So wo nsa ne w’anim resakra nkakrankakra na ɛreyɛ kɛse? Momma yɛnka Acromegaly ho asɛm.

So woate nka pɛn sɛ wo mpaboa kɛse reyɛ kɛse, anaasɛ afei mpɛtea a na wohyɛ no abata wo nsateaa ho? Ebia w’anim nsusuwii yɛ soronko kakra bere a wohwɛ mfonini dedaw no? Saa nneɛma yi mu pii sisi bere tenten, ɛtɔ mmere bi a mfe pii, enti yɛmfa yɛn adwene nsi so kɛse. Nanso eyi betumi ayɛ tebea bi a ɛntaa nsi a wɔfrɛ no Acromegaly ho sɛnkyerɛnne . Mma ɛnhaw wo, yɛbɛka biribiara ho asɛm wɔ nsɛm a ɛnyɛ den mu.

Sɛ yɛbɛka no tiawa a, dɛn ne Acromegaly?

Acromegaly yɛ tebea a yɛn nipadua no yɛ onyin hormone, anaasɛ Growth Hormone (GH) pii dodo de ba. Saa hormone yi boa yɛn ma yenyin bere a yɛyɛ mmofra no. Nanso, sɛ saa hormone yi kɔ so yi fi mu bere a yɛanyin awie, kyerɛ sɛ, bere a yɛabɛyɛ mpanyimfo akyi a, yɛn nipadua no afã horow bi, titiriw nsa, anan, ne anim nnompe fi ase nyin kɛse wɔ ɔkwan a ɛnteɛ so.

Wɔtaa hu saa tebea yi wɔ nnipa a wɔadi mfe mfinimfini mu. Nanso eyi nkyerɛ sɛ ɛnkɔ so wɔ mmerante ne mmabaa mu. Sɛ onyin hormone kɔ soro saa kwan yi so wɔ ne mmofraase a, wɔfrɛ tebea no gigantism. Afei wonyin tenten wɔ ɔkwan soronko so.

Dɛn nti na acromegaly nya nkɔso? Dɛn na ɛde ba?

Nea enti titiriw a ɛte saa ne ntini ketewaa bi a ne kɛse te sɛ pea wɔ yɛn amemene no ase. Yɛfrɛ no Pituitary Gland . Nea ɛtaa de Acromegaly ba ne akisikuru a ɛnyɛ kokoram (a ɛnyɛ papa) a ɛwɔ saa ntini yi mu. Wɔfrɛ saa akisikuru yi Pituitary Adenoma . Saa akisikuru yi kanyan pituitary gland no na ɛma onyin hormone (GH) pii ba.

Saa GH hormone a ɛboro so yi boaboa ano wɔ yɛn mogya mu na ɛma mmerɛbo no yɛ hormone foforo a wɔfrɛ no IGF-1 (Insulin-like Growth Factor-1) . Saa IGF-1 hormone no na ɛma yɛn nnompe ne yɛn akwaa afoforo nyin wɔ ɔkwan a ɛnteɛ so. Ɛka ɔkwan a yɛn nipadua no fa so di asikre ne srade so nso, na ɛma asiane a ɛwɔ hɔ sɛ yebenya nyarewa afoforo no yɛ kɛse.

Ɛntaa mma koraa sɛ akisikuru a ɛba dwensɔtwaa, mmerɛbo, anaa amemene no afã afoforo nso betumi de tebea yi aba. Nhwehwɛmu ada no adi sɛ ebia awosu mu nneɛma bi nso di dwuma.

Dɛn ne acromegaly ho sɛnkyerɛnne ahorow?

Saa sɛnkyerɛnne ahorow yi taa da adi nkakrankakra, enti ebia ebegye bere kakra ansa na woahu nsonsonoe a ɛwɔ mu.

Ɔkwan bɛn so na wobetumi ahu yare yi?

Ɛho hia sɛ wuhu tebea yi ntɛm ara sɛnea wubetumi. Sɛ wokɔ oduruyɛfo nkyɛn esiane saa sɛnkyerɛnne ahorow yi nti a, obebisa wo nsɛm te sɛ:

• Nsakrae bɛn na wuhu?
• Bere bɛn na wudii kan huu nsakrae yi?
• Wote nka dɛn mprempren?

Afei, wɔyɛ nhwehwɛmu ahorow pii de si so dua sɛ wɔahu yare no.

Sɔhwɛ atitiriw

• Mogya mu nhwehwɛmu: Wɔyɛ mogya mu nhwehwɛmu de hwɛ sɛ ebia wo IGF-1 hormone dodow kɔ soro ma wo mfe a woadi anaa.
• Glucose Tolerance Test: Ɛha yi, wɔma wo anonne a asikre wom na wɔde nnɔnhwerew abien susuw asikre a ɛwɔ wo mogya mu ne GH hormone dodow. Mpɛn pii no, ɛsɛ sɛ GH dodow so tew bere a wɔanom asikre awie no. Sɛ wɔannyɛ saa, na wɔkɔ so kɔ soro a, ɛyɛ acromegaly ho sɛnkyerɛnne.

Sɔhwɛ afoforo

• MRI anaa CT scan: Saa scan ahorow yi boa ma wohu pituitary tumor.
• X-ray nhwehwɛmu: Hwɛ sɛ nnompe mu ayɛ den anaa.
• Echocardiogram: Ɛyɛ koma no mu nhwehwɛmu a wɔde ultrasound yɛ de hwɛ sɛ ebia wɔanya koma no so nkɛntɛnso anaa.
• Colonoscopy: Hwɛ sɛnea akyi berɛmo no akwahosan te.
• Dae Ho Adesua: Hwɛ sɛ wowɔ Sleep Apnea anaa.

Dɛn ne ayaresa ahorow no?

Wo duruyɛfo no begyina mfe a woadi, w’akwahosan, ne sɛnea wo tebea no mu yɛ den so akyerɛ ayaresa nhyehyɛe a ɛfata wo sen biara. Ayaresa atitiriw abiɛsa na ɛwɔ hɔ.

1. Oprehyɛn a wɔyɛ:

Mpɛn pii no, ayaresa a edi kan ne oprehyɛn a wɔde yi pituitary akisikuru no. Eyi ho hia titiriw sɛ akisikuru no repiapia ntini ahorow a ɛka anisoadehu no a. Oduruyɛfo a ɔyɛ oprehyɛn no nam ntwitwiridii ketewaa bi a ɛfa hwene no mu anaa anofafa a ɛwɔ soro no mu so yi akisikuru no. Ebia yare no ho sɛnkyerɛnne befi ase ayɛ yiye wɔ oprehyɛn no akyi nna kakraa bi.

2. Nnuru a wɔde di dwuma:

Sɛ akisikuru no asinasin bi aka wɔ oprehyɛn akyi anaasɛ wuhia mmoa pii a wode bɛhwɛ wo hormone dodow so a, wo duruyɛfo bɛkyerɛw wo nnuru. Saa nnuru yi ma wo GH dodow so tew anaasɛ esiw nkɛntɛnso a enya wɔ nipadua no so no ano.

• Somatostatin a ɛne ne ho di nsɛ (sɛ nhwɛso no, lanreotide, octreotide) .
• Nnuru a ɛko tia onyin hormone agyefo (e.g. pegvisomant) .
• Nnuru a ɛma dopamine (sɛ nhwɛso no, cabergoline) .

3. Mframa a Wɔde Yɛ Ayaresa:

Sɛ akisikuru no afã horow da so ara ka wɔ oprehyɛn ne nnuru akyi, anaasɛ ɛsɛ sɛ wɔtew GH dodow so bio a, wɔde mframa a wɔde sa yare di dwuma. Eyi ma akisikuru no ntumi nnyin na ɛtew GH a wɔyɛ no so. Nnɛyi akwan te sɛ stereotactic radiosurgery betumi de mframa a ɛdɔɔso akɔ akisikuru no mu a ɛrensɛe ntini a ɛte apɔw.

Nsɛnnennen a ebetumi aba sɛ wɔansa a

Acromegaly betumi de akwahosan ho haw a emu yɛ den aba sɛ wɔansa no yiye a, enti mmu w’ani ngu tebea yi so.

• Koma ne ntini mu yare
• Asikyireyareɛ
• Mogya mmoroso
• Ntini mu Yare (Osteoarthritis) .
• Carpal Tunnel Syndrome a Ɛyɛ Nnipa a Wɔte Ase
• Sleep Apnea a Ɛyɛ Fɛ
• Anisoadehu a wɔhwere
• Asiane a ɛkɔ soro sɛ obi benya kokoram wɔ akyi berɛmo mu
• Akyi berɛmo mu ntini a wɔhyɛ