Momma yensua Human Growth Hormone (HGH) ho ade wɔ nsɛm a ɛnyɛ den mu.

So wote nka sɛ wo ba no nnyin tenten sɛnea ɛsɛ sɛ wɔyɛ no? Anaasɛ wote nka bere nyinaa sɛ woabrɛ na woayɛ mmerɛw? Ebia nea enti a ɛte saa ne nnuru ketewaa bi a ɔbɔ wo nipadua mu. Wɔfrɛ hormone a ɛte saa biako a ɛho hia ma yɛn nipadua nyin ne nneɛma afoforo pii . Yɛfrɛ no HGH (Human Growth Hormone) tiawa. Ebinom nso frɛ no somatotropin . Enti ɛnnɛ, momma yɛnka saa HGH yi ho asɛm nkɔ akyiri, tiawa koraa.

Dɛn ne HGH? Ɔkwan bɛn so na wɔyɛ wɔ yɛn nipadua mu?

Sɛ yɛbɛka no tiawa a, HGH yɛ abɔde mu hormone a yɛn nipadua yɛ. Ntini ketewaa bi a ɛwɔ yɛn amemene no ase pɛɛ, a ne kɛse bɛyɛ sɛ dompe ketewaa bi na ɛyɛ. Yɛfrɛ no pituitary gland . Saa HGH hormone yi ka yɛn nipadua no afã horow pii. Ɛho hia titiriw ma mmofra nyin . HGH boa kɛse wɔ nneɛma te sɛ wo ba a wobɛma ayɛ tenten ne ne nnompe a wobɛma ayɛ den mu.

Nanso, sɛ yenyin pɛ, kyerɛ sɛ, bere a yɛn nnompe (epiphyses) mu mprɛte a enyin no atoto akyi no, HGH mma yɛnyɛ tenten bio. Nanso ɛnyɛ ɛno nkutoo ne nea HGH yɛ. Sɛ yɛnyinyin mpo a, HGH boa ma yɛn nipadua no yɛ nea ɛfata na ɛma yɛn nipadua mu nneɛma a ɛsakra no kɔ so yɛ adwuma yiye. Saa nipadua mu nneɛma a ɛsakra yi na ɛma aduan a yedi no dan ahoɔden. HGH nso boa ma yɛn mogya mu asikre (glucose) dodow kɔ soro kodu baabi.

Hormone yɛ nnuru a ɛwɔ yɛn nipadua mu. Wɔyɛ wɔn ade te sɛ abɔfo. Wɔnam mogya no mu na wɔka nea ɛsɛ sɛ yɛyɛ ne bere a ɛsɛ sɛ yɛyɛ kyerɛ yɛn akwaa, ntini, ne ntini afoforo. Nkwammoaa yi bɛboro 50 na ɛwɔ yɛn nipadua mu!

Pituitary gland a madi kan aka ho asɛm no wɔ amemene no ase, wɔ hypothalamus ase . Saa hypothalamus yi na ɛhwɛ nneɛma pii te sɛ yɛn mogya mmoroso, yɛn koma bɔ, yɛn nipadua mu hyew, ne yɛn aduan mu. Enti, saa hypothalamus yi ne nea ɛka kyerɛ pituitary gland no sɛ onnyi HGH. Wɔfrɛ hormone bi a ɛboa ma wɔyɛ saa no GHRH (hormone a ɛma nipadua no nyin) . Afei nso, hormone foforo (somatostatin) fi hypothalamus mu na ɛma HGH a ɛba no gyae. Eyi ne ɔkwan a wɔfa so di HGH so.

Ɛtɔ mmere bi a nnuruyɛfo de HGH a wɔayɛ no saa di dwuma de sa nyarewa bi. Nanso kae sɛ, mfa HGH a wɔayɛ no foforo nni dwuma da a oduruyɛfo nkyerɛw wo krataa.

Nneɛma bɛn na ɛka HGH a wɔde sie no?

Mpɛn pii no, yɛn pituitary gland no gyae HGH kakraa bi da mũ no nyinaa, a wɔfrɛ no pulses . Nnuru abien a efi hypothalamus mu a wɔfrɛ no GHRH ne somatostatin titiriw na edi eyi so.

Ɛnyɛ ɛno nko, na mmom hormone afoforo nso ka ho. Nhwɛsoɔ,Insulin-like growth factor 1 (IGF-1) ma HGH a wɔyɛ no so tew, bere a hormone te sɛ thyroxine , glucocorticoids , ne ghrelin ma HGH a wɔayi no adi no yɛ kɛse.

IGF-1 a yɛn mmerɛbo no yi no yɛ ade titiriw a efi HGH dwumadi mu ba. Saa IGF-1 yi na ɛhwɛ HGH a wɔyɛ boro so no so. Ɛne sɛ, HGH ma wɔyɛ IGF-1, na IGF-1 a wɔyɛ no san brɛ HGH a wɔyɛ no ase. Ɛte sɛ kyinhyia.

Wɔ obi a ɔwɔ apɔwmuden mu no, asikre a ɛkɔ soro wɔ mogya mu (hyperglycemia) na esiw HGH a ɛba no ano . Nea ɛka ho no, nneɛma te sɛ nna, adwennwen, apɔw-mu-teɛteɛ, asikre a ɛba fam wɔ mogya mu (hypoglycemia) , ne amino acids na ɛkanyan HGH a ɛba no.

Dɛn ne dwumadi atitiriw a HGH hormone no yɛ?

HGH wɔ dwumadi atitiriw abien:

1. Onyin a wɔkanyan (titiriw wɔ mmofra mu) .

2. Ɛka nipadua mu nneɛma a ɛsakra (ɔkwan a yɛfa so dan aduan a yedi no ma ɛbɛyɛ ahoɔden) .

HGH ne nkɔso

HGH boa yɛn nipadua mu ntini ne akwaa biara ma enyin. Nanso agye din kɛse sɛ ɛboa ma ntini ne nnompe nyin. Eyi ho hia titiriw wɔ mmerantebere ne mmabaabere mu. Nkwammoaa a wɔfrɛ no chondrocytes a ɛwɔ nnompe mu ne osteoblasts a ɛwɔ nnompe mu no nya nsɛnkyerɛnne fi HGH hɔ sɛ ɛbɛpaapae na anyin.

Nanso, sɛnea madi kan aka no, HGH mma ne sorokɔ nkɔ soro bere a abofra nnompe mu nyin mprɛte (epiphyses) no atoto akyi. Mmom no, HGH boa ma nipadua no yɛ nea ɛfata wɔ nkwa nna nyinaa mu.

HGH ne nipadua mu nneɛma a ɛsakra

Metabolism yɛ nnuru a ɛma aduan a yedi no dan ahoɔden. Yɛn nipadua mu nkwammoaa biara hia ahoɔden na ama ayɛ adwuma yiye.

HGH ka nipadua mu nneɛma a ɛsakra titiriw denam IGF-1 a ɛma ɛyɛ kɛse so, na ɛsakra ɔkwan a ɛfa so ka yɛn nipadua mu nkwammoaa no. IGF-1 yɛ hormone a ne nhyehyɛe te sɛ insulin . Insulin yɛ hormone a ɛho hia a yɛn dwensɔtwaa yɛ a ɛma asikre (glucose) dodow a ɛwɔ mogya mu no so tew. IGF-1 nso tumi ma asikre a ɛwɔ mogya mu no so tew.

Mpɛn pii no, yɛn nipadua no de ahwɛyiye hwɛ glucose dodow a ɛwɔ yɛn mogya mu no so. Mogya mu glucose, anaa asikre, ne asikre titiriw a ɛwɔ yɛn mogya mu. Yenya fi nnuan a carbohydrate wom a yedi no mu. Saa asikre yi na ɛma yɛn akwaa, yɛn ntini, ne yɛn ntini ahorow no nya ahoɔden.

Insulin ne hormone titiriw a ɛma asikre a ɛwɔ mogya mu no so tew bere a ɛdɔɔso no. Na hormone glucagon ma asikre a ɛwɔ mogya mu no yɛ kɛse bere a ɛba fam no. Nanso, HGH taa ma asikre a ɛwɔ mogya mu no kɔ soro bere a ɛba fam no. Mmom,Sɛ HGH dodow a ɛwɔ wo nipadua mu no kɔ soro dodo a, ebetumi asiw insulin no dwumadi kwan na ama asikre dodow a ɛwɔ wo mogya mu no akɔ soro.

So HGH ma wo tenten ampa?

Yiw, HGH betumi ama mmofra tenten akɔ soro. Nanso ɛno yɛ ansa na mprɛte a ɛma wonyin wɔ wɔn nnompe mu no bɛka abom. HGH ntumi mma wonyɛ tenten bere a onyin mprɛte no abɔ awie no. Mmom no, bere a woadu wo tenten a ɛsen biara no akyi no, HGH boa ma wo nipadua no nhyehyɛe ne ne nipadua mu nneɛma a ɛsakra no kɔ so tra hɔ.

Dɛn ne HGH dodow a ɛfata?

Sɛnea madi kan aka no, pituitary gland no gyae HGH wɔ mpaapaemu mu da mũ no nyinaa. Saa dodow yi gu ahorow gyina da no mu bere, mfe a obi adi, ne ɔbarima ne ɔbea nna so. Enti, mogya mu nhwehwɛmu biako pɛ a wɔde susuw HGH no ho nni mfaso kɛse mfa nhu tebea bi. Mmom no, nnuruyɛfo nam nhwehwɛmu titiriw (nsɔhwɛ a wɔde kanyan anaasɛ wɔde siw ano) so hwɛ HGH dodow.

HGH dodow a ɛyɛ daa no te sɛ nea edidi so yi:

• Mmarima a wɔanyinyin: Nanogram 0.4 kosi 10 wɔ mililita biara mu (ng/mL) .
• Mmea a wɔanyinyin: Nanogram 1 kosi 14 wɔ mililita biara mu (ng/mL) .
• Mmofra: Nanogram 10 kosi 50 wɔ mililita biara mu (ng/mL) .

Nanso kae sɛ, saa gyinapɛn ahorow yi betumi ayɛ soronko kakra wɔ lab biara mu. Enti fa toto range a ɛyɛ daa a ɛwɔ wo lab amanneɛbɔ so no ho. Sɛ wowɔ biribi a ɛhaw wo a, hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa.

Sɛ HGH dodow so tew a, dɛn na ɛba? (Nkwammoaa a Ɛma Onyin a Ɛho Nni Mu) .

Sɛ HGH dodow sua sen sɛnea ɛte daa a, yɛfrɛ no Growth Hormone Deficiency . Mpɛn pii no, ɔhaw bi anaasɛ pituitary gland no sɛe na ɛde eyi ba. Eyi betumi ama obi anya tebea bi a wɔfrɛ no hypopituitarism . Eyi kyerɛ sɛ hormone biako anaa nea ɛboro saa a pituitary gland no yɛ no so tew. HGH nso yɛ hormone a ebetumi aka no wɔ saa kwan yi so.

Saa HGH a enni hɔ yi ka mpanyimfo ne mmofra wɔ akwan horow so.

Sɛ HGH dodow so tew wɔ mpanyimfo mu a:

Sɛ ɔpanyin bi HGH dodow so tew a, ɔhaw ahorow a edidi so yi betumi aba:

• Anigye ne abotɔyam a obi nya wɔ asetra mu a ɛso tew.
• Nipadua mu srade a ɛkɔ soro.
• Asiane a ɛkɔ soro sɛ obi benya komayare.
• Koma, ntini ne nnompe a ɛyɛ mmerɛw.

Wɔ mpanyimfo mu no, tebea yi betumi afi pituitary adenoma (eyi nyɛ kokoram, na mmom akisikuru) anaasɛ pituitary gland/hypothalamus a ɛsɛe.

Sɛ mmofra HGH sua a:

Sɛ abofra bi HGH dodow so tew a, onyin bɛyɛ mmerɛw. Nsɛnkyerɛnne titiriw ne sɛ abofra no tenten kɔ soro nkakrankakra wɔ abofra no awoda a ɛto so abiɛsa akyi. Ɛne sɛ, ennu nsateakwaa 1.4 afe biara. Sɛ nhwɛso no, sɛ ɛte sɛ nea wo ba no yɛ tiaa koraa sen mmofra afoforo a wɔwɔ adesuakuw no mu no a, ɛsɛ sɛ wohaw wo ho.

Bio nso, abofra a HGH nni no nso betumi anya sɛnkyerɛnne ahorow te sɛ:

• Anim a ɛte sɛ nea ɛyɛ ketewa koraa sen ne mfe.
• Nwi nyin a asɛe.
• Mmabunbere a ɛkyɛ.

Wobetumi awo mmofra a wɔwɔ saa tebea yi. Ɛtɔ da bi a wonnim nea ɛde ba (idiopathic), ebetumi afi awosu mu, anaasɛ ebetumi afi pituitary gland a ɛsɛe bere a wɔyem anaa wɔ awo mu. Ɛtɔ mmere bi a, ebetumi afi pituitary gland anaa hypothalamus a ɛsɛe akyiri yi wɔ nkwa nna mu nso mu aba.

Sɛ HGH dodow kɔ soro a, dɛn na ɛba?

Tebea titiriw a ɛbata HGH dodow a ɛkɔ soro sen sɛnea ɛte daa ho ne acromegaly . Ɛsono sɛnea eyi ka mpanyimfo ne mmofra nso. Ɛyɛ tebea a ɛntaa nsi koraa.

Acromegaly a ɛwɔ mpanyimfo mu

Mpɛn pii no mpanyimfo a wɔwɔ acromegaly no nsa ne wɔn nan trɛw anaasɛ ɛho ahonhon na wɔn anim yɛ nsakrae .

Ebia wɔn nnompe a ɛyɛ den ne wɔn mu akwaa akɛse nso. Ɛda adi sɛ wobenya tebea horow te sɛ mogya mmoroso , asikreyare a ɛto so abien, ne komayare. Acromegaly a ɛba no bɛboro 99% fi akisikuru a ɛnyɛ kokoram wɔ pituitary gland a wɔfrɛ no pituitary adenomas . Saa akisikuru yi betumi ama HGH pii aba. Acromegaly taa ba kɛse wɔ mfinimfini mfe akyi, bere a onyin awie no. Enti, mpanyimfo a wɔwɔ acromegaly no nnyin nkɔ akyiri. Mmom no, wɔn nnompe betumi ayɛ den.

Acromegaly (Gigantism) a ɛwɔ mmofra mu

Ɛntaa mma koraa sɛ mmofra betumi anya HGH dodow a ɛkɔ soro ansa na wɔadu wɔn tenten nyinaa ho. Eyi betumi ama nnompe atenten no anyin dodo, na ama mmofra atenten a ɛnyɛ ne kwan so. Wɔfrɛ saa tebea yi mmofra acromegaly . Ɛtɔ mmere bi a wɔfrɛ no gigantism . Sɛ wɔansa mmofra yi yare a, wobetumi anyin akɔ soro anammɔn ason anaa asen saa. Wobetumi nso anya yare no ho sɛnkyerɛnne te sɛ ɔbrɛ, mmabunbere a ɛkyɛ, ne tiyɛ.

Mpɛn pii no, pituitary adenoma nso na ɛde eyi ba.

Ɔkwan bɛn so na wɔsusuw HGH dodow?

Sɛ wo anaa wo ba no wɔ sɛnkyerɛnne ahorow a ɛkyerɛ sɛ ɔwɔ ɔhaw ahorow a ɛfa HGH ho a, wo duruyɛfo betumi ahyɛ sɛ wɔnyɛ mogya mu nhwehwɛmu mpɛn pii mfa nhwɛ sɛnea wo HGH dodow te.

Sɛnea madi kan aka no, pituitary gland no gyae HGH kɔ mogya no mu awia mũ no nyinaa ne bere ne bere mu anadwo. Enti, ɛyɛ den sɛ yɛbɛte tebea no ase yiye denam mogya a wɔbɛfa na wɔahwɛ HGH pɛnkoro pɛ so.

Enti, nnuruyɛfo taa de akwan horow a wɔfrɛ no onyin hormone stimulation ne suppression tests di dwuma de hu tebea horow a HGH a enni nipadua no mu anaasɛ ɛboro so de ba.

Bio nso, wobetumi ayɛ mogya mu nhwehwɛmu de ahwɛ IGF-1 (insulin-like growth factor 1) dodow.

Ɔkwan bɛn so na wɔde HGH di dwuma sɛ aduru?

United States Aduan ne Nnuru Dwumadibea (FDA) apene so sɛ wɔmfa HGH a wɔayɛ no nyɛ adwuma sɛ wɔmfa nsa tebea horow bi. Wobetumi anya saa HGH a wɔayɛ yi bere a oduruyɛfo akyerɛw ama no nkutoo, na wɔde ma sɛ aduru a wɔde twitwiw nipadua no mu.

Wɔkyerɛw HGH ma mmofra wɔ tebea horow a edidi so yi ho:

• Onyin hormone a enni nipadua mu.
• Tebea horow a ɛma obi ho yɛ tiaa, te sɛ asaabo mu yare a enni sabea , Turner syndrome , ne Prader-Willi syndrome .

Wɔkyerɛw HGH ma mpanyimfo ma tebea horow a edidi so yi:

• Onyin hormone a enni nipadua mu.
• Ntini a ɛyera esiane HIV nti .
• Ntini tiaa mu yare .

Nea ɛho hia yiye: Mfa HGH a wɔayɛ no foforo nni dwuma da gye sɛ wo duruyɛfo akyerɛw ama wo.

Dɛn ne nsunsuanso bɔne a efi HGH a wɔayɛ no foforo mu ba?

Nsunsuanso bɔne bi betumi aba bere a wɔde HGH a wɔayɛ no foforo redi dwuma sɛ aduruyɛ no. Eyinom ne:

• Carpal tunnel syndrome (ntini a ɛyɛ mmerɛw wɔ nsateaa mu).
• Insulin a ɛko tia nyarewa a ɛkɔ soro ne/anaasɛ asikreyare a ɛto so abien.
• Nsa ne anan a ɛho ahonhon (edema) .
• Nkwaa ne ntini mu yaw.
• Nufu mu ntini a ɛtrɛw wɔ mmarima mu (gynecomastia) .
• Asiane a ɛkɔ soro sɛ wobenya kokoram ahorow bi.

Nhwehwɛmufo da so ara nni nsɛm a ɛdɔɔso a ɛfa nkɛntɛnso a HGH a wɔde yɛ aduru nya bere tenten no ho.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn wɔ HGH dodow ho?

Sɛ wo anaa wo ba wɔ sɛnkyerɛnne ahorow a ɛfa HGH a enni hɔ anaasɛ ɛboro so ho (sɛ nhwɛso no, onyin brɛoo, akwaa a ɛtrɛw) a, hwɛ hu sɛ wobɛkɔ wo duruyɛfo nkyɛn.

Sɛ wɔresa wo yare dedaw wɔ HGH dodow bi a ɛnteɛ ho a, ɛho hia yiye sɛ wobɛkɔ wo duruyɛfo nkyɛn daa na ama woahwɛ ahu sɛ w’ayaresa no reyɛ adwuma yiye.

HGH yɛ hormone a ano yɛ den a ɛho hia ma nneɛma pii a ɛho hia wɔ yɛn nipadua mu. Ɛtɔ mmere bi a yɛn pituitary gland no tumi yɛ no pii dodo anaasɛ ɛyɛ kakraa bi. Sɛ wo anaa wo ba wɔ saa sɛnkyerɛnne yi bi a, ɛbɛyɛ papa sɛ wo ne oduruyɛfo bɛkasa. Wɔwɔ hɔ sɛ wɔbɛboa wo.

Nkrasɛm a Etwa To a Wɔde Kɔ Fie

Okay, enti yɛkaa HGH ho asɛm pii nnɛ, ɛnte saa? Momma yɛnsan nsusuw ho tiawa:

• HGH yɛ hormone a ɛho hia yiye ma yɛn nyin, titiriw wɔ mmofraase, ne yɛn nipadua mu nneɛma a ɛsakra no.
• Pituitary gland a ɛwɔ yɛn amemene mu no na ɛde eyi ba.
• Sɛ HGH dodow so tew a, ebia mmofra nyin ayɛ mmerɛw, na mpanyimfo nso betumi anya akwahosan ho haw ahorow.
• Sɛ HGH dodow kɔ soro a, tebea horow te sɛ acromegaly betumi aba.Wɔ mmofra fam no, eyi betumi ada adi sɛ kɛseyɛ, a ɛkyerɛ sɛ obi nyin tenten wɔ ɔkwan soronko so.
• Sɛ wususuw sɛ ebia wo anaa wo ba no wɔ HGH ho haw a, ntwentwɛn wo nan ase sɛ wobɛhwehwɛ aduruyɛ mu afotu.
• Mfa HGH a wɔayɛ no foforo nni dwuma da a oduruyɛfo nkyerɛw wo krataa.

Kae sɛ wɔayɛ eyinom nyinaa sɛ wɔde bɛkyerɛkyerɛ wo. Sɛ wowɔ akwahosan ho haw bi a, wo duruyɛfo nkutoo na obetumi de ano aduru a eye sen biara ama wo. Kɔ so nya apɔwmuden!

` Nnipa Onyin Hormone, HGH, Pituitary Gland, Mmofra Nnyin, Ɔsorokɔ a Ɛkɔ soro, Nneɛma a Ɛsakra, Nkwammoaa a Ɛnkari pɛ