Mhlawumbe wawuhlolwe igazi ngenxa yesinye isifo. Noma mhlawumbe kwakuwukuhlolwa kwezokwelapha okuvamile kwaminyaka yonke. Ngaleso sikhathi, udokotela wayekutshela ukuthi, "Uneprotheni engajwayelekile egazini lakho ebizwa ngokuthi 'i-M protein', futhi lesi simo sisibiza ngokuthi i-MGUS." Uma noma ubani ezwa into efana nale, uyashaqeka futhi esaba kancane. Kuvamile kakhulu ukuthi kuvele imibuzo eminingi engqondweni, njengokuthi 'Ingabe lo mdlavuza?', 'Kuzokwenzekani kimi manje?', 'Ingabe kukhona ikhambi lalokhu?' Kodwa ungakhathazeki. Namuhla, sizoxoxa ngokuthi iyini i-MGUS, ingabe iyingozi ngempela, nokuthi yini okufanele siyenze ngalesi simo ngendlela elula kakhulu ongayiqonda.
Iyini ngempela i-MGUS?
Kalula nje, i-MGUS (i-Monoclonal Gammopathy of Undetermined Significance) yisimo lapho igazi lakho likhiqiza iphrotheni engajwayelekile. Sibiza le phrotheni engajwayelekile ngokuthi iphrotheni ye-M . Lokhu kungatholakala ngokuhlolwa kwegazi noma ngezinye izikhathi ngokuhlolwa komchamo.
Kulungile, manje ake sijule kancane sibone ukuthi lokhu kwenzeka kanjani.
Ake sithi sinebutho lokuzivikela emizimbeni yethu. Uhlobo olulodwa olukhethekile lwamasosha kuleli butho amaseli e-plasma . Empeleni lawa uhlobo lwamaseli amhlophe egazi. Umsebenzi wawo oyinhloko ukwenza izikhali ezikhethekile zamaprotheni ezibizwa ngokuthi ama-antibodies ukulwa namagciwane abangela izifo (amagciwane, amagciwane, njll.) angena emizimbeni yethu. Lawa ma-antibodies yiwo asivikela ezifweni ngokubamba nokubhubhisa amagciwane.
Kodwa kumuntu one-MGUS, amanye ala maseli e-plasma 'ahamba kabi' kancane. Okusho ukuthi, esikhundleni sokwenza ama-antibodies ajwayelekile, anempilo, la maseli aqala ukwenza inani elikhulu leprotheni efanayo, engenamsebenzi, nengajwayelekile. Yilokho esikubiza ngokuthi iphrotheni ye-M.
Into ebalulekile ukuthi i-MGUS ayiyona umdlavuza . Kodwa odokotela bayibheka njengesandulela somdlavuza esingenabungozi. Okusho ukuthi, ingaba ukuqala komdlavuza. Kodwa ungesabi la mazwi. Iningi labantu abane-MGUS ngeke liphinde libe nesifo esibi empilweni yabo.
Ingabe zikhona izimpawu ze-MGUS?
Nansi into emangalisayo. Abantu abaningi abane-MGUS abanazo izimpawu . Yingakho lesi simo sivame ukutholakala ngengozi, ngesikhathi sokuhlolwa kwegazi okwenziwe ngesinye isizathu. Ungase ungezwa mehluko. Ngakho-ke kuvamile ukucabanga ukuthi, "Ngiphilile," uma uthola ukuthi une-MGUS. Lokho kungenxa yokuthi lawa maprotheni e-M avame ukuba khona egazini, ngaphandle kokulimaza umzimba.
Kungani i-MGUS ikhula? Yiziphi izici eziyingozi?
Eqinisweni, odokotela abakakazi kahle ukuthi kungani la maseli e-plasma eqala ukuziphatha ngale ndlela engavamile. Kuseyimfihlakalo. Kodwa ucwaningo luthole ukuthi abanye abantu basengozini enkulu yokuba nalesi simo.
Izinto ezandisa ingozi yokuthola i-MGUS
- Ubudala: I-MGUS iba yinto evamile njengoba ukhula. Ivame kakhulu uma usuneminyaka engu-50. Lapho usuneminyaka engu-70, cishe abantu aba-5 kwabayi-100 bangase babe nalesi simo.
- Ubulili: Amadoda anamathuba amaningi okuthola i-MGUS kunabesifazane.
- Uhlanga: Lesi simo sivame kakhulu ezinhlanga ezithile, ikakhulukazi abantu abamnyama .
- Umlando womndeni: Uma isihlobo esiseduze (umama, ubaba, umfowabo noma udadewabo) sinomdlavuza wegazi njenge-MGUS noma i-multiple myeloma , usengozini enkulu kancane yokuthola lesi simo.
- Izici Zemvelo: Abantu abanomlando wokuchayeka ezibulala-zinambuzane noma ezibulala-zinambuzane bangase babe sengozini enkulu.
- Ezinye izifo: Abantu abanezifo ezithile zokuzivikela komzimba nabo bangase babe sengozini.
- Ukuchayeka emisebeni: Ukuchayeka emisebeni eningi kakhulu nakho kungaba yimbangela yengozi.
Yiziphi izinkinga ezingaba khona ze-MGUS?
Lena yinto wonke umuntu ayicabangayo futhi ayesaba kakhulu. Njengoba kushiwo ngaphambili, i-MGUS ayiwona umdlavuza. Kodwa-ke, kubantu abambalwa, lesi simo singaba yisifo esibi kakhulu ngokuhamba kwesikhathi.
Abantu abangaba ngu-20 kuya ku-25 kwabayi-100 abane-MGUS ekugcineni bazoba nesifo esibi esihlobene negazi. Lokho kusho ukuthi abantu abangu-75-80 kwabayi-100 ngeke babe nezinkinga.
Izifo eziyinhloko ezingakhula njengoba i-MGUS iqhubeka yilezi:
- I-Multiple Myeloma: Lena inkinga evame kakhulu. Umdlavuza wamaseli e-plasma.
- I-Amyloidosis: Isifo lapho amaprotheni e-M efakwa khona ezithweni ezahlukene zomzimba bese ezilimaza.
- I-Waldenstrom macroglobulinemia: Lolu futhi uhlobo olungavamile lomdlavuza wegazi.
- I-leukemia ye-lymphocytic engapheli: Olunye uhlobo lomdlavuza wegazi.
Into ebalulekile ukuthi akuwona wonke umuntu othola i-multiple myeloma othola i-MGUS kuqala. Kodwa akuwona wonke umuntu othola i-MGUS othola i-multiple myeloma.
Ngaphezu kwalokho, i-MGUS ingandisa kancane ingozi yezinye izinkinga zempilo:
- Amahlule egazi
- Ukulahlekelwa yithambo noma ukwaphuka
- Ukutheleleka okuvamile
- Izinkinga zezinso
- Ukulimala kwemizwa (i-peripheral neuropathy): Lokhu kungabangela ukungazweli kanye nokuthuthumela ezithweni.
Udokotela uhlonza kanjani i-MGUS?
Udokotela wakho uzokwenza ukuhlolwa kwegazi nomchamo ukuhlola ukuthi kukhona yini iphrotheni ye-M. Uma lokho sekuqinisekisiwe, bazohlola ingozi yokuthi lesi simo sibe umdlavuza. Lokhu kuzobheka izici ezintathu eziyinhloko:
1. Inani leprotheyini ye-M egazini: Uma izinga leprotheyini ye-M lingaphezu kuka-1.5 g/dL (amagremu nge-deciliter ngayinye), ingozi iphakeme kancane.
2. Uhlobo lweprotheni i-M: Kunezinhlobo ezahlukene zeprotheni i-M (ebizwa ngokuthi izinhlobo ze -Immunoglobulin (Ig) . Ezinye izinhlobo zinamathuba amaningi okubangela izifo ezingathi sína kunezinye.
3. Amazinga okukhanya angena-serum (FLC): Lena enye iphrotheni ekhiqizwa amaseli e-plasma. Ukuhlolwa kwegazi okukhethekile ( ukuhlolwa kokukhanya okungena-serum (FLC) ) kungabona amazinga angajwayelekile alawa.
Umuntu onazo zonke lezi zici ezintathu usengozini enkulu yokuba nomdlavuza. Kodwa umuntu ongenazo lezi zici usengozini encane kakhulu. Udokotela wakho uzokuchazela ukuthi ukuliphi iqembu eliyingozi ngokusekelwe emiphumeleni yalezi zivivinyo.
Ingabe ikhona indlela yokwelapha i-MGUS?
Nazi izindaba ezinhle: Iningi labantu abane-MGUS alidingi ukwelashwa.
Ngakho-ke wenzani? Udokotela wenza lokho okubizwa ngokuthi "ukulinda ngokuqapha" noma "ukuqapha okusebenzayo." Kalula nje, "ukulinda ngokuqapha."
Lokho kusho ukuthi, ngaphandle kokukunikeza imithi, amazinga akho e-Blood M protein nezinye izinto ahlolwa njalo ngesheduli emisiwe.
- Ngokuvamile, ukuhlolwa kwegazi kuyalelwa njalo ezinyangeni ezintathu kuya kweziyisithupha ngonyaka wokuqala.
- Uma konke kuzinzile, ungacela ukuhlolwa njalo ezinyangeni eziyisithupha noma kanye ngonyaka .
Inhloso eyinhloko yokuhlolwa njalo kanjena ukuthola izimpawu zokuqala ze-MGUS ephenduka isimo esibucayi. Uma kukhona izinguquko eziqashelwayo, ukwelashwa kungaqalwa kusenesikhathi. Lokho kuyinzuzo enkulu.
Uma unenye inkinga ngaphezu kwe-MGUS, njengobuthakathaka bamathambo, udokotela wakho uzokunikeza ukwelashwa okuhlukile kwalokho.
Ngingambona nini udokotela?
Uma une-MGUS, udokotela wakho uzokunikeza izinsuku ezithile zokuhlolwa kwakho. Qiniseka ukuthi uya kulezo zinsuku. Ngaphezu kwalokho, uma uhlangabezana nanoma yiziphi izimpawu ezingavamile, bona udokotela wakho ngokushesha, kunokulinda i-aphoyintimenti yakho elandelayo yasemtholampilo. Lezi zimpawu zingaba uphawu lokuthi isimo sakho siya siba sibi kakhulu.
Naka ngokukhethekile izimpawu ezibalwe ngezansi.
| Izimpawu okufanele uziqaphele | Incazelo kanye nembangela engaba khona |
|---|---|
| Ukukhathala ngokweqile ngaphandle kwesizathu | Ukukhathala okuhlukile kokukhathala okuvamile futhi okungapheli kungakhathaliseki ukuthi ulala kangakanani. Kungase kube ngenxa ye-anemia (ukuntuleka kwegazi). |
| Ubuhlungu bethambo | Ubuhlungu, ikakhulukazi esifubeni, emhlane, noma ezimbanjeni. Lolu uphawu olubalulekile lwe-multiple myeloma. |
| Ukwehlisa isisindo okungachazeki | Uma ulahlekelwa isisindo ngokuzumayo ngaphandle kokuzama. |
| Ukutheleleka okuvamile | Uma uvame ukuthola umkhuhlane kanye nomkhuhlane ngenxa yobuthakathaka besimiso somzimba sokuzivikela. |
| Ukuqubuka noma ukudumba okulula | Ukopha ngisho noma kungukulimala okuncane noma ukubonakala kwamabala aluhlaza okwesibhakabhaka (imivimbo) ngaphansi kwesikhumba. |
| Ukuqaqamba noma ukungakhululeki emilenzeni | Ukulimala kwemizwa (i-peripheral neuropathy) kungabangela izimpawu ezinjengalezi ezandleni nasezinyaweni. |
| Ikhanda elibuhlungu, isiyezi, izinguquko zombono | Izimpawu ezinjengalezi zingavela ngenxa yokuqina kwegazi okubangelwa yi-M protein. |
Ukuxilongwa kwe-MGUS kungaba yinto edidayo kancane. Wona kanye amagama athi "ukubaluleka okunganqunywanga" akuyo akutshela ukuthi kusekuningi esingakwazi ngakho. Ucwaningo lusaqhubeka ukuthola ukuthi kungani kungathi sína kwabanye abantu hhayi kwabanye.
Kodwa into engcono kakhulu ukuthi, ngentuthuko kwezesayensi yezokwelapha namuhla, ungahlola ubungozi bakho kusenesikhathi. Futhi ngenxa yokuthi uqashwe njalo, noma yiziphi izinguquko zingatholakala esiteji sokuqala. Ngakho into engcono kakhulu ongayenza ukunciphisa ukwesaba kwakho bese ulandela imiyalelo kadokotela ngqo.
Umlayezo Wokuya Nawe Ekhaya
- I-MGUS akuyona umdlavuza, kodwa yisimo esingaphambi komdlavuza esingaba umdlavuza.
- Iningi labantu abane-MGUS alinazo izimpawu futhi alibi nezinkinga ezinkulu empilweni yabo yonke.
- Into ebaluleke kakhulu ukwenza ukuhlolwa kwegazi nomchamo wakho ngezikhathi ezihleliwe, njengoba udokotela wakho encoma. Lokhu kubizwa ngokuthi 'ukulinda ngokuqapha'.
- Uma uhlangabezana nezimpawu ezintsha, ezingavamile (ikakhulukazi ubuhlungu bamathambo, ukukhathala okukhulu, ukwehla kwesisindo), bona udokotela wakho ngokushesha, ngaphandle kokulinda i-aphoyintimenti yomtholampilo olandelayo.
- Ungesabi ngokungadingekile lesi simo. Into ebaluleke kakhulu ukuba ngaphansi kokuqashwa okufanele kwezokwelapha. Khuluma nodokotela wakho nganoma yimiphi imibuzo noma ukwesaba ongase ube nakho.
💬 Comments (0)
Awekho amazwana athunyelwe okwamanje. Faka amazwana akho lapha okokuqala ngqa.
Engeza amazwana akho