Wo LDH dodow yɛ dɛn? (LDH - Lactate Dehydrogenase Test) Momma yɛnhwehwɛ eyi ho asɛm kɛkɛ!

Ɛnnɛ yɛrebɛka sɔhwɛ bi a ɛbɛtumi akyerɛ yɛn nsɛm a ɛho hia pii afa yɛn nipadua akwahosan ho. Ebia woate `LDH` sɔhwɛ no ho asɛm. Ebia oduruyɛfo bi mpo aka akyerɛ wo sɛ yɛ nhwehwɛmu yi. Enti, momma yɛnhwɛ nea saa `LDH` yi yɛ ne nea wubetumi asua afi sɔhwɛ yi mu tiawa.

Dɛn ne lactate dehydrogenase (LDH)?

Enti, nea edi kan no ma yɛnhwɛ nea `Lactate Dehydrogenase` yɛ. Yɛsan frɛ no `(LDH)` tiawa. Sɛ yɛbɛka no tiawa a, eyi yɛ enzyme a ɛho hia paa wɔ yɛn nipadua mu. Enzyme yɛ protein bi a ɛma nnuru yɛ adwuma ntɛmntɛm na ɛboa wɔ yɛn nipadua mu. Fa no sɛ aboafo nketewa a ɛma yɛn nipadua yɛ adwuma yɛ mmerɛw.

Saa `LDH` enzyme yi boa titiriw wɔ yɛn nkwammoaa mu home mu . Ɛne sɛ, saa `LDH` yi boa wɔ adeyɛ a ɛho hia yiye a ɛne sɛ yɛbɛfa glucose (sɛ yɛbɛka no tiawa a, asikre) a ɛwɔ aduan a yedi mu na yɛanya ahoɔden a yɛn nipadua mu nkwammoaa hia no. Eyi te sɛ nea yɛboa ma nkwammoaa a ɛyɛ adwuma te sɛ anyinam ahoɔden mfiri nketewa a ɛwɔ yɛn nipadua mu no yɛ pɛtro.

So wunim sɛ ɛkame ayɛ sɛ saa enzyme `LDH` yi wɔ yɛn nipadua mu ntini biara mu? Nanso ɛdɔɔso sen biara wɔ ntini, mmerɛbo, asaabo, ne mogya mu nkwammoaa kɔkɔɔ mu . Sɛ nkwammoaa foforo ba yɛn nipadua mu a, woyi nkwammoaa dedaw anaa "awuwu" fi hɔ. Eyi yɛ ade a ɛfata. Sɛ woyi nkwammoaa dedaw a, wɔde `LDH` bi a efi saa ntini no mu ka yɛn mogya anaa nipadua mu nsu afoforo ho. Enti, ɛyɛ ade a ɛfata sɛ wobenya `LDH` bi wɔ mogya anaa nipadua mu nsu foforo mu.

Enti, dɛn ne saa LDH (lactate dehydrogenase) sɔhwɛ yi?

Okay, seesei wowɔ adwene kakra wɔ nea `LDH` yɛ ho. `LDH` sɔhwɛ susuw `LDH` dodow a ɛwɔ wo mogya anaa nipadua mu nsu afoforo mu. Ɛhwɛ titiriw sɛ wo nipadua no ntini asɛe anaa .

Sɛnea yɛadi kan aka ho asɛm no, ɛyɛ ade a ɛfata sɛ `LDH` dodow bi bɛba wo mogya mu. Nanso, sɛ wo nipadua mu ntini biara asɛe anaasɛ apira a , `LDH` a ɛboro so a efi saa ntini a asɛe no mu no bɛkɔ wo mogya anaa nipadua mu nsu afoforo mu. Enti, sɛ wo `LDH` dodow korɔn sen sɛnea ɛte daa a, ebetumi akyerɛ sɛ ntini bi a ɛwɔ wo nipadua mu no asɛe esiane yare a enni sabea , yare a emu yɛ den , anaa opira bi nti .

Nanso adeɛ baako a ɛsɛ sɛ yɛkae ne sɛ ɛyɛ den sɛ yɛbɛhunu ntini pɔtee a `LDH` sɔhwɛ no nko ara sɛe . Efisɛ `LDH` wɔ mmeae pii wɔ yɛn nipadua mu. Enti, nnuruyɛfo taa hyɛ sɛ wɔnyɛ nhwehwɛmu afoforo pii ka `LDH` nhwehwɛmu no ho na ama wɔahu yare no pɛpɛɛpɛ.

Wɔde din afoforo pii nso frɛ saa `LDH` sɔhwɛ yi:

• `LD` sɔhwɛ
• Lactic dehydrogenase a wɔde hyɛ nipadua mu
• Lactic acid dehydrogenase a ɛwɔ nipadua no mu

Bere bɛn na ɛsɛ sɛ meyɛ LDH nhwehwɛmu?

Nnuruyɛfo de LDH nhwehwɛmu no di dwuma de hu akwahosan tebea ahorow na wɔhwɛ so. Nneɛma titiriw nti a wɔyɛ sɔhwɛ yi ne:

• Hwɛ sɛ wo nipadua mu ntini ahorow asɛe anaa .
• Hwɛ nyarewa te sɛ mogya a ɛtɔ kɔ nipadua mu , nyarewa a ɛwɔ akwaa a ɛwɔ nipadua no mu (sɛ nhwɛso no, mmerɛbo, asaabo), ne tebea horow a ɛsɛe ntini, te sɛ ɔyare mmoawa bi .
• Hwɛ sɛnea kokoram ahorow bi mu yɛ den .
• Hwɛ sɛ ebia kokoram ahorow bi ayaresa (e.g. nnuru a wɔde sa yare) no di yiye anaasɛ ɛnte saa.

Esiane sɛ wɔyɛ `LDH` sɔhwɛ no wɔ tebea ahorow pii mu nti, sɛ wɔaka akyerɛ wo sɛ yɛ nhwehwɛmu yi a, ɛyɛ papa sɛ wubebisa wo duruyɛfo nea enti a wɔreyɛ wo nhwehwɛmu.

Hena na ɔyɛ saa LDH nhwehwɛmu yi?

Mpɛn pii no, mogya mu nhwehwɛmu a ɛkyerɛ sɛ LDH wɔ hɔ no, oduruyɛfo a ɔhwɛ ntini mu yare a wɔatete no sɛ ɔntwe mogya na ɔyɛ . Nanso, akwahosan ho ɔbenfo biara a wɔatete no sɛ ɔntwe mogya betumi ayɛ eyi. Afei wɔde mogya no kɔ aduruyɛdan mu. Ɛhɔ no, nyansahufo bi a ɔwɔ aduruyɛdan mu hwehwɛ nhwɛsode no mu na ɔde mfiri titiriw (analyzers) di dwuma de susuw LDH dodow.

Ɛtɔ mmere bi a, ɛsɛ sɛ nnuruyɛfo susuw LDH dodow a ɛwɔ nipadua mu nsu afoforo mu, na ɛnyɛ mogya nkutoo mu. Sɛ nhwɛso no, w’amemene mu nsu (CSF), ahurututu mu nsu , anaa w’akyi berɛmo mu nsu . Wɔ tebea horow yi mu no, oduruyɛfo bi a ɔwɔ ntetee soronko bɛfa nhwɛsode bi.

Ɔkwan bɛn so na ɛsɛ sɛ misiesie me ho ma LDH nhwehwɛmu?

Mpɛn pii no, enhia sɛ wusiesie biribi titiriw biara ma LDH mogya mu nhwehwɛmu.

Nanso, sɛ wɔfa nipadua mu nsu foforo mu nsu bi, sɛnea yɛadi kan aka no a, ebia ɛho behia sɛ wɔyɛ ahosiesie bi. Wo duruyɛfo bɛkyerɛkyerɛ eyi mu akyerɛ wo saa bere no.

Dɛn na ɛba bere a wɔreyɛ LDH nhwehwɛmu no?

Sɛ wode mogya ma a, eyi ne nea ɛtaa ba:

• Wɔbɛtena akongua bi so. Afei akwahosan ho dwumayɛni bi bɛhwehwɛ ntini bi wɔ wo basa mu a ɛnyɛ den sɛ wobɛtwe mogya afi mu. Mpɛn pii no, wɔtwe mogya no fi wo nsateaa mu.
• Sɛ wohu ntini bi pɛ a, wɔhohoro baabi a ɛwɔ no yiye na wɔde aduru a ekum ɔyare mmoawa gu so.
• Afei, wɔde ade ketewaa bi hyɛ ntini no mu na wɔtwe mogya kakra. Saa bere yi de, ebia wobɛte nka sɛ wo ho ayɛ wo yaw kakra, te sɛ nea ntɛtea aka wo .
• Bere a wɔde ade no hyɛ mu wie no, wɔboaboa mogya kakraa bi ano wɔ afiri bi a wɔde sɔ hwɛ mu.
• Sɛ wɔfa mogya no wie a, woyi ade no na wɔde kotoku anaa gauze bi gu beae no na wɔde nhyɛso kakra gu so na ama mogya no agyae.
• Afei wɔde plaster gu beae no. Ɛno ne no.

Saa adeyɛ yi nyinaa taa gye nea ennu simma anum . Ɛyɛ adwuma a ɛyɛ ntɛm paa.

Sɛnea yɛadi kan aka ho asɛm no, ɛtɔ mmere bi a ebia nipadua mu nsu afoforo ho behia na wɔde asusuw `LDH`. Nsɛm a ɛtete saa no bi ne:

• Amemene mu Nsu (CSF) .
• Pleural Nsu a Wɔde Yɛ Nsu
• Nsu a Ɛma Awotwaa Mu

Sɛ ɛsɛ sɛ woyɛ sɔhwɛ a ɛte sɛɛ a, mma ɛnhaw wo. Wo duruyɛfo bɛkyerɛkyerɛ sɛnea wɔyɛ nhwehwɛmu no ne nea ɛsɛ sɛ wuhu mu kɔ akyiri.

Dɛn na ɛba wɔ LDH sɔhwɛ no akyi?

Sɛ wɔfa wo mogya anaa nipadua mu nsu foforo bi wie a, wɔde bɛkɔ aduruyɛdan mu akɔyɛ nhwehwɛmu. Sɛ sɔhwɛ no mu aba wie a, wo duruyɛfo no ne wo bɛbɔ nea efii mu bae no ho nkɔmmɔ.

So asiane bi wɔ LDH nhwehwɛmu mu?

Mogya a wɔde ma yɛ adeyɛ a wɔtaa yɛ wɔ aduruyɛ mu nhwehwɛmu mu. Ɛnyɛ asiane kɛse biara . Ebia akuru ne ɛyaw bi wɔ baabi a wɔtwee mogya no. Nanso ɛno befi hɔ ntɛm.

Bere tenten ahe na ebegye ansa na mahu nea efii LDH nhwehwɛmu no mu bae?

Mpɛn pii no, ɛsɛ sɛ wonya wo LDH nhwehwɛmu no mu aba wɔ da koro anaa nnanu ntam , nanso ɛtɔ mmere bi a ebetumi agye bere tenten kakra.

Sɛ woma wɔyɛ nhwehwɛmu yi wɔ ayaresabea anaa baabi a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ mu a, ebia wubenya nea efi mu ba no wɔ nnɔnhwerew kakraa bi mu .

Dɛn ne nea efi LDH nhwehwɛmu mu ba?

Mogya nhwehwɛmu amanneɛbɔ, kyerɛ sɛ, `LDH` nhwehwɛmu amanneɛbɔ, taa kura nsɛm a edidi so yi:

• Mogya mu nhwehwɛmu no din, anaa nea wɔsusuu wɔ wo mogya mu.
• Botae (i.e., nɔma) a ɛwɔ wo mogya mu nhwehwɛmu mu aba no.
• Range a ɛfata ma saa sɔhwɛ no.
• Nsɛm a ɛkyerɛ sɛ ebia nea efi mu ba no yɛ nea ɛfata, ɛnyɛ nea ɛfata, anaasɛ ɛkɔ soro anaasɛ ɛba fam.

Dɛn ne LDH (lactate dehydrogenase) dodow a ɛfata?

Nneɛma a ɛfata ma `LDH` no betumi ayɛ soronko kakra wɔ aduruyɛdan biako mu akɔ foforo mu. Sɛ wo nsa ka wo mogya mu nhwehwɛmu amanneɛbɔ a, ɛbɛkyerɛ pefee nea ɛyɛ nea ɛfata ma `LDH` ma saa aduruyɛdan no.

Nanso, mpɛn pii no, gyinapɛn ahorow a ɛfata ma LDH sɔhwɛ no te sɛ nea edidi so yi:

• Mmarima fam no : 135 – 225 units wɔ lita biara mu (U/L).
• Wɔ mmaa fam : Nkyekyɛmu a ɛwɔ lita biara mu (U/L) 135 – 214.

Sɛ wɔkyekyem pɛpɛɛpɛ a, LDH dodow a ɛwɔ mmofra nkumaa mu no taa kɔ soro sen mpanyimfo.

Sɛ wowɔ nsɛmmisa bi fa nea efi mu ba no ho a, hwɛ hu sɛ wubebisa wo duruyɛfo.

Sɛ me LDH dodow kɔ soro a, dɛn na ɛkyerɛ?

Sɛ wo LDH dodow dɔɔso sen sɛnea ɛte daa a, ɛda adi kɛse sɛ ɛkyerɛ sɛ ntini bi asɛe wɔ wo nipadua mu.Ɛkyerɛ sɛ biribi asi. Saa ɔsɛe no betumi afi yare a ɛtra hɔ kyɛ (a enni sabea), tebea a egye ntɛmpɛ (a emu yɛ den), anaa ɔyare mmoawa bi mu.

Ayaresa mu tebea horow a ebetumi ama LDH dodow akɔ soro no bi ne:

• Mogya a ɛtɔ kɔ nipadua mu
• Asaabo mu yare
• Ahurututu mu yare
• Mmɛn mu yare
• Ntini mu opira
• Ntini a ɛyɛ mmerɛw
• Nnompe a abubu
• Koma mu yare
• Pancreatitis a ɛyɛ yare
• Nyarewa bi te sɛ meningitis , amemene mu yare , mononucleosis (mono ), ne HIV .
• Kokoram ahorow bi , sɛ nhwɛso no, metastatic melanoma , multiple myeloma, lymphoma , awotwaa mu kokoram , ne mogya mu kokoram .

Afei nso, sɛ obi nya LDH dodow a ɛkɔ soro sen sɛnea ɛsɛ a, ebetumi akyerɛ sɛ kokoram ayaresa ntumi nyɛ adwuma yiye .

Bere a LDH nhwehwɛmu no betumi akyerɛ sɛ ebia wo nipadua no ntini asɛe anaasɛ wowɔ yare bi no, entumi nkyerɛ wo baabi pɔtee a asɛe no . Afei nso, sɛ mogya mu nkwammoaa kɔkɔɔ no mu paapae bere a wɔregye mogya no (hemolysis) a, ɛtɔ mmere bi a LDH bo no betumi ayɛ kɛse atoro . Enti sɛ nea efi mu ba no kyerɛ sɛ wo LDH dodow dɔɔso a, ɛda adi sɛ ebehia sɛ wo duruyɛfo yɛ nhwehwɛmu pii na ama wahu yare no pɛpɛɛpɛ.

Sɛ me LDH dodow kɔ soro a, so ɛsɛ sɛ mehaw me ho?

Sɛ mpo nea efii wo LDH nhwehwɛmu mu bae no kyerɛ sɛ wo LDH dodow dɔɔso a, ɛnkyerɛ ankasa sɛ wowɔ yare a emu yɛ den . Nha wo ho.

Nneɛma afoforo pii wɔ hɔ a ebetumi ama LDH dodow akɔ soro:

• Apɔw-mu-teɛteɛ a emu yɛ den .
• Nnuru bi , sɛ nhwɛso no aspirin , nnuru a ɛma obi dwensɔ , nnubɔne ne procainamide .

Afei nso, ebia mfomso bi sii bere a wɔregye nhwɛsode, wɔde rekɔ, anaa wɔresɔ ahwɛ no.

Sɛ wo duruyɛfo resi gyinae wɔ nea ebefi mu aba no ho a, obesusuw nneɛma pii ho, te sɛ nnuru a wonom mprempren, w’akwahosan ho abakɔsɛm, ne sɛnkyerɛnne ahorow a worehu.Ɔbɛsan nso akyerɛ wo sɛ ebia wuhia sɔhwɛ foforo anaasɛ ɛnte saa.

Sɛ wowɔ nsɛmmisa bi fa nea efi mu ba no ho a, nsuro sɛ wo ne wo duruyɛfo bɛkasa.

Sɛ me LDH dodow sua a, dɛn na ɛkyerɛ?

Ɛntaa mma koraa sɛ nea efi `LDH` sɔhwɛ mu ba no bɛba fam sen sɛnea ɛte daa .

Sɛ obi nya LDH dodow a ɛba fam saa a, ebetumi akyerɛ awosu mu tebea bi a ɛntaa nsi koraa a wɔfrɛ no Lactate Dehydrogenase A a enni nipadua no mu - Glycogen Storage Disease XI, anaa Lactate Dehydrogenase B a enni nipadua no mu.

Afei nso, ebia nnipa a wɔnom vitamin C pii no benya LDH nhwehwɛmu a ɛba fam wɔ atoro so .

Nsɛm bɛn na ɛsɛ sɛ mibisa me duruyɛfo?

Sɛ woayɛ LDH nhwehwɛmu a, ebia ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo nsɛm te sɛ eyinom:

• Dɛn na wususuw sɛ ebia ɛno nti na me `LDH` level a ɛkorɔn no aba?
• So ɛsɛ sɛ meyɛ nhwehwɛmu pii na ama mahu nea ɛde LDH dodow a ɛkɔ soro no ba ankasa?
• (Sɛ woyɛ kokoram ɔyarefo a) Dɛn na me `LDH` level ka fa me kokoram no mu den ne ne nkɔmhyɛ ho?
• (Sɛ wɔresa wo yareɛ bi a) Dɛn na me `LDH` level ka fa sɛdeɛ me tebea no reyɛ n’ade wɔ ayaresa ho?

Ade a ɛho hia sen biara a ɛsɛ sɛ wode sie w’adwenem (Take-Home Message) .

Ɛyɛ ade a ɛfata sɛ wobɛte ehu ne dadwen nka kakra bere a wuhu sɔhwɛ bi a ɛnyɛ ne kwan so no. Nanso kae sɛ, esiane sɛ wo `LDH` (lactate dehydrogenase) dodow dɔɔso nti, ɛnkyerɛ sɛ wowɔ yare a emu yɛ den na wuhia ayaresa.

Akyinnye biara nni ho sɛ wo duruyɛfo bɛka akyerɛ wo sɛ ebia ɛsɛ sɛ woyɛ nhwehwɛmu pii na ama woahu nea ɛde saa dodow a ɛnteɛ yi ba anaasɛ ɛnsɛ sɛ woyɛ saa. Nsuro anaasɛ ntwentwɛn wo nan ase sɛ wubebisa wo duruyɛfo nsɛm . Wɔwɔ hɔ sɛ wɔbɛboa wo. Ka biribiara a wowɔ wɔ w’akwahosan ho ho asɛm kyerɛ wɔn.

` LDH, lactate dehydrogenase, enzyme, ntini a ɛsɛe, mogya mu nhwehwɛmu, akwahosan, nhwehwɛmu