Ingabe ubulokhu uhlushwa yisifo samalunga noma isimo samathumbu esivuvukalayo isikhathi eside? Uke wazibona izimpawu ezintsha ezifana nemilenze evuvukele noma umchamo onegwebu? Lokhu kungaba yisimo esisha esihlobene nesimo sakho esidala. Namuhla sikhuluma ngesinye isimo esingavamile kodwa esibalulekile okufanele usiqaphele. I-AA Amyloidosis.
Kuyini i-AA Amyloidosis?
Kalula nje, lesi yisifo esingavamile esithinta amaprotheni emzimbeni wethu. Singenye yezinhlobo ze-amyloidosis, iqembu elikhulu lezifo.
Cabanga ngamaprotheni emizimbeni yethu njengezingubo ezigoqwe kahle. Anesimo esithile kanye nomsebenzi othize. Kodwa kulesi sifo, isakhiwo se-3D samanye amaprotheni siyaphazamiseka, bese ephithana futhi ephithana njengamabhola entambo. Kufana nengubo ephithizelisiwe yaba yimfucumfucu futhi ilahlwe eceleni. Lawa maqoqo amaprotheni angahlelekile, esiwabiza ngokuthi ama-amyloid deposits , aqala ukuqongelela ezithweni zethu, ikakhulukazi ezindaweni ezifana nezinso nesibindi.
Lokhu kubizwa nangokuthi 'i-amyloidosis yesibili'. Isizathu salokhu ukuthi akusona isifo esizenzekela sodwa. Kwenzeka njengomphumela omubi kakhulu noma inkinga yesinye isifo sokuvuvukala isikhathi eside emzimbeni. Uma kukhona ukuvuvukala emzimbeni wethu isikhathi eside, izinga leprotheni ebizwa ngokuthi 'i-serum A protein' liyakhuphuka egazini. Leli zinga eliphakeme yilona elibangela i-AA amyloidosis.
Lesi simo sithinta kanjani umzimba wami?
I-AA amyloidosis ingalimaza izitho ezibalulekile eziningana emzimbeni wakho.
- Izinso: Izinso yizona ezilimala kakhulu futhi ezivame kakhulu yilesi sifo.
- Isibindi
- Ubende
- Isisu namathumbu
- Inhliziyo: Inhliziyo ayithinteki kakhulu.
Ngaphezu kokulimaza lezi zitho zomzimba, lesi simo singabangela ukwanda kwamaprotheni emchameni wakho kanye noshintsho emazingeni e-cholesterol egazini.
Lesi sifo singabulala uma singelashwa. Ingxenye engcono kakhulu ukuthi uma isifo esibangela lesi sifo selashwa, isimo se-AA amyloidosis singalawulwa.
Yini ebangela i-AA amyloidosis?
Njengoba sixoxile ngaphambili, isizathu esiyinhloko salokhu ukuvuvukala okungapheli isikhathi eside emzimbeni. Ukuphendula lokhu kuvuvukala, isibindi sethu sikhiqiza iphrotheni ekhethekile ebizwa ngokuthi 'iphrotheni ye-serum A'. Ngokuvamile, le phrotheni iyasetshenziswa futhi isuswe. Kodwa-ke, uma kukhona ukuvuvukala okuqhubekayo, la maprotheni ayanda kakhulu, ashintshe isimo sawo, futhi, njengoba kushiwo ngaphambili, aqale ukuhlangana futhi afakwe ezithweni zomzimba.
Kunezimo eziningana zezokwelapha ezingabangela ukuvuvukala kwesikhathi eside ngale ndlela.
| Isigaba sesifo | Izibonelo |
|---|---|
| Izifo Ezingapheli | Ukutheleleka kwamagciwane isikhathi eside njengezilonda ezingapholi isikhathi eside, isifo sofuba. |
| Izifo Ze-Rheumatic | Isifo Samathambo Esibangelwa Yi-Rheumatoid Arthritis, i-Ankylosing Spondylitis. |
| Izifo Zamathumbu Ezivuvukalayo | Isifo sikaCrohn, i-Ulcerative Colitis. |
| Ezinye izinhlobo zomdlavuza | Ezinye izinhlobo zomdlavuza ohlobene negazi. |
| Izimo Ezizuzwe Njengefa | Izimo ezizuzwe njengefa ezibangela umkhuhlane ngezikhathi ezithile, njenge-Familial Mediterranean Fever. |
Ziyini izimpawu zalesi sifo?
Izimpawu zalesi sifo zivame ukuxhomeka esithweni esithintekile. Njengoba izinso zivame ukuthinteka, izimpawu ezihlobene naso zivame kakhulu.
| Isibonakaliso | Incazelo elula |
|---|---|
| Ukuvuvukala kwemilenze noma amaqakala | Lokhu okulandelayo kungenzeka ngenxa yokuqongelela koketshezi emzimbeni ngenxa yokusebenza kwezinso okungasebenzi kahle. |
| Umchamo onegwebu noma onamagwebu | Umchamo ungase ube namagwebu njengensipho njengoba izinso zikhipha amaprotheni. Lokhu kuyimpawu ebaluleke kakhulu . |
| Ukukhishwa komchamo okuncane kunokujwayelekile | Kungaba uphawu lwesifo sezinso esingamahlalakhona. |
| Uhudo olungapheli | Ama-Amyloid deposits emathunjini angaphazamisa ukumuncwa kokudla. |
| Isibindi noma izinso ezikhulisiwe | Lokhu kungatholakala ngesikhathi sokuhlolwa kwezokwelapha. |
| Umfutho wegazi ophansi | Kungase kube nesiyezi, ikakhulukazi uma umile. |
| Isicanucanu nokuhlanza | Lokhu kungenzeka uma uhlelo lokugaya ukudla luthintekile. |
Udokotela ukuthola kanjani lokhu?
Uma udokotela wakho esola lesi sifo ngokusekelwe ezimpawini zakho, indlela eyinhloko yokuqinisekisa ukuthi sikhona ukwenza i-biopsy. Lokhu kusho ukuthatha ingxenye encane yezicubu bese uyihlola ngaphansi kwe-microscope.
I-biopsy yamafutha esiswini
Lokhu ukuhlolwa okulula kakhulu. Kuthathwa ingxenye encane kakhulu yongqimba lwamafutha ngaphansi kwesikhumba sesisu sakho futhi ihlolwe. Ezimweni eziningi, lokhu kuhlolwa kungahlonza isifo.
Ukuhlolwa kwesitho somzimba
Ngezinye izikhathi, kuyadingeka ukuthatha ingxenye encane yezicubu esithweni okusolwa ukuthi sonakele (isibonelo, inso) bese uyihlola.
Kanye nalezi zivivinyo, odokotela bahlola nezinye izinhlobo ze-amyloidosis, njenge-AL amyloidosis, enezimpawu ezifanayo kodwa ezibucayi kancane.
Yiziphi izindlela zokwelapha lokhu?
Into ebaluleke kakhulu kulokhu ukwelapha isifo esiyisisekelo esibangele i-AA amyloidosis, kunokuba siselaphe ngqo.
Ake sithi unesifo samathambo esibizwa ngokuthi i-rheumatoid arthritis. Odokotela bazokunikeza imithi yokulawula isifo sakho samathambo esibizwa ngokuthi i-rheumatoid arthritis ngangokunokwenzeka. Khona-ke ukuvuvukala emzimbeni kuzoncipha. Lapho ukuvuvukala kuncipha, ukukhiqizwa kwaleyo 'protein ye-serum A' eyinkinga nakho kuzoncipha. Khona-ke ama-amyloid deposits amasha azoyeka, futhi izimpawu zizoqala ukuncipha kancane kancane.
Lokho kusho ukuthi ukwelapha isifo esiyisisekelo kuyindlela eyinhloko yokwelapha i-AA amyloidosis.
Ngaphezu kwalokho, ucwaningo luyaqhubeka ngemithi emisha engasusa ama-amyloid deposits asevele akhekile.
Ingabe lesi sifo singalapheka ngokuphelele?
Yebo, lesi sifo singalawulwa futhi siguqulwe. Kodwa kuncike ngokuphelele ekutheni isifo sokuvuvukala esisibangele silawulwa kahle kangakanani.
Into ebaluleke kakhulu ukuxilonga lesi sifo ngokushesha okukhulu bese uqala ukwelapha imbangela eyinhloko. Lokhu kuzosiza ukulawula umonakalo ezithweni zomzimba nokuvimbela umonakalo owengeziwe.
Ngizinakekela kanjani?
Uma une-AA amyloidosis, into engcono kakhulu ongayenza ukusebenzisana nodokotela wakho ukuze uthole ukwelashwa kwesifo esiyisisekelo.
- Buza udokotela wakho ngokucophelela ukuze uthole ukuthi ukugula kwakho kokuqala kuthinte kanjani lokhu, ukuthi yiluphi ukwelashwa olunikezwayo ngakho, nokuthi ungalulandela kanjani ngqo lolo hlobo lokwelashwa.
- Ngaphezu kokugula kwakho okudalaUma uba nezimpawu ezintsha (njengemilenze evuvukele, umchamo onegwebu), ungazinaki njengokungathi ziyinto encane. Tshela udokotela wakho ngazo ngokushesha.
I-AA amyloidosis iyinkinga engavamile kodwa engathi sína yesifo esivamile. Ngenhlanhla, ingalawulwa ngokwelapha isifo esiyisisekelo. Ngakho-ke, qaphela noma yiziphi izinguquko emzimbeni wakho. Khuluma nodokotela wakho nganoma yiziphi izimpawu ezintsha. Uzokwazi ukukunikeza isiqondiso osidingayo.
Umlayezo Wokuya Nawe Ekhaya
- I-AA Amyloidosis akuyona isifo esizenzekela sodwa. Kuyinkinga yesinye isifo sokuvuvukala esingamahlalakhona, njenge-rheumatoid arthritis.
- Lokhu kubangelwa amaprotheni emzimbeni ahlangana ngokungajwayelekile futhi ahlala ikakhulukazi ezithweni ezifana nezinso.
- Uma unesifo esingamahlalakhona, ungazinaki izimpawu ezifana nokuvuvukala kwemilenze kanye nokugcwala kwamagwebu emchameni wakho.
- Ukwelashwa okuyinhloko kwalokhu ukulawula isifo esiyisisekelo esibangele lokhu .
- Ukutholwa kusenesikhathi kanye nokwelashwa okuqhubekayo kwesimo esiyisisekelo kungaholela emiphumeleni emihle kakhulu. Khuluma nodokotela wakho nganoma yiziphi izimpawu ezintsha.
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho