So ɛtɔ mmere bi a wote nka sɛ wo ho ayɛ wo yaw na ɛyɛ den sɛ wobɛmene bere a woanom nnuru a ano yɛ den a wɔde kum ɛyaw awie no? Eyi yɛ biribi a ɛto nnipa pii. Enti, wɔ mmere a ɛte sɛɛ mu no, ebia wo duruyɛfo bɛkyerɛw aduru titiriw bi a ɛbɛma woatumi asiw akisikuru yi ano. Ɛnnɛ yɛreka aduru a ɛte saa biako ho asɛm, a ɛne Naloxegol.
Aduru bɛn na Naloxegol yɛ?
Sɛ yɛbɛka no tiawa a, Naloxegol yɛ aduru a ɛboa ma wɔsa akisikuru a ɛba bere a wonom nnuru bi a ano yɛ den a wɔde kum ɛyaw, titiriw opioid nnuru a wɔde kum ɛyaw .
Susuw ho hwɛ, ɛnyɛ sɛ saa opioid nnuru a wɔde kum ɛyaw yi brɛ wo yaw ase nko, na mmom ɛtew wo dwensɔtwaa dwumadi so kakra nso. Ɛno kyerɛ sɛ ntini a ɛwɔ wo dwensɔtwaa mu no twetwe na ɛpia nsu no kɔ w’anim brɛoo kakra. Naloxegol ne nea aduru no yɛ de siesie eyi pɛpɛɛpɛ. Ɛyɛ aduru a ɛka nnuru kuw a wɔfrɛ no Opioid Blockers ho. Nanso ade titiriw a ɛwɔ eyi mu ne sɛ ɛyɛ adwuma titiriw wɔ wo dwensɔtwaa mu nkutoo. Enti, a akwanside kɛse biara nni aduru a wode rema wo yaw no nkɛntɛnso ho no, ɛkɔ dwensɔtwaa mu nkutoo na eyi saa ɛyaw ano aduru no nkɛntɛnso fi hɔ, na ɛboa ntini a ɛwɔ dwensɔtwaa no mu no ma ɛsan yɛ adwuma yiye. Afei ɛbɛyɛ mmerɛw sɛ wobɛfa nsu mu.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woanom saa aduru yi
Ansa na wubefi saa aduru yi ase no, ɛho hia yiye sɛ wobɛma wo duruyɛfo no ahu w’akwahosan ho mfonini a edi mũ. Hwɛ hu sɛ wobɛka akyerɛ wɔn sɛ wowɔ tebea horow a ɛwɔ ase ha no bi a.
- Sɛ wowɔ kokoram anaa akisikuru bi wɔ wo yafunu, wo dwensɔtwaa, anaa wo dwensɔtwaa mu a.
- Sɛ wowɔ tebea bi te sɛ Diverticulitis a .
- Sɛ wo dwensɔtwaa asiw pɛn a.
- Sɛ wowɔ yareɛ bi te sɛ dwensɔtwaa mu yareɛ ( e.g. Crohn yareɛ, ulcerative colitis).
- Sɛ wowɔ asaabo mu yare anaa mmerɛbo mu yare a.
- Sɛ wɔayɛ wo oprehyɛn nnansa yi wɔ wo yafunu anaa wo dwensɔtwaa mu a.
- Sɛ worenom kokoram aduru te sɛ bevacizumab a .
- Sɛ wowɔ Naloxegol anaa aduru foforo biara, aduan, anaa aduru a wɔde yɛ ade ho akisikuru a.
- Sɛ woanyinsɛn, worebɔ mmɔden sɛ wubenyinsɛn, anaa worema nufu a.
Oduruyɛfo no begyina saa nsɛm yi so asi gyinae sɛ ebia saa aduru yi fata wo anaasɛ ɛnfata ne sɛnea wode bɛma.
Ɔkwan bɛn so na ɛsɛ sɛ mede aduru no di dwuma pɛpɛɛpɛ?
Sɛnea ɛbɛyɛ a wubenya w’aduru no so mfaso kɛse no, ɛho hia sɛ wode di dwuma yiye.
1. Bere: Ɛsɛ sɛ wɔnom saa aduru yi pɛnkoro pɛ da biara. Ɛno nso wɔ yafunu a hwee nni mu so.Ɛno kyerɛ sɛ anyɛ yiye koraa no ɛsɛ sɛ wonom dɔnhwerew biako ansa na woadi anɔpaduan, anaasɛ anyɛ yiye koraa no nnɔnhwerew abien wɔ adidi akyi .
2. Sɛnea wobɛfa: Fa nsu kuruwa mene tablet no nyinaa. Mmu, nbubu, anaa nwe tablet no. Nanso, sɛ ɛyɛ den ma wo sɛ wobɛmene aduru no a, wubetumi abubu no yiye na wode apete nsu ɔuns 4 (bɛyɛ mililita 120) mu, na woanom ntɛm ara. Bisa wo duruyɛfo no eyi ho asɛm.
3. Nnuru Afoforo a Wɔde Nnuru Ahorow: Mfa nnuru afoforo a ɛma obi ho yɛ hyew nni dwuma bere a worenom saa aduru yi gye sɛ wo duruyɛfo ka kyerɛ wo. Sɛ wo ho nyɛ wo den bere a woanom saa aduru yi nnafua 3 akyi a, ka kyerɛ wo duruyɛfo. Ebia ɔbɛkyerɛw aduru foforo a wɔde sa akisikuru.
4. Nea ɛho hia yiye: Sɛ wugyae opioid aduru a wɔde kum ɛyaw no a, ɛsɛ sɛ wugyae Naloxegol nso nom . Wɔde saa aduru yi ma akisikuru a opioid no de ba nkutoo. Sɛ wugyae opioid no wie a, worenhia saa aduru yi bio.
Na sɛ menom nnuru pii nso ɛ?
Sɛ wususuw sɛ woanom aduru yi dodo a, mma wo ho nnyɛ wo hu na frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea no ntɛm ara . Anaasɛ kɔ ayaresabea a ɛbɛn wo no Emergency Treatment Unit (ETU) .
Nneɛma afoforo a ebetumi ne aduru yi adi nkitaho (Nkitahodi) .
Naloxegol yɛ aduru a ɛtumi ne nnuru foforɔ di nkitaho, enti ɛho hia sɛ woka nnuru a worenom nyinaa kyerɛ wo duruyɛfoɔ.
| Aduru/aduru ko a wɔde yɛ | Nkyerɛmu |
|---|---|
| Kwati sɛ wode Naloxegol bedi dwuma ne eyinom | |
| Antifungal a ɛko tia fungal | Nnuru te sɛ Ketoconazole ne Itraconazole |
| Nnuru a ekum ɔyare mmoawa | Nnuru te sɛ Clarithromycin ne Telithromycin |
| Nnuru a wɔde sa HIV/AIDS | Nnuru bi a wɔde ko tia ɔyare mmoawa |
| Hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo sɛ wode eyinom redi dwuma a. | |
| Grapefruit nsu a wɔde yɛ | Bobe anaa bobe nsu betumi ne saa aduru yi adi nkitaho. |
| Nnuru afoforo | Nneɛma te sɛ Diltiazem, Verapamil (ma komayare/mogya mmoroso), Carbamazepine (ma akisikuru), Rifampin (ma nsamanwaw), St. John’s Wort (ma adwenemyare). |
| Nnuru afoforo a wɔde siw Opioid ano | Nnuru te sɛ Naloxone ne Naltrexone |
Saa list yi nwie pɛyɛ. Mma wo werɛ mmfi sɛ wobɛka nnuru, nhabannuru, anaa vitamin biara a wobɛnom ho asɛm akyerɛ wo duruyɛfo.
Dɛn ne nsunsuanso bɔne a ebetumi afi mu aba?
Te sɛ aduru biara no, Naloxegol betumi de ɔhaw ahorow aba nnipa binom so.
| Nsunsuanso bɔne | Nea ɛsɛ sɛ wɔyɛ |
|---|---|
| Sɛ eyinom mu bi ba a, gyae aduru no nom na kɔ oduruyɛfo nkyɛn anaa kɔ baabi a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ mu ntɛm ara. | |
| Yafunu mu yaw a emu yɛ den, ɛkɔ so, anaasɛ ɛyɛ kɛse. | Eyi betumi ayɛ sɛnkyerɛnne a anibere wom a ɛkyerɛ sɛ dwensɔtwaa no fasu asɛe (tokuru). |
| Nneɛma a ɛma obi ho yɛ no hyew | Wora mu akisikuru, ɛyaw, anofafa, tɛkrɛma anaa anim a ɛho ahonhon, ɛyɛ den sɛ wobɛhome. |
| Sɛ eyinom kɔ so anaasɛ ɛhaw adwene a, ka kyerɛ wo duruyɛfo. | |
| Yafunu mu yaw, akisikuru, ɔfe | Ebia eyinom so bɛtew bere a nipadua no reyɛ nsakrae wɔ aduru no ho no. |
| Ayamtuo | Eyi yɛ ɔhaw a ɛtaa ba. |
| Gas, tiyɛ | Mpɛn pii no, eyinom nyɛ aniberesɛm. |
| Opioid a wɔtwe wɔn ho fi ho ho sɛnkyerɛnne | Fifiri, awɔw, akisikuru, yafunu mu yaw, ahomegye, ne mmerɛwyɛ. Sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, ka kyerɛ wo duruyɛfo. |
Nkrasɛm a Wɔde Kɔ Fie
- Naloxegol yɛ aduru titiriw bi a wɔde ma akisikuru a opioid nnuru a wɔde kum ɛyaw de ba nkutoo .
- Bere nyinaa nom saa aduru yi bere a wo yafunu da mpan , dɔnhwerew biako ansa na woadi anaa nnɔnhwerew abien wɔ adidi akyi.
- Nea ɛho hia sen biara: Sɛ wugyae aduru a wɔde kum ɛyaw no a, hwɛ hu sɛ wubegyae Naloxegol nso nom.
- Sɛ wo yafunu mu yɛ wo yaw kɛse bere a worenom aduru no a, ebetumi ayɛ nea egye ntɛmpɛ. Gyae aduru no nom ntɛm ara na kɔ ayaresabea bi Dwumadibea a Ɛho Hia Ntɛmntɛm (ETU).
- Ka nnuru, vitamin, ne nhabannuru afoforo a wode redi dwuma nyinaa ho asɛm kyerɛ wo duruyɛfo.
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