Ebia woate asɛmfua "hormones" no pii, ɛnte saa? Saa nkwaadɔm yi di nneɛma pii a ɛwɔ yɛn nipadua mu, te sɛ nkate, onyin, nna, ne ɔkɔm so. Enti, ɛnnɛ yɛrebɛka hormone soronko bi a ɛho hia yiye ma nna mu nkɔso ne tumi a wɔde bɛwo mma, kyerɛ sɛ, awo ho asɛm. Saa hormone no ne FSH, anaa Follicle-Stimulating Hormone. Ɛwom sɛ ebia ɛbɛyɛ te sɛ nea edin no yɛ den kakra de, nanso ne dwumadi no yɛ mmerɛw yiye sɛ wɔbɛte ase.
Sɛ yɛbɛka no tiawa a, dɛn ne FSH?
FSH yɛ hormone a pituitary gland, ntini ketewaa bi a ɛwɔ yɛn amemene mu no na ɛyɛ. Ne dwumadi titiriw ne sɛ ɛbɛhwɛ sɛnea mmea mu mmadwoa ne mmarima awotwaa no yɛ adwuma.
Sɛ wote edin no a, ebia ebinom besusuw sɛ eyi yɛ biribi a ɛfa nhwi a ɛyɛ mmerɛw ho. Nanso ɛnte saa. Nkwammoaa kuw foforo bi a wɔfrɛ no androgens ka nhwi nyin. FSH nyaa ne din efisɛ ɛkanyan kotoku nketewa a nsu ahyɛ mu ma a wɔfrɛ no ovarian follicles a ɛwɔ mmea awotwaa mu. Nkesua na ɛwɔ saa ntini ahorow yi mu.
Dɛn ne FSH hormone no dwumadi ahorow?
FSH hormone no ho hia wɔ akwan horow so wɔ yɛn asetra mu mmere ahorow mu. Ma yɛnhwɛ sɛnea ɛbɛyɛ.
Sɛnea ɛbɛyɛ a akokoaa no nyin wɔ awotwaa mu
Nea ɛyɛ nwonwa no, wɔ nyinsɛn no fã a ɛto so abien ne abiɛsa mu, efi bɛyɛ adapɛn 13 kosi awo no, akokoaa no pituitary gland nso fi ase yɛ nkwaadɔm a wɔfrɛ no FSH ne LH (Luteinizing Hormone). Saa nkwaadɔm yi dodow kɔ soro bɛyɛ nyinsɛn no mfinimfini, bere a akokoaa no awotwaa mu ntini anaa seminiferous tubule a edi kan no nyin no.
Wɔ mmerantebere ne mmabaabere mu
Wɔ mmofraase no, FSH dodow taa sua koraa. Nanso, bere a mmerantebere ne mmabaabere rebɛn, mpɛn pii no mfe 10 kosi 14 no, hypothalamus a ɛwɔ amemene no mu no yɛ hormone bi a wɔfrɛ no GnRH (Gonadotropin-releasing hormone). Saa GnRH yi ma pituitary gland no kyerɛ sɛ efi ase yɛ FSH ne LH. Eyi ne bere a nna mu onyin ne nipadua mu nsakrae a ɛbata ho no fi ase.
- Mmarimaa: FSH ne LH bom yɛ adwuma de kanyan mmadwoa no ma ɛyɛ testosterone . Saa hormone yi na ɛma nsakrae ba mmarimaa mu wɔ wɔn mmabunbere mu, te sɛ nipadua mu nhwi nyin, ɛnne a emu dɔ, ne mmadwoa a ɛba.
- Wɔ mmeawa mu: FSH ne LH bom kanyan awotwaa no ma ɛyɛ estrogen hormone . Saa hormone yi na ɛma nufu no nyin na ɛma brayɛ fi ase .
Mmea a wɔrekɔ brayɛ mu
Dwuma titiriw a FSH hormone no yɛ ne sɛ ɛbɛhwɛ ɔbea a ɔrekɔ brayɛ mu no brayɛ so. Sɛ yɛbɛka no tiawa a, FSH kanyan ntini a ɛwɔ awotwaa mu no nyin, na esiesie nkesua no ma ovulation. Bere a saa ntini ahorow yi nyin no, ɛma estrogen ne progesterone kakraa bi kɔ mogya no mu.
Wɔ nnafua 6 ne 14 ntam wɔ brayɛ mu no, FSH ma ntini pii a ɛwɔ awotwaa mu fi ase nyin. Nanso ebedu nnafua 10-14 no, saa ntini yi mu biako pɛ na anyin abɛyɛ nkesua a ɛho akokwaw koraa. Bɛyɛ da a ɛto so 14 no, hormone LH no kɔ soro mpofirim. Eyi ma ntini a ɛho akokwaw koraa no pae na ɛma ɛwo no fi hɔ. Eyi ne nea yɛfrɛ no ovulation .
Sɛ ovulation wie a, follicle a apaapae no bɛyɛ bere tiaa mu ntini a wɔfrɛ no corpus luteum, a ɛma hormone progesterone pii. Saa progesterone yi ma FSH a wɔyɛ no gyae na esiesie awotwaa no fasu no ma nyinsɛn.
Nkwaa no fa awotwaa no mu bɛyɛ nnanu ansa na adu awotwaa no mu. Sɛ mmadwoa bi ma ɛwo no yiye wɔ saa bere yi mu a, nyinsɛn ba. Sɛ nyinsɛn no amma a, corpus luteum no sɛe wɔ brayɛ no awiei na progesterone dodow so tew. Afei FSH dodow fi ase kɔ soro bio, na brayɛ a edi hɔ no fi ase.
Mmarima de
Adwuma titiriw a ɔbarima hormone FSH yɛ ne sɛ ɛbɛkanyan mmadwoa a wɔyɛ . FSH nso boa ma mmadwoa kɔ so yɛ adwuma denam testosterone a LH na ɛyɛ adwuma no so.
Ɔkwan bɛn so na wɔhwɛ FSH a wɔyɛ so?
Eyi yɛ nhyehyɛe a ɛyɛ den mmom a wɔde di dwuma. Ɛte sɛ ɔkwan a adwumakuw kɛse bi fa so yɛ adwuma. Yɛfrɛ no hypothalamic-pituitary-gonadal axis. Amemene no afã horow (hypothalamus, pituitary gland) ne gonads (ovaries/testicles) a ɛwɔ saa nhyehyɛe yi mu no ne wɔn ho wɔn ho di nkitaho bere nyinaa.
1. Mfiase: Nea edi kan no, hypothalamus no yɛ hormone bi a wɔfrɛ no GnRH.
2. Nkannyan: Saa GnRH yi kɔ pituitary gland no mu na ɛka kyerɛ no sɛ ɛnyɛ hormone FSH ne LH.
3. Adeyɛ: FSH ne LH a pituitary gland na ɛyɛ no fa mogya no mu na ɛkyekyere awotwaa anaa mmadwoa (gonads) de hwɛ wɔn dwumadi so.
4. Nsɛm a wɔka: Afei, nkwaadɔm a awotwaa ne awotwaa no yɛ (te sɛ estrogen ne testosterone) no san de nsɛnkyerɛnne kɔ amemene no mu ma ɛkyerɛ no GnRH, FSH, ne LH dodow a ɛsɛ sɛ ɛyɛ. Eyi kɔ so wɔ kyinhyia mu.
Sɛ nhyehyɛe yi mu baabiara ntumi nyɛ adwuma yiye kakra a, hormone ahorow a ɛkari pɛ no nyinaa betumi asɛe.
FSH dodow a ɛfata te dɛn?
FSH dodow a ɛfata no gu ahorow gyina mfe a wɔadi, ɔbarima anaa ɔbea, ne da a mmea kɔ brayɛ so. Nea ɛho hia no, sɛnea ɛte daa no betumi ayɛ soronko kakra wɔ labs ahorow ntam. Enti, ɛho hia sɛ wode nea efi mu ba no toto lab no dodow a ɛfata wɔ w’amanneɛbɔ no so no ho. Sɛ wowɔ nsɛmmisa bi fa nea afi mu aba no ho a, hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa.
Ase hɔ no yɛ gyinapɛn ahorow a wogye tom. Nsusuwii a wɔde susuw nneɛma ne mIU/mL (milli-amanaman ntam nsusuwii wɔ mililita biara mu).
| Prama | FSH dodow a ɛfata ma mmarima (mIU/mL) . |
|---|---|
| Ansa na ɔbɛyɛ mmerantebere ne mmabaabere | 0 kosi 5.0 |
| Wɔ mmerantebere ne mmabaabere mu | 0.3 kosi 10.0 |
| Wɔ mpanyin afe so | 1.5 kosi 12.4 |
| Prama | FSH dodow a ɛfata ma mmea (mIU/mL) . |
|---|---|
| Ansa na ɔbɛyɛ mmerantebere ne mmabaabere | 0 kosi 4.0 |
| Wɔ mmerantebere ne mmabaabere mu | 0.3 kosi 10.0 |
| Wɔ mpanyin afe so (menopause) . | 4.7 kosi 21.5 (eyi gu ahorow gyina kyinhyia no so) . |
| Bere a Wɔagyae Brayɛ akyi | Efi 25.8 kosi 134.8 |
So FSH dodow a ɛfata wɔ hɔ ma nyinsɛn?
Eyi yɛ asɛmmisa a ɛho hia paa ma awarefo a wɔwɔ anidaso sɛ wɔbɛwo mma. FSH dodow a wobesusuw ho hia bere a wɔreyɛ awo ho nhwehwɛmu no. Bere a eye sen biara a ɛsɛ sɛ woyɛ saa sɔhwɛ yi ne brayɛ no da a ɛto so 3 (wobu da a edi kan a wobɛkɔ brayɛ no sɛ da a ɛto so 1).
Nhwehwɛmu bi a wɔyɛe wɔ nea efii IVF (In Vitro Fertilization) ayaresa mu bae ho no kyerɛe sɛ wɔn a wɔn FSH dodow nnu 15 mIU/mL da a ɛto so 3 no nyaa hokwan kɛse sɛ wobenyinsɛn sen wɔn a FSH dodow nnu 15 kosi 24.9 no. Wɔn a na FSH dodow boro 25 no nyaa nyinsɛn hokwan a ɛba fam mpo.
Nanso eyi nkyerɛ sɛ wubetumi agyina FSH dodow nkutoo so asi gyinae. Nneɛma afoforo pii wɔ hɔ a ɛka awo. Enti eye sɛ wo ne wo duruyɛfo bɛkasa afa wo FSH dodow ho, ne awo ho haw biara nso.
Dɛn na FSH dodow a ɛkɔ soro kyerɛ?
Mpɛn pii no, sɛ FSH dodow dɔɔso sen sɛnea ɛte daa a, ɛkyerɛ sɛ ɔhaw bi wɔ awotwaa anaa awotwaa mu .
Fa no sɛ awotwaa anaa mmadwoa no ntumi nyɛ estrogen anaa testosterone a ɛdɔɔso. Afei, pituitary gland a ɛwɔ amemene no mu no hu eyi na wosusuw sɛ, "Okay, ɛsɛ sɛ mesoma FSH pii na ama saa nneɛma yi ayɛ adwuma," na ɛma FSH pii kɔ mogya no mu. Nanso esiane ɔhaw bi a ɛwɔ gonads no mu nti, wontumi nyɛ wɔn ade yiye wɔ FSH dodow a ɛreba no ho.Yɛfrɛ tebea yi primary hypogonadism . Nea edidi so yi betumi de eyi aba:
- Awo mu dɛmdi ahorow:
- Klinefelter yare a ɛwɔ mmarima mu
- Turner syndrome a ɛwɔ mmea mu
- Nneɛma a ɛde ba akyiri yi:
- Mframa anaa nnuru a wɔde sa kokoram
- Apirakuru a ɛba mmadwoa anaa mmadwoa mu
- Hormone dodow a ɛso tew bere a obi nyin no
- Tebea ahorow bi a nipadua no tumi ko tia nyarewa
- Nyarewa te sɛ akisikuru
Afei nso, brayɛ a ɛma obi gyae brayɛMmea FSH dodow kɔ soro fi awosu mu bere a wɔreyɛ ovulation no. Eyi yɛ ade a ɛfata. Sɛ mmofra FSH dodow boro wɔn mfe so na nna mu su ahorow renya nkɔso a, ebetumi ayɛ sɛnkyerɛnne a ɛkyerɛ sɛ wɔadi mmabunbere ntɛm .
Dɛn na FSH dodow a ɛba fam kyerɛ?
Sɛ FSH dodow sua sen sɛnea ɛte daa a, ɛtaa kyerɛ sɛ ɔhaw bi wɔ pituitary gland anaa hypothalamus . Esiane sɛ amemene no nkyerɛ sɛ wɔyɛ FSH nti, awotwaa anaa mmadwoa no ntumi nyɛ adwuma yiye. Wɔfrɛ saa tebea yi hypogonadotropic-hypogonadism .
Ebia eyi fi:
- Pituitary gland haw ahorow: Nneɛma te sɛ pituitary adenomas betumi ama ntini no ayɛ den anaasɛ asɛe, na ebetumi asɛe hormone a wɔyɛ no.
- Hypothalamic haw ahorow: Awosu mu tebea horow a ɛntaa nsi te sɛ Kallmann syndrome betumi ama hormone GnRH a wɔyɛ no so atew, na ebetumi ama FSH dodow so atew.
Dɛn ne FSH dodow a ɛnteɛ ho sɛnkyerɛnne?
Sɛ́ ebia FSH dodow sua anaasɛ ɛkɔ soro no, sɛnkyerɛnne ahorow no taa te sɛ hypogonadism , i.e., gonads a ɛnyɛ adwuma yiye de. Saa sɛnkyerɛnne ahorow yi gu ahorow wɔ mfe a obi adi ne ɔbarima ne ɔbea nna mu.
| Hokwan / Onipa | Nsɛnkyerɛnne a wotumi hu |
|---|---|
| Nkokoaa a wɔawo wɔn foforo | - a ɛyɛ ketewaa a ɛnyɛ ne kwan so (Micropenis) . - a enni fam |
| Mmofra a wɔredu wɔn mpanyin afe so | - a enni nufu mu nkɔsoɔ wɔ mmabaa mu - a enni nna anaase ekyerekyere (Amenorrhea) . - a ewo mmarimaa mu no nnye nyini. - a ewo brɛoo wɔ ɔkwan a wɔfa so foro kɔ soro no mu |
| Ɔbarima a wanyin | - a ewo nna ho akɔnnɔ a ɛso tew - a ewo ho dodo - a wontumi nwo, Azospermia - a ewo ho a ewo ho - a ewo nufu mu nyini (Gynecomastia) . - a wotew nipadua ne anim nhwi so |
| Mmea a wɔn mfe akɔ anim | - a ewo nna ho akɔnnɔ a ɛso tew - a ewo ho dodo - a wontumi nwo, ovulation haw - a ɛyɛ hyew - bra a ennye daa anaase bratwa a egyae - a ɛso atew wɔ kokoam beae |
Ɔkwan bɛn so na wɔsusuw FSH dodow?
Wobetumi de mogya mu nhwehwɛmu a ɛnyɛ den asusuw wo FSH dodow . Nea ɛka nhwehwɛmu yi ho no, ebia wo duruyɛfo bɛkamfo akyerɛ sɛ wɔnyɛ hormone nhwehwɛmu afoforo pii na ama woahu wo tebea no ho mfonini a edi mũ.
- Nnuru a ɛma mogya tu (LH) .
- Testosterone a ɛwɔ nipadua no mu
- Estradiol ne/anaasɛ progesterone
Wɔtaa yɛ sɔhwɛ ahorow yi:
- Sɛnea ɛbɛyɛ a wobehu nea ɛde awo a wontumi nwo ba
- Sɛnea ɛbɛyɛ a wobehu ɔhaw ahorow a ɛwɔ awotwaa anaa awotwaa mu
- Sɛnea ɛbɛyɛ a wobehu ɔhaw ahorow a ɛwɔ pituitary gland anaa hypothalamus no mu
- Sɛnea ɛbɛyɛ a wobehu nea ɛde brayɛ a ɛnkɔ so daa ba
- Sɛnea ɛbɛyɛ a wubehu sɛ ebia bratwa rebɛn anaa
- Sɛnea ɛbɛyɛ a wobehu nea ɛde mmadwoa dodow a ɛba fam ba
- Sɛnea ɛbɛyɛ a wobehu nea enti a mmofra mmabunbere kyɛ anaasɛ wɔyɛ ntɛm.
Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?
Sɛ wo anaa wo ba no wɔ tebea horow a edidi so yi mu biako anaa nea ɛboro saa a, ɛho hia yiye sɛ wobɛkɔ oduruyɛfo nkyɛn akɔhwehwɛ afotu.
- Sɛ wowɔ hypogonadism ho sɛnkyerɛnne a yɛaka ho asɛm wɔ atifi hɔ no (te sɛ nna ho akɔnnɔ a ɛso tew, ɔbrɛ a ɛboro so, awo a wontumi nwo).
- Sɛ wo ba no reba mmerantebere ne mmabaabere mu ntɛm anaa akyiri sen sɛnea ɔtaa yɛ a .
- Sɛ worehwɛ akokoaa kwan nanso ɛyɛ den ma wo sɛ wubenyinsɛn a .
FSH yɛ hormone a ɛho hia ma nna mu nkɔso ne awo wɔ yɛn nipadua mu. Esiane sɛ ɛne hormone afoforo pii wɔ abusuabɔ a ɛyɛ nwonwa nti, ɛtɔ mmere bi a ne dodow betumi ayɛ nea ɛnteɛ. Nanso mma ɛnhaw wo wɔ ho. Sɛ wususuw sɛ wo anaa wo ba no wɔ eyi ho haw a, wo ne oduruyɛfo nkasa. Wɔyɛ krado bere nyinaa sɛ wɔbɛboa wo.
Nkrasɛm a Wɔde Kɔ Fie
- FSH yɛ hormone a pituitary gland a ɛwɔ amemene no mu na ɛyɛ na ɛho hia ma mmabunbere, brayɛ kyinhyia, ne mmadwoa a wɔyɛ.
- FSH dodow a ɛkɔ soro taa kyerɛ sɛ ɔhaw bi wɔ awotwaa anaa awotwaa mu, bere a FSH dodow a ɛba fam no betumi akyerɛ sɛ ɔhaw bi wɔ amemene no mu (pituitary/hypothalamus).
- FSH dodow kɔ soro fi awosu mu wɔ mmea mu bere a wɔagyae brayɛ no.
- Mogya mu nhwehwɛmu a ɛnyɛ den nkutoo ne nea ɛsɛ sɛ wuhu fa wo FSH dodow ho, nanso mmɔ mmɔden sɛ w’ankasa wobɛkyerɛ nea efi mu ba no ase.
- Bere nyinaa wo ne wo duruyɛfo nsusuw nea ebefi w’amanneɛbɔ no mu aba ne anammɔn biara a ɛsɛ sɛ wugyina so tu ho.
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