Ingabe udokotela wakho wakubhalela umuthi omusha? Ingabe bathi ubizwa ngokuthi i-alpha-blocker? Mhlawumbe kwakungenxa yomfutho wegazi lakho, noma uma uyindoda, ngenxa yesimo esifana nokukhula kwe-prostate. Ungakhathazeki, igama lingase lizwakale liyinkimbinkimbi kancane. Namuhla, sizoxoxa ngalolu hlobo lomuthi ngamagama alula, ukuthi lusebenza kanjani, nokuthi yini okudingeka ukwazi.
Kalula nje, ziyini lezi zithiyo ze-alpha blocker?
Ama-Alpha-blocker uhlobo lomuthi osetshenziswa kakhulu ukwelapha umfutho wegazi ophakeme , noma umfutho wegazi ophakeme. Asetshenziswa futhi nakwezinye izimo eziningana.
Cabanga ukuthi kukhona "ama-receptor" amancane emaseli omzimba wethu. Kufana nokukhiya emnyango. Uma ufaka ukhiye, ungawuvula umnyango. Uma ama-hormone athile ebopha kula ma-receptor, kwenzeka izenzo ezithile. Lo muthi okwenziwayo ukuvimba okwesikhashana ama-receptor "alpha". Kufana nokufaka okuthile kukhiye nokuvimbela ukhiye ukuthi ungafakwa. Lokhu kuvimbela izenzo ezithile ukuthi zenzeke.
Hlola ukuthi noma yimiphi imithi udokotela wakho ayinikezile ifaka amagama afana ne-doxazosin, i-prazosin, noma i-terazosin. Lezi yizinhlobo ezivame kakhulu zokuvimbela i-alpha.
Izinhlobo zama-Alpha-Receptors emzimbeni wethu
Kunezinhlobo ezimbili eziyinhloko zama-alpha receptors emzimbeni wethu. Kuhle ukwazi okuncane ngalokhu ukuze uqonde ukuthi lo muthi usebenza kanjani.
| Uhlobo lomamukeli | Umsebenzi owenziwayo |
|---|---|
| I-Alpha-1 receptor | Lokhu kutholakala kakhulu emithanjeni yethu yegazi, emisipha ye-prostate, kanye nesinye. Uma lokhu kusebenza, imithambo yegazi iyafinyela. Bese ingcindezi iyanda. Imisipha ye-prostate nayo iyaqina. |
| I-Alpha-2 receptor | Lokhu kutholakala kakhulu ebuchosheni nasohlelweni lwezinzwa. Kusiza ekulawuleni ukusebenza kohlelo lwezinzwa nokugcina umzimba uzolile. |
Uma imithi ye-alpha-blocker ivimba ama-receptor e-alpha-1, imithambo yegazi kanye nemisipha e-prostate gland kuyakhululeka . Uma imithambo yegazi ikhululeka, igazi lingageleza kalula, okwehlisa umfutho wegazi. Uma imisipha e-prostate gland ikhululeka, kwenza kube lula ukuchama.
Yiziphi izinhlobo ze-Alpha-Blockers?
Le mithi ingahlukaniswa ngezinhlobo ezimbili eziyinhloko.
1. Ama-Alpha-blocker akhethiwe
Lokhu kufana nesibhamu esidubulayo. Kushaya umgomo ngqo kuphela. Lokho kusho ukuthi lolu hlobo lomuthi luhlasela kakhulu ama-receptor e-alpha-1 . Ngakho-ke, imiphumela emibi mincane kakhulu. Ezinye izibonelo yilezi:
- I-Alfuzosin
- I-Doxazosin
- I-Prazosin
- I-Silodosin
- I-Tamsulosin
- I-Terazosin
2. Ama-Alpha-Blockers angakhethi
Lezi zihlukile kancane. Zifana nesibhamu esidubulayo. Zivimba ama-receptor e-alpha-1 kanye ne-alpha-2. Lokhu kusho ukuthi zinomthelela omkhulu emzimbeni, futhi zinemiphumela emibi eminingi . Ngoba zivimba nama-receptor e-alpha-2, inani le-norepinephrine, i-hormone yokucindezeleka emzimbeni wethu, liyakhula, okungakhuphula izinga lokushaya kwenhliziyo futhi kubangele ukungaphumuli. I-Phenoxybenzamine kanye ne-phentolamine ziyizibonelo zalolu hlobo.
Ingabe lo muthi unikezwa kuphela ngenxa yomfutho wegazi nezinkinga ze-prostate?
Cha. Lo muthi uwusizo nakwezinye izimo eziningana zezokwelapha.
- I-Benign Prostatic Hyperplasia (BPH): Lesi yisimo lapho indlala ye-prostate ivuvukala khona njengoba amadoda ekhula. Lokhu kwenza kube nzima ukuchama. Ama-Alpha-blockers aphumuza imisipha yendlala ye-prostate, avumela umchamo ukuthi ugeleze kalula.
- Izinhlobo ezithile zezimila: Lawula izimila ezikhiqiza ama-hormone amaningi njenge-adrenaline.
- Isifo Sokucindezeleka Ngemva Kwenhlekelele (PTSD): Lawula ukucindezeleka, ikakhulukazi amaphupho amabi, okwenzeka ngemva kwezehlakalo ezimbi kakhulu.
- Isenzakalo sikaRaynaud: Isimo lapho iminwe nezinzwane ziphenduka zibe mhlophe, zibe luhlaza okwesibhakabhaka, futhi zibe ndikindiki lapho zibekwe emakhazeni. Lo muthi usiza ekuphumuzeni imithambo yegazi.
- Amatshe Ezinso: Siza amatshe amancane anamathele ku-ureter, ipayipi elithwala umchamo lisuka ezinso liye esinyeni, ukuthi adlule kalula.
- I-Prostatitis: Ukuvuvukala kwendlala ye-prostate.
Ngidinga ukuthatha lo muthi isikhathi esingakanani?
Kuya ngesimo sezokwelapha onikwa sona lo muthi. Ezimweni ezifana nomfutho wegazi ophakeme noma i-BPH, kungadingeka ukuthi uthathe lo muthi isikhathi eside . Enkingeni yesikhashana efana namatshe ezinso, kungadingeka ukuthi uwuthathe isikhathi esifushane.Ithi kufanele kusetshenziswe kuphela.
Okubaluleke kakhulu: Ungayeki ukuthatha lo muthi ngokuzumayo ngaphandle kokubonisana nodokotela wakho nganoma yisiphi isizathu . Ukwenza kanjalo kungabangela izinkinga ezinkulu. Kungabangela ngisho nomfutho wegazi lakho ukuba ukhuphuke ngokuzumayo ufike ezingeni eliyingozi.
Uma ulawula umfutho wegazi lakho ngokwenza izinguquko endleleni yokuphila (ukuzivocavoca umzimba, ukudla okunempilo), noma uma uhlinzwa ukuze kususwe indlala yakho ye-prostate, udokotela wakho angakutshela ukuthi uyeke ukuthatha lo muthi. Konke lokhu kufanele kwenziwe kuphela ngaphansi kweseluleko sikadokotela.
Ake sifunde nangemiphumela emibi kanye nezingozi.
Njenganoma yimuphi umuthi, ama-alpha-blockers angaba nemiphumela emibi, kodwa akuwona wonke umuntu oyitholayo.
Imiphumela emibi evame kakhulu (ikakhulukazi ekhethiwe):
- Isiyezi kanye nokulahlekelwa yikhanda: Umfutho wegazi ophansi (i-orthostatic hypotension) ungabangela ukubona okufiphele, ikakhulukazi uma umi ngokuzumayo uhleli.
- Umphumela womthamo wokuqala: Lo muzwa wokungaphatheki kahle kanye nokwehla komfutho wegazi kungase kubonakale kakhulu ezinsukwini zokuqala ezimbalwa ngemva kokuqala umuthi.
- Ikhanda elibuhlungu
- Ukukhathala
- Ukuzicabangela: Lesi yisimo esibucayi nesiphuthumayo. Kuwukuvuka okubuhlungu kwepenisi isikhathi esingaphezu kwamahora amane. Uma lokhu kwenzeka, kufanele uye ekamelweni lezimo eziphuthumayo (ETU) esibhedlela ngokushesha.
Uma uthatha imithi engakhethi, ungase uzwe nokushaya kwenhliziyo okukhuphukile kanye nokuthuthumela kwemisipha.
Lo muthi ungase uhlangane notshwala, amanye amajusi e-citrus, kanye neminye imithi. Ngakho-ke tshela udokotela wakho ngayo yonke eminye imithi oyiphuzayo.
Ubani okungafanele athathe lo muthi?
Ama-alpha-blocker awafanele abantu abanezimo ezithile zempilo.
- Uma uhlela ukuhlinzwa kwe-cataract: Lo muthi ungase uthinte i-pupil, okungenza ukuhlinzwa kube nzima. Ngakho-ke qiniseka ukuthi wazisa udokotela wakho wamehlo ngalokhu.
- Omama abancelisayo: Imithi engakhethi ayifaneleki kakhulu.
- Uma unomlando we-Orthostatic Hypotension: Lokhu kusho ukuthi uvame ukuzizwa unesizungu lapho usukuma uhleli, lo muthi ungenza isimo sibe sibi kakhulu.
- Uma uthatha imithi yokungasebenzi kahle kwenduku: Eminye imithi ingasabela kulokhu futhi ibangele umfutho wegazi ophansi ngendlela eyingozi.
- Uma unesifo sezinso noma isifo sesimiso sokujikeleza kwegazi:Imithi engakhethi ingase ingafaneleki.
Yini engenziwa ukunciphisa imiphumela emibi uma umuthi usuqaliwe?
Yebo. Kuneseluleko esisodwa esibalulekile. Uma udokotela wakho ekutshela ukuthi uqale i-alpha-1-blocker ekhethiwe, thatha iphilisi lokuqala ebusuku ngaphambi kokulala.
Ngoba "umphumela womthamo wokuqala" yisikhathi sokuqala uqala ukuzwa imiphumela yomthamo wokuqala. Uma uthatha umuthi ngaphambi kokulala ebusuku, izinto ezifana nokwehla komfutho wegazi kanye nesiyezi zizokwenzeka ngenkathi ulele, ngakho ngeke uzizwe kakhulu. Lesi iseluleko esibaluleke kakhulu.
Kufanele ubonane nini nodokotela?
Uma izimpawu zakho zishintsha ngokuzumayo, ikakhulukazi uma zikwenza kube nzima ngawe ukwenza imisebenzi yakho yansuku zonke, shayela udokotela wakho. Kodwa-ke, kufanele ufune usizo lwezokwelapha ngokushesha uma kwenzeka noma yikuphi kwalokhu okulandelayo:
| Izimo ezidinga ukwelashwa okuphuthumayo | |
|---|---|
| Ukulahlekelwa ukwazi noma ukuquleka | Ukuquleka noma ukuquleka |
| Ubuhlungu besifuba (i-angina) | Ubuhlungu besifuba |
| Ubunzima bokuphefumula | Ukuphelelwa umoya |
| Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile | Ukushaya kwenhliziyo okusheshayo noma okungajwayelekile |
| I-Priapism (ukuma okubuhlungu okuhlala isikhathi esingaphezu kwamahora amane) | Ukulala okubuhlungu, okuthatha amahora amane |
| Izimpawu zokungezwani komzimba okukhulu (i-anaphylaxis) - isib. amaqhubu, ukulunywa, ukuvuvukala, ubunzima bokugwinya. | Izimpawu zokusabela okukhulu kokungezwani komzimba |
Kuvamile ukuzizwa ukhathazekile noma ukhathazekile kancane lapho uqala umuthi omusha. Ama-Alpha-blockers ayiqembu lemithi elisetshenziswa kabanzi elisebenza kahle ekwelapheni izimo eziningi. Uma udokotela wakho ekunike lo muthi, xoxa nganoma yiziphi izinkinga noma imibuzo onayo nodokotela wakho. Lokhu kuzokusiza ukuthi uqonde kahle ukuthi uwusebenzisa kanjani umuthi.
Umlayezo Wokuya Nawe Ekhaya
- Ama-Alpha-blocker uhlobo lomuthi olapha kakhulu umfutho wegazi ophakeme kanye ne-prostate ekhuphukile emadodeni.
- Ungalokothi uyeke ukuthatha lo muthi ngokuzumayo ngaphandle kweseluleko sikadokotela. Kungaba yingozi.
- Uma uqala umuthi, ukuthatha umthamo wokuqala ngaphambi kokulala kunganciphisa imiphumela emibi efana nokuzumeka kanye nokozela.
- Uma uzwa izimpawu ezinzima njengobuhlungu besifuba, ukulahlekelwa ukwazi, noma ukuphefumula okubuhlungu okuhlala isikhathi esingaphezu kwamahora amane, hamba uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela ngokushesha.
- Kubaluleke kakhulu ukwazisa udokotela wakho nganoma yimiphi eminye imithi, amavithamini, noma izithasiselo ozithathayo.
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