Uma unesifo sikashukela sohlobo 2, cishe usuvele uthatha imithi efana ne-Metformin. Kodwa udokotela wakho kungenzeka ukuthi ukutshelile ngemithi emisha ebizwa ngokuthi ama-SGLT2 inhibitors. Noma kungenzeka ukuthi uke wezwa ngayo. Ngakho-ke, iyini ama-SGLT2 inhibitors? Asebenza kanjani ngempela? Kulesi sihloko, sizokhuluma ngayo kalula nangokunembile.
Ziyini lezi zithiyo ze-SGLT2?
Kalula nje, ama-inhibitor e-SGLT2 uhlobo lwephilisi eliphuzwayo elisiza ukulawula amazinga kashukela egazini lakho. Into ngazo ukuthi zisebenza ngendlela ehlukile kancane kuneminye imithi yesifo sikashukela.
Cabanga ngakho, izinso zethu ziyisimiso sokuhlunga esimangalisayo. Lapho sihlanza igazi lethu, izinso zihlunga ushukela othile (i-glucose) egazini lethu ziwufake emchameni wethu. Kodwa-ke, izinso zethu zineprotheni ebizwa ngokuthi i-Sodium-glucose cotransporter 2 , noma i-SGLT2 ngamafuphi. Njengomgcini wesango, le phrotheni ye-SGLT2 ibamba iningi loshukela eliya emchameni bese liwubuyisela egazini.
Uyaqonda manje? Umuntu onesifo sikashukela usevele unoshukela ophezulu egazini. Ngakho-ke lokho okwenziwa yilaba bavimbeli be-SGLT2 ukuthi bacime lowo mlindi wesango, iphrotheni ye-SGLT2, kancane. Ngemuva kwalokho ayikwazi ukubuyisa ushukela bese iwufaka egazini. Ngenxa yalokho, ushukela omningi ukhishwa emzimbeni ngomchamo . Le yindlela le mithi ehlisa ngayo amazinga kashukela egazini lakho.
Lolu hlobo lomuthi luhlukile ngoba lwehlisa ushukela egazini ngendlela ehlukile, ngaphandle kokuthinta ngqo i-hormone insulin.
Yiziphi izithibi ze-SGLT2 ezivame kakhulu eSri Lanka nakwamanye amazwe?
Kunezinhlobo eziningana zemithi kuleli qembu. Yonke yenza into efanayo. Ivame ukuthathwa kanye ngosuku, ngaphambi kokudla kokuqala kosuku. Udokotela wakho uzohlola isimo sakho futhi akunike imithi efanele kakhulu.
| Igama elijwayelekile lomuthi | Igama lomkhiqizo elisetshenziswa kakhulu |
|---|---|
| I-Canagliflozin | I-Invokana |
| I-Dapagliflozin | I-Farxiga |
| I-Empagliflozin | I-Jardiance |
| I-Ertugliflozin | I-Steglatro |
| I-Bexagliflozin | I-Brenzavvy |
Ubani ofanele ukusebenzisa lo muthi?
Lona umbuzo obaluleke kakhulu. Ama-inhibitor e-SGLT2 akuwona umuthi wokuqala udokotela angawunikeza isifo sikashukela sohlobo lwesibili.
Ngokuvamile, udokotela uzoqala akweluleke ngokushintsha indlela yokuphila , njengokulawula ukudla kanye nokuzivocavoca, bese eqala umuthi ofana ne-Metformin.
Udokotela wakho angase acabangele i-SGLT2 inhibitor ezimweni ezilandelayo:
- Usuvele uthatha imithi eminingana, kodwa ushukela wakho wegazi awukalawulwa kahle .
- Uma unesizathu sezokwelapha sokuthi kungani ungenakukwazi ukuthatha eminye imithi yesifo sikashukela.
- Uma usengozini yokuba noshukela wegazi ophansi kakhulu (hypoglycemia).
- Uma udinga ukwehlisa isisindo noma ukwehlisa umfutho wegazi.
Ubani okungafanele athathe lo muthi?
Lolu hlobo lomuthi alufanele wonke umuntu.
- Lo muthi awuvunyelwe kubantu abanesifo sikashukela sohlobo 1 .
- Lokhu akukhuthazwa kubantu abake baba nenkinga enkulu yesifo sikashukela ebizwa ngokuthi i-diabetic ketoacidosis .
- Lo muthi ngeke ube usizo olukhulu kumuntu osevele ehlushwa isifo sezinso esibi .
- Uma ukhulelwe, uzama ukukhulelwa, noma uncelisa, kufanele nakanjani ukhulume nodokotela wakho mayelana nokusebenzisa lo muthi. Ayikho idatha eyanele ngokuphepha kwawo okwamanje. Ngakho-ke, ungaqali noma uyeke ukuthatha lo muthi ngaphandle kokubonisana nodokotela.
Yimiphi imiphumela emibi engaba khona?
Njenganoma yimuphi umuthi, lo muthi ungabangela imiphumela emibi. Kodwa-ke, akuwona wonke umuntu oyitholayo. Futhi eminingi yayo ingalawulwa.
| Umphumela ongemuhle | Incazelo kanye nalokho okufanele ukwazi |
|---|---|
| Ukuchama njalo kanye nokoma | Ngenxa yokuthi ushukela ukhishwa emchameni, kungadingeka ukuthi uchame njalo emini nasebusuku. Lokhu kungandisa ukoma kwakho. Phuza amanzi amaningi. |
| Ukutheleleka komgudu womchamo kanye nobulili | Ushukela osemchameni wandisa ingozi yemvubelo kanye nokutheleleka ngamagciwane. Tshela udokotela wakho uma uhlangabezana nezimpawu ezifana nokulunywa, ukuvuvukala, noma ubuhlungu endaweni yesitho sangasese sowesifazane. |
| Ukwehlisa isisindo | Ungase wehlise isisindo ngoba ushukela (amakhalori) ukhishwa emchameni. Lokhu kuyinzuzo kwabanye abantu. |
| Umfutho wegazi ophansi kanye nokuphelelwa amanzi emzimbeni | Ngezinye izikhathi, njengoba uketshezi lukhishwa emzimbeni, umfutho wegazi ungehla, okungakwenza uzizwe ukhathele futhi unesiyezi. |
| Umphumela omubi kakhulu odinga ukunakekelwa okusheshayo | |
| I-Diabetic Ketoacidosis (DKA) | Lesi yisimo esingavamile kodwa esiyingozi kakhulu . Umzimba ushisa amafutha esikhundleni sikashukela, ukhiqiza ama-acid abizwa ngokuthi ama-ketone. Uma uzwa izimpawu ezifana nokucanuzela kwenhliziyo, ukuhlanza, ubuhlungu obukhulu besisu, ukukhathala okukhulu, kanye nobunzima bokuphefumula, tshela udokotela wakho ngokushesha noma uye egumbini lezimo eziphuthumayo esibhedlela esiseduze (i-ETU). |
Akukhona nje kuphela isifo sikashukela, kunezinye izinzuzo!
Nakuba lo muthi ekuqaleni waklanywa ukwelapha isifo sikashukela, ucwaningo luthole ukuthi unezinye izinzuzo eziningana ezimangalisayo.
1. Ukuvikela izinso: Le mithi inganciphisa umonakalo ezinso obangelwa isifo sikashukela futhi ilawule ukuqhubeka kwesifo sezinso esingamahlalakhona.
2. Ukunciphisa ingozi yokuhlaselwa yinhliziyo nokufa ngenxa yokuhlaselwa yinhliziyo: Amanye ama-inhibitor e-SGLT2 aboniswe ukuthi anciphisa ingozi yokulaliswa esibhedlela nokufa, ikakhulukazi uma enikezwa iziguli ezinesifo senhliziyo.
3. Ukunciphisa ingozi yokuhlaselwa yinhliziyo kanye nesifo sohlangothi: Ezinye izifundo zikhombisile ukuthi lokhu nakho kunegalelo ekunciphiseni ingozi yokuhlaselwa yinhliziyo kanye nesifo sohlangothi.
Ngenxa yalezi zizathu, odokotela ngezinye izikhathi bangase banikeze lo muthi kubantu abangenaso isifo sikashukela kodwa abanesifo sezinso noma senhliziyo.
Umlayezo Wokuya Nawe Ekhaya
- Ama-inhibitor e-SGLT2 ayiqembu elisha lemithi ephuzwayo elapha isifo sikashukela sohlobo lwesibili.
- Lokhu kusebenza ngokuvimbela izinso ukuthi zingamunci ushukela egazini futhi ziwukhiphe emchameni.
- Lena ngokuvamile akuyona imithi yokuqala enikezwa isifo sikashukela. Udokotela wakho angase ayincome uma ushukela wegazi lakho ungalawulwa ngezinye izindlela zokwelapha.
- Ngaphezu kokulawula isifo sikashukela, zinekhono elimangalisayo lokuvikela izinso nokunciphisa ingozi yesifo senhliziyo.
- Njenganoma yimuphi umuthi, kungaba nemiphumela emibi. Khuluma nodokotela wakho nganoma yiziphi izinguquko ozizwayo.
- Udokotela wakho kuphela onganquma ukuthi lo muthi ukulungele yini, ngakho qiniseka ukuthi uxoxa naye ngalokhu.
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