Ingabe ngezinye izikhathi uzizwa uphelelwa umoya, noma ukhathele kancane uma uhamba? Noma uzizwa usinda esifubeni sakho futhi ukhathele kancane uma inhliziyo yakho ishaya? Lokhu kungaba ngenxa yezizathu eziningana. Kodwa-ke, ngezinye izikhathi imbangela yalokhu kumane nje ukwanda komfutho wegazi emithanjeni yegazi emaphashini akho. Odokotela babiza lesi simo ngokuthi 'i-Pulmonary Arterial Hypertension' (PAH). Ezimweni ezinjalo, umjovo okhethekile odokotela abawusebenzisayo ukukusiza ubizwa ngokuthi i-Sildenafil Injection. Ake sixoxe ngalomuthi ngokuningiliziwe namuhla, akunjalo?
Kwenzekani ngempela ngalo muthi obizwa ngokuthi i-Sildenafil Injection?
Kalula nje, i-Sildenafil umuthi onikezwa abantu abane-pulmonary arterial hypertension (PAH). Manje cabanga ukuthi imithambo yegazi emincane emaphashini akho ifana namapayipi athwala amanzi. Kulesi simo se-PAH, okwenzekayo ukuthi leyo mithambo yegazi iba mincane futhi iqine. Ngemuva kwalokho inhliziyo kufanele isebenze kanzima ukupompa igazi ngale mithambo emincane iye emaphashini. Kufana nokusunduza amanzi ngepayipi elivalekile ephampini lamanzi. Lokhu kwenza inhliziyo ikhathale, kwenza kube nzima ukuphefumula, futhi kukwenze uzizwe ukhathele ngokushesha.
Yilapho i-Sildenafil ingena khona. Lo muthi usebenza ngokukhulula imithambo yegazi emincane emaphashini akho. Okusho ukuthi, uyawandisa kancane. Lokhu kuvumela igazi ukuthi ligeleze kuwo kalula. Kuphinde kunciphise ingcindezi emaphashini akho. Lokhu kwenza kube lula ngenhliziyo yakho ukupompa igazi, kwenza kube lula ukuphefumula, futhi kukunika amandla okunyakaza kancane. Kungenzeka ukuthi uke wezwa ngalo muthi onegama lomkhiqizo elithi `(Revatio)`.
Yiziphi izinto okudingeka uzitshele udokotela wakho ngaphambi kokusebenzisa lo muthi?
Lokhu kubaluleke kakhulu. Ngaphambi kokuba unikezwe umjovo we-Sildenafil, ithimba lakho lezokwelapha, okuhlanganisa odokotela nabahlengikazi, kufanele liqaphele lezi zinto. Ngoba ezinye izimo zempilo zingase zingahambisani nalo muthi noma zingadinga ukunakekelwa okukhethekile.
Uma unezinye zalezi zinto, qiniseka ukuthi usitshela:
- Uma unokukhubazeka kokuzalwa kwepenis yakho, noma isimo esifana nesifo sikaPeyronie.
- Wake wabhekana nesimo esibizwa ngokuthi i-priapism, okuwukuvuka okubuhlungu kwepenis isikhathi eside ngaphandle kwesizathu?
- Uma unezinkinga zokopha.
- Uma unesifo samehlo noma unenkinga yokubona.
- Uma unesifo senhliziyo (isib. izinkinga ze-valve yenhliziyo, ukuhlaselwa yinhliziyo).
- Uma umfutho wegazi lakho, okungukuthi, umfutho wegazi, uphezulu kakhulu noma uphansi kakhulu.
- Uma uke waba nesifo esihlobene negazi, isibonelo, i-sickle cell anemia noma i-leukemia.
- Uma unesifo sezinso.
- Uma unesifo sesibindi.
- Uma unesifo esibizwa ngokuthi isifo se-pulmonary veno-occlusive (PVOD).
- Uma unesilonda esiswini.
- Uma une-allergy ku-Sildenafil, noma yimuphi omunye umuthi, ukudla, amadayi, izithasiselo, noma yini enye, okungukuthi, uma une-allergy.
- Uma ukhulelwe noma ulindele umntwana, lokhu kuyinto okufanele uyisho nakanjani.
- Uma ungumama oncelisayo, yazisa udokotela wakho ngalokhu futhi.
Kuphela uma ukhuluma lezi zinto ngokwethembeka futhi ungafihli lapho uzokwazi ukuthola ukwelashwa ngokuphephile.
Uyisebenzisa kanjani le mithi?
I-Sildenafil umuthi onikezwa njengomjovo emthanjeni. Lokhu akuyona into ongayithatha ekhaya. Inikezwa esibhedlela noma emtholampilo, ngaphansi kokuqashwa kwezokwelapha.
Okubalulekile: Lo muthi awuvunyelwe ukusetshenziswa ezinganeni ezincane. Ngakho-ke, khuluma nodokotela wakho mayelana nokuwusebenzisa ezinganeni.
Yini okufanele uyenze uma uthatha umuthi omningi kakhulu (ukudlula umthamo)?
Uma ucabanga ukuthi usuthathe lo muthi omningi kakhulu, noma uphuze ngokweqile ngengozi, shayela i-Poison Control Center noma igumbi lezimo eziphuthumayo esibhedlela esiseduze ngokushesha.
Okunye: Lo muthi unikezwe wena wedwa. Ungabelani ngalo muthi nanoma ubani nganoma yisiphi isizathu . Impilo yawo wonke umuntu ihlukile, ngakho-ke okusebenzela wena kungase kungasebenzi komunye umuntu, futhi kungaba yingozi.
Kuthiwani uma ngiphuthelwa umthamo wemithi?
Njengoba lo muthi uvame ukunikezwa esibhedlela, akunakwenzeka ukuthi uzophuthelwa umthamo. Kodwa-ke, uma ngesizathu esithile ungakwazi ukuthatha umuthi wakho ngesikhathi, yazisa ithimba lakho lezempilo ngokushesha. Bazokutshela ukuthi wenzeni ngokulandelayo.
Yimiphi eminye imithi okungafanele isetshenziswe nalo muthi (ingase ihlangane)?
Lokhu futhi kuyinto okufanele uyiqaphele kakhulu. Kuneminye imithi engabangela imiphumela emibi eyingozi uma ithathwa nge-Sildenafil. Ngakho-ke, uma uthatha noma yimuphi wale mithi elandelayo, ungayithathi i-Sildenafil:
- I-Cisapride
- I-Cobicist
- Ama-Nitrate - Izibonelo zifaka phakathi i-amyl nitrite, i-isosorbide dinitrate, i-isosorbide mononitrate, kanye ne-nitroglycerin. Lawa avame ukusetshenziswa ukwelapha ubuhlungu besifuba (i-angina).
- I-Riociguat
- I-Telaprevir
Ngaphezu kwalokho, kuneminye imithi engasebenzisana ne-Sildenafil, okusho ukuthi ingaphazamisana nayo. Lokhu kufaka phakathi:
- Eminye imithi yokulwa namagciwane ye-HIV noma i-AIDS
- I-Bosentan
- Eminye imithi ye-Benign Prostatic Hyperplasia (BPH)
- Eminye imithi esetshenziswa ukulawula umfutho wegazi
- Eminye imithi yokwelapha izifo zesikhunta - isibonelo i-Ketoconazole, i-Itraconazole
- I-Cimetidine
- I-Erythromycin
- I-Rifampin
Lolu hlu aluphelele. Ngakho-ke, tshela udokotela wakho ngayo yonke imithi oyithathayo (eyalelwe udokotela wakho, ngaphandle kwemithi kadokotela), okuhlanganisa imithi yamakhambi, amakhambi, kanye nezithasiselo zokudla, kanye nokuthi ubhema, uphuza utshwala, noma usebenzisa ezinye izidakamizwa ezingekho emthethweni. Ezinye zalezi zingase zihlangane nalo muthi.
Yini okufanele ngiyiqaphele lapho ngithatha lo muthi?
Qaphela noma yiziphi izinguquko emzimbeni wakho ngenkathi uthatha i-Sildenafil.
- Uma izimpawu zakho (isib. ukuphelelwa umoya, ukukhathala) zingathuthuki nhlobo, noma zibonakala ziba zimbi kakhulu, tshela ithimba lakho lezokwelapha.
- Uma uqaphela ngokuzumayo noma yiziphi izinguquko ekuboneni kwakho noma ekuzweni, tshela udokotela wakho ngokushesha.
- Ungase uzizwe unesiyezi lapho uthatha lo muthi. Ngakho-ke, gwema ukushayela, ukusebenzisa imishini, noma ukwenza noma yini edinga ukuqapha uze wazi kahle ukuthi lo muthi uthinta kanjani wena.
- Ungasukumi uhleli ngokuzumayo, noma uhlale phansi umi ngokuzumayo. Qaphela kakhulu uma usukhulile. Lokhu kunganciphisa ingozi yokuba nesiyezi nokuwa.
- Gwema ukuphuza utshwala. Utshwala bungenza isiyezi sibe sibi nakakhulu.
Yimiphi imiphumela emibi engaba khona yalo muthi?
Njenganoma yimuphi umuthi, i-Sildenafil ingabangela eminye imiphumela emibi. Akuwona wonke umuntu oyitholayo, kodwa kuhle ukuqaphela.
Imiphumela emibi okufanele utshele udokotela wakho ngayo ngokushesha:
Uma uhlangabezana nanoma yiziphi zalezi zimpawu, kufanele ufune iseluleko sezokwelapha ngokushesha:
- Ukusabela kokungezwani komzimba: Ukuqubuka kwesikhumba, ukuqubuka, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi kanye nomphimbo.
- Ukulahlekelwa ukuzwa noma ukukhala ezindlebeni.
- Izimpawu zokuhlaselwa yinhliziyo: Ubuhlungu noma ukuqina kwesifuba, ubuhlungu obuphuma emahlombe, ezingalweni, noma emhlathini, isicanucanu, ubunzima bokuphefumula, ukujuluka okubandayo, kanye nokuquleka.
- Ukushintsha kwesigqi senhliziyo: Ukuzizwa sengathi inhliziyo yakho ishaya ngokushesha noma ngokungajwayelekile, isiyezi, ukuquleka, ubuhlungu besifuba, ubunzima bokuphefumula.
- Umfutho wegazi ophansi: isiyezi, ukuquleka, ukubona okufiphele.
- Ukuphefumula okusha noma okubi kakhulu.
- Ukuma isikhathi eside noma ubuhlungu.
- Izimpawu zesifo sohlangothi: Ukungazweli noma ubuthakathaka bobuso, ingalo, noma umlenze (ikakhulukazi ohlangothini olulodwa lomzimba), ubunzima bokukhuluma, ukudideka, ubunzima bokuhamba, ukulahlekelwa yibhalansi, isiyezi, ikhanda elibuhlungu kakhulu, izinguquko embonweni.
- Ukulahlekelwa umbono ngokuzumayo kwelinye noma kuwo womabili amehlo.
Imiphumela emibi evame ukungabi yingozi, kodwa okufanele ibikwe kudokotela wakho uma iqhubeka:
Lezi zinto ngokuvamile azizimbi kangako, kodwa uma ziqhubeka noma zikukhathaza, tshela udokotela wakho ngazo:
- Ukushawa kobuso noma ukubomvu
- Ikhanda elibuhlungu
- Ukopha ekhaleni
- Impumulo egobhozayo noma evalekile, njengomkhuhlane
- Inkinga yokulala
- Isisu esibuhlungu, uzizwa sengathi unesifo sokungagayi kahle ukudla
Lolu hlu aluhlanganisi yonke imiphumela emibi engaba khona. Uma ubona noma yini engavamile ngaphezu kwale, buza udokotela wakho ngayo.
Uwugcina kanjani umuthi?
Njengoba lo mjovo we-Sildenafil unikezwa esibhedlela noma emtholampilo, akudingeki uwuyise ekhaya. Ngakho akudingeki ukhathazeke ngokugcina umuthi.
Umlayezo Wokuya Nawe Ekhaya
Kulungile, ake sikhumbule amaphuzu abaluleke kakhulu kulokho esikhulume ngakho.
- Umjovo we-Sildenafil umuthi ofakwa ngemithambo ophatha ngokuyinhloko umfutho wegazi ophakeme we-pulmonary arterial (PAH).
- Lokhu kukhulula imithambo yegazi emaphashini, okwenza kube lula ngenhliziyo ukupompa igazi, futhi kuthuthukise ukuphefumula.
- Kufanele nakanjani utshele udokotela wakho nganoma yiziphi ezinye izifo onazo, eminye imithi oyithathayo, kanye nanoma yikuphi ukungezwani komzimba onakho.
- Lo muthi unikezwa esibhedlela noma emtholampilo. Awuvunyelwe ezinganeni ezincane.
- Kuyingozi kakhulu ukuthatha lokhu kanye neminye imithi (ikakhulukazi ama-nitrate).
- Qaphela izinto ezifana nesiyezi kanye nokushintsha kombono. Uma uhlangabezana nanoma yimiphi imiphumela emibi, tshela udokotela wakho ngokushesha.
- Lomuthi ungowakho wedwa. Ungawuniki omunye umuntu.
Ngiyethemba ukuthi lolu lwazi luzokusiza. Uma uneminye imibuzo, ungangabazi ukubuza udokotela wakho noma usokhemisi. Bazokusiza. Hlala uphilile!
👩🏽⚕️ Imibuzo eyengeziwe (ama-FAQ)
💬 Ingabe i-Atovaquone ne-Proguanil (Atovaquone; Proguanil / Malarone) ziyiphilisi likamalaleveva?
Yebo! Leli yiphilisi likamalariya 'elingcono kakhulu neliphephile' emhlabeni! Labo abaya emazweni afana ne-Afrika ne-India lapho omiyane bakamalariya baningi khona banikezwa inhlanganisela yale mithi emibili ukuvimbela umalaleveva (Ukuvimbela / Ukuvimbela), kanti labo asebevele bengenwe umalaleveva banikezwa inhlanganisela yale mithi emibili ukuze bayelaphe ngokuphelele (Ukwelashwa).
💬 Le mithi emibili isebenza kanjani ndawonye ukubulala igciwane le-malaria egazini lethu?
Lokhu kuhlasela i-parasite kusuka ezinhlangothini ezimbili! I-Atovaquone ivala ngokuphelele izimboni zokuphefumula/ukukhiqiza amandla ze-parasite ye-malaria (i-Mitochondria). Ngakolunye uhlangothi, i-Proguanil iyayimisa 'ukukhiqizwa kwe-DNA' ye-parasite (ukwenziwa kwe-Folic acid). Uma lokhu kokubili kwenzeka ndawonye, i-parasite ye-malaria enzima iyafa ngokushesha, ayikwazi ukusinda.
💬 Yimiphi imiphumela emibi eyinhloko yokuphuza la maphilisi e-malaria (i-Malarone)?
Leli philisi liphephile kakhulu (alibangeli ukucasuka kwamehlo/ukuphazamiseka kwengqondo njenge-Chloroquine yangaphambilini). Kodwa-ke, ukuthatha lokhu kungabangela 'ubuhlungu besisu, ukuhlanza okukhulu kanye nesifo sohudo' (ukuphazamiseka kwe-GI). Ngakho-ke, leli philisi kufanele lithathwe 'nokudla okuhle noma ingilazi yobisi/okuthile okunamafutha' (yilapho limuncwa kahle ngumzimba). Ungase futhi ubhekane namaphupho angajwayelekile.
i- sildenafil, umfutho wegazi ophezulu we-pulmonary arterial, i-revatio, umfutho wegazi ophezulu we-pulmonary arterial, impilo yenhliziyo, imiphumela emibi, umjovo
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