Dɛn ne "Leaky Gut Syndrome"? So wo gut "leaky" ampa?

Ebia woate sɛ nnipa pii reka ‘Leaky Gut’ ho asɛm nnansa yi, ɛnte saa? Ebinom ka sɛ ɛno na ɛde yafunu mu haw ahorow ne nyarewa ahorow mpo ba. Enti dɛn ankasa ne "Leaky Gut Syndrome" yi? So wo gut betumi ayɛ "leaky" ampa? Momma yɛnka eyi ho asɛm tiawa, wɔ ɔkwan a wubetumi ate ase so.

So yɛn gut "leak" ampa? (Intestinal Permeability) .

Sɛ yɛbɛka no tiawa a, obiara dwensɔtwaa tumi fa mu kodu baabi. Ɛne sɛ, yɛn dwensɔtwaa mu ɔfasu te sɛ afiri a wɔde yiyi mu. Wɔayɛ no sɛnea ɛbɛyɛ a ɛbɛtwe nsu ne aduannuru a ɛwɔ aduan a yedi mu na ɛde aka mogya no ho. Eyi yɛ ade a ɛfata. Nanso wɔ nnipa binom mu no, saa permeability yi, kyerɛ sɛ, tumi a nneɛma tumi di akɔneaba no yɛ nea ɛboro so kakra. Nnuruyɛfo frɛ eyi ``Intestinal Permeability`` anaa ``Hypermeability``.

Susuw nea ɛbɛba ho hwɛ sɛ ntokuru a ɛwɔ saa filter yi mu wɔ wo dwensɔtwaa mu no yɛ kɛse kakra a? Afei ɛnyɛ nsu ne aduannuru nko, na mmom nneɛma akɛse a mpɛn pii no ɛrenkɔ mu, ne ebia nneɛma a awuduru wom mpo, befi ase "atutu" anaasɛ akɔ wo mogya mu.

Yɛn dwensɔtwaa a ɛkata so no nyɛ ntini bi kɛkɛ. Ɛyɛ yɛn nipadua mu ahoɔden a ɛko tia nyarewa no fã titiriw . Ɛyɛ adwuma te sɛ ɔfasu a ɛbɔ ho ban a ɛmma mmoawa ne nneɛma a ɛde nyarewa ba, te sɛ mmoawa, ntumi nkɔ nipadua no mu.

Enti dɛn ne saa "Leaky Gut Syndrome" ade yi?

"Leaky Gut Syndrome" yɛ mprempren nsusuwii, nsusuwii hunu . Sɛnea saa nsusuwii yi kyerɛ no, ɛnyɛ sɛ dwensɔtwaa mu nsu a ɛkɔ soro no yɛ aduan mu yare (GI nyarewa) ho sɛnkyerɛnne nko, na mmom ebetumi ayɛ nyarewa afoforo dodow bi a wɔn ankasa sisi no ntini nso .

Saa nsusuwii yi ka sɛ sɛ wo dwensɔtwaa ɔfasu a ɛbɔ wo ho ban yi yɛ mmerɛw a, awuduru betumi akɔ wo mogya mu. Saa awuduru yi betumi ama nipadua no mu ayɛ hyew , na ebetumi ada ne ho adi sɛ nyarewa ahorow.

Nokwarem no, bere a ebia saa nsusuwii yi bɛboa yɛn ma yɛate nyarewa bi a yɛda so ara nnim nea ɛde ba ankasa ase no, wonnya nkyerɛɛ ho adanse koraa wɔ nyansahu mu . Yenim sɛ dwensɔtwaa mu nsu a ɛkɔ nipadua no mu a ɛkɔ soro, anaasɛ "awotwaa a ɛtwetwe" yɛ tebea ankasa. Nanso, adanse a emu da hɔ a ɛdɔɔso da so ara nni hɔ a ɛbɛma wɔahu sɛ ɛyɛ yare biako anaasɛ ɛde nyarewa afoforo ba. Enti, "Leaky Gut Syndrome" nyɛ mprempren aduruyɛ mu nhwehwɛmu a wogye tom.

Nyarewa bɛn na wɔka sɛ ɛne "leaky gut" wɔ abusuabɔ?

Wɔ nyarewa a wɔahu dedaw sɛ ɛne dwensɔtwaa mu nsu a ɛkɔ mu no wɔ abusuabɔ akyi no, nyarewa bi nso wɔ hɔ a wosusuw sɛ ɛne eyi wɔ abusuabɔ, nanso wonnya nkyerɛɛ no ​​yiye.

Nyarewa a ɛne no wɔ abusuabɔ ankasa:

Wɔ nyarewa bi a ɛma obi ho hyehye no ne nea nipadua no tumi ko tia nyarewa, titiriw nea ɛka aduannoa nhyehyɛe no mu no, wɔahu sɛ dwensɔtwaa mu nsu a ɛkɔ nipadua no mu no kɔ soro. Nhwɛsoɔ:

• Yare a Ɛma Ɔyare a Ɛma Ɔyare (IBD) .
• Celiac Yare a Ɛyare

Wɔ nsɛm a ɛte sɛɛ mu no, nyansahufo taa bu dwensɔtwaa mu nsu a ɛkɔ soro no sɛ ɛyɛ yare no ho sɛnkyerɛnne , sen sɛ ɛbɛyɛ nea ɛde ba. Nea enti a ɛte saa ne sɛ yare no ma ɔfe a ɛtra hɔ kyɛ wɔ dwensɔtwaa no mu, na ɛde nkakrankakra ma dwensɔtwaa no mu nneɛma a ɛbɔ ho ban no yɛ mmerɛw bere a bere kɔ so no.

Ɛtɔ mmere bi a, ansa na wɔahu nyarewa yi mpo no, wɔahu sɛ ɛma dwensɔtwaa mu nsu kɔ mu kɛse. Eyi ama ebinom agye adi sɛ ebia saa nsu a ɛtumi fa mu yi yɛ tebea bi a na ɛwɔ hɔ dedaw, anaasɛ ɛno mpo na ɛde yare no ba. Nanso, nyansahufo aka sɛ nsu a ɛtumi fa mu a ɛkɔ soro nkutoo nnɔɔso sɛ ɛde yare no bɛba wɔ nsɛm yi mu. Ebia ɛbɛyɛ yare no ho sɛnkyerɛnne a edi kan .

Nyarewa a wosusuw sɛ ɛne no wɔ abusuabɔ, nanso wonnya nkyerɛe koraa:

Nyarewa afoforo pii wɔ hɔ a wosusuw sɛ "leaky gut syndrome" na ɛde ba. Adwene no ne sɛ awuduru a "ɛtu" fi awotwaa no mu no hyɛn mogya no mu na ɛde ɔfe ba. Nokwarem no, ɔfe a ɛba fam a enni sabea wɔ nipadua no mu no ne nyarewa ahorow bi wɔ abusuabɔ. Nhwɛsoɔ:

• Nkwammoaa mu nyarewa te sɛ kɛseyɛ mmoroso ne asikreyare
• Nkwaa mu yaw (Arthritis) .
• Ɔbrɛ a Enni Sabea
• Akisikuru
• Fibromyalgia a ɛma obi ho yɛ hyew

Nanso, wonnya nhuu nea ɛde fekubɔ yi bae ankasa. Wɔahu sɛ nnipa a wɔwɔ yafunu mu yare (GI) a wonim sɛ ɛma dwensɔtwaa mu nsu a ɛkɔ mu no yɛ kɛse no wɔ awotwaa mu mmoawa pii wɔ wɔn mogya mu. Wɔ tebea horow yi mu no, nneɛma afoforo na ɛde ɔfe ba, nanso saa mmoawa yi nso tumi ma ɔfe no yɛ kɛse. Wɔahu wɔ nnipa a wɔwɔ mmerɛbo mu yare nso mu. Nea enti a ɛte saa ne sɛ mmerɛbo yɛ akwaa bi a ɛne dwensɔtwaa no wɔ abusuabɔ tẽẽ. Saa mmoawa yi tumi fa ntini kɛse bi a efi dwensɔtwaa mu kɔ mmerɛbo mu na ɛboa ma mmerɛbo mu yare ba. Nanso, ɛnyɛ nea ɛde yare no ntini ba ankasa.

Hena na dwensɔtwaa mu nsu a ɛkɔ mu no ka no kɛse?

Sɛ dwensɔtwaa no mu nsu a ɛtumi fa mu no bɛkɔ soro, kyerɛ sɛ, sɛ dwensɔtwaa no mu nneɛma a ɛbɔ ho ban no bɛsɛe a, ɛsɛ sɛ wɔsɛe no nkakrankakra na ɛkɔ so daa . Eyi nyɛ mmerɛw. Wo dwensɔtwaa mu ntini no wɔ nneɛma pii a ɛbɔ wo ho ban. Na, sɛ ɛsɛe bere tiaa bi mpo a, wɔresiesie na wɔresan ayɛ no foforo bere nyinaa. Enti, sɛ ɛbɛma saa ntama yi ayɛ mmerɛw araa ma atumi afa mu a, ɛsɛ sɛ enya nkɛntɛnso kɛse. Ɛno taa kyerɛ sɛ:

• Yare a enni sabea
• Nnuru bi a wɔde di dwuma bere tenten anaa nsa a wɔnom
• Ɛsɛ sɛ ɛyɛ biribi te sɛ mframa a wɔde sa yare .

"Leaky Gut Syndrome" nsusuwii no ne sɛ biribiara a ɛsɛe akyi berɛmo no ntama, sɛ ɔsɛe no kɔ so a, ebetumi ama dwensɔtwaa no akɔ mu. Enti, saa nsusuwii yi ka sɛ nneɛma a ɛkɔ so da biara da te sɛ aduan a wodi ne adwennwen betumi ama dwensɔtwaa no mu nneɛma ayɛ mmerɛw nkakrankakra, na awiei koraa no ama atumi akɔ mu. Nanso, nyansahufo nnya nhuu eyi. Nanso, wogye tom sɛ saa nneɛma a ɛkɔ so da biara da yi betumi ama awotwaa no mu ayɛ hyew na ama woanya ``GI`` sɛnkyerɛnne a ɛnyɛ dɛ.

Ɔkwan bɛn so na "leaky gut" ka nipadua no?

Nneɛma abien a ɛsono emu biara. Nnipa pii a wosusuw sɛ wɔwɔ "leaky gut" no nya yafunu mu (GI) sɛnkyerɛnne a ɛtaa ba te sɛ yafunu mu yaw, aduan a wɔte nka, ɔfe, ne aduan mu haw ahorow. Saa sɛnkyerɛnne ahorow yi abu so yiye, na ebetumi de nneɛma pii aba. Na saa nneɛma a ɛde ba no pii nso betumi asɛe wo dwensɔtwaa mu ntini. Enti, enhia sɛ wunya "leaky gut" ansa na woanya nea efi mu ba no mu osuahu.

Ɔsɛe a ɛba dwensɔtwaa no mu:

Sɛ wo dwensɔtwaa no resɛe bere nyinaa a, awiei koraa no, entumi mmɔ ne ho ban mfi nnuru, akisikuru, anaa mmoawa a wɔwɔ dwensɔtwaa no mu ho. Eyi ne nea ɛba wɔ tebea horow te sɛ peptic ulcer yare ne dwensɔtwaa nketewa mu mmoawa a enyin dodo (SIBO ) mu. Sɛ mmoawa bɔne dɔɔso sen mmoawa pa a wɔtaa ma wɔhyɛ wɔn so no a, acid ne enzyme ahorow a ɛwɔ awotwaa no mu no mu yɛ den sen nsu a ɛbɔ wɔn ho ban a ɛtaa ma wɔhyɛ wɔn so no.

Sɛ wo dwensɔtwaa no mu nneɛma sɛe a, ebetumi aka wo aduan, wo nipadua mu ahoɔden a ɛko tia nyarewa, ne sɛnea wote nka wɔ wo dwensɔtwaa ho . Wɔ tebea horow bi mu mpo no, ebetumi ama dwensɔtwaa no mu nsu a ɛkɔ mu no akɔ soro. Nanso, enhia sɛ ɛkɔ akyiri saa na ama woate nka sɛ wo ho nyɛ wo dɛ. Sɛ wowɔ `(GI)` sɛnkyerɛnne ahorow a, ɛtaa fa tebea bi a ɛwɔ ase a ɛresɛe wo dwensɔtwaa mu ntini wɔ nea edi kan no mu. `(GI)` nyarewa pii wɔ sɛnkyerɛnne a ɛte saa ara.

Intestinal Nsuo a Ɛtumi Fa Nsuo Mu:

Nnipa binom wɔ awotwaa a ɛretu ankasa. Nanso ebetumi ayɛ den sɛ wobehu nsonsonoe a ɛda saa dwensɔtwaa a ɛretu yi ho sɛnkyerɛnne ahorow ne ɔhyew tebea bi a ɛda adi ho sɛnkyerɛnne ahorow ntam. Sɛ wo dwensɔtwaa mu ntini no sɛe a, mmoawa a wɔte wo dwensɔtwaa mu no betumi atwam wɔ akwanside a ɛbɔ wo ho ban yi ho na wɔakɔ wo nipadua mu. Nanso yennya nhui sɛ ebia eyi de ɔsɛe kɛse bi ba sen opira a edi kan no so anaa. Nhwehwɛmu ahorow bi kyerɛ sɛ mmoawa a wofi wo dwensɔtwaa mu kɔ wo mmerɛbo mu no betumi ama mmerɛbo mu yare aba.

Dɛn ne nneɛma atitiriw a ɛde "leaky gut" ba?

Sɛ wo dwensɔtwaa akwanside no asɛe a, ɛbɛyɛ sɛ asɛe kɛse, mpɛn pii no bere tenten. Nneɛma a ɛma awotwaa no tumi fa mu tẽẽ no bi ne:

• Ɔhyew tebea a enni sabea, sɛ nhwɛso no `(IBD)` ne `(Celiac Yare)`.
• Nyarewa afoforo a ɛsɛe dwensɔtwaa, sɛ nhwɛso no `HIV/AIDS` .
• Nnuru a wɔde sa yare ne mframa a wɔde sa yare a ɛsɛe dwensɔtwaa mu ntini no.
• Nsã anaa NSAID ahorow a wɔde di dwuma boro so bere tenten (sɛ nhwɛso no, nnuru a wɔde kum ɛyaw te sɛ aspirin ne ibuprofen) .
• Aduan ho akisikuru yɛ sɛnea nipadua no mu tumi a ɛko tia nyarewa no yɛ n’ade wɔ nnuan bi ho.

Dɛn ne "leaky gut" ho sɛnkyerɛnne?

Nsɛnkyerɛnne pɔtee biara nni hɔ a wobetumi aka tẽẽ sɛ efi dwensɔtwaa mu nsu a ɛkɔ mu kɛse. Nanso esiane sɛ mpɛn pii no, dwensɔtwaa mu nsu a ɛkɔ mu no ba bere a dwensɔtwaa no mu ntini no asɛe akyi nti, wubetumi anya sɛnkyerɛnne ahorow a efi saa ɔsɛe no mu ba. Nhwɛsoɔ:

• Ɔhyew a efi dwensɔtwaa mu akisikuru de ba.
• Tebea a ɛyɛ yaw a ɛma obi ntumi nnya aduan a ɛnam dwensɔtwaa mu ntini a ɛsɛe so.
• Ayamtuo .
• Mframa ne ahurututu a ɛyɛ mmerɛw esiane mmoawa a wɔayam dodo wɔ dwensɔtwaa mu nti.
• Ahoɔden a wɔte nka sɛ ɛba fam esiane tumi a ɛso tew sɛ ɛtwetwe ahoɔden fi aduan mu nti.
• Yafunu mu ntini mu yare a efi mframa a wɔde sa yare mu ba.

Wobɛyɛ dɛn asusuw sɛnea dwensɔtwaa no tumi fa mu?

Mprempren sɔhwɛ biara nni hɔ a wɔahyɛ da ayɛ a ebetumi asusuw sɛnea ayarefo dwensɔtwaa mu tumi fa mu tẽẽ. Eyi yɛ ade biako nti a mprempren wonnye dwensɔtwaa mu nsu a ɛkɔ mu no ntom sɛ aduruyɛ mu nhwehwɛmu. Nanso wɔreyɛ nhwehwɛmu ahorow pii wɔ ayaresabea nhwehwɛmu gyinabea de ahu adanse a ɛkyerɛ sɛ ayarefo dwensɔtwaa tumi fa mu. Saa sɔhwɛ ahorow yi bi ne:

• Nsu mu nhwehwɛmu: Nea ɛka eyi ho ne sɛ wɔbɛma wo asikre a wɔadi afra a ɛsono ne kɛse (a ebinom ntumi nnye dwensɔtwaa no). Afei, wɔsusuw asikre dodow a ɛwɔ wo nsu mu no de hwɛ asikre a atwam wɔ dwensɔtwaa no fasu no mu.
• Mogya mu nhwehwɛmu: Nea ɛka eyi ho ne sɛ wobɛfa wo mogya bi na woahwehwɛ sɛnkyerɛnne ahorow a ɛkyerɛ sɛ ɔyare mmoawa a ɛwɔ dwensɔtwaa mu no wɔ hɔ. Saa sɔhwɛ yi hwehwɛ nnuru pɔtee bi a ɛko tia nyarewa ne biomarkers te sɛ endotoxins.
• Tissue biopsy: Eyi yɛ sɔhwɛ a ɛyɛ den kakra. Wɔde ntini a efi wo dwensɔtwaa mu no nhwɛsode bi gu afiri titiriw bi a wɔfrɛ no ``Ussing chamber.'' Eyi de anyinam ahoɔden di dwuma de susuw sɛnea ions fa dwensɔtwaa no mu akwanside no so. Saa ion a ɛkɔ so susuw yi te sɛ nsu a ɛkɔ.
• Confocal endomicroscopy: Eyi yɛ endoscopy a wɔatu mpɔn.Eyi ma nyansahufo tumi hu wo dwensɔtwaa mu nneɛma a ɛwɔ wo dwensɔtwaa mu no wɔ nsusuwii a ɛkorɔn yiye na wɔma ɛyɛ kɛse. Wɔde nsu titiriw bi (nsu a ɛne ne ho bɔ abira) gu ntini bi mu na sɛ tokuru bi wɔ nea ɛkata wo dwensɔtwaa mu a, wubetumi ahu sɛ ɛretu akɔ wo dwensɔtwaa mu.

Ɔkwan bɛn so na wobɛsa "leaky gut" yare ntɛmntɛm?

Ɔkwan biako pɛ a wobetumi afa so asa “akisikuru a ɛtwetwe,” anaasɛ dwensɔtwaa mu nsu a ɛkɔ soro no ne sɛ wɔbɛsa tebea a ɛde bae a ɛde bae no . Sɛ nhwɛso no, wɔada no adi sɛ ayaresa pɔtee a wɔde sa nyarewa a ɛbata dwensɔtwaa mu nsu a ɛkɔ mu ho te sɛ IBD ne Celiac Yare no siesie dwensɔtwaa mu ntini a ɛwɔ wɔn a yare no aka wɔn no mu.

Nanso, kae sɛ wɔmfaa ayaresa ahorow a wɔde wɔn ani si dwensɔtwaa mu ntini nkutoo so no sa nyarewa yi anaasɛ esiw dwensɔtwaa mu nsu a ɛsan kɔ mu no ano.

Mɛyɛ dɛn ahwɛ me dwensɔtwaa akwahosan so? (Afotu a ɛbɛma yɛn akyi berɛmo ayɛ yiye)

Nyansahufo kɔ so reyɛ nhwehwɛmu wɔ ayaresa ahorow a ebetumi ama dwensɔtwaa no akwahosan ne ahoɔden a ɛwɔ dwensɔtwaa no mu nyinaa atu mpɔn. Ebia saa ayaresa ahorow yi rentumi nni tebea titiriw bi so koraa. Nanso, wobetumi aboa ma nkɛntɛnso a da biara da nneɛma te sɛ aduan a wodi, adwennwen, ne mmoawa a wɔdɔɔso dodo nya wɔ dwensɔtwaa no mu no so atew. Ebia wɔbɛboa nso ama wo ``GI`` sɛnkyerɛnne ahorow no nyinaa afi hɔ. Ayaresa a ɛtete saa no bi ne:

• Probiotics: Wɔreyɛ probiotics ahorow pɔtee bi ho nhwehwɛmu wɔ sɛnea etumi san ma dwensɔtwaa mu akwanside no yɛ adwuma bio no ho. Nanso, mpɛn pii no, probiotics betumi aboa ma dwensɔtwaa no mu ntini no ayɛ yiye denam mmoawa bɔne a wobesiw ano dodo wɔ wo dwensɔtwaa mu, titiriw wɔ dwensɔtwaa ketewa no mu no so.
• Prebiotics: Prebiotics yɛ aduan ma mmoawa pa a wɔwɔ wo dwensɔtwaa mu. Wɔma wɔn aduan na wɔboa wɔn ma wɔko tia mmoawa bɔne no. Eyinom taa yɛ afifide nhama - ade foforo nti a ɛsɛ sɛ wudi wo nnuaba ne nhabannuru!
• Tew srade ne asikre a ɛwɔ w’aduan mu so: Eyinom ma mmoawa bɔne nyin wɔ wo dwensɔtwaa mu. Wɔsan nso yi nneɛma a ɛyɛ den a ɛma aduan mu yɛ hyew (aduan mu emulsifiers) a ebetumi ahyɛ wo dwensɔtwaa abufuw.
• Aduandi: Aduan a ɛkari pɛ a aduannuru akɛse ne aduannuru nketenkete (vitamins ne minerals) a ɛho hia nyinaa ka ho no betumi aboa ma wo dwensɔtwaa mu ayɛ den. Vitamin D ne amino acid L-glutamine betumi aboa titiriw ma woasiesie wo dwensɔtwaa no mu nneɛma.
• Aduane a FODMAP nnim:Eyi yɛ aduan titiriw bi. Wɔkamfo kyerɛ wɔn a wɔwɔ IBS (Irritable Bowel Syndrome) ne wɔn a wɔn ho yɛ den wɔ nnuan bi ho. Nea enti a ɛte saa ne sɛ ɛde nkakrankakra yi nneɛma pii a ɛkanyan aduan a wɔtaa de ba no fi hɔ. Sɛ wudi eyi akyi kakra a, wubetumi ahu nnuan a wo ho yɛ wo hyew bere a woma wo dwensɔtwaa no nkae a ehia na ama wasiesie ne ho no.

Awiei koraa no, nea ɛsɛ sɛ wokae (Take-Home Message) .

Nnipa pii wɔ GI sɛnkyerɛnne ahorow a wontumi nkyerɛkyerɛ mu. Ɛtɔ mmere bi a, ebetumi ayɛ abasamtu kɛse sɛ wubehu nea ɛde ba no. Enti, esiane mmuae a emu da hɔ a enni hɔ nti, "Leaky Gut Syndrome" abɛyɛ ade a agye din a wɔde hu yare a ɛtaa ba ma aduan a ɛnyɛ yiye, ne ebia tebea afoforo pii.

Nanso, nokware dwensɔtwaa mu nsu a ɛkɔ nipadua no mu boro so no yɛ tebea pɔtee bi a emu yɛ den yiye. Ɛnyɛ nea ɛdɔɔso sɛ yɛbɛkyerɛkyerɛ nnipa dodow no ara yare no ho sɛnkyerɛnne mu.

Nnipa dodow no ara wɔ general gut inflammation – tebea a edi leaky gut anim. Ebetumi afi yare pɔtee bi mu aba, anaasɛ ebetumi afi aduan pa a wodi, adwennwen a enni sabea, ne nneɛma afoforo a ɛtaa ba a wɔaka abom.

Nea edi kan no, bɔ mmɔden sɛ wubeyi nneɛma a ɛtaa ba yi afi hɔ. Sɛ ɛno mmoa a, hwɛ hu sɛ wobɛhwehwɛ aduruyɛ mu afotu . Yafunu mu yafunu ho oduruyɛfo a ɔfata betumi aboa wo ma woabu nea ebetumi de wo sɛnkyerɛnne pɔtee no aba no afi hɔ.

` Leaky gut, leaky gut syndrome, leaky gut, dwensɔtwaa mu nsuo a ɛtumi fa mu, aduane mu nhyehyɛeɛ, yafunu a ɛyɛ yaw, gut akwahosan, aduane pa