Dɛn ne Cholecystokinin? Momma yɛnka ho asɛm tiawa!

Hɛlo! Wo ho te sɛn? Ɛnnɛ yɛrebɛka nnuru sobɔfoɔ ketewa bi nanso ɛho hia paa wɔ yɛn nipadua mu ho asɛm. Wɔfrɛ no cholecystokinin. Ɛwom sɛ ebia edin no bɛyɛ te sɛ nea ɛware kakra de, nanso ɛho hia ma yɛn aduan a yɛde di dwuma. Ma yɛnhwɛ nea ɛyɛ, sɛnea ɛyɛ adwuma, ne sɛnea ɛho hia yɛn nipadua?

Dɛn ne saa cholecystokinin yi?

Sɛ yɛbɛka no tiawa a, cholecystokinin yɛ hormone . Wunim nea hormone yɛ? Wɔte sɛ abɔfo nkumaa a wɔde nkrasɛm fi baabi kɔ baabi wɔ yɛn nipadua mu. Nkwammoaa a ɛwɔ wo dwensɔtwaa ketewaa mu na ɛyɛ saa hormone a wɔfrɛ no cholecystokinin yi titiriw , titiriw bere a yɛadi awie no. Ɛno nti na ɛtɔ mmere bi a wɔfrɛ no pancreozymin no. Wɔtoo din saa efisɛ ɛyɛ adwuma wɔ dwensɔtwaa mu. Nanso nea ɛyɛ nwonwa no, saa cholecystokinin yi nso wɔ yɛn amemene ne yɛn ntini a ɛwɔ mfinimfini no mu . Nyansahufo da so ara rehu nea ɛyɛ pɛpɛɛpɛ wɔ hɔ. Nanso dwuma a edi wɔ aduan a wɔyam mu no yɛ kɛse.

Ɔkwan bɛn so na cholecystokinin fi ase yi fi nipadua mu?

Fa no sɛ woadi aduan a ɛyɛ dɛ. Ebia nam curry a aburow wom, anaa apataa asinasin, atoko bi, akutu sambol... Aduan a wudi kan no kɔ yafunu mu. Wɔyam no wɔ hɔ bere tiaa bi, na afei nkakrankakra efi ase du dwensɔtwaa ketewaa no fã a edi kan, duodenum . Ɛte sɛ keteke bi a ɛreba gyinabea bi. Afei, nkwammoaa titiriw bi wɔ wo duodenum no afasu mu, te sɛ detectives. Wɔfrɛ wɔn I-nkwaboaa . Saa I-nkwaboaa yi wɔ tumi a ɛyɛ nwonwa a ɛma wohu protein ne srade (kyerɛ sɛ, nam, mpataa, nkesua, nufusu, ngo) a ɛwɔ aduan a wudi mu. Sɛ wohu wɔn ara pɛ a, saa `(I-cells)` yi susuw sɛ, "Oh, afei ne bere a ɛsɛ sɛ yɛkɔ adwuma ase! Ɛsɛ sɛ yeyi yɛn adamfo cholecystokinin fi adi ntɛmntɛm," na wɔyɛ no na wogyae kɔ mogya no mu tẽẽ. Efi hɔ no, n’akwantu a ɛho hia no fi ase.

Dɛn na cholecystokinin yɛ yɛn nipadua?

Eyi ne baabi a adwuma ankasa no kɔ so bere a cholecystokinin akɔ mogya no mu akyi. Ɛnyɛ nea ɛtra hɔ ara kwa. Ɛfa mogya no mu, kɔ akwaa biara mu, na ɛyɛ adwuma a ɛho hia pii.

Nea ɛyɛ bere a ɛreyɛ aduan

Momma yɛnhwɛ sɛnea cholecystokinin di dwuma titiriw wɔ aduan a wɔyam mu:

• Ɛma akisikuru no twetwe: Ɛka kyerɛ wo akisikuru no sɛ, "Okay, afei wowɔ bile no wɔ wo mu."Fa bi gu dwensɔtwaa ketewa no mu. Ɛyɛ bere a ɛsɛ sɛ yɛkɔ adwuma!" Mma ɛnyɛ wo nwonwa, edin 'cholecystokinin' no kyerɛ sɛ 'ɛbɛkanyan akisikuru no'. Saa bile yi ne nea ɛboa ma ngo, anaa srade, a yedi no tew, na ɛpaapae mu yɛ no nketenkete. Te sɛ nea yɛde samina hohoro nkuku no.
• Ɛkanyan dwensɔtwaa no: Ɛsan nso de sɛnkyerɛnne bi kɔ dwensɔtwaa no so, na ɛka sɛ, "Ɛsɛ sɛ wode wo aduan mu enzymes nso kɔ dwensɔtwaa ketewa no mu. Adwuma kɛse bi wɔ ha a ɛsɛ sɛ woyɛ." Wonyaa edin foforo, "pancreozymin," fii adwuma yi a ɛfa dwensɔtwaa ho .
• Protein ne srade a ɛpaapae: Nsu a efi akisikuru mu ne enzymes a efi dwensɔtwaa mu no bom paapae protein ne srade a ɛwɔ aduan a yedi mu no mu nketenkete sɛnea ɛbɛyɛ a nipadua no betumi atwe. Eyi te sɛ ɔbo kɛse bi a wɔabubu ayɛ no nketenkete.
• Ɛhwɛ yafunu mu a ɛda mpan so: Bere a adwuma yi rekɔ so wɔ dwensɔtwaa ketewa no mu no, cholecystokinin ka kyerɛ yafunu no sɛ, "Mma ɛnhaw wo, twɛn simma biako. Mfa aduan foforo nkɔ dwensɔtwaa ketewa no mu kosi sɛ aduan a atwam no bɛyam." Wɔfrɛ eyi sɛ yafunu mu nneɛma a ɛda mpan a wɔbara . Eyi kyerɛ sɛ dwensɔtwaa ketewa no nnya aduan pii prɛko pɛ, na mmom enya bere de yam no yiye.
• Ɛtew aduan ho akɔnnɔ so : Bere a yɛredidi no, cholecystokinin ma yɛn yafunu te nka sɛ ɛyɛ ma. Ɛsan nso kanyan vagal ntini a ɛwɔ yafunu no fasu mu no, na ɛde sɛnkyerɛnne bi kɔ amemene no so sɛ, "Ɛdɔɔso, mayɛ me ma, nnidi bio." Eyi nti na yɛte nka sɛ yɛayɛ ma bere a yɛadi adidi akyi bere tiaa bi no.
• Peristalsis fi ase: Awiei koraa no, ɛsɛ sɛ wɔde aduan a wɔayam yi sian kɔ dwensɔtwaa no mu . Ntini a ɛwɔ dwensɔtwaa no mu a wɔfrɛ no peristalsis , a ɛtwetwe ne ho a ɛyɛ dɛ no boa eyi. Ɛte sɛ nea worepia aduan no afa dwensɔtwaa no mu .

Wo de susuw sɛnea hormone biako yi boa yɛn aduan mu nneɛma kɔ so yiye no ho hwɛ!

Nkɛntɛnso a enya wɔ amemene ne ntini ahorow so

Wɔ boa a ɛboa wɔ aduan mu akyi no, wɔahu nso sɛ cholecystokinin di dwuma wɔ yɛn amemene ne yɛn ntini a ɛwɔ mfinimfini no mu. Wɔda so ara reyɛ eyi ho nhwehwɛmu, nanso nea wɔahu de besi nnɛ no ho hia yiye. Titiriw no, ebetumi aboa wɔ dadwen neƐte sɛ nea ɛne adwenemyare tebea horow te sɛ ehu a ɛma obi ho popo wɔ abusuabɔ . Nhwehwɛmu ahorow bi ada no adi sɛ cholecystokinin dodow a ɛkɔ soro wɔ amemene no mu no ma dadwen yɛ kɛse. Eyi yɛ nea emu yɛ den kakra, nanso ɛda adi pefee sɛ enya yɛn nkate mu nhyehyɛe nso so nkɛntɛnso. Wɔabɔ amanneɛ nso sɛ ɛka nipadua no hyew a wɔhwɛ so, anaasɛ ɔhyew a wɔhwɛ so . Wɔkyerɛ sɛ sɛ wɔde twitwiw amemene no mu a, ɛbɛma obi anya atiridii, na sɛ wɔde gu nipadua no afã afoforo a, ɛbɛma nipadua no mu hyew akɔ fam, tebea a ɛma nipadua no hyew kɔ fam. Nanso, nhwehwɛmu foforo ho hia na ama yɛate eyi ase pɛpɛɛpɛ.

Ɛhe na wohu cholecystokinin wɔ yɛn nipadua mu?

Te sɛ hormone afoforo no, cholecystokinin tu fa yɛn nipadua nyinaa mu wɔ yɛn mogya mu . Ɛnam ntini soronko a ɛwɔ saa akwaa no nkwammoaa so so "kasa" kyerɛ akwaa ahorow. Saa nneɛma a ɛma wogye nneɛma yi te sɛ apon. Sɛ safe a wɔfrɛ no cholecystokinin wɔ hɔ nkutoo a na apon no bue, na afei nkwammoaa no nsa ka nkrasɛm no. Wɔ yɛn aduan mu nhyehyɛe mu no, wohu cholecystokinin (CCK) agyefo wɔ akisikuru ntini, yafunu ne dwensɔtwaa a ɛkata so, ne dwensɔtwaa mu. Wobetumi ahu saa ntini ahorow yi nso wɔ amemene no afã horow ne ntini a ɛwɔ mfinimfini no mu.

Dɛn ne nyarewa a ɛne cholecystokinin wɔ abusuabɔ?

Nyarewa bi wɔ hɔ a wɔahu cholecystokinin a ɛba fam wɔ mu. Nanso, wonnya nhuu sɛ ebia eyi fi yare no mu anaasɛ nea ɛde yare no ba. Nhwehwɛmu da so ara kɔ so wɔ eyi ho. Sɛ nhwɛso no, ebia cholecystokinin dodow a ɛba fam no ne tebea horow te sɛ gastroparesis , tebea a ɛma yafunu no mu da mpan yiye na aduan akɔhyɛ yafunu no mu, ne biliary dyskinesia, tebea a ɛma akisikuru no nyɛ adwuma yiye na ennyi bile yiye no wɔ abusuabɔ. Afei nso, nyansahufo reyɛ nhwehwɛmu wɔ sɛnea nsakrae ahorow a ɛwɔ awosu mu nkwaadɔm a ɛka ho wɔ cholecystokinin a wɔyɛ mu no ne dadwen ne nipadua mu nneɛma a ɛsakra no bi wɔ abusuabɔ no mu. Nhwehwɛmu bi kyerɛ sɛ saa awosu mu nsakrae yi betumi asakra ɔkwan a cholecystokinin fa so ne amemene no di nkitaho na ɛdi dadwen anaa ɔkɔm ho nsɛnkyerɛnne so.

Abusuabɔ bɛn na ɛda cholecystokinin ne kɛseyɛ mmoroso ntam?

Moseyɛ mmoroso, anaa kɛseyɛ mmoroso yɛ ɔhaw ma nnipa pii nnɛ. Nyansahufo nso reyɛ nhwehwɛmu denneennen sɛ ebia abusuabɔ bi da kɛseyɛ mmoroso ne cholecystokinin ntam anaa. Nneɛma a wɔahu no bi yɛ nwonwa koraa. Sɛ nhwɛso no, wɔahu sɛ nnipa a wɔwɔ ɔkwan pɔtee bi (nsakrae) wɔ cholecystokinin awosu mu abɔde mu no, bɛyɛ 60% na ɛbɛyɛ kɛse mmoroso sen afoforo. Adanse bi nso wɔ hɔ a ɛkyerɛ sɛ nnipa a wɔayɛ kɛse mmoroso kɛse (kɛseyɛ mmoroso a ɛto so III), kyerɛ sɛ, nnipa a wɔayɛ srade kɛse, no so atew cholecystokinin ho nkate so. Eyi kyerɛ sɛ ɛwom sɛ wɔwɔ cholecystokinin wɔ wɔn nipadua mu de, nanso ebia wɔrentumi nte ‘mayɛ’ sɛnkyerɛnne a ɛde ma wɔn no nka yiye. Cholecystokinin ne hormone foforo a wɔfrɛ no leptin yɛ adwuma de siw ɔkɔm ano. Ebia nnipa a wɔayɛ kɛse mmoroso no ntumi nkari pɛ wɔ ɔkɔm ne nea ɛyɛ ma ho sɛnkyerɛnne ahorow mu wɔ wɔn amemene mu. Enti, cholecystokinin a wɔbɛte ase nso betumi aboa ma wɔanya ayaresa a wɔde sa kɛseyɛ mmoroso.

Dɛn ne saa cholecystokinin nhwehwɛmu yi?

Cholecystokinin nhwehwɛmu hwehwɛ sɛ wode aduru bi a wɔfrɛ no cholecystokinin bɛma wo gallbladder no na akanyan no ma atwetwe. Ɛtɔ mmere bi a wɔyɛ eyi sɛ HIDA scan a ɛyɛ nuklea aduruyɛ mu mfoniniyɛ sɔhwɛ titiriw bi no fã. Mma edin no nnyɛ wo hu, eyi yɛ sɔhwɛ a ahobammɔ wom yiye. Nea ɛba ni: 1. Nea edi kan no, mfiridwumayɛfo bi de radioactive isotope anaa tracer kakraa bi gu wo ntini mu. Ɛte sɛ nea woreyɛ akwan kakraa bi ho mfonini wɔ wo nipadua mu na woahwɛ nea ɛrekɔ so wɔ so. 2. Saa tracer yi tu kwan kɔ wo mmerɛbo ne biliary system (gallbladder, bile ducts) mu. 3. Afei, wɔde mfoninitwa afiri soronko bi (scanner) kyere mframa a saa tracer yi de ba no na wɔde kyerɛ mfonini ahorow wɔ kɔmputa so. Saa mfonini ahorow yi ma oduruyɛfo no hu sɛnea wɔyɛ bile no ne sɛnea ɛkɔ. Sɛ wo duruyɛfo pɛ sɛ ohu nea ɛba bere a wo gallbladder no twetwe a, obetumi de cholecystokinin aka HIDA scan no ho sɛ anammɔn foforo. Saa bere no, mfiridwumayɛfo no de cholecystokinin bɛhyɛ wo ntini mu. Afei, wɔtwa mfonini pii. Te sɛ cholecystokinin a wonya fi awosu mu wɔ wo dwensɔtwaa mu no, saa ara na cholecystokinin a wɔde twitwiw wo dwensɔtwaa mu no kanyan akisikuru no ma ɛtwetwe. Nnuruyɛfo hyɛ nhwehwɛmu yi sɛ wɔmfa nhwɛ sɛ ɔhaw bi wɔ wo gallbladder no dwumadi mu ne sɛ ebia ɛregyae bile yiye anaa.

So nnuru bi wɔ hɔ a wɔde sa cholecystokinin?

Ɛde besi ha no, aduruyɛ biara nni hɔ a wɔde cholecystokinin di dwuma tẽẽ. Ɛne sɛ, wɔmfa cholecystokinin mma sɛ yare bi ano aduru. Nanso, wɔde adi dwuma de ahu nnuru foforo na wɔasɔ ahwɛ. Sɛ nhwɛso no, nhwehwɛmufo rebɔ mmɔden sɛ wɔbɛyɛ nnuru a ɛte sɛ cholecystokinin wɔ aduan ho akɔnnɔ a ɛtew so na ɛboa ma obi mu duru so tew mu. Afei nso, cholecystokinin wɔ ɔfã titiriw bi a wɔfrɛ no CCK-4 . Wonim sɛ saa CCK-4 yi ma nkurɔfo te dadwen ne ehu nka. Enti, ɛtɔ mmere bi a nyansahufo de CCK-4 di dwuma de sɔ sɛnea nnuru foforo a wɔde ko tia dadwen yɛ adwuma yiye no hwɛ.

Nneɛma a ɛho hia paa a ɛsɛ sɛ yɛkae (Take-Home Message) .

Enti, efi nea yɛaka afa cholecystokinin ho no, wubetumi akae nneɛma a ɛho hia sen biara no bi. Seesei woate adwuma kɛse a saa hormone ketewa yi yɛ wɔ yɛn nipadua mu no ase, ɛnte saa?

• Cholecystokinin yɛ hormone a ɛho hia ma aduan a wɔyam . Ɛne akwaa a ɛka aduan mu nyinaa te sɛ akisikuru ne dwensɔtwaa "kasa" na ɛboa wɔn ma wɔyɛ wɔn adwuma yiye.
• Nnuruyɛfo nso de di dwuma sɛ ade a wɔde kanyan obi a wotumi de ho to so de sɔ akisikuru dwumadi hwɛ.
• Ɛboa nso ma wodi ɔkɔm so . Wɔahu nso sɛ ebia cholecystokinin dwumadi a asɛe no ne tebea horow te sɛ kɛseyɛ mmoroso wɔ abusuabɔ.
• Nyansahufo kɔ so sua dwuma a edi wɔ amemene ne ntini ahorow mu, titiriw abusuabɔ a ɛda ne tebea horow te sɛ dadwen ne ehu ntam no ho ade.

Enti, yɛn nipadua yɛ mfiri a ɛyɛ nwonwa ankasa! Ɛyɛ nwonwa sɛnea nneɛma nketenkete yi betumi de nsakrae kɛse aba yɛn akwahosan mu, ɛnte saa? Hwɛ wo nipadua so, na saa nnamfo nkumaa yi bɛhwɛ wo!

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Cholecystokinin, Cholecystokinin, Hormone, Nnuan a wɔyam, Akisikuru, Dwensɔtwaa, Ɔkɔm, Kɛse mmoroso, HIDA scan