Ingabe ngezinye izikhathi uzizwa ukhathele ngendlela engajwayelekile, ukhuluphala ngaphandle kwesizathu, noma uzizwa ukhathazekile kakhulu futhi ucindezelekile? Nakuba sivame ukucabanga ukuthi lezi yizinto ezivamile, izinto ezenzeka ngenxa yezinkinga zansuku zonke, kungase kube nezinguquko ezithile 'ku-hormone yokucindezeleka' ebizwa ngokuthi i-cortisol emzimbeni wethu ngemuva kwalokhu. Ngakho-ke uma udokotela wakho ebona lezi zimpawu, angase asikisele ukwenza lokhu kuhlolwa kwe-cortisol. Namuhla, sizoxoxa ngokuthi lokhu kuhlolwa kwe-cortisol kuyini, kungani kwenziwa, nokuthi kungakutshelani.
Okokuqala, iyini i-cortisol?
Kalula nje, i-cortisol iyi-hormone ebalulekile emzimbeni wethu. Ikhiqizwa yizindlala ezimbili ezincane ezitholakala ngaphezu kwezinso zethu, izindlala ze-adrenal. Sonke siyazi lokhu ngokuthi 'i-hormone yokucindezeleka'. Cabanga nje, lapho sibhekene nengozi engazelelwe, ingcindezi, noma ukwesaba, yi-hormone ye-cortisol enikeza imizimba yethu amandla nokulungiselela okudingekayo ukuze ibhekane nayo.
Kodwa umsebenzi we-cortisol awupheli lapho. Ineminye imisebenzi eminingi ebalulekile.
- Ukulawula umfutho wegazi.
- Kusiza ukugcina amazinga kashukela egazini.
- I-metabolism yomzimba wethu, okuyinqubo lapho ukudla esikudlayo kuhlukaniswa khona kube ama-carbohydrate, amaprotheni, namafutha bese kuguqulwa kube amandla, kuyasiza.
- Ukulawula ukuvuvukala emzimbeni.
- Ukulawula umjikelezo wethu wokulala nokuvuka.
Uyabona? I-Cortisol akuyona nje into ehlobene nokucindezeleka, iyinto ebalulekile ezintweni eziningi emizimbeni yethu ukuze isebenze kahle.
Ziyini izimpawu zamazinga aphezulu e-cortisol?
Uma amazinga akho e-cortisol ephezulu kakhulu, kungaba uphawu lwesimo esibizwa ngokuthi i-Cushing's syndrome . Nazi ezinye zezimpawu ongase uzibone.
| Isibonakaliso | Incazelo |
|---|---|
| Ukwanda kwesisindo ngokuzumayo | Ukuqongelela kwamafutha, ikakhulukazi esiswini, esifubeni, nasebusweni. |
| Ubuso obuyindilinga | Ubuso buyavuvukala futhi bube yindilinga. |
| Iqhubu lamafutha ngemuva kwentamo | Iqhubu elinamafutha lakhiwa ukuqongelela kwamafutha phakathi kwamahlombe ngemuva kwentamo. |
| Izinguquko zesikhumba | Ukuncipha kwesikhumba, ukuphuka kalula, kanye nokubonakala kwamabala okwelula anombala onsomi ezindaweni ezifana nesisu namathanga. |
| Umfutho wegazi ophezulu kanye nesifo sikashukela | Ukwanda komfutho wegazi kanye namazinga kashukela egazini. |
| Ezinye izici | Ubuthakathaka bemisipha, ubuthakathaka bamathambo, ukucindezeleka, ukukhathazeka, kanye nokujikeleza kokuya esikhathini okungajwayelekile kwabesifazane. |
Yiziphi izimbangela zokwanda kwe-cortisol?
- Imithi ye-steroid: Ukuthatha imithamo emikhulu yemithi ye-steroid njenge-dexamethasone noma i-prednisolone isikhathi eside kwezinye izimo (isib. i-asthma, i-rheumatoid arthritis).
- Isimila se-pituitary gland: Isimila esise-pituitary gland, esitholakala phansi kobuchopho bethu futhi sifana ne-master gland elawula ezinye izindlala zama-hormone emzimbeni.
- Isimila se-adrenal gland: Isimila noma ukukhula okungavamile kwendlala ngokwayo, okukhiqiza i-cortisol.
Kwenzekani uma amazinga e-cortisol ehla?
Uma amazinga e-cortisol ehla ngendlela eyingozi, kungaba uphawu lwesimo esibizwa ngokuthi isifo sika-Addison . Nazi izimpawu.
- Ukukhathala okuqhubekayo
- Isiyezi
- Ukwehlisa isisindo
- Umfutho wegazi ophansi
- Ukushintsha kombala wesikhumba onsundu noma omnyama ezindaweni ezithile
Yiziphi izimbangela ze-cortisol ephansi?
- Isifo sika-Addison: Lokhu kwenzeka lapho amasosha omzimba wethu ehlasela futhi ebhubhisa izindlala zethu ze-adrenal ngaphandle kwesizathu.
- Ukulimala kwendlala ye-adrenal: Ukulimala kwalezi zindlala ngenxa yokutheleleka noma ezinye izimbangela.
- Ukungasebenzi kahle kwendlala ye-pituitary: Uma 'i-master' ingasebenzi kahle, izindlala ze-adrenal azitholi isignali yokukhiqiza i-cortisol.
- Ukuyeka ama-steroid ngokuzumayo: Lokhu kubaluleke kakhulu. Uma usuthathe ama-steroids isikhathi eside ngenxa yesimo sezokwelapha, ukuwayeka ngokuzumayo kungabangela amazinga akho e-cortisol ehle kakhulu. Yeka njalo ukuthatha imithi ngaphansi kwesiqondiso sikadokotela wakho, unciphise kancane kancane umthamo.
Yiziphi izinhlobo zokuhlolwa kwe-cortisol ezikhona?
Uma udokotela wakho eyalela ukuhlolwa kokuhlola amazinga akho e-cortisol, kunezindlela ezintathu eziyinhloko zokwenza lokho.
1. Ukuhlolwa Kwegazi: Lena yindlela evame kakhulu. Njengoba amazinga e-cortisol ehluka phakathi nosuku (aphezulu ekuseni, aphansi kakhulu ebusuku), udokotela wakho angase akucele ukuthi uthathe amasampula egazi amabili, ngokuvamile elilodwa cishe ngo-8 ekuseni kanti elinye cishe ngo-4 ntambama. Lokhu kuzokusiza ubone ukuthi amazinga akho e-cortisol anjani ngalezo zikhathi.
2. Ukuhlolwa Kwamathe: Lokhu kuvame ukwenziwa ebusuku ngaphambi kokulala, phakathi kuka-11 no-12 phakathi kwamabili. Lokhu kungenxa yokuthi amazinga e-cortisol omuntu ophilile kufanele abe sezingeni eliphansi kakhulu ngaleso sikhathi. Uma amazinga e-cortisol esephezulu ngaleso sikhathi, kuyisizathu esihle sokusola isimo esifana ne-Cushing's syndrome. Udokotela wakho uzokunikeza ikhithi ekhethekile yalokhu.
3. Ukuhlolwa Komchamo: Ngezinye izikhathi udokotela wakho angakucela ukuthi uqoqe wonke umchamo wakho esikhathini samahora angama-24 bese uwuhlola. Lokhu kubizwa ngokuthi "ukuhlolwa komchamo kwamahora angama-24." Nakuba kungaba yinkinga encane, le ndlela ikunikeza umbono omuhle kakhulu wenani "le-cortisol yamahhala" elikhiqizwa umzimba wakho usuku lonke.
Ukuhumusha umphumela wokuhlolwa kwe-cortisol kufanele kwenziwe njalo kanye nodokotela wakho. Ungasekeli izinqumo zakho kulwazi olutholakala ku-inthanethi kuphela.
Ezinye izivivinyo ezikhethekile ezenziwe ngalolu vivinyo
Ngezinye izikhathi, ukuze uthole imbangela eqondile yamazinga aphansi noma aphezulu e-cortisol, udokotela wakho angase asikisele ukuhlolwa okukhethekile.
- Ukuhlolwa Kokukhuthaza I-ACTH: Lokhu kuhlola ukuthi izindlala zakho ze-adrenal zisabela kanjani 'kumyalo' (i-hormone ethi 'ACTH') evela endlaleni yakho ye-pituitary. Kufana nomphathi ohlola ukuthi isisebenzi senza into efanele yini uma sicelwa ukuba senze okuthile. Lokhu kwenziwa ikakhulukazi ukuthola imbangela yamazinga aphansi e-cortisol.
- Ukuhlolwa Kokucindezela I-Dexamethasone:Lokhu kufana nolunye uhlangothi lwalolo vivinyo. Kuhlola ukuthi amazinga aphezulu e-cortisol emzimbeni alawulwa yini ngokunikeza inani elincane lomuthi we-steroid obizwa ngokuthi ``(dexamethasone)''. Lokhu kusiza ukuthola ukuthi unesifo sikaCushing nokuthi sibangelwa yini isimila esise-pituitary gland noma kwenye indawo.
Uma udokotela wakho esola okuthile okufana nesimila, angakuthumela futhi ukuthi uyohlolwa nge-CT noma nge-MRI.
Ezinye izizathu zokuthi kungani imiphumela ingaba engavamile
I-Cushing's syndrome kanye nesifo sika-Addison yizimo ezingavamile. Kukhona nezimbangela ezivame kakhulu zamazinga e-cortisol angajwayelekile.
- Ukucindezeleka okukhulu
- Ukuzivocavoca ngokweqile
- Ukukhulelwa
- Ukukhuluphala ngokweqile
- Eminye imithi, njengamaphilisi okuvimbela inzalo
Ngakho-ke ungesabi ushintsho oluzumayo emphumeleni. Udokotela wakho uzokucabangela konke lokhu futhi akutshele isizathu sangempela.
Umlayezo Wokuya Nawe Ekhaya
- I-Cortisol akuyona nje kuphela 'i-hormone yokucindezeleka' yomzimba wethu, kodwa futhi iyi-hormone ebalulekile elawula umfutho wegazi, amazinga kashukela, kanye nokusetshenziswa komzimba.
- Amazinga e-cortisol ayahlukahluka kuye ngesikhathi sosuku. Ngokuvamile aphezulu ekuseni futhi aphansi ebusuku.
- Amazinga aphezulu kakhulu e-cortisol angaba uphawu lwe-Cushing's syndrome. Amazinga aphansi kakhulu angaba uphawu lwe-Addison's disease.
- Ukucindezeleka, ukuvivinya umzimba, ukukhulelwa, kanye neminye imithi nakho kungabangela ushintsho emazingeni e-cortisol.
- Uma udinga ukwenza ukuhlolwa kwe-cortisol, xoxa njalo nodokotela wakho ngemiphumela. Uzokunikeza isiqondiso esingcono kakhulu.
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