Sɛ wo duruyɛfo aka akyerɛ wo anaa w’abusua mu obi sɛ wowɔ Chronic Myelogenous Leukemia (CML), mogya mu kokoram bi a, ebia woate aduru bi a wɔfrɛ no Nilotinib ho asɛm. Eyi yɛ aduru a ɛho hia yiye, a ɛyɛ soronko. Enti ɛnnɛ, yɛbɛka nea ɛsɛ sɛ wuhu bere a wode saa aduru yi redi dwuma, sɛnea wode bedi dwuma yiye, ne nsunsuanso bɔne a wobɛhwɛ kwan no ho asɛm tiawa na emu da hɔ.
Dɛn ne Nilotinib?
Sɛ yɛbɛka no tiawa a, Nilotinib yɛ aduru pɔtee bi a esiw kokoram nkwammoaa nyin ano. Yɛfrɛ saa nnuru ahorow yi "ayaresa a wɔde wɔn ani asi so." Ɛne sɛ, saa aduru yi kɔ protein ahorow bi a ɛwɔ kokoram nkwammoaa mu so tẽẽ, esiw wɔn kwan sɛ wɔnyɛ adwuma, na ɛhwɛ kokoram nkwammoaa mu mpaapaemu ne nyin so.
Wɔde saa aduru yi sa mogya mu kokoram bi a wɔfrɛ no Chronic Myelogenous Leukemia (CML) titiriw . Wɔsan nso di gua wɔ edin Tasigna ase .
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru
Nilotinib yɛ aduru a ano yɛ den yiye. Enti, ansa na wubefi saa ayaresa yi ase no, ɛho behia sɛ wo duruyɛfo nya w’akwahosan ho mfonini a edi mũ. Sɛ wowɔ tebea horow a edidi so yi mu biara a, hwɛ hu sɛ wobɛbɔ wo duruyɛfo amanneɛ.
| Tebea a ebia ɛfa wo ho |
|---|
| Asikyireyareɛ |
| Tebea horow te sɛ komayare, koma a ɛnyɛ adwuma yiye, anaa Long QT syndrome. |
| Mmɛn mu yare |
| Sɛ wowɔ abakɔsɛm a ɛkyerɛ sɛ wowɔ dwensɔtwaa mu yare a. |
| Sɛ potassium anaa magnesium kakraa bi na ɛwɔ wo mogya mu a. |
| Sɛ wowɔ ɔhaw ahorow wɔ mogya a ɛkɔ wo nan mu ho a. |
| Sɛ wɔde oprehyɛn ayi yafunu no koraa (Total Gastrectomy). |
| Sɛ wo ho yɛ wo hyew wɔ nilotinib, lactose, gelatin, anaa aduru anaa aduan foforo biara ho a. |
| Sɛ woanyinsɛn, worebɔ mmɔden sɛ wubenyinsɛn, anaa worema nufu a. |
Ɔkwan bɛn so ankasa na mede saa aduru yi di dwuma?
Sɛnea ɛbɛyɛ na woanya aduru yi so mfaso kɛse no, ɛho hia yiye sɛ wode di dwuma yiye.
- Fa yafunu a hwee nni mu: Eyi ne ade a ɛho hia sen biara. Anyɛ yiye koraa no, ɛsɛ sɛ wonom aduru no dɔnhwerew biako ansa na woadidi anaa nnɔnhwerew abien wɔ adidi akyi. Sɛ obi ne saa aduru yi ka aduan ho a, ebetumi asakra dodow a nipadua no twetwe no na ɛde ɔhaw ahorow a ɛyɛ hu aba.
- Fa nsu kuruwa nom: Fa nsu kuruwa mene capsule no nyinaa.
- Mmu, nbubu, anaa nwe capsule no: Mbubu, nbubu, anaa nwe capsule no.
- Sɛ ɛyɛ den ma wo sɛ wobɛmene a: Nnipa binom wɔ ɔhaw wɔ capsules a wɔbɛmene mu. Sɛ saa a, mma ɛnhaw wo. Fa ahwɛyiye bue capsule no, fa powder no fra apɔw-mu-teɛteɛ teaspoon biako, na mene afrafrade no ntɛm ara . Mfa nsie mfa nni dwuma akyiri yi.
- Kwati grapefruit: Nnom grapefruit nsu anaasɛ nni grapefruit esiane biribiara nti. Ebetumi asesa ɔkwan a aduru no fa so yɛ adwuma wɔ ɔkwan a asiane wom so.
- Bere a wode ne nnuru afoforo bɛnom: Sɛ worenom nnuru a wɔde sa yafunu mu yare a, nnom nnuru te sɛ antacids (e.g., Digene) wɔ nnɔnhwerew 2 mu ansa na woanom saa capsule yi anaasɛ bere a woanom akyi. Fa nnuru te sɛ H2-blockers (e.g., Famotidine) nnɔnhwerew 10 ansa na woanom saa aduru yi anaa nnɔnhwerew 2 akyi. Bisa wo duruyɛfo no ma onsi eyi so dua.
- Fa no bere ano: Bɔ mmɔden sɛ wobɛnom w’aduru no bere koro mu da biara. Mma nnyae w’aduru nom a wo duruyɛfo nka ho afotu.
Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?
Sɛ wopa dose bi a, mmɔ dose a edi hɔ no mmɔho abien da mfa nsiesie. Ɛno betumi ayɛ nea asiane wom. Wo werɛ mfi dodow a woayera no na fa dodow a wɔakyerɛw ama no nkutoo wɔ bere a edi hɔ a wɔahyɛ da ayɛ no mu.
Na sɛ menom nnuru pii nso ɛ?
Sɛ wofa nea ɛboro dodow a wɔakyerɛw ama wo no wɔ akwanhyia mu a, ɛyɛ ntɛmpɛ. Ntɛm ara frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea , anaa kɔ ayaresabea a ɛbɛn wo no Ayaresa a Ɛho Hia Ntɛmntɛm (ETU) .
Nnuru afoforo a ebetumi ne Nilotinib adi nkitaho
Nilotinib yɛ aduru a ɛwɔ tumi kɛse sɛ ɛne nnuru afoforo di nkitaho. Enti, ɛho hia sɛ woka nnuru a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo.
| Mfa Nilotinib nka aduru yi ho. |
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| Cisapride, Dronedarone, Pimozide, Thioridazine, Ziprasidone (nnuru a ɛka koma no bɔ) . |
| Flibanserin, Lomitapide, Saquinavir ne nnuru a wɔde sa yare a wɔfrɛ no Saquinavir |
| Fluconazole, Posaconazole (a ɛko tia ntontom) . |
| Sɛ wode saa nneɛma yi redi dwuma a, ka kyerɛ wo duruyɛfo. |
|---|
| Nnuru a wɔde ko tia HIV/AIDS |
| Nnuru a ekum ɔyare mmoawa te sɛ Clarithromycin ne Erythromycin |
| Nnuru a wɔde sa mogya mmoroso, komayare, ne adwenemyare |
| Nnuru afoforo a ekum fungal te sɛ Ketoconazole, Itraconazole |
| Nnuru a wɔde sa yafunu mu yare (Antacids, Cimetidine, Omeprazole) . |
| Nnuru a ɛma mogya yɛ mmerɛw te sɛ Warfarin |
| Nneɛma a wɔde nhabannuru yɛ te sɛ St. John’s Wort |
Saa nsɛm a wɔahyehyɛ yi mu biara nni hɔ a edi mũ. Enti, ɛho hia ma w’ahobammɔ sɛ wobɛka nnuru, vitamin, nhabannuru, ne nnuru a wɔde di dwuma wɔ amanne kwan so a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo.
Nneɛma bɔne bɛn na ebetumi afi aduru no a wɔnom mu aba?
Te sɛ nnuru biara no, Nilotinib betumi de ɔhaw ahorow aba. Ebi yɛ aniberesɛm, bere a afoforo nso abu so. Nea ɛho hia ne sɛ wubehu eyinom na sɛ ɛho hia a, wobɛyɛ ho biribi ntɛm.
| Nsunsuanso bɔne | Features a ɛsɛ sɛ yɛhwɛ kwan |
|---|---|
| Nsunsuanso bɔne a ɛhwehwɛ sɛ wonya ayaresa ntɛm ara | |
| Nneɛma a ɛma obi ho yɛ no hyew | Wora mu akisikuru, ɛyaw, anim, ano anaa tɛkrɛma a ɛho ahonhon. |
| Mogya a ɛretu | Nsu tuntum anaa mogya, ɔfe a ɛte sɛ kɔfe a wɔayam, nsensanee kɔkɔɔ wɔ honam ani, mogya a ɛyɛ soronko a efi hwene anaa anom. |
| Nsakrae a ɛba koma a ɛbɔ mu | Koko mu yaw, adwenemhaw, koma a ɛbɔ ntɛmntɛm anaasɛ ɛnteɛ, ɔtopae. |
| Mmɛn a wɔapirapira | Nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum, aniwa anaa honam ani yɛ kɔkɔɔ, ɛyaw wɔ yafunu no atifi nifa so, aduan ho akɔnnɔ a ɛyera. |
| Pancreatitis a ɛyɛ yare | Yafunu mu yaw (titiriw a ɛhyerɛn kɔ akyi), ɛyaw a ɛyɛ kɛse bere a woadi akyi, atiridiinini, akisikuru, ɔfe. |
| Nsu a ɛboaboa ano wɔ nipadua no mu (Edema) . | Mu duru a ɛkɔ soro mpofirim, nansoaa, akwaa a ɛho ahonhon, ɛyɛ den sɛ ɔbɛhome. |
| Nsunsuanso bɔne a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo no sɛ ɛkɔ so a | |
| Ɔhaw ahorow a ɛtaa ba | Tiyɛ, akisikuru, ɔfe, akisikuru, akisikuru. |
Hwɛ yiye titiriw bere a wonyinsɛn ne bere a worema nufu no
Eyi yɛ asɛm a ɛho hia paa.
- Nnyinsɛn da bere a worenom Nilotinib no.
- Kwati sɛ wubenyinsɛn anyɛ yiye koraa no nnafua 14 bere a woagyae aduru no akyi .
- Mma wo ba no nufu bere a worenom saa aduru yi ne nnafua 14 bere a woagyae no.
Saa aduru yi betumi apira akokoaa a ɔhyɛ yafunu mu no kɛse, enti wo ne wo duruyɛfo nka eyi ho asɛm pefee.
Nkrasɛm a Wɔde Kɔ Fie
- Fa Nilotinib bere nyinaa bere a wo yafunu da mpan, dɔnhwerew biako ansa na woadi anaa nnɔnhwerew abien wɔ adidi akyi.
- Nni bobe aba anaa nnom ne nsu da.
- Hwɛ hu sɛ wobɛka nnuru afoforo, vitamin, ne nhabannuru a wonom nyinaa ho asɛm akyerɛ wo duruyɛfo.
- Sɛ wunya ɔhaw biara a emu yɛ den te sɛ wo koko mu yaw, ɛyɛ den sɛ wobɛhome, anaa mogya a ɛtɔ soronko a, hwehwɛ aduruyɛfo afotu ntɛm ara.
- Kwati nyinsɛn ne nufu a wobɛma no koraa bere a worenom aduru no ne nnafua 14 bere a woagyae no.
- Mma nnhuruw bere a wo ne oduruyɛfo no kɔ ayaresabea no. Ma wɔnyɛ wo mogya mu nhwehwɛmu sɛnea wɔayɛ nhyehyɛe no.
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