So lymphocytes a ɛwɔ wo mogya mu no sua? Momma yɛnka lymphopenia ho asɛm!

So wotaa yare? Ɛtɔ mmere bi a, atiridii ketewaa bi mpo gye bere tenten ansa na ne ho atɔ wo, anaasɛ wote nka bere nyinaa sɛ woayɛ mmerɛw? Ade biako nti a saa nneɛma yi ba ne mogya mu nkwammoaa fitaa bi a wɔfrɛ no lymphocytes a ɛte sɛ asraafo a wɔwɔ wo nipadua mu a wɔko tia nyarewa no so tew. Nnuruyɛfo frɛ tebea yi ‘lymphopenia.’ Enti, momma yɛnka eyi ho asɛm nkɔ akyiri kakra nnɛ, ɛnte saa? Ɛnyɛ biribi a ɛsɛ sɛ wosuro, ɛho hia sɛ wohu.

Dɛn ne lymphopenia? Momma yɛnte ase kɛkɛ!

Sɛ yɛbɛka no tiawa a, lymphopenia yɛ tebea a ɛma mogya mu nkwammoaa dodow a ɛwɔ wo mogya mu no sua sen sɛnea ɛte daa. Seesei ebia woresusuw nea ɛyɛ saa lymphocytes yi ho.

Mogya mu nkwammoaa fitaa bi wɔ yɛn mogya mu. Saa mogya mu nkwammoaa fitaa no na ɛbɔ yɛn ho ban denam mmoawa a wɔhyɛn yɛn nipadua mu, kyerɛ sɛ, mmoawa ne mmoawa a wɔde nyarewa ba no so. Ɛte sɛ asraafo dɔm ketewaa bi wɔ yɛn nipadua mu. Saa mogya mu nkwammoaa fitaa yi mu 20% kɔsi 40% yɛ saa nkwammoaa soronko yi a wɔfrɛ no Lymphocytes.

Dwumadi titiriw a saa ntini mu nkwammoaa (Lymphocytes) yi yɛ ne:

• Mmoawa (mmoawa, mmoawa, mmoawa a wɔsɛe nnɔbae, fungi) a wɔhyɛn nipadua no mu a wɔko tia.
• Nkwammoaa a ɛnteɛ te sɛ kokoram nkwammoaa a wɔsɛe no.
• Ɛyɛ adwuma sɛ yɛn nipadua no nipadua mu ahoɔden a ɛko tia nyarewa no fã titiriw.

Nkwammoaa mu nkwammoaa atitiriw abiɛsa na ɛwɔ hɔ:

• T-lymphocytes anaa T-cells: Eyinom boa ma wɔsɛe nkwammoaa a wɔanya ɔyare no ne kokoram nkwammoaa tẽẽ.
• B-lymphocytes anaa B-cells: Eyinom na ɛyɛ nneɛma a ɛko tia nyarewa. Saa nnuru a ɛko tia nyarewa yi boa ma wohu mmoawa na wɔtow hyɛ wɔn so.
• Natural Killer cells (NK cells): Eyinom nso boa ma wɔsɛe nkwammoaa a mmoawa ayɛ wɔn ne kokoram nkwammoaa.

Enti, sɛ lymphocytes dodow so tew, kyerɛ sɛ, sɛ tebea bi a wɔfrɛ no lymphopenia ba a, tumi a yɛn nipadua no tumi ko tia nyarewa no so tew. Afei, nyarewa betumi asɔre ntɛm, na nyarewa a ɛba no betumi agye bere tenten ansa na asa.

Wɔsan frɛ lymphocytopenia ne lymphocytic leukopenia. Leukopenia kyerɛ mogya mu nkwammoaa fitaa a ɛso tew wɔ ɔkwan a ɛkɔ akyiri so. "Lymphocytic" leukopenia kyerɛ lymphocytes a ɛso tew titiriw.

Sɛnea ɛte biara no, ɛsɛ sɛ lymphocytes dodow ahe na ɛwɔ hɔ?

Nkwammoaa a ɛma mogya tu (Lymphocytes) yi dodow gu ahorow wɔ mpanyimfo ne mmofra ntam.

• Wɔ mpanyimfo mu: Mpɛn pii no, ɛsɛ sɛ mogya mu nkwammoaa a ɛma mogya tu 1,000 kosi 4,800 na ɛwɔ mogya microliter biara mu. Lymphopenia yɛ bere a dodow yi nnu 1,000.
• Mmofra de:Mpɛn pii no, mogya mu nkwammoaa a ɛma mogya tu no dodow bɛyɛ 3,000 kosi 9,500 wɔ mogya microliter biara mu. Saa dodow a ɛba fam yi betumi ayɛ soronko a egyina mfe a abofra no adi so. Sɛ nhwɛso no, sɛ abofra a onnii mfe 2 wɔ lymphocyte dodow a ennu 3,000 a, wobu no sɛ lymphopenia.

Saa gyinapɛn ahorow yi betumi ayɛ soronko kakra wɔ lab biara mu, enti ɛbɛyɛ papa sɛ wode bɛtoto gyinapɛn ahorow a ɛwɔ w’amanneɛbɔ no mu no ho.

Dɛn ne sɛnkyerɛnne ahorow a ɛkyerɛ sɛ obi anya lymphopenia?

Nea eye sen biara ne sɛ, sɛ wowɔ lymphopenia nkutoo a ɛkyerɛ sɛ lymphocytes nni mu a, mpɛn pii no wunnya sɛnkyerɛnne biara. Nanso, sɛ yare bi wɔ hɔ a ɛde lymphocyte dodow a ɛba fam ba a, ebia wubenya sɛnkyerɛnne ahorow a ɛfa saa yare no ho. Anaasɛ ebia wotaa nya nyarewa.

Nsɛnkyerɛnne a ebetumi ada adi no bi ne:

• Huraeɛ
• Ɛwa
• Hwene a ɛretu
• Honam ani akisikuru anaa honam ani akisikuru afoforo
• Ntini a ɛma mogya tu a ahonhon
• Nkwaa a ɛho ahonhon
• Ano mu akisikuru
• Aniwa ne honam ani yɛ kɔkɔɔ (Jaundice) .
• Akisikuru a ayɛ kɛse anaasɛ ahurututu mu a ɛyɛ kɛse

Sɛ wowɔ lymphopenia a emu yɛ den a, ebia wubenya nyarewa mpɛn pii, anaasɛ ɔyare mmoawa no betumi agye bere tenten ansa na ayɛ yiye. Nanso, sɛ wowɔ lymphopenia a emu nyɛ den a, ebia worennya yare no ho sɛnkyerɛnne biara.

Dɛn nti na saa lymphocyte dodow yi so tew? Dɛn na ɛde ba?

Nneɛma ahorow betumi ama wo mogya mu nkwammoaa a ɛba fam. Ɛtɔ da bi a, ebia wɔbɛwo wo a wowɔ tebea bi a ɛde saa tebea yi ba. Anaasɛ ebetumi aba akyiri yi wɔ asetra mu. Ɛdenam nea ɛde ba so no, lymphopenia betumi ayɛ nkwa nna nyinaa (ɛyɛ nea enni sabea) anaasɛ ebetumi agyae ara kwa (ɛyɛ den).

Nneɛma atitiriw a ɛde lymphopenia ba no bi ne ɔyare mmoawa, nnuru bi, ne aduannuru a wonnya nni.

1. Esiane Nyarewa Ahorow nti

Nyarewa a mmoawa, mmoawa, mmoawa a wɔsɛe nnɔbae, ne fungi de ba no betumi ama lymphocytes so atew. Nhwɛso kakraa bi ni:

• `HIV` ne `AIDS`
• Influenza (flu) - a ekyere se, wo kasa a wotaa ka mu no, atiridii.
• `COVID-19`
• Hepatitis - a ɛyɛ mmerɛbo mu yareɛ
• Malaria a ɛma obi nya ɔyare mmoawa
• Akisikuru
• Ahurututu mu yare
• Nsanyare a ɛma obi nya nsamanwaw

Sɛ ɔyare mmoawa a ɛte saa ba a, nipadua no mu nkwammoaa a ɛma mogya tu (Lymphocytes) no betumi asɛe de ako atia, anaasɛ wobetumi asiw wɔn a wɔyɛ no ano bere tiaa bi.

2. Esiane Aduandi a Ɛnyɛ Den nti

Eyi ne ade titiriw a ɛde lymphopenia ba wɔ wiase nyinaa. Nya nea ɛdɔɔso fi w’aduan mu.Aduan pa a wonnya nni, anaa vitamin ne nnuru te sɛ vitamin B12, folic acid, anaa zinc a wonnya no betumi aka lymphocytes a wɔyɛ no. Esiane sɛ yɛtra ase a adagyew nnim nti, ɛtɔ mmere bi a yɛmfa yɛn adwene nsi nea yedi so sɛnea ɛsɛ. Sɛ nneɛma a ɛte sɛɛ kɔ so a, tebea horow yi betumi aba.

3. Esiane Tebea horow a wonya fi awo mu nti

Awosu mu nyarewa bi wɔ hɔ a wɔntaa nhu a efi awofo hɔ kɔ mmofra mu. Saa nyarewa yi nso betumi ama lymphocytes so atew. Nhwɛso ahorow bi:

• `Ataxia-telangiectasia a ɛma obi ho yɛ hyew`
• ``Nkwammoaa a ɛko tia nyarewa a ɛtaa ba a ɛsakra''.
• `DiGeorge ɔyare mmoawa`
• ``Nyare a emu yɛ den a ɛka bom a ɛma nipadua no tumi ko tia nyarewa (SCID)''.
• `Wiskott-Aldrich ɔyare mmoawa`

Eyinom yɛ nea emu yɛ den kakra, nanso eyinom yɛ tebea horow a ɛntaa nsi koraa.

4. Esiane Autoimmune Diseases nti

Nyarewa a nipadua no tumi ko tia nyarewa ne bere a yɛn ankasa nipadua mu tumi a ɛko tia nyarewa, nhyehyɛe a ɛbɔ yɛn ho ban fi nyarewa ho no di mfomso tow hyɛ yɛn ankasa nkwammoaa a ɛwɔ apɔwmuden so no. Fa no sɛ, wo nipadua no ahobammɔ nhyehyɛe no kɔ so yɛ basabasa na efi ase ko tia n’ankasa nkwammoaa pa. Ɛno ne nea eyi nyinaa fa ho. Lymphocytes betumi aka nkwammoaa a ɛtow hyɛ wɔn so no ho.

Nyarewa a ɛtete saa no bi:

• Lupus a ɛyɛ hu
• Sarcoidosis a ɛma obi nya ɔyare
• Myasthenia gravis a ɛwɔ nipadua no mu
• Rheumatoid arthritis - a ekyere se nkwaa mu yare

5. Esiane Mogya mu Nyarewa ne Kokoram nti

Te sɛ nkwammoaa afoforo a ɛwɔ mogya no mu no, wɔyɛ lymphocytes wɔ nnompe mu ntini mu. Enti, mogya mu nyarewa ne kokoram a ɛka nnompe mu ntini no betumi asɛe lymphocytes a wɔyɛ no.

• Aplastic anemia - tebea a nnompe mu ntini no ma nkwammoaa kakraa bi ba
• Lymphoma - kokoram a ewo ntini mu
• Leukemia - mogya mu kokoram
• Ntini a ɛma mogya tu

6. Sɛ Nnuru ne Ayaresa Ho Nsunsuanso Foforo

Wobetumi atew lymphocytes so, titiriw esiane kokoram ayaresa ne nnuru bi a wɔde sa nyarewa a nipadua no tumi ko tia nyarewa nti.

• Nnompe mu ntini a wɔde si ananmu
• Nnuru a wɔde sa yare
• Mframa a wɔde sa yare
• Nnuru a ɛma nipadua no tumi ko tia nyarewa - sɛ nhwɛso no, corticosteroids.

7. Esiane Nsã a Ɛyɛ Awuduru nti

Nsã a wɔnom boro so (te sɛ beer, bobesa, ne nsa) nso betumi aka lymphocytes wɔ ɔkwan a enye so, na ama wɔn dodow so atew.

Wobɛyɛ dɛn ahu sɛ wowɔ lymphopenia?

Sɛ wususuw sɛ wowɔ lymphopenia a, ɛbɛyɛ papa sɛ wobɛkɔ oduruyɛfo nkyɛn na woaka ho asɛm. Oduruyɛfo no bebisa w’ayaresa ho abakɔsɛm, mprempren sɛnkyerɛnne ahorow, ne w’asetra kwan ho asɛm. Afei ebia wobetu mmirika ayɛ sɔhwɛ ahorow bi.

Oduruyɛfo nhwehwɛmu ne nsɛmmisa

• Aduruyɛ ho abakɔsɛm: Wo duruyɛfo bebisa wo aduruyɛ ho abakɔsɛm a atwam, nnuru a wode di dwuma mprempren, ne ayaresa ahorow ho asɛm. Sɛ nhwɛso no, sɛ nnansa yi ara na woanya COVID-19 a, ebia wo duruyɛfo besusuw sɛ ɔyare mmoawa bi na ama wo lymphocyte dodow so atew. Sɛ worenom nnuru te sɛ corticosteroids a, ɛno nso betumi ayɛ nea ɛde ba.
• Nipadua mu nhwehwɛmu: Oduruyɛfo no bebisa wo yare no ho sɛnkyerɛnne na wahwɛ nneɛma te sɛ atiridiinini, ntini a ɛho ahonhon, ne akyi berɛmo a ayɛ kɛse anaa.
• Asetra mu nsɛmmisa: Ebia wobebisa wo w’aduan ho asɛm ahwɛ sɛ wowɔ aduannuru bi a enni mu anaa. Wobetumi nso abisa wo wo nna mu asetena ho asɛm (te sɛ sɛ ebia wode akwan a ahobammɔ wom di dwuma anaa) de ayi nyarewa te sɛ HIV afi hɔ.

Sɔhwɛ ahorow bɛn na wɔyɛ?

Nhwehwɛmu ahorow pii wɔ hɔ a wɔde hwehwɛ mogya mu nkwammoaa ne nnompe mu ntini mu.

• Mogya Dodow a Edi Mu (CBC): Eyi kan nkwammoaa ahorow a ɛwɔ wo mogya mu nyinaa dodow (a mogya mu nkwammoaa fitaa ka ho).
• Mogya dodow a edi mũ a nsonsonoe wom (CBC a nsonsonoe wom): Eyi kan mogya mu nkwammoaa fitaa ahorow biara (a mogya mu nkwammoaa kɔkɔɔ ka ho) dodow wɔ ɔkwan soronko so.
• Flow cytometry: Eyi yɛ sɔhwɛ titiriw bi. Etumi susuw ntini nketenkete te sɛ B nkwammoaa, T nkwammoaa, ne NK nkwammoaa no wɔ ɔkwan soronko so.
• Immunoglobulin dodow nhwehwɛmu: Eyi kyerɛ protein dodow a wɔfrɛ no antibodies a ɛwɔ wo mogya mu. Ebetumi aboa ma wɔahu tebea horow pii a ɛbata lymphopenia ho, te sɛ ɔyare mmoawa, nyarewa a nipadua no tumi ko tia nyarewa, ne kokoram.
• Nnompe mu ntini mu nhwehwɛmu: Wɔnyɛ eyi mma obiara, nanso ebia wo duruyɛfo bɛkamfo nhwehwɛmu yi akyerɛ sɛ wosusuw sɛ ɔhaw kɛse bi wɔ lymphocytes a wɔyɛ no mu a.

Bio nso, wobetumi ayɛ nhwehwɛmu afoforo de ahwɛ sɛ nyarewa pɔtee bi a ebetumi de lymphopenia aba (te sɛ HIV nhwehwɛmu, nsamanwaw mu nhwehwɛmu, atiridii nhwehwɛmu, anaa COVID-19 nhwehwɛmu).

Dɛn ne nnuru a wɔde sa lymphopenia?

Mpɛn pii no , lymphopenia a emu nyɛ den, titiriw sɛ sɛnkyerɛnne biara nni hɔ a, enhia ayaresa titiriw biara. Sɛ biribi te sɛ ɔyare mmoawa na ɛde ba a, mogya mu nkwammoaa dodow no bɛsan ayɛ nea ɛfata bere a nipadua no anya ahoɔden afi ɔyare no mu no.

Ade a ɛho hia sen biara ne sɛ wɔsa lymphopenia denam nea ɛde ba no a wɔsa so.

Bere a wo duruyɛfo ahu nea ɛde wo lymphocytes a ɛba fam no ba akyi no, ɔbɛkyerɛ wo ayaresa a ɛfata.

So wobetumi asa Lymphopenia koraa?

Sɛ wɔwoo wo a na wowɔ awosu mu yare bi a ɛmma wuntumi nyɛ lymphocytes yiye a, ɛtɔ mmere bi a ayaresa bi a wɔfrɛ no hematopoietic stem cell transplant betumi ayɛ aduru. Nea ɛka eyi ho ne sɛ wobeyi ntini mu nkwammoaa a ɛyɛ mogya a asɛe anaasɛ asɛe no afi hɔ na wɔde ntini mu nkwammoaa a ɛte apɔw asi ananmu. Afei saa nkwammoaa foforo yi yɛ lymphocytes, ne mogya mu nkwammoaa afoforo nso.

Nanso, eyi yɛ ayaresa a ɛyɛ den kakra, na asiane ahorow wɔ mu. Ɛnyɛ obiara na obetumi ayɛ eyi. Wo duruyɛfo bɛkyerɛ wo sɛ eyi fata wo anaasɛ ɛnsɛ.

Nnuru a wɔde sa yare

Sɛ wowɔ lymphopenia a emu yɛ den, a ɛkyerɛ sɛ wotaa nya nyarewa a, ebia wo duruyɛfo bɛma wo immunoglobulin (IG) nnuru . Saa nnuru yi hyɛ wo nipadua mu ahoɔden a ɛko tia nyarewa no mu den na ɛboa wo ma woko tia nyarewa. Ebia wobetu wo fo nso sɛ kɔ so nom saa IG nnuru yi na amma woannya ɔyare mmoawa a wɔtaa nya no.

So wobetumi asiw lymphopenia ano?

Wontumi nsiw lymphopenia a awosu mu nneɛma de ba no ano. Nanso, nneɛma bi wɔ hɔ a wubetumi ayɛ de atew asiane a ɛwɔ hɔ sɛ wubenya lymphopenia a efi nneɛma afoforo mu ba no so:

• Bɔ wo ho ban fi mmoawa ho: Tu anammɔn biara a wubetumi de abɔ wo ho ban afi mmoawa a wɔde nyarewa ba ho.
• Ɔbarima ne ɔbea nna ho nneyɛe a ahobammɔ wom: Di akwan a ahobammɔ wom akyi na woakwati nna mu nyarewa (STIs) te sɛ HIV.
• Asanom a wosiw ano: Sɛ wonom nsa a, to ano hye. Ɛyɛ papa sɛ worennom beer toa biako, bobesa kuruwa biako, anaa nsa biako da biara.

Sɛ wowɔ lymphopenia a, wobɛyɛ dɛn atumi abɔ wo ho ban afi nyarewa ho?

Sɛ wo lymphocyte dodow sua a, ɛho hia sɛ wobɔ wo ho ban fi nyarewa ho. Nneɛma bi a ebetumi aboa ni:

• Nya vaccination: Nya vaccination ma atiridii ne COVID-19. Bisa wo duruyɛfo no nnuru afoforo a wɔde bɔ wo ho ban ho asɛm.
• Kwati mmeae a asiane a ɛwɔ hɔ sɛ wubenya ɔyare mmoawa no dɔɔso: Twe wo ho fi nnipa a wɔyare anaa wɔn a ebia wɔyare ho. Tew wo ho a wobɛfa wɔ dan mu mmeae a nnipa ahyɛ mu ma na mframa pa nkɔ mu no so.
• Hohoro wo nsa mpɛn pii: Fa samina ne nsu hohoro wo nsa yiye, anaa fa aduru a wɔde tew nsa a nsa wom di dwuma.
• Hyɛ akatasoɔ: Hyɛ akatasoɔ berɛ a worekɔ mmeaeɛ a ebia mmoawa a ɛwɔ mframa mu wɔ hɔ no.
• Aduan mu ahobammɔ: Noa aduan yiye. Hohoro nnuaba ne nhabannuru yiye ansa na woadi.
• Kwati opira: Akuru te sɛ nea wɔatwitwa ne nea wɔatwitwa betumi de mmoawa aba nipadua no mu, enti hwɛ yiye wɔ akwanhyia a ɛtete saa ho.

Nea ɛka eyi ho no, bisa wo duruyɛfo sɛ nneɛma bi wɔ hɔ a ɛsɛ sɛ wohwɛ yiye wɔ ho titiriw anaa.

Nnipa a wɔwɔ lymphopenia no akwahosan te dɛn? (Nsusuwii/Nkɔmhyɛ) .

Eyi gyina nea ɛde wo lymphocytes a ɛba fam ba no so koraa. Mpɛn pii no, sɛ ɔyare mmoawa bi na ɛma ɛso tew a, mogya mu nkwammoaa dodow no bɛsan ayɛ sɛnea na ɛte bere a wɔasa ɔyare no. Nanso, sɛ efi biribi a emu yɛ den kɛse a, ebia ayaresa no bɛkyɛ kakra na ayɛ den.

Mmere bɛn na eye sen biara a wubetumi akɔ oduruyɛfo nkyɛn?

Sɛ wowɔ yareɛ ho sɛnkyerɛnne bi (te sɛ atiridiinini, ɔfe, nipadua mu yaw) a, kɔ oduruyɛfoɔ nkyɛn ntɛm ara. Sɛ wowɔ tebea bi a ɛde wo to asiane mu sɛ wobɛtaa anya ɔyare mmoawa (te sɛ lymphopenia) a, di kan bisa wo duruyɛfo no sɛnkyerɛnne ahorow a ɛsɛ sɛ wohwehwɛ aduruyɛ mu afotu.

So lymphopenia yɛ kokoram?

Dabi, lymphopenia nyɛ kokoram. Nanso, kokoram ahorow bi (e.g. leukemia, lymphoma) betumi asiw lymphocytes a wɔyɛ no kwan, na ɛde lymphopenia aba. Afei nso, kokoram ayaresa ahorow bi (te sɛ nnuru a wɔde sa yare) betumi ama lymphocytes dodow akɔ fam bere tiaa bi.

Nkrasɛm a Wɔde Kɔ Fie

Okay, enti seesei woanya nteaseɛ pa wɔ deɛ yɛkaa ho asɛm nnɛ no ho, Lymphopenia. Kae:

• Lymphopenia yɛ lymphocytes, nkwammoaa bi a ɛko tia nyarewa a ɛwɔ mogya mu no dodow a ɛso tew.
• Eyi nyɛ biribi foforo bi kɛkɛ, ɛtaa fa ɔyare mmoawa, aduannuru a enni nipadua mu, aduru bi a ɛde ɔhaw ba, anaa aduruyɛ mu tebea foforo ho.
• Mpɛn pii no, nsɛm a emu nyɛ den no nkyerɛ yare no ho sɛnkyerɛnne.
• Sɛ wotaa yare, anaasɛ w’adwene mu yɛ wo naa wɔ eyi ho a, ade a eye sen biara a ɛsɛ sɛ woyɛ ne sɛ wobɛkɔ oduruyɛfo nkyɛn akɔhwehwɛ afotu.
• Sɛ wohu nea ɛde ba na wɔsa no yiye a, mpɛn pii no wobetumi adi tebea yi so.

Enti, hwɛ w’akwahosan so yiye. Sɛ wowɔ nsɛmmisa bi a, nsuro sɛ wo ne wo duruyɛfo bɛkasa. Kɔ so nya apɔwmuden!

` Lymphopenia, lymph cells, lymphocytes, mogya mu nkwammoaa fitaa, nipadua mu ahoɔden a ɛko tia nyarewa, ɔyare mmoawa, sɛnkyerɛnne ahorow