Nea ɛsɛ sɛ wuhu fa kokoram aduru Pacritinib ho

So wo duruyɛfo aka akyerɛ wo anaa obi a ɔwɔ w’abusua mu sɛ mfi ase nnom aduru bi a wɔfrɛ no Pacritinib? Ɛyɛ ade a ɛfata sɛ wubenya nsɛmmisa ne nneɛma bi a ɛhaw wo bere a wote aduru titiriw a ɛte saa ho asɛm no. Enti, ɛnnɛ yɛbɛka biribiara ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw na ɛyɛ adamfofa su so, te sɛ nea saa aduru yi yɛ, sɛnea wɔde di dwuma, ne nea ɛsɛ sɛ wohwɛ yiye wɔ ho.

Dɛn ne aduru yi a wɔfrɛ no Pacritinib?

Sɛ yɛbɛka no tiawa a, Pacritinib yɛ aduru a wɔde sa tebea bi a wɔfrɛ no myelofibrosis . Myelofibrosis yɛ kokoram a ɛba yɛn nnompe mu ntini mu. Wɔ eyi mu no, ntini a ɛyɛ nhama si nkwammoaa a ɛte apɔw a ɛwɔ nnompe mu ntini mu ananmu, na esiw mogya a wɔyɛ no kwan.

Pacritinib ka nnuru bi a wɔfrɛ no kinase inhibitors ho . Fa no sɛ wɔ yɛn nipadua mu nkwammoaa mu no, abɔfo (protein) nketenkete bi wɔ hɔ a ɛkyerɛ sɛ nkwammoaa nyin na wɔnpaapae. Nea aduru yi yɛ ne sɛ egyae protein ahorow bi a ɛboa ma saa nkwammoaa a wɔyare no nyin no dwumadi. Ɛte sɛ nea wodum switch a asɛe wɔ afiri a ɛretu mmirika mu. Wɔ saa kwan yi so no, nkwammoaa a wɔyare no nyin a wobedi so ne aduru yi adwuma titiriw.

Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ase anom nnuru

Ansa na wubefi saa aduru yi ase no, ɛho hia yiye sɛ wo duruyɛfo nya w’akwahosan tebea no ho mfonini a edi mũ. Efisɛ saa nsɛm no na ɛbɛkyerɛ sɛ saa aduru yi fata wo anaa, ne sɛnea ɛsɛ sɛ wɔde ma. Sɛ wowɔ nea edidi so yi bi a, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo.

Ɔkwan bɛn so na wɔde aduru no bedi dwuma yiye?

Ɛho hia yiye sɛ wobɛnom w’aduru no sɛnea wo duruyɛfo akyerɛ wo no pɛpɛɛpɛ, wɔ bere a ɛfata mu.

• Saa aduru yi ba wɔ ɔkwan a ɛyɛ capsule so .
• Fa nsu mene capsule no nyinaa . Mma nwe, mmubu, anaa nbubu da.
• Fa yɛ wo su sɛ wobɛnom w’aduru no bere koro mu da biara. Saa kwan no so no, wo werɛ remfi.
• Wobetumi anom saa aduru yi ansa na wɔadi anaasɛ wɔadi adidi awie.
• Kɔ so nom aduru no kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ gyae.

Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?

Nha wo ho. Sɛ wopa dose bi a, twa so koraa. Fa wo dodow a edi hɔ no wɔ bere a wɔahyɛ da ayɛ no mu. Mfa nnuru abien prɛko pɛ da mfa nsiesie dodow a woayera no.

Na sɛ menom nnuru pii nso ɛ?

Sɛ wususuw sɛ woanom boro dodow a wɔakyerɛw ama wo no a, kɔ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ ntɛm ara.Frɛ telefon so anaa kɔ ayaresabea Emergency Department (ETU) a ɛbɛn wo .

Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho

Ɛho hia paa sɛ wobɛka nnuru a worenom nyinaa (a vitamin, nhabannuru, ne nnuru a wɔde ka ho) ho asɛm kyerɛ wo duruyɛfo, efisɛ nnuru bi betumi ne pacritinib adi nkitaho, asakra ne nkɛntɛnso anaasɛ ama ne nsunsuanso no ayɛ kɛse.

Titiriw no, wɔhyɛ nyansa denneennen sɛ ɛnsɛ sɛ wode pacritinib nka nnuru a edidi so yi ho.

• Nnuru bi a wɔde ko tia HIV anaa AIDS
• Nnuru bi a ekum ɔyare mmoawa, te sɛ clarithromycin ne erythromycin
• Nnuru a wɔde sa fungal yare, te sɛ ketoconazole ne itraconazole
• Nnuru a wɔde ko tia akisikuru te sɛ carbamazepine ne phenytoin
• Rifampin na ɔkyerɛwee
• St. John’s wort nhabannuru aduru

Bio nso, ebetumi ne nnuru afoforo a ebetumi ama nsakrae aba koma no mu no adi nkitaho (ɛma QT ntam kwan no kyɛ). Saa list yi nwie pɛyɛ. Enti hwɛ hu sɛ wobɛka nnuru a wonom nyinaa ho asɛm akyerɛ wo duruyɛfo.

Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho bere a worenom nnuru no

• Hwɛ a wobɛhwɛ wo daa: Wo duruyɛfo bɛka akyerɛ wo sɛ bra ayaresabea hɔ daa nkɔhwɛ wo tebea no. Ɔbɛsan nso ahyɛ sɛ wɔnyɛ mogya mu nhwehwɛmu (mogya adwuma). Mma eyinom nmpa wo ti so na yɛ no daa.
• Asiane a ɛwɔ hɔ sɛ mogya bɛtu: Saa aduru yi betumi ama asiane a ɛwɔ hɔ sɛ mogya bɛtɔ wo anaasɛ wo ho bɛtɔ wo ntɛm no ayɛ kɛse kakra. Sɛ wuhu mogya bi a ɛyɛ soronko (sɛ nhwɛso no, efi wo hwene, wo hwene mu) anaasɛ akuru a emu yɛ den a, ka kyerɛ wo duruyɛfo ntɛm ara.
• Asiane a ɛwɔ hɔ sɛ wubenya ɔyare mmoawa: Ebia saa aduru yi bɛtew wo nipadua mu tumi a ɛko tia nyarewa no dwumadi so kakra. Enti, asiane a ɛwɔ hɔ sɛ obi benya nyarewa no dɔɔso. Sɛ wuhu sɛnkyerɛnne ahorow te sɛ atiridiinini, atiridiinini, menewa mu yaw, ne ɔfe a, nnyɛ wo ho aduru na frɛ wo duruyɛfo. Bɔ mmɔden sɛ wobɛtwe wo ho afi mmeae a ayarefo wɔ.
• Kokoram ho asiane: Adanse bi wɔ hɔ a ɛkyerɛ sɛ saa aduru yi betumi ama asiane a ɛwɔ hɔ sɛ obi benya kokoram ahorow bi no ayɛ kɛse kakra. Wo ne wo duruyɛfo nka eyi ho asɛm na woanya nsɛm pii.
• Nkɛntɛnso a enya wɔ awo so: Saa aduru yi betumi aka mmarima awo. Sɛ wowɔ anidaso sɛ wobɛwo mma a, wo ne wo duruyɛfo nsusuw eyi ho ansa na woafi ayaresa ase.
• Nufu a wɔde ma: Mma wo ba no nufu bere a worenom aduru yi ne adapɛn 2 bere a woagyae aduru no akyi.

Nsunsuanso bɔne a ebetumi aba esiane nnuru nti

Te sɛ aduru biara no, saa aduru yi betumi de ɔhaw ahorow aba nnipa binom so. Nanso, ɛnyɛ obiara na onya bi. Ase hɔ no yɛ nneɛma bɔne a ebetumi afi mu aba no bi.