Uma umama wakho, ubaba wakho, noma umuntu oseduze nawe ehlushwa yisifo i-Alzheimer's, siyazi ukuthi kungaba nzima kangakanani. Amagama awakwazi ukuchaza ubuhlungu obuzwayo njengoba ubuka inkumbulo yakho iphela kancane kancane futhi imisebenzi yakho yansuku zonke iba nzima. Ezimweni ezinjalo, i-Galantamine umuthi okhethekile odokotela abawunikeza ukulawula izimpawu nokwenza impilo yesiguli ibe lula kancane. Ngakho-ke namuhla, ake sixoxe kafushane ngalo muthi, ukuthi ungawusebenzisa kanjani, nokuthi yini okufanele uyiqaphele.
Uhlobo luni lomuthi iGalantamine?
Kalula nje, iGalantamine umuthi osetshenziselwa ukwelapha i-dementia encane kuya kwephakathi ebangelwa yisifo i-Alzheimer's. Isiza kwezinye zezinqubo zokuxhumana kwemizwa ebuchosheni.
Into ebalulekile ukuthi lo muthi awukwazi ukwelapha ngokuphelele isifo i-Alzheimer's. Kodwa-ke, ungasiza ekunciphiseni ukuqhubeka kwalesi sifo futhi ulondoloze inkumbulo, ukunaka, kanye nekhono lokwenza imisebenzi yansuku zonke isikhashana. Lo muthi ungase ube ngaphansi kwamagama emikhiqizo afana neRazadyne noma iReminyl.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala imithi
Ngaphambi kokunikeza isiguli sakho iGalantamine, kubaluleke kakhulu ukunikeza udokotela incazelo ephelele yesimo sempilo yaso. Ikakhulukazi uma sinanoma yiziphi zalezi zimo ezilandelayo:
| Isimo sezokwelapha | Kungani kufanele utshele udokotela? |
|---|---|
| Isifo senhliziyo noma ukwehluleka kwenhliziyo | I-Galantamine inganciphisa kakhulu izinga lokushaya kwenhliziyo. |
| I-asthma noma ezinye izifo zamaphaphu | Kungase kube nobunzima obandayo bokuphefumula. |
| Isifo sesibindi noma sezinso | Umthamo kungadingeka ushintshwe ngoba uthinta ukususwa komuthi emzimbeni. |
| Ukuquleka | Lo muthi ungandisa kancane ingozi yokuba nesifo sokuwa. |
| Izilonda zesisu noma ukopha kwamathumbu | Kungakhuphula ukukhishwa kwe-asidi esiswini futhi kwenze isimo sibe sibi kakhulu. |
| Ubunzima bokuchama | Lesi simo singase sibe sibi kakhulu. |
| Ukungezwani neminye imithi noma ukudla | Qaphela ukuthi kungenzeka ukuthi kukhona ukungezwani komzimba neGalantamine. |
| Uma ukhulelwe, uzama ukukhulelwa, noma ungumama oncelisayo | Udokotela kufanele aqaphele imiphumela engaba khona embungwini noma enganeni. |
Ngingawusebenzisa kanjani lo muthi?
- Landela iseluleko sezokwelapha: Thatha umthamo njengoba nje udokotela wakho emyalile, ngesikhathi esifanele.
- Yithathe kanye nokudla: Ukuze unciphise ukucasuka kwesisu, kungcono ukuphuza lo muthi ngesikhathi sokudla noma ngemva kokudla. Gwinya iphilisi ngengilazi egcwele yamanzi.
- Ungayeki: Ngisho noma isiguli sizizwa singcono kancane, ungayeki ngokuzumayo ukuthatha imithi ngaphandle kweseluleko sikadokotela.
- Gcina kude nezingane: Lo muthi uvame ukunikezwa abantu abadala. Uma unikezwa izingane, kufanele unikezwe kuphela ngeseluleko esikhethekile sezokwelapha.
Wenzani uma uphuthelwa umthamo noma uthatha kakhulu?
Uma uphuthelwe umthamo: Thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo olandelayo ngesikhathi esijwayelekile. Ungalokothi uthathe umthamo ophindwe kabili. Uma uphuthelwe umuthi izinsuku ezingaphezu kwezintathu, khuluma nodokotela wakho ngaphambi kokuqala futhi.
Ukweqisa umthamo: Kukhona ukusola okuncane kokuthi uphuze umuthi omningi kakhulu.Uma ikhona, shayela ngokushesha iNational Poisons Information Centre eColombo National Hospital (inombolo yocingo 0112 686 143). Noma thatha isiguli uye esibhedlela esiseduze i-Emergency Treatment Unit (ETU) .
Imiphumela emibi engase ivele lapho uthatha umuthi
Njenganoma yimuphi umuthi, i-Galantamine ingabangela imiphumela emibi. Eminye yale miphumela ingaba mibi kakhulu, ngakho-ke kubalulekile ukuyiqaphela.
| Imiphumela emibi okufanele ibikwe kudokotela wakho ngokushesha | |
|---|---|
| 🔴 Ukungezwani okukhulu kwesikhumba (ukuqubuka kwesikhumba, ukulunywa, amabhamuza) | 🔴 Ukuvuvukala kobuso, izindebe, noma ulimi |
| 🔴 Ukushaya kwenhliziyo okuhamba kancane kakhulu noma okungajwayelekile | 🔴 Isiyezi esikhulu, ukulahlekelwa ukwazi kanye nokuwa |
| 🔴 Ubuhlungu obukhulu esiswini noma ukuhlanza | 🔴 Ukopha noma ukuphuka okungavamile, amabala abomvu/onsomi esikhumbeni |
| 🔴 Uhudo olubi kakhulu (uhudo) | 🔴 Ukwehlisa isisindo ngendlela engavamile |
| Ngokuvamile akuyona into engathi sína, kodwa tshela udokotela wakho uma iqhubeka. | |
| 🟢 Ikhanda elibuhlungu | 🟢 Isifiso sokudla |
| 🟢 Isicanucanu (ukuzizwa sengathi uhlanza) | 🟢 Uhudo oluncane (ikakhulukazi uma uqala umuthi) |
Izinto okufanele uzikhumbule uma usebenzisa umuthi
Lo muthi ngezinye izikhathi ungabangela isiyezi kanye nokozela . Ngakho-ke, uze wazi kahle ukuthi lo muthi uwuthinta kanjani umzimba, gwema imisebenzi edinga ukugxilisa ingqondo kakhulu, njengokushayela imoto noma ukusebenzisa imishini.
Eminye imithi engase ihlangane neGalantamine
Eminye imithi ingabangela izinkinga uma ithathwa nge-Galantamine. Ngakho-ke, tshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi leyo enqunywe abanye odokotela, imithi yokunciphisa izinhlungu ethengwa ngaphandle kwemithi kadokotela, amavithamini, kanye nemikhiqizo yamakhambi) . Qaphela kakhulu ngemithi elandelayo:
- Imithi efana ne-Atropine, i-Dicyclomine, ne-Scopolamine
- Ama-antifungal (isb. i-Ketoconazole)
- Eminye imithi yesifo senhliziyo (isib. i-Digoxin, i-Quinidine)
- Imithi yokucindezeleka noma ezinye izifo zengqondo
- Imithi enikezwa ukukhulula imisipha ngesikhathi sokuhlinzwa
Lolu hlu aluphelele, ngakho-ke kubaluleke kakhulu ukunikeza udokotela wakho ulwazi oluphelele .
Umlayezo Wokuya Nawe Ekhaya
- I-Galantamine ayilona ikhambi lesifo i-Alzheimer's, kodwa umuthi olawula izimpawu.
- Landela umthamo nesikhathi esinqunywe udokotela wakho. Ukuwuthatha kanye nokudla kunganciphisa ukucasuka kwesisu.
- Ngaphambi kokuqala umuthi, tshela udokotela ngazo zonke izimo zezempilo zesiguli kanye nayo yonke eminye imithi esiyithathayo.
- Uma uhlangabezana nemiphumela emibi kakhulu (njengezimpukane zesikhumba, ukushaya kwenhliziyo okuhamba kancane, ukulahlekelwa ukwazi), funa iseluleko sezokwelapha ngokushesha.
- Lo muthi ungowesiguli esinikezwe wona. Ungalokothi wabelane ngawo nabanye.
- Gwema imisebenzi eyingozi njengokushayela, ngoba kungase kube nesiyezi.
- Gwema ukuyeka imithi ngaphandle kweseluleko sikadokotela wakho.
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
💬 Amaphilisi/ama-capsule e-Galantamine (Galantamine / Razadyne) ayimithi yasiphi isifo?
Leli iphilisi elibaluleke kakhulu nelibalulekile elinikezwa iziguli ezisesigabeni sokuqala nesiphakathi seSifo i-Alzheimer's, esenzeka lapho zikhula, lapho inkumbulo yazo iphela khona ngokuphelele futhi zingaqondi lutho oluzungezile! Lokhu akukwazi ukwelapha isiguli ngokushesha/ukuvuselela ubuchopho, kodwa lo muthi wehlisa kakhulu izinga lokulahlekelwa yinkumbulo (umsebenzi wokuqonda) futhi usiza isiguli ukuthi senze umsebenzi waso.
💬 Lo muthi (iGalantamine) ubasiza kanjani abantu abane-Alzheimer's ukuthi balondoloze inkumbulo?
Isithunywa samakhemikhali 'i-Acetylcholine' sibalulekile ebuchosheni bethu ukuze silondoloze inkumbulo, ukufunda, kanye nokucabanga. Ebuchosheni beziguli ze-Alzheimer's, lokhu kuyabhujiswa/kuphele ngokushesha okukhulu. Ngemva kokuthatha lo muthi (i-Cholinesterase inhibitor), i-enzyme ephula lelo khemikhali iyavalwa, okuvumela i-acetylcholine eyengeziwe ukuthi iqoqeke ebuchosheni. Ngemuva kwalokho, imizwa ebuchosheni ingaxhumana/ivuselele izinkumbulo futhi.
💬 Yimiphi imiphumela emibi engaba khona yokuphuza lo muthi?
Njengoba leli khemikhali lihlasela ubuchopho kanye namathumbu, ukuliphuza kungabangela 'isicanucanu/ukuhlanza okukhulu, izinhlungu zesisu, i-anorexia, kanye nohudo oluqhubekayo' (ngakho qala ngomthamo omncane kuqala). Futhi, kubantu asebekhulile, kungabangela 'i-bradycardia' engazelelwe kanye nesiyezi, okungaholela ekuweni.
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