Glucagon a Wobɛte Ase: Sɛnea Ɛboa ma Wodi Wo Mogya Mu Asikre So | Nirogi Lanka na ɔkyerɛwee

So woasusuw sɛnea wo nipadua ma asikre dodow a ɛwɔ wo mogya mu no kari pɛ pɛpɛɛpɛ ho pɛn? Ade titiriw a ɛyɛ adwuma wɔ saa adeyɛ yi mu ne ade bi a wɔfrɛ no glucagon. Fa no sɛ ɔbran ketewaa bi a ɔwɔ wo nhyehyɛe no mu, a ɔreyɛ adwuma a ɔmmrɛ de ahwɛ ahu sɛ asikre a ɛwɔ wo mogya mu no nkɔ fam dodo. Ɛnnɛ, yɛrebɛhwehwɛ sɛnea glucagon yɛ adwuma pɛpɛɛpɛ, wɔ nsɛm a emu da hɔ na ɛnyɛ den mu, wɔ Nirogi Lanka ha.

Dɛn ne Glucagon?

Sɛ yɛbɛka no tiawa a, glucagon yɛ abɔde mu hormone a w’ankasa wo nipadua na ɛyɛ . Ne titiriw no, alpha nkwammoaa a ɛwɔ wo dwensɔtwaa mu no na ɛbɔ. Wo nipadua no gyae glucagon bere biara a wo mogya mu glucose (asikre) dodow so tew—te sɛ bere a woadi mmuada akyɛ, apɔw-mu-teɛteɛ a emu yɛ den, anaa bere a woadi aduan a protein pii wom akyi.

Fa no sɛ glucose ne wo nipadua mu pɛtro fibea titiriw, a wunya fi carbohydrates a ɛwɔ aduan a wudi mu no mu. Te sɛ pɛtro a wɔde yɛ kar no, saa glucose yi ma ahoɔden a ɛho hia a ehia na ama w’akwaa, wo ntini, ne wo ntini ahorow ayɛ adwuma. Wo nipadua no kari pɛ a ɛyɛ den na ɛyɛ mmerɛw na ama asikre dodow yi akɔ so ayɛ nea ɛfata; sɛ ɛkɔ soro dodo anaasɛ ɛkɔ fam dodo a, ebetumi de akwahosan ho nsɛnnennen ahorow aba.

Glucagon Injections ne Nnuru a Wɔde Petepete Anom

Glucagon a wo nipadua no yɛ akyi no, nneɛma bi wɔ hɔ a wɔde nsa ayɛ a wobetumi anya sɛ nnuru a wɔde twitwiw hwene mu anaasɛ nnuru a wɔde petepete hwene mu a ɛyɛ dry. Ebia woahu sɛ wɔde eyinom di dwuma, titiriw nnipa a wɔwɔ asikreyare a ɛto so 1 , sɛ aduru a egye ntɛmpɛ a wɔde sa asikre a ɛba fam kɛse (asikre a ɛba mogya mu a asiane wom). Sɛ wɔde ma a, saa glucagon yi yɛ adwuma denam wo mmerɛbo a ɛkanyan no ma ɛma glucose a wɔakora so no kɔ wo mogya mu no so, na ɛma wo asikre dodow ‘nya nkɔanim’ a egye nkwa wɔ ɔkwan a etu mpɔn so.

Ɔkwan Bɛn so na Glucagon Ka Wo Nipadua?

Sɛ wo dwensɔtwaa reyɛ adwuma yiye a, ɛde ahwɛyiye siesie wo mogya mu glucose denam nkwaadɔm atitiriw abien so: glucagon ne insulin . Sɛ asikre dodow a ɛwɔ wo mogya mu fi ase so tew dodo (hypoglycemia) a, wo dwensɔtwaa no gyae glucagon pii ma ɛsan de dodow no san kɔ soro denam akwan horow pii so:

• Nea edi kan no, glucagon tu kwan kɔ wo mmerɛbo mu na ɛdannan glucose a wɔakora so—a wɔfrɛ no glycogen —ma ɛbɛyɛ nea wotumi de di dwuma, na afei mmerɛbo no yi kɔ wo mogya mu.
• Nea ɛto so abien no, glucagon ma wo mmerɛbo no nnyae glucose a wɔkora so, na ɛhwɛ hu sɛ pii bɛkɔ so atra wo mogya mu.
• Nea ɛto so abiɛsa no, glucagon boa wo nipadua ma ɛyɛ glucose foforo a efi mmeae afoforo te sɛ amino acids .

Kae sɛ eyi te sɛ seesaw: sɛ asikre a ɛwɔ mogya mu sua a, glucagon yɛ adwuma; sɛ asikre a ɛwɔ mogya mu dɔɔso a, insulin di anim!

Tebea Bɛn na Ɛka Glucagon Dwumadi?

Sɛ ɛyɛ den ma wo nipadua sɛ ɛbɛhwɛ glucagon so yiye a, ebetumi de akwahosan ho nsɛnnennen aba.

Sɛ wowɔ asikreyare a, ebia wo nipadua bɛpere sɛ ebeyi glucagon a ɛdɔɔso afi mu bere a asikre a ɛwɔ wo mogya mu no so tew no. Eyi de wo to aasiane kɛse a ɛwɔ hɔ sɛ wobɛtaa asikre a ɛkɔ fam anaasɛ emu yɛ den , titiriw sɛ worenom insulin anaa nnuru bi te sɛ sulfonylureas a.

Wɔ nnipa bi a wɔwɔ asikreyare a ɛto so abien mu no, ebia glucagon dodow bɛkɔ soro ankasa asen sɛnea ɛte daa, na ebetumi ama asikre a ɛwɔ mogya mu akɔ soro.

Bere a nsɛm a ɛfa glucagon a wɔyɛ wɔ asikreyare akyi ho ntaa nsi no, ebetumi aba esiane:

• Pancreatitis: Sɛ dwensɔtwaa mu ɔfe a enni sabea ma asikreyare ba a, ebia wubehyia glucagon a enni wo mu, na ɛbɛma asiane a ɛwɔ hɔ sɛ asikre a ɛwɔ wo mogya mu no bɛkɔ fam no ayɛ kɛse.
• Glucagonoma: Akisikuru a ɛntaa nsi koraa wɔ dwensɔtwaa mu a ɛma glucagon dɔɔso dodo, na ɛma asikre kɔ soro wɔ mogya mu, honam ani akisikuru pɔtee bi, na ɛma obi mu duru so tew.
• Multiple Endocrine Neoplasia (MEN): Awosu mu tebea a ɛntaa nsi a ntini pii a ɛwɔ wo endocrine nhyehyɛe mu no nya akisikuru, a ebia dwensɔtwaa no ka ho.
• Pancreatectomy: Sɛ wɔyɛ oprehyɛn yi wo dwensɔtwaa no fã bi anaa ne nyinaa a, ebia wobɛhwere nkwammoaa a ɛma glucagon ne insulin nyinaa no.

Nsɛm a Ɛfa Glucagon Ho Ho Nsɛnkyerɛnne

Sɛnea yɛaka ho asɛm no, glucagon a ɛnteɛ betumi ama asikre a ɛwɔ mogya mu akɔ fam (asikre a ɛwɔ mogya mu a ɛba fam) anaasɛ asikre a ɛkɔ soro (asikre a ɛwɔ mogya mu a ɛkɔ soro). Sɛnea ebia wubehu saa sɛnkyerɛnne ahorow yi ni.

Hypoglycemia (Mogya Mu Asikre a Ɛba Fam) Ho Nsɛnkyerɛnne .

Sɛ wo anaa wo dɔfo bi di asikreyare ho dwuma a, ɛho hia sɛ wuhu sɛnkyerɛnne ahorow a ɛkyerɛ sɛ asikre a ɛwɔ wo mogya mu no so atew. Ebia mpofirim ara wote nka sɛ wo ho wosow, wo ho fifiri, anaa wo ho dwiriw wo, na ɛbɛyɛ den ama wo sɛ wobɛkasa anaa wode w’adwene besi biribi so. Eyi betumi ayɛ asikre a ɛwɔ mogya mu a ɛba fam ho sɛnkyerɛnne.

Nsɛnkyerɛnne a ɛtaa ba no bi ne:

• Wosow anaasɛ wosow
• Fifiri ne awɔw a wɔte nka
• Adwene a ɛyɛ basaa anaasɛ ne ti a ɛyɛ hare
• Koma a ɛbɔ ntɛmntɛm
• Ɔkɔm a ɛba mpofirim
• Adwene a ɛyɛ basaa anaasɛ ɛyɛ den sɛ wode w’adwene besi biribi so

Nea ɛho hia: Sɛ wuhu saa sɛnkyerɛnne ahorow yi a, ɛho hia sɛ wudi biribi a asikre anaa carbohydrates wom ntɛm ara . Eyi boa ma asikre dodow a ɛwɔ wo mogya mu no san ba. Sɛ wuhu sɛ eyi taa kɔ so a, ɛsɛ sɛ wokɔ wo duruyɛfo nkyɛn a wontwentwɛn wo nan ase.

Mogya Mu Asikre a Ɛdɔɔso (Hyperglycemia) Ho Nsɛnkyerɛnne .

Mpɛn pii no, insulin a enni mogya mu asikre a ɛkɔ soro (hyperglycemia) na ɛde ba, sen sɛ ɛbɛyɛ glucagon ho asɛm titiriw. Nanso, nsɛm a ɛntaa nsi a ɛfa glucagon ho nso betumi ama asikre a ɛwɔ mogya mu akɔ soro. Nsɛnkyerɛnne a edi kan no bi ne:

• Sukɔm a ɛkɔ soro ne/anaasɛ ɔkɔm a ɛkɔ so daa
• Anisoadehu a ɛyɛ kusuu
• Nsu a wɔtaa tow
• Ti a ɛyɛ yaw

Sɛ worehyia saa sɛnkyerɛnne ahorow yi a, ɛho hia yiye sɛ wobɛkɔ akwahosan ho ɔbenfo nkyɛn.

Sɔhwɛ bɛn na wɔde hwɛ Glucagon dodow?

Sɛ woda sɛnkyerɛnne ahorow bi adi a, wo duruyɛfo betumi ahyɛ sɛ wɔnyɛ wo mogya mu nhwehwɛmu mfa nhwɛ sɛnea wo glucagon te. Wɔ saa adeyɛ yi mu no, oduruyɛfo anaa ɔyarehwɛfo de ade bi bɛgye mogya afi ntini bi mu, na afei wɔde akɔ aduruyɛdan mu ma wɔayɛ mu nhwehwɛmu.

Dɛn ne Glucagon dodow a ɛfata?

Mpɛn pii no, glucagon dodow a ɛfata wɔ wo mogya mu no yɛ picogram 50 kosi 100 wɔ mililita biara mu (pg/mL) . Picogram yɛ gram nkyem ɔpepepem biako—a ɛyɛ simma kakraa bi ankasa!

Ma ɛntra w’adwenem sɛ saa nkyerɛkyerɛmu ahorow yi betumi ayɛ soronko kakra wɔ aduruyɛdan ahorow mu. Bio nso, bere tenten a wode adi mmuada ne asikre dodow a wowɔ wɔ wo mogya mu mprempren bere a wɔreyɛ nhwehwɛmu no betumi anya nea ebefi mu aba no so nkɛntɛnso. Enti, bere nyinaa fa nea efi mu ba no toto reference ranges a wɔde ama wɔ wo lab amanneɛbɔ pɔtee no so no ho . Sɛ wowɔ nsɛmmisa bi a, wo ne wo duruyɛfo a ɔwɔ Nirogi Lanka nsusuw ho.

Bere bɛn na ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn fa wo Glucagon dodow ho?

Sɛ wowɔ asikreyare na wotaa nya asikre a ɛba wo mogya mu anaasɛ ɛkɔ soro a, ɛho hia sɛ wokɔ wo duruyɛfo nkyɛn. Bere a wɔntaa nhwɛ glucagon dodow mu mma obiara a ɔwɔ asikreyare no, ebia ebehia sɛ wɔyɛ nsakrae wɔ wo asikreyare ho nhyehyɛe a wode bedi dwuma no mu na ama nsakrae ahorow yi ayɛ ketewaa bi.

Ɛwom sɛ nsɛm afoforo a ɛfa glucagon ho ntaa mma de, nanso sɛ worehu sɛnkyerɛnne ahorow a, ɛho hia sɛ wubehu nea ɛde ba. Fa bere nyinaa di kan sɛ wo ne w’akwahosan ho ɔyaresafo bɛkɔ akɔhwɛ.

Nsonsonoe bɛn na ɛda Glucagon ne Glycogen ntam?

Saa abien yi yɛ soronko. Glycogen yɛ glucose (asikre) a wɔkora so. Yɛn nipadua titiriw na ɛkora glycogen so wɔ mmerɛbo ne ntini mu.

Glucagon yɛ hormone a ɛma nipadua no yɛ adwuma. Ɛyɛ adwuma sɛ sɛnkyerɛnne kwan so ade, na ɛka kyerɛ mmerɛbo no sɛ ɔnsakra glycogen a wɔakora so no nsan nkɔ glucose mu, na afei ɛkɔ mogya no mu na ama wo nipadua no anya ahoɔden.

Dɛn na ɛba Glucagon so bere a woredi mmuada?

Sɛ woredi mmuada a, glucagon ho hia kɛse na ama asikre a ɛwɔ wo mogya mu no ankɔ fam dodo, efisɛ wo nipadua no nnya glucose mfi aduan mu.

Wɔ mmuadadi bere tenten mu no, glucagon kanyan glucose a efi nneɛma a ɛnyɛ carbohydrate te sɛ srade, amino acid, ne protein mu ba. Wɔfrɛ saa adeyɛ yi gluconeogenesis .

Nkrasɛm a Etwa To a Wɔde Kɔ Fie

Sɛnea wubetumi ahu no, glucagon yɛ hormone a ɛho hia a ɛyɛ adwuma wɔ akyi na ama asikre a ɛwɔ mogya mu no akɔ so ayɛ yiye. Sɛ wunni asikreyare a, glucagon ho haw ahorow ntaa mma koraa.

Nanso, sɛ wotaa hu sɛnkyerɛnne ahorow a ɛkyerɛ sɛ asikre a ɛwɔ wo mogya mu no sua anaa ɛdɔɔso a, yɛsrɛ wo kɔ wo duruyɛfo nkyɛn. Wobetumi ahu nea ɛde ba no na wɔakyerɛw ayaresa a ɛho hia. W’akwahosan a wode bedi kan ne ade a ɛho hia sen biara a wubetumi ayɛ.

Nsɛmfua titiriw: glucagon, asikre a ɛwɔ mogya mu, asikre a ɛba fam, asikre a ɛkɔ soro, asikreyare, dwensɔtwaa, hormone