Ngezinye izikhathi imisipha yethu izizwa sengathi ayinampilo, akunjalo? Amashiya ethu ayagoba, sinenkinga yokukhuluma nokugwinya, futhi amalungu ethu azizwa engaphilile. Namuhla sikhuluma ngomuthi okhethekile owelapha isimo esibizwa ngokuthi iMyasthenia Gravis, esinezimpawu ezinjengalezi. Lowo muthi yiPyridostigmine.
Iyini i-Pyridostigmine?
Kalula nje, i-Pyridostigmine iyisidakamizwa esisiza imisipha yakho ukuthi ithole amandla alahlekile. Imizwa nemisipha yomzimba wethu kuyaxhumana ngekhemikhali. Endabeni ye-'Myasthenia Gravis', lokhu kuxhumana kuyaphazamiseka. I-Pyridostigmine isebenza ngokunqoba lokho kuphazamiseka nokubuyisela ukuxhumana phakathi kwemizwa nemisipha.
Udokotela wakho angase akunike lo muthi ngaphansi kwamagama emikhiqizo efana neMestinon noma iMestinon Timespan. I-'Timespan' noma i-'extended-release' ibhekisela kuhlobo olumuncwa emzimbeni kancane futhi luhlale lusebenza isikhathi eside.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuthatha lo muthi
Kulungile, manje ngaphambi kokuqala lo muthi, kubaluleke kakhulu ukuthi udokotela wakho azi kahle ngesimo sakho sempilo. Uma unezinye zezimo zezokwelapha ezingezansi, qiniseka ukuthi uyamtshela ngazo.
| Isimo sezokwelapha/ezinye izindaba | Kungani kufanele unikeze ulwazi? |
|---|---|
| Isifuba somoya | I-Pyridostigmine inganciphisa kakhulu imigudu yokuphefumula futhi yandise ubunzima bokuphefumula. |
| Isifo senhliziyo noma ukushaya kwenhliziyo okuhamba kancane | Lo muthi ungase wehlise ijubane lokushaya kwenhliziyo. |
| Ubunzima noma ukuvinjelwa kokuchama | Lesi simo singase sibe sibi kakhulu. |
| Izilonda zesisu noma ukuvaleka kwamathumbu | Ubuhlungu besisu nezinye izinkinga zesisu zinganda. |
| Isifo sezinso | Njengoba umuthi ukhishwa emzimbeni yizinso, umthamo ungadinga ukulungiswa. |
| Ukutheleleka kwesisu (isb. i-Peritonitis) | Izimpawu zingaba zicashile futhi ukuxilongwa kungaba nzima. |
| Ukukhulelwa noma ukuzama ukukhulelwa | Udokotela uzonquma ukuthi ingane ithintekile yini. |
| Ukuncelisa | Kubalulekile ukucabangela ukuthi umuthi udluliselwa enganeni ngobisi lwebele yini. |
| Ukungezwani neminye imithi, ukudla noma izinto ezithile | Lokhu kubalulekile ukuhlola ingozi yokuba nomzimba ongezwani nomuthi. |
Ngingawusebenzisa kanjani lo muthi?
Khumbula la maphuzu uma usebenzisa lo muthi:
- Gwinya leli philisi lonke ngengilazi yamanzi.
- Ungaliphuli, ulichoboze, noma ulihlafune iphilisi, ikakhulukazi uma liwuhlobo 'lokukhululwa okunwetshiwe' (i-Timespan), njengoba lokhu kungabangela ukuthi umuthi ungene emzimbeni ngokushesha kakhulu futhi kubangele imiphumela emibi.
- Thatha umthamo oqondile, njengoba nje udokotela wakho emyalile. Udokotela wakho uzokutshela ukuthi kangaki ngosuku nokuthi kufanele uthathe malini.
- Ungalokothi uyeke ukuphuza imithi yakho ngokuzumayo ngaphandle kweseluleko sikadokotela wakho. Ukwenza kanjalo kungabangela izimpawu (isib. ubunzima bokugwinya, ubunzima bokuphefumula) zibe zimbi ngokuzumayo.
- Uma lo muthi unikezwa izingane, kudingeka ukunakekelwa okukhethekile futhi kufanele wenziwe kuphela ngokweseluleko sikadokotela.
Okubalulekile: Uma ucabanga ukuthi uthathe umthamo ongaphezu konconywayo, shayela udokotela wakho ngokushesha.Shayela i-National Poisons Information Centre e-Colombo National Hospital, noma uye e-Emergency Treatment Unit (ETU) yesibhedlela esiseduze.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Thatha umthamo ophuthelwe ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe. Ungathathi umthamo ophindwe kabili nganoma yisiphi isizathu!
Ezinye izinto ezingase zihlangane nalo muthi
Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi, amavithamini, kanye nezithasiselo zokudla ozithathile, njengoba i-Pyridostigmine ingasebenzisana neminye imithi.
| Uhlobo lokushayisana | Izibonelo (izinhlobo zemithi) |
|---|---|
| Ungayithathi i-Pyridostigmine kanye nalo muthi. | |
| Ngenxa yokuthi izenzo ziyafana, imiphumela emibi inganda. | Eminye imithi ye-myasthenia gravis (isb. i-neostigmine), i-quinine. |
| Sicela wazise udokotela wakho ngoba lokhu kungase kuthinte imithi yakho. | |
| I-Pyridostigmine inganciphisa noma yandise ukusebenza kwayo noma ibangele imiphumela emibi. | i-atropine, i-bethanechol, i-disopyramide, i-edrophonium, i-guanethidine, i-mecamylamine, kanye neminye imithi elawula ubuhlungu bemisipha noma bemizwa. |
Lolu hlu aluphelele, ngakho-ke kungcono ukutshela udokotela wakho nganoma yini oyithathayo.
Izinto okufanele uzikhumbule lapho uthatha imithi
- Bona udokotela wakho ngesikhathi esihleliwe ukuze uhlole isimo sakho. Uma izimpawu zakho ziqhubeka noma ziba zimbi kakhulu, tshela udokotela wakho.
- Kubaluleke kakhulu ukuphatha umazisi wezokwelapha othi une-Myasthenia Gravis kanye nemithi oyiphuzayo kanye nemithamo yayo. Lokhu kungaba usizo kakhulu esimweni esiphuthumayo.
Yimiphi imiphumela emibi engaba khona?
Njenganoma yimuphi umuthi, i-Pyridostigmine ingabangela eminye imiphumela emibi. Kodwa-ke, akuwona wonke umuntu oyitholayo. Ake sibheke ukuthi iyini le miphumela.
| Umphumela ongemuhle | Okufanele ngikwenze |
|---|---|
| Uma kwenzeka noma yikuphi kwalokhu, tshela udokotela wakho ngokushesha. | |
| Ukusabela kokungezwani komzimba (ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso/izindebe/ulimi) | Funa iseluleko sezokwelapha ngokushesha. |
| Ubunzima bokuphefumula | |
| Izinguquko zombono | |
| Ubuhlungu obukhulu bemisipha, ukuqaqamba, noma ukuxhuga | |
| Ukushaya kwenhliziyo okuhamba kancane kakhulu noma okungajwayelekile | |
| Ubuhlungu obukhulu besisu, ukuhlanza | |
| Ukukhathala noma ubuthakathaka obungavamile | |
| Lokhu ngokuvamile akulona ingozi, kodwa uma kuqhubeka, tshela udokotela wakho. | |
| Uhudo (ikakhulukazi ekuqaleni kokwelashwa) | Uma isimo siqhubeka, yazisa udokotela. |
| Ukuthelwa amathe ngokweqile | |
| Ukujuluka okukhulu, isicanucanu | |
Kufanele uwugcine kanjani umuthi wakho?
- Yigcine endaweni ephephile kude nezingane.
- Gcina ekamelweni lokushisa (phakathi kuka-15-30 Celsius). Vikela ekushiseni okukhulu noma ekubandeni.
- Vikela emswakama kanye naselangeni eliqondile. Gcina ibhodlela lemithi livaliwe kahle.
- Lahla imithi ephelelwe yisikhathi ngaphandle kokuyisebenzisa.
Umlayezo Wokuya Nawe Ekhaya
- I-Pyridostigmine umuthi osetshenziselwa ukwelapha isifo sobuthakathaka bemisipha i-Myasthenia Gravis.
- Ngaphambi kokuqala lo muthi, tshela udokotela wakho ngazo zonke ezinye izimo zezokwelapha onazo (ikakhulukazi i-asthma, isifo senhliziyo, isifo sezinso).
- Gwinya iphilisi lonke, ngaphandle kokuliphula noma ukulichoboza. Lithathe ngesikhathi esinqunyiwe.
- Ungayeki ukuthatha imithi ngokuzumayo ngaphandle kweseluleko sikadokotela wakho.
- Uma uhlangabezana nanoma yimiphi imiphumela emibi kakhulu, njengobunzima bokuphefumula, ubuhlungu obukhulu bemisipha, noma ukushaya kwenhliziyo okuhamba kancane, xhumana nodokotela wakho ngokushesha.
- Tshela udokotela wakho ngayo yonke eminye imithi oyithathayo. Lokhu kubaluleke kakhulu ukuze uphephe.
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
💬 Isetshenziselwani i-Pyridostigmine / Mestinon?
Leli iphilisi elibaluleke kakhulu neliyinhloko elinikezwa isifo esibi kakhulu semisipha ebizwa ngokuthi 'iMyasthenia Gravis'! Lapho izimpawu ezivela ebuchosheni bethu ziyeka ukufinyelela emisipheni, imisipha yethu iyakhubazeka (asikwazi ukuvula amehlo ethu, ukukhuluma, noma ukuhamba). Lokho okwenziwa yileli philisi ukubuyisela amandla aleyo misipha elahlekayo nokubuyisela isiguli esimweni esijwayelekile.
💬 Lo muthi (i-Pyridostigmine / i-Mestinon) uvuselela kanjani imisipha?
Umyalezo oya emisipheni uthunyelwa usuka ebuchosheni bethu ngemizwa yikhemikhali ebizwa ngokuthi 'i-Acetylcholine'. Kodwa ezigulini ezine-Myasthenia, lezi zibhujiswa ngokushesha (yi-enzyme ye-Cholinesterase). Ngemva kokuthatha lo muthi, i-enzyme ebhubhisayo iyavinjelwa (i-Cholinesterase inhibitor), bese i-acetylcholine eningi ivunyelwa ukuthi iqoqeke eduze kwemisipha. Ngemuva kwalokho imisipha ingasebenza/inciphe ngokujwayelekile/ngokuqinile futhi.
💬 Yimiphi imiphumela emibi ecasulayo engenzeka uma uthatha lo muthi?
Lokhu akugcini nje ngokuvuselela imisipha, kodwa futhi kwandisa kakhulu umsebenzi wezitho zangaphakathi njengamathumbu/isinyi! Ngakho-ke, ukuphuza lokhu kungabangela imiphumela emibi ecasulayo njengokuthi 'uhudo olunzima, ubuhlungu obukhulu besisu, ukuqunjelwa/ukuklebhuka emlonyeni/emehlweni, kanye nokuchama njalo'. (Futhi, uma umthamo ukhushulwa, imisipha ingase iwele/ingasebenzi!)
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