Momma yensua kokoram aduru Larotrectinib ho ade.

Sɛ wo duruyɛfo kyerɛw aduru bi a wɔfrɛ no Larotrectinib ma wo anaa obi a wunim no a, ɛyɛ ade a ɛfata sɛ wubenya nsɛmmisa pii wɔ ho. Aduru bɛn na eyi yɛ? Dɛn na ɛbɛba wɔ ho? So nsunsuanso bɔne bi wɔ hɔ? Ebia woresusuw ho. Nha wo ho. Momma yɛnka aduru yi ho asɛm tiawa, wɔ ɔkwan a wubetumi ate ase so.

Dɛn ne Larotrectinib?

Sɛ yɛbɛka no tiawa a, larotrectinib yɛ aduru titiriw bi a esiw kokoram nkwammoaa nyin ano. Wɔfrɛ eyi sɛ ‘ayaresa a wɔde wɔn ani asi so’. Eyi kyerɛ sɛ saa aduru yi kɔ protein pɔtee bi a ɛwɔ kokoram nkwammoaa mu nkutoo so tẽẽ na ɛka, na ɛma saa nkwammoaa no nnyin.

Nanso eyi nyɛ aduru a wɔde ma kokoram ahorow nyinaa. Wɔsɔ wo kokoram nkwammoaa hwɛ sɛ ebia wɔwɔ nkwaadɔm mu nsakrae titiriw bi wɔ awosu mu abɔde bi a wɔfrɛ no NTRK (neurotrophic receptor tyrosine kinase gene fusion) mu anaa . Nnipa a wɔwɔ saa awosu mu nsakrae no nkutoo na wobenya saa aduru yi so mfaso. Enti sɛ wo duruyɛfo akyerɛw saa aduru yi ama wo a, ɛkyerɛ sɛ ɛda adi sɛ wo kokoram no bɛyɛ ho biribi yiye.

Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru

Ansa na wubefi saa aduru yi ase no, ɛho hia yiye sɛ wode w’akwahosan ho nkyerɛkyerɛmu a edi mũ ma wo duruyɛfo. Hwɛ hu sɛ wobɛka nea edidi so yi ho asɛm titiriw akyerɛ wɔn:

Ɔkwan bɛn so na ɛsɛ sɛ mede saa aduru yi di dwuma?

Nea ɛho hia sen biara ne sɛ wobɛnom aduru no sɛnea oduruyɛfo no ka no pɛpɛɛpɛ.

• Fa nsu kuruwa mene saa aduru yi nyinaa .
• Mmu, nsɛe, anaa nwe capsule no.
• Wubetumi anom eyi ansa na woadi anaasɛ woadi awie. Nanso, bɔ mmɔden sɛ wobɛfa bere koro mu da biara da .
• Nea ɛho hia yiye: Mfa aduru yi nka bobe nsu ho da.
• Nnyae w’aduru nom a wunnya wo duruyɛfo afotu.

Sɛ dodow a wɔde ma no kɔ soro (overdose) a, dɛn na ɛsɛ sɛ woyɛ?

Sɛ wususuw sɛ woanom aduru yi dodo a, mma wo ho nnyɛ wo hu. Frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ ntɛm ara . Anaasɛ kɔ ayaresabea a ɛbɛn wo no Emergency Treatment Unit (ETU) .

Na sɛ me werɛ fi sɛ mɛnom m’aduru nso ɛ?

Sɛ wopa dose bi a, fa no bere a woakae ara pɛ. Nanso, sɛ ennu nnɔnhwerew 6 kosi wo dodow a edi hɔ a wobɛma no so a, twa dodow a woayera no so na fa wo dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru abien prɛko pɛ da.

Nneɛma afoforo a ebetumi ne aduru yi adi nkitaho (Nkitahodi) .

Ebia saa aduru yi ne nnuru ne nnuan afoforo bedi nkitaho. Enti, ka biribiara a worenom ho asɛm kyerɛ wo duruyɛfo. Nea ɛka eyi ho ne nnuru a wɔkyerɛw ma, nnuru a wɔtɔn, nnuru a wɔde nhabannuru yɛ, vitamin, ne nnuru a wɔde ka aduan ho. Afei nso, sɛ wonom sigaret anaa wonom nsa a, ka kyerɛ wo duruyɛfo.

Nneɛma bi a ebetumi ne aduru yi adi nkitaho wɔ ase ha.

• Nnuru a wɔde sa HIV anaa AIDS
• Nnuru bi a ekum ɔyare mmoawa (te sɛ clarithromycin) .
• Nnuru a wɔde sa fungal yare (te sɛ ketoconazole) .
• Nnuru a wɔde sa akisikuru (te sɛ carbamazepine, phenytoin) .
• Nnuru a wɔde yɛ komayare bi
• Nnuru a ɛma nipadua no tumi ko tia nyarewa (te sɛ cyclosporine, tacrolimus) .
• Nnuru bi a wɔde ko tia kokoram (chemotherapy) .
• Nnuadewa a wɔfrɛ no St. John’s Wort
• Grapefruit nsu a wɔde yɛ

Nneɛma a ɛsɛ sɛ wususuw ho bere a worenom nnuru no

• Mogya mu nhwehwɛmu: Bere a worenom aduru yi no, wo duruyɛfo bɛhyɛ sɛ wɔnyɛ mogya mu nhwehwɛmu bere ne bere mu de ahwɛ nneɛma te sɛ wo mmerɛbo dwumadi.
• Nnwuma a ɛsɛ sɛ wohwɛ so yiye: Saa aduru yi betumi ama wo ho ayɛ wo yaw, woada, anaasɛ w’adwene atu afra. Enti, kwati nnwuma a ehia sɛ wode w’adwene si so, te sɛ karka anaa mfiri a wode bedi dwuma, kosi sɛ wubehu sɛnea eyi ka wo nipadua no ankasa.
• Nyinsɛn ne nufu a wɔde ma (ɛho hia yiye):
• Mmea: Kwati sɛ wubenyinsɛn bere a worenom aduru yi ne anyɛ yiye koraa no dapɛn biako bere a woagyae aduru no akyi . Sɛ woreyɛ nhyehyɛe anyinsɛn anaa wususuw sɛ woanyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara.
• Mmarima: Kwati sɛ wobɛwo abofra bere a worenom aduru yi ne anyɛ yiye koraa no dapɛn biako bere a woagyae aduru no akyi .
• Kwati sɛ wobɛma wo ba no nufu bere a worenom aduru yi ne dapɛn biako bere a woagyae no.
• Awo: Ebia aduru yi bɛka sɛnea wubetumi awo mma. Sɛ wowɔ nsɛmmisa bi fa eyi ho a, wo ne wo duruyɛfo nkasa.

Nsunsuanso bɔne a aduru no de ba

Te sɛ aduru biara no, eyi betumi anya ɔhaw ahorow. Ebi yɛ nketewa, bere a afoforo nso hwehwɛ sɛ wodi ho dwuma ntɛm ara.

Sɛ wunya sɛnkyerɛnne foforo biara a ɛyɛ soronko a wɔanka ho asɛm wɔ saa nsɛm yi mu a, wo ne wo duruyɛfo nkasa mfa ho nso.