Ingabe ngezinye izikhathi uba nokunyakaza kwamanzi okuhlala izinsuku eziningi? Kanye nalokho, uzizwa ungakhululekile futhi ubuhlungu obukhulu esiswini sakho, akunjalo? Lesi yisimo esingakhulumi kakhulu ngaso, kodwa singathinta abantu abaningi. Yilokho okushiwo yi-microscopic colitis. Namuhla, sizokhuluma ngalokhu ngokuningiliziwe nangokulula kakhulu.

Kuyini i-Microscopic Colitis?

Kalula nje, i-microscopic colitis ukuvuvukala okungapheli (okuhlala isikhathi eside) kolwelwesi lwamathumbu akho amakhulu (okwaziwa nangokuthi ikholoni yakho). Igama elithi "colitis" lisho ukuvuvukala kwamathumbu amakhulu. Libizwa ngokuthi "microscopic" ngoba ukuvuvukala akubonakali ngeso lenyama. Kungabonakala ngokucacile kuphela nge-microscope.

Lokhu futhi uhlobo lwesifo samathumbu esivuvukalayo (i-IBD). Kodwa kuhlukile kancane kwezinye izinhlobo ze-IBD. Amaseli asemathunjini akho ahlala ecasukile . Uphawu oluyinhloko uhudo oluvame ukuba namanzi. Njengezinye izifo ezingamahlalakhona, lungafika luhambe, bese luhamba, bese lubuya. Okusho ukuthi, izinto ezithile (esizibiza ngokuthi "izisusa") zingenza lesi sifo sibe sibi kakhulu, ngezinye izikhathi siyahamba sodwa, bese sibuya ngemva kwesikhashana. Nakuba kungaba yisimo sokuphila konke, ngokuvamile singalawulwa kahle ngokwelashwa .

Ubani okungenzeka kakhulu ukuthi athole lokhu?

Lesi simo singakhula kunoma ubani, kodwa abanye abantu banamathuba amaningi okuba naso.

• Lokhu kuvame ukubonwa kubantu abadala .
• Kutholakale nokuthi abesifazane bakhula kakhulu kunabesilisa.
• Le ngozi iphakeme nakubantu ababhemayo .
• Kungaphinde kwenzeke nakubantu abanezifo ezithile zokuzivikela komzimba, ikakhulukazi isifo se-celiac (ukungezwani komzimba ne-gluten).

I-microscopic colitis ngokuvamile yayicatshangwa ukuthi ayivamile kakhulu kunezinye izifo zamathumbu ezivuvukalayo. Kodwa-ke, njengoba kudingeka i-biopsy yamathumbu amakhulu ukuze kutholakale ukuthi iyimbangela enembile, manje sekukholelwa ukuthi abantu abaningi bangaba nalesi simo kunalokho esasikucabanga .

Ingabe lesi yisifo esiyingozi?

Cha, uma kuqhathaniswa nezinye izinhlobo ezimbi ze-IBD, i-microscopic colitis ayibhekwa njengesifo esibi nesisongela impilo. Kodwa-ke, isifo sohudo esiqhubekayo nesibi singaholela ekuphelelweni amanzi emzimbeni, ekunciphiseni isisindo, futhi mhlawumbe nasekungondleki kahle. Kodwa-ke, ngokuvamile asibi kakhulu kangako.

Lesi yisimo esifika sidlule futhi esingalawulwa ngemithi, ngakho-ke asikho isidingo sokwesaba. Kodwa-ke, ukuphila nokungakhululeki esiswini ngemva kokudla ngakunye kungaba nomthelela ezingeni lempilo yakho . Ngakho-ke, kubalulekile ukuqaphela lokhu.

Yiziphi izinhlobo eziyinhloko ze-microscopic colitis?

Odokotela bangaqinisekisa lesi sifo kuphela ngokubheka isampula yezicubu ezivela olwelwesini lwamathumbu akho (i-intestinal mucosa) ngaphansi kwe-microscope. Base bengakwazi ukubona izici ezithile zalawo maseli. Lezi zimpawu zisetshenziselwa ukunquma izinhlobo zesifo. Okwamanje kunezinhlobo ezimbili eziyinhloko ezitholakale. Kuxoxwa ngezinye eziningana.

• I-Collagenous colitis: Izicubu ezixhumeneyo ezingaphakathi kwekholoni yakho zakhiwe yi-collagen ne-elastin. Kulolu hlobo, ama-collagen band angaphakathi kwekholoni yakho aba makhulu ngendlela engavamile. Lokhu kufana nendlela i-collagen ne-elastin ezivuvukala ngayo kwezinye izifo zezicubu ezixhumeneyo, njenge-rheumatoid arthritis. Lezi zimo zokuzivikela komzimba ziyabonakala nakubantu abane-microscopic colitis.

• I-Lymphocytic colitis: Kulolu hlobo, kunokwanda okungavamile kwenani lama-lymphocyte, uhlobo lweseli olwelwesini lwekholoni (i-epithelium). Ama-lymphocyte awuhlobo lwamaseli amhlophe egazi. Ayingxenye yesimiso sethu somzimba sokuzivikela futhi asivikela ezifweni. Kujwayelekile ukuthi inani lamaseli amhlophe egazi lande uma kukhona ukuvuvukala okuhlobene nesimiso somzimba sokuzivikela.

Ingxenye engcono kakhulu ukuthi izimpawu zazo zombili izinhlobo ziyafana. Futhi ukwelashwa kuyafana. Umehluko kuphela uma uzibheka ngaphansi kwe-microscope. Abanye ososayensi bacabanga ukuthi empeleni lezi yizimo ezimbili zesimo esifanayo. Ngezinye izikhathi, ungabona ngisho nezimpawu zazo zombili izinhlobo kumuntu oyedwa. Lokhu kubizwa ngokuthi "i-incomplete microscopic colitis."

Ngaphezu kwalokho, abanye abantu bacabanga ukuthi isimo esibizwa ngokuthi i-mastocytic enterocolitis kufanele sibhekwe njengohlobo lwe-microscopic colitis. Sinezimpawu eziningi ezifanayo. Kodwa-ke, i-"enterocolitis" isho ukuthi ayithinti nje kuphela amathumbu amakhulu, kodwa futhi namathumbu amancane. I-"Mastocytic" isho ukuthi kukhona ukwanda okungavamile kolunye uhlobo lweseli lokuzivikela olubizwa ngokuthi amaseli e-mast olwelwesini lwamathumbu.

Ziyini izimpawu zalokhu?

Uphawu oluyinhloko noluvelele kakhulu lwe-microscopic colitis ukuhamba kwamathumbu okungapheli, okunamanzi.Ngokuvamile, ungaba nokunyakaza kwamathumbu kahlanu kuya kweshumi ngosuku. Abanye abantu bangase babe nokuningi noma okuncane kunalokho. Akuvamile kakhulu ukuthi kube ne-colitis encane eyenzeka ngaphandle kokunyakaza kwamathumbu noma ngokuqunjelwa. Ezimweni ezinjalo, itholakala ngengozi ngenkathi ufuna okunye.

Ngaphezu kwezimpawu eziyinhloko, kunemiphumela emibi eminingana evamile engabonakala:

• Ubuhlungu besisu kanye nokuqaqamba kwesisu.
• Ukuvuvukala kwesisu nokuqunjelwa.
• Isidingo esiphuthumayo sokuya endlini yokugezela kanye nobunzima bokubamba isihlalo ngemuva.
• Ukuzwa imisindo yamathumbu (njengokugwinya kwesisu).
• Abanye abantu banenkinga yokudla ukudla okuqukethe i-gluten (njengesinkwa nama-noodle).
• Ukuzizwa ukhathele ngaso sonke isikhathi (Ukukhathala).

Uma isimo sibi kakhulu, izimpawu ezifana nalezi:

• Ukuphelelwa amanzi emzimbeni.
• Isicanucanu nokuhlanza.
• Ukwehlisa isisindo.

Ngaphezu kwalokhu, abanye abantu bakhuluma ngezinye izici:

• Ukuqaqamba kwemisipha noma ubuhlungu bemisipha.
• Ubuhlungu nokuqina kwamalunga.
• Ubuhlungu bekhanda noma i-migraines.
• Izilonda zomlomo.
• Ukuqubuka kwesikhumba.
• Isicanucanu, i-acid reflux.
• Ama-lymph node avuvukele.
• Izinkinga ze-thyroid.
• Izinkinga zesimiso sezinzwa (isb., ubunzima bokuhamba - `(ataxia)`).

Okubalulekile: Uma unesinye noma ngaphezulu kwalezi zimpawu, akusho ukuthi unesifo sohudo esincane kakhulu. Kodwa-ke, kungcono ukufuna iseluleko sezokwelapha, ikakhulukazi uma unesifo sohudo esiqhubekayo.

Yiziphi izizathu zalokhu?

Ososayensi abakayitholi imbangela eqondile yalokhu, kodwa bacabanga ukuthi kunezici eziningana ezingaba nomthelela:

• Ukuchayeka kumagciwane athile, ubuthi bamagciwane, kanye namagciwane.
• Impendulo yokuzivikela komzimba iwukusabela okwenzeka ngenxa yephutha ohlelweni lokuzivikela lomzimba wethu. Okusho ukuthi, uhlelo lokuzivikela lusebenza ngokumelene namaseli ethu.
• Ufuzo. Lokho kusho ukuthi kungaba yinto evela ezizukulwaneni ngezizukulwane.

Ucwaningo oluthile lusikisela ukuthi eminye yemithi esiyisebenzisayo ingase ibe nomthelela kule nkinga. Isibonelo:

• Imithi engeyona eye-steroidal yokulwa nokuvuvukala (ama-NSAID) - isibonelo, imithi yobuhlungu efana ne-ibuprofen ne-diclofenac.
• I-Proton pump inhibitors (PPIs) - imithi efana ne-Omeprazole, esetshenziselwa ukwelapha i-gastritis.
• Ama-Selective serotonin reuptake inhibitors (SSRIs) - imithi esetshenziselwa ukwelapha izifo zengqondo njengokucindezeleka.
• Ukwelashwa kokushintsha ama-hormone (HRT).
• Ama-beta blocker - eminye imithi esetshenziselwa ukwelapha umfutho wegazi ophakeme.
• Ama-statin - Imithi yokwehlisa i-cholesterol.

Akuwona wonke umuntu othatha le mithi ozobhekana nalesi simo. Kodwa-ke, kucatshangwa ukuthi lokhu kungaba yimbangela. Uma uthatha le mithi, ungayeki ukuyithatha ngaphandle kokukhuluma nodokotela wakho.

Ungasithola kanjani lesi sifo ngokunembile? (Ukuxilongwa)

I-Microscopic colitis ivame ukutholakala ngudokotela wezifo zamathumbu. Uzoqala ngokukubuza ngomlando wakho wezokwelapha kanye nanoma yimiphi imithi oyithathayo njengamanje. Ngemuva kwalokho, bangenza izivivinyo ezahlukahlukene ukuze babone ukuthi zikhona yini ezinye izinto ezingaba imbangela yesimo sakho.

• Ukuhlolwa kwegazi
• Ukuhlolwa kwendle
• Mhlawumbe ukuhlolwa kwezithombe

Uma lezi zivivinyo zingatholi imbangela ecacile, udokotela uzobe esencoma i-colonoscopy kanye ne-biopsy . Lena yindlela eyinhloko yokuqinisekisa i-colitis encane.

Ngesikhathi sokuhlolwa kwekholoni, udokotela wakho uzofaka ithuluzi elide neliguquguqukayo (elibizwa ngokuthi i-colonoscope) nge-rectum yakho kanye namathumbu akho amakhulu. Uzolaliswa phakathi nale nqubo, ngakho ngeke uzwe ubuhlungu. Ithuluzi elincane lizofakwa ngethuluzi bese kuthathwa ingxenye encane yezicubu (i-biopsy) olwelwesini lwekholoni lakho bese ihlolwa ngaphansi kwe-microscope. Lena ukuphela kwendlela yokubona ukuthi une-microscopic colitis.

Iphathwa kanjani?

Ukwelashwa kungahluka kuye ngezimpawu zakho kanye nobunzima bazo. Abanye abantu kungadingeka benze izinguquko ezincane ekudleni kwabo nasendleleni yabo yokuphila. Abanye bangadinga imithi ethengiswa ngaphandle kwemithi kadokotela (OTC) noma imithi kadokotela.

Cabanga nje, kwabanye abantu, izimpawu zivela ngokuzumayo bese zinyamalala zodwa. Kwabanye, ukulawula ukudla kwabo kungaba impumuzo ebalulekile. Kwabanye, kungase kudingeke baphuze imithi kuphela ngesikhathi sokuqubuka kwesifo, noma kungase kudingeke baphuze imithi njalo.

Eminye imithi evame ukusetshenziswa:

• Imithi eqinisa indle futhi inciphise ukuvama kokuhamba kwamathumbu (`Izinto ezibangela ukukhukhumala`): Isibonelo, izinto ezifana ne-Isabgol `(psyllium).`
• Imithi yokulwa nohudo: Imithi enciphisa izinga lokufinyela kwamathumbu futhi ilawule uhudo : Isibonelo, i-loperamide noma i-diphenoxylate.
• I-Bismuth subsalicylate (njenge-Pepto Bismol®): Yesifo sohudo, isilungulela, isicanucanu, kanye nokungagayeki kahle kokudla.
• I-Budesonide:Lolu uhlobo lwe-corticosteroid. Lumuncwa emzimbeni emathunjini amakhulu, lapho lunciphisa khona ukuvuvukala.
• I-Mesalamine: Empeleni lo muthi we-ulcerative colitis, esinye isifo samathumbu esivuvukalayo. Kodwa futhi usetshenziselwa ukunciphisa ukuvuvukala nobuhlungu.
• Ama-sequestrant e-bile acid (isb., i-colesevelam, i-colestipol): Lawa anikezwa uma unenkinga lapho umzimba wakho ungamunci kahle i-bile (i-bile acid malabsorption).

Uma imithi engenhla ingasizi kakhulu, futhi udokotela wakho ecabanga ukuthi kungenzeka ukuthi ibangelwa imbangela yokuzivikela komzimba, khona-ke eminye imithi ehlose amasosha omzimba ingasikiselwa:

• Ama-immunosuppressants.
• Izithibi ze-TNF (isib. i-adalimumab, i-infliximab).
• I-Cromolyn sodium (ihlasela amaseli e-mast, ikakhulukazi ku-mastocytic enterocolitis).
• I-naltrexone ephansi.

Iseluleko esengeziwe ongasithola kudokotela wakho:

• Uma okwamanje uthatha eminye imithi, cabanga ngokushintsha imithamo yayo noma ukushintsha imithi.
• Ukuyeka ukubhema ngokuphelele.
• Ukuzama ukuthola ukuthi yikuphi ukudla okubangela ukungezwani komzimba nokuthi yikuphi okwenza izimpawu zakho zibe zimbi kakhulu.

Ingabe lesi sifo sizophulukiswa ngokuphelele?

Hhayi unomphela. Kodwa, ungahlala ungenazo izimpawu isikhathi eside . Lokhu sikubiza ngokuthi "ukuxolelwa" kwalesi sifo. Lokhu kuxolelwa kungahlala izinyanga, ngisho neminyaka. Kodwa, njenganoma yisiphi isifo esingamahlalakhona, kungabuya ngenxa "yezinto ezibangela" isifo. Uma uthola izimbangela zakho, unganciphisa ukuqubuka kwesifo.

Ukuqhuma kwesikhumba kuthatha isikhathi esingakanani ?

Lokhu kuyahlukahluka kuye ngomuntu nomuntu. Kodwa-ke, isikhathi esivamile sokuqubuka kwesikhumba singahlala kusukela ezinsukwini ezimbalwa kuya emavikini ambalwa. Abantu abaningi bakwazile ukunciphisa ubude nobunzima balokhu kuqubuka kwesikhumba ngokugwema ukudla namakhemikhali abacasulayo, nangokuthatha imithi lapho kudingeka. Qiniseka ukuthi ukhuluma nodokotela wakho uma izimpawu zakho ziba zimbi kakhulu.

Yikuphi ukudla neziphuzo ezingcono kakhulu kumuntu onesifo sofuba esingabonakali kahle?

Akukho "ukudla okuqondile kwe-microscopic colitis" kwe-microscopic colitis. Kodwa-ke, kungasiza ekuphatheni izimpawu zakho ngokunciphisa ukudla okuzenza zibe zimbi kakhulu nokwengeza ukudla okwengeziwe okunciphisa ukuvuvukala. Ukudla kwakho okukhethekile kuzohluka kuwe. Kuzothatha ukuzijwayeza ukuthola ukuthi yini ekusebenzelayo. Udokotela wakho angase asikisele izinto ezinjengalezi:

Ukuqeda ukudla okuvamile ukubangela ukungezwani komzimba

Nazi ezinye zokudla eziye zabonakala njengezikwazi ukwandisa izimpawu ze-microscopic colitis:

• Utshwala.
• I-caffeine (etholakala ekhofini, etiyeni, nakwezinye iziphuzo ezibandayo).
• I-Gluten (iphrotheni etholakala kokusanhlamvu okufana nokolweni, ibhali, kanye ne-rye - ezintweni ezifana nesinkwa, i-pasta, namakhekhe).
• Ubisi nemikhiqizo yobisi.
• Ushukela.
• Izithambisi zokwenziwa.

Ukudla okunamafutha amancane kanye ne-fiber ephansi

Ngesikhathi sokushaqeka, abanye odokotela batusa "ukudla okuthambile kwesisu." Lokhu kuhilela ukudla ukudla okunamafutha amancane kanye ne-fiber encane. Lokhu kunciphisa umthwalo womsebenzi ohlelweni lwakho lokugaya ukudla. Kodwa-ke, okunye ukudla okukulolu hlobo lokudla kungase kungakhululeki kuwe.

Ukudla kokuqeda

Enye indlela yokuthola ukuthi yikuphi ukudla okubangela ukungezwani komzimba ukuzama ukudla okuhlukile. Isibonelo, ukudla okune-FODMAP ephansi. Lena indlela yesikhashana. Kulokhu, uqeda ngokuphelele amaqembu athile okudla bese uwabuyisela kancane kancane ngalinye ngalinye ukuze ubone ukuthi yikuphi okuzwela kakhulu. Kubalulekile ukufuna isiqondiso kuchwepheshe wezokudla obhalisiwe lapho wenza lokhu.

Ukudla okulwa nokuvuvukala

Ukudla okuthile, njengokudla okunamafutha amaningi angagcwalisiwe, kuye kwatholakala ukuthi kunciphisa ukuvuvukala emzimbeni. Ukudla kwaseMedithera kuyisibonelo esihle sokudla okunjalo okulwa nokuvuvukala. I-Turmeric nayo iyisengezo esihle ekudleni kwakho, njengoba inezakhiwo zokulwa nokuvuvukala.

Ingabe ama-probiotic alungele lokhu?

Ama-probiotics ayenconywa ngaphambilini njengokwelashwa kwe-microscopic colitis. Kodwa-ke, iziqondiso zamanje aziwancomi ngoba kudingeka ucwaningo olwengeziwe. Ngakho-ke, ungawasebenzisi ama-probiotics ngaphandle kweseluleko sikadokotela wakho.

I-Microscopic colitis yisimo esingakaqondakali kahle. Kwezinye izifo zamathumbu ezivuvukalayo, yisona esingaziwa kakhulu. Kodwa-ke, ososayensi manje basola ukuthi singase sibe sivamile njengezinye. Akukho ucwaningo oluqondile ngaso, futhi okwamanje akukho mithi eqondiwe ngaso. Ngenhlanhla, singalawulwa ngokwelashwa kwamanje. Ngomzamo omncane, ukuthola imithi efanele kanye nokudla, ungakwazi ukuphatha izimpawu zakho kahle uma zivela.

Okokugcina, izinto ezimbalwa okufanele uzikhumbule

• I-Microscopic Colitis yisimo esilawulekayo , ngakho ungesabi.
• Ukuze kutholakale lokhu ngokunembile, kudingeka i-colonoscopy kanye ne-biopsy.
• Sebenza nodokotela wakho ukuthola ukwelashwa okukusebenzela kahle kakhulu.
• Kubaluleke kakhulu ukuhlonza ukudla, iziphuzo, nezinye izinto ezikugulisayo (izinto ezikubangela ukugula).
• Uma unezimpawu, ungazifihli bese uhlupheka, kodwa funa iseluleko sezokwelapha. Awuwedwa!

I-Microscopic Colitis, Uhudo, Ubuhlungu besisu, Ukuvuvukala kwamathumbu, I-Colitis, Ukungezwani nokudla, I-Gastroenterology