Uma udokotela wakho ekutshelile noma othile emndenini wakho ukuthi une-Chronic Myelogenous Leukemia (CML), uhlobo lomdlavuza wegazi, kungenzeka ukuthi uke wezwa ngomuthi obizwa ngokuthi i-Nilotinib. Lo muthi obaluleke kakhulu, okhethekile. Ngakho-ke namuhla, sizokhuluma kalula nangokucacile ngalokho okudingeka ukwazi lapho usebenzisa lo muthi, ukuthi uwusebenzisa kanjani ngendlela efanele, nokuthi yimiphi imiphumela emibi ongayilindela.
Kuyini i-Nilotinib?
Kalula nje, i-Nilotinib umuthi othize ovimba ukukhula kwamangqamuzana omdlavuza. Sibiza lezi zinhlobo zemithi ngokuthi "ukwelashwa okuqondiwe." Okusho ukuthi, lo muthi uya ngqo ekuqondiseni amaprotheni athile kumaseli omdlavuza, uwavimbe ekusebenzeni, futhi ulawula ukuhlukana nokukhula kwamangqamuzana omdlavuza.
Lo muthi usetshenziswa kakhulu ukwelapha uhlobo lwe-leukemia olubizwa ngokuthi i-Chronic Myelogenous Leukemia (CML) . Uphinde uthengiswe ngaphansi kwegama elithi Tasigna .
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala imithi
I-Nilotinib iyisidakamizwa esinamandla kakhulu. Ngakho-ke, ngaphambi kokuqala lokhu kwelashwa, udokotela wakho kuzodingeka abe nesithombe esiphelele sempilo yakho. Uma unezinye zezimo ezilandelayo, qiniseka ukuthi wazisa udokotela wakho.
| Isimo esingasebenza kuwe |
|---|
| Isifo sikashukela |
| Izimo ezifana nesifo senhliziyo, ukungalingani kwesigqi senhliziyo, noma i-Long QT syndrome. |
| Isifo sesibindi |
| Uma unomlando we-pancreatitis. |
| Uma unezinga eliphansi le-potassium noma i-magnesium egazini lakho. |
| Uma unezinkinga ngokujikeleza kwegazi emilenzeni. |
| Uma isisu sisusiwe ngokuphelele ngokuhlinzwa (i-Total Gastrectomy). |
| Uma une-allergy ku-nilotinib, i-lactose, i-gelatin, noma yimuphi omunye umuthi noma ukudla. |
| Uma ukhulelwe, uzama ukukhulelwa, noma uncelisa. |
Ngiyisebenzisa kanjani ngempela le mithi?
Ukuze uthole okuningi kulo muthi, kubaluleke kakhulu ukuwusebenzisa ngendlela efanele.
- Thatha isisu esingenalutho: Lena yinto ebaluleke kakhulu. Kufanele uthathe umuthi okungenani ihora elilodwa ngaphambi noma amahora amabili ngemva kokudla. Ukuthatha lo muthi nokudla kungashintsha inani elimuncwa ngumzimba futhi kubangele imiphumela emibi eyingozi.
- Phuza nengilazi yamanzi: Gwinya ikhaphu yonke nengilazi yamanzi.
- Ungaliphuli, ulichoboze, noma ulihlafune ikhaphu: Ungaliphuli, ulichoboze, noma ulihlafune ikhaphu.
- Uma unenkinga yokugwinya: Abanye abantu banenkinga yokugwinya ama-capsule. Uma kunjalo, ungakhathazeki. Vula i-capsule ngokucophelela, hlanganisa impuphu nethisipuni ye-applesauce, bese ugwinya ingxube ngokushesha . Ungayigcini ukuze isetshenziswe kamuva.
- Gwema i-grapefruit: Ungaphuzi ijusi ye-grapefruit noma udle i-grapefruit nganoma yisiphi isizathu. Kungashintsha ngendlela eyingozi indlela umuthi osebenza ngayo.
- Isikhathi sokusetshenziswa neminye imithi: Uma uthatha imithi ye-gastritis, ungayithathi imithi efana nemithi yokunciphisa i-acid (isb., i-Digene) zingakapheli amahora ama-2 ngaphambi noma ngemva kokuthatha le capsule. Thatha imithi efana ne-H2-blockers (isb., i-Famotidine) amahora ayi-10 ngaphambi noma amahora ama-2 ngemva kokuthatha le mithi. Cela udokotela wakho ukuthi akuqinisekise lokhu.
- Yithathe ngesikhathi: Zama ukuphuza imithi yakho ngesikhathi esifanayo nsuku zonke. Ungayeki ukuphuza imithi yakho ngaphandle kweseluleko sikadokotela wakho.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Uma uphuthelwe umthamo, ungalokothi uphinde kabili umthamo olandelayo ukuze ukhokhele. Lokho kungaba yingozi. Khohlwa umthamo ophuthelwe bese uthatha umthamo onqunyiwe kuphela ngesikhathi esilandelayo esihleliwe.
Kuthiwani uma ngiphuza umuthi omningi kakhulu?
Uma ngephutha uthatha umthamo ongaphezu konqunyiwe, kuyisimo esiphuthumayo. Shayela ngokushesha i-National Poisons Information Centre e-Colombo National Hospital , noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Eminye imithi engase ihlangane ne-Nilotinib
I-Nilotinib umuthi onamandla amakhulu okuxhumana neminye imithi. Ngakho-ke, kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo.
| Ungayithathi i-Nilotinib kanye nalo muthi. |
|---|
| I-Cisapride, i-Dronedarone, i-Pimozide, i-Thioridazine, i-Ziprasidone (imithi ethinta izinga lokushaya kwenhliziyo) |
| I-Flibanserin, i-Lomitapide, i-Saquinavir |
| I-Fluconazole, i-Posaconazole (elwa nesikhunta) |
| Uma usebenzisa lezi zinto, yazisa udokotela wakho. |
|---|
| Imithi yokulwa negciwane lengculazi |
| Ama-antibiotic afana ne-Clarithromycin ne-Erythromycin |
| Imithi yokucindezeleka kwegazi okuphezulu, isifo senhliziyo, kanye nesifo sengqondo |
| Ezinye izidakamizwa zokulwa ne-fungus ezifana ne-Ketoconazole, i-Itraconazole |
| Imithi yokwelapha i-gastritis (ama-antacid, i-cimetidine, i-omeprazole) |
| Izinto zokunciphisa igazi ezifana ne-Warfarin |
| Imikhiqizo yamakhambi njenge-St. John's Wort |
Akukho nolulodwa lwalezi hlu oluphelele. Ngakho-ke, kubalulekile ukuze uphephe ukutshela udokotela wakho ngayo yonke imithi, amavithamini, imikhiqizo yamakhambi, kanye nemithi yendabuko oyithathayo.
Yimiphi imiphumela emibi engaba khona yokuphuza umuthi?
Njenganoma yimuphi umuthi, i-Nilotinib ingabangela imiphumela emibi. Eminye iyingozi, kanti eminye ivamile. Into ebalulekile ukuqaphela lokhu futhi uthathe isinyathelo ngokushesha uma kudingeka.
| Umphumela ongemuhle | Izici ongazilindela |
|---|---|
| Imiphumela emibi edinga usizo lwezokwelapha ngokushesha | |
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe noma ulimi. |
| Ukopha | Indle emnyama noma enegazi, ukuhlanza okufana nekhofi eligayiwe, amabala abomvu esikhumbeni, ukuphuma kwegazi okungavamile ekhaleni noma ezinsinini. |
| Izinguquko ekushayeni kwenhliziyo | Ubuhlungu besifuba, isiyezi, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, ukuquleka. |
| Ukulimala kwesibindi | Umchamo ophuzi noma onsundu omnyama, ukuphuzi kwamehlo noma isikhumba, ubuhlungu engxenyeni engenhla kwesokudla yesisu, ukuphelelwa yisifiso sokudla. |
| I-Pancreatitis | Ubuhlungu besisu (ikakhulukazi obuphuma emhlane), ubuhlungu obuba bubi ngemva kokudla, umkhuhlane, isicanucanu, nokuhlanza. |
| Ukuqongelela koketshezi emzimbeni (i-Edema) | Ukukhuluphala okungazelelwe, ukuvuvukala kwamaqakala, izitho, nobunzima bokuphefumula. |
| Imiphumela emibi okufanele ibikwe kudokotela uma iqhubeka | |
| Izinkinga ezivamile | Ikhanda elibuhlungu, isicanucanu, ukuhlanza, isifo sohudo, ukuqunjelwa. |
Qaphela kakhulu ngesikhathi sokukhulelwa kanye nokuncelisa
Leli yiphuzu elibaluleke kakhulu.
- Ungalokothi ukhulelwe ngenkathi uthatha i-Nilotinib.
- Gwema ukukhulelwa okungenani izinsuku ezingu-14 ngemva kokuyeka imithi.
- Ungamncelisi umntwana wakho ibele ngesikhathi uthatha lo muthi futhi izinsuku ezingu-14 ngemva kokuyeka.
Lo muthi ungabangela umonakalo omkhulu enganeni engakazalwa, ngakho khuluma nodokotela wakho ngalokhu ngokukhululekile.
Umlayezo Wokuya Nawe Ekhaya
- Njalo thatha i-Nilotinib esiswini esingenalutho, kungaba ihora elilodwa ngaphambi noma amahora amabili ngemva kokudla.
- Ungalokothi udle i-grapefruit noma uphuze ujusi wayo.
- Qiniseka ukuthi utshela udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nemikhiqizo yamakhambi oyithathayo.
- Uma uhlangabezana nanoma yimiphi imiphumela emibi efana nobuhlungu besifuba, ubunzima bokuphefumula, noma ukopha okungavamile, funa iseluleko sezokwelapha ngokushesha.
- Gwema ukukhulelwa nokuncelisa ngokuphelele ngenkathi uthatha umuthi kanye nezinsuku ezingu-14 ngemva kokuyeka.
- Ungayeki ukuya emtholampilo wakho nodokotela. Yenza ukuhlolwa kwegazi lakho njengoba kuhleliwe.
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