekunakekeleni impilo yethu.

I- Eosinophil, amangqamuzana amhlophe egazi, amasosha omzimba, ukungezwani komzimba, ukutheleleka ngamagciwane, i-eosinophilia, i-eosinopenia, ukuhlolwa kwegazi